Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Rachel Lisa Berkowitz, Jeremy D Coplan, Dorothy P Reddy, Jack M Gorma. The human dimension: how the prefrontal cortex modulates the subcortical fear response. Reviews in the neurosciences. vol 18. issue 3-4. 2007-12-21. PMID:18019606. |
thus, we hypothesize that human anxiety disorders are caused at least in part by differential activity in the prefrontal cortex, the brain region that most separates us from our nearest genetic neighbors. |
2007-12-21 |
2023-08-12 |
human |
Rachel Lisa Berkowitz, Jeremy D Coplan, Dorothy P Reddy, Jack M Gorma. The human dimension: how the prefrontal cortex modulates the subcortical fear response. Reviews in the neurosciences. vol 18. issue 3-4. 2007-12-21. PMID:18019606. |
disorders such as generalized anxiety disorder and obsessive-compulsive disorder, which involve worry and rumination, on the other hand, seem to be characterized by an overactivity of the prefrontal cortex. |
2007-12-21 |
2023-08-12 |
human |
Jeremy D Coplan, Sanjay J Mathew, Xiangling Mao, Eric L P Smith, Patrick R Hof, Paul M Coplan, Leonard A Rosenblum, Jack M Gorman, Dikoma C Shung. Decreased choline and creatine concentrations in centrum semiovale in patients with generalized anxiety disorder: relationship to IQ and early trauma. Psychiatry research. vol 147. issue 1. 2006-10-05. PMID:16797939. |
we have demonstrated, using proton magnetic resonance spectroscopy imaging ((1)h-mrsi), elevations of n-acetyl-aspartate/creatine (naa/cr) in right dorsolateral prefrontal cortex (dlpfc) in patients with generalized anxiety disorder (gad) in comparison to healthy volunteers. |
2006-10-05 |
2023-08-12 |
human |
Christopher S Monk, Eric E Nelson, Erin B McClure, Karin Mogg, Brendan P Bradley, Ellen Leibenluft, R James R Blair, Gang Chen, Dennis S Charney, Monique Ernst, Daniel S Pin. Ventrolateral prefrontal cortex activation and attentional bias in response to angry faces in adolescents with generalized anxiety disorder. The American journal of psychiatry. vol 163. issue 6. 2006-07-10. PMID:16741211. |
ventrolateral prefrontal cortex activation and attentional bias in response to angry faces in adolescents with generalized anxiety disorder. |
2006-07-10 |
2023-08-12 |
Not clear |
Gregory J Quirk, Donald R Gehler. Inhibition of the amygdala: key to pathological states? Annals of the New York Academy of Sciences. vol 985. 2003-06-17. PMID:12724164. |
future therapies aimed at increasing inhibitory tone in the amygdala, either locally or via the prefrontal cortex, may prevent anxiety disorders and addiction relapse. |
2003-06-17 |
2023-08-12 |
Not clear |