| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Qiang Yue, Mengqi Liu, Xiaojing Nie, Qizhu Wu, Jun Li, Wei Zhang, Xiaoqi Huang, Qiyong Gon. Quantitative 3.0T MR spectroscopy reveals decreased creatine concentration in the dorsolateral prefrontal cortex of patients with social anxiety disorder. PloS one. vol 7. issue 10. 2013-04-05. PMID:23110183. |
quantitative 3.0t mr spectroscopy reveals decreased creatine concentration in the dorsolateral prefrontal cortex of patients with social anxiety disorder. |
2013-04-05 |
2023-08-12 |
Not clear |
| Jennifer C Britton, Yair Bar-Haim, Frederick W Carver, Tom Holroyd, Maxine A Norcross, Allison Detloff, Ellen Leibenluft, Monique Ernst, Daniel S Pin. Isolating neural components of threat bias in pediatric anxiety. Journal of child psychology and psychiatry, and allied disciplines. vol 53. issue 6. 2012-09-20. PMID:22136196. |
in pediatric anxiety disorders, dot-probe paradigms detect abnormal attention biases toward threat and abnormal ventrolateral prefrontal cortex (vlpfc) function. |
2012-09-20 |
2023-08-12 |
human |
| Xin-jie Tan, Yu-bing Dai, Wan-fu Wu, Margaret Warner, Jan-Åke Gustafsso. Anxiety in liver X receptor β knockout female mice with loss of glutamic acid decarboxylase in ventromedial prefrontal cortex. Proceedings of the National Academy of Sciences of the United States of America. vol 109. issue 19. 2012-08-13. PMID:22529354. |
the prefrontal cortex (pfc), amygdala, and dorsal raphe are known to be involved in anxiety disorders. |
2012-08-13 |
2023-08-12 |
mouse |
| B Myers-Schulz, M Koenig. Functional anatomy of ventromedial prefrontal cortex: implications for mood and anxiety disorders. Molecular psychiatry. vol 17. issue 2. 2012-06-04. PMID:21788943. |
functional anatomy of ventromedial prefrontal cortex: implications for mood and anxiety disorders. |
2012-06-04 |
2023-08-12 |
human |
| B Myers-Schulz, M Koenig. Functional anatomy of ventromedial prefrontal cortex: implications for mood and anxiety disorders. Molecular psychiatry. vol 17. issue 2. 2012-06-04. PMID:21788943. |
one prominent theoretical perspective highlights the top-down inhibition of amygdala by ventromedial prefrontal cortex (vmpfc) as a crucial neural mechanism that may be defective in certain mood and anxiety disorders, such as major depression and post-traumatic stress disorder. |
2012-06-04 |
2023-08-12 |
human |
| Yann Quidé, Anke B Witteveen, Wissam El-Hage, Dick J Veltman, Miranda Olf. Differences between effects of psychological versus pharmacological treatments on functional and morphological brain alterations in anxiety disorders and major depressive disorder: a systematic review. Neuroscience and biobehavioral reviews. vol 36. issue 1. 2012-04-19. PMID:21963442. |
the most prevalent mental disorders, anxiety and mood disorders, are associated with both functional and morphological brain changes that commonly involve the 'fear network' including the (medial) prefrontal cortex, hippocampus and amygdala. |
2012-04-19 |
2023-08-12 |
Not clear |
| Yann Quidé, Anke B Witteveen, Wissam El-Hage, Dick J Veltman, Miranda Olf. Differences between effects of psychological versus pharmacological treatments on functional and morphological brain alterations in anxiety disorders and major depressive disorder: a systematic review. Neuroscience and biobehavioral reviews. vol 36. issue 1. 2012-04-19. PMID:21963442. |
patients suffering from anxiety disorders and major depressive disorder often show excessive amygdala and reduced prefrontal cortex functioning. |
2012-04-19 |
2023-08-12 |
Not clear |
| Michael L Lehmann, Miles Herkenha. Environmental enrichment confers stress resiliency to social defeat through an infralimbic cortex-dependent neuroanatomical pathway. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 16. 2011-06-30. PMID:21508240. |
these data suggest that pathological ventromedial pfc outputs to downstream limbic targets could predispose an individual to anxiety disorders in stressful situations, whereas enhanced ventromedial pfc outputs could convey stress resilience. |
2011-06-30 |
2023-08-12 |
mouse |
| Susan S Kim, Hansen Wang, Xiang-Yao Li, Tao Chen, Valentina Mercaldo, Giannina Descalzi, Long-Jun Wu, Min Zhu. Neurabin in the anterior cingulate cortex regulates anxiety-like behavior in adult mice. Molecular brain. vol 4. 2011-04-18. PMID:21247477. |
despite human brain imaging studies, which have implicated the prefrontal cortex including the anterior cingulate cortex (acc), little is known about the acc in anxiety disorders. |
2011-04-18 |
2023-08-12 |
mouse |
| Frederico G Graeff, Hélio Zangross. The dual role of serotonin in defense and the mode of action of antidepressants on generalized anxiety and panic disorders. Central nervous system agents in medicinal chemistry. vol 10. issue 3. 2011-01-07. PMID:20528764. |
this action would result in less activation of the amygdala, medial pfc and insula by warning signals, as shown by the reviewed results obtained with functional neuroimaging in healthy volunteers and patients with anxiety disorders. |
2011-01-07 |
2023-08-12 |
human |
| Jack M Gorman, John P Dochert. A hypothesized role for dendritic remodeling in the etiology of mood and anxiety disorders. The Journal of neuropsychiatry and clinical neurosciences. vol 22. issue 3. 2010-11-12. PMID:20686132. |
however, depression and anxiety disorders involve multiple areas of the brain, such as the amygdala and prefrontal cortex, where neurogenesis does not appear to occur in the adult mammalian brain. |
2010-11-12 |
2023-08-12 |
Not clear |
| Erin L Zelinski, Nancy S Hong, Amanda V Tyndall, Brett Halsall, Robert J McDonal. Prefrontal cortical contributions during discriminative fear conditioning, extinction, and spontaneous recovery in rats. Experimental brain research. vol 203. issue 2. 2010-08-17. PMID:20449729. |
these results further implicate opfc and i/p pfc in the pathology underlying generalized anxiety disorder. |
2010-08-17 |
2023-08-12 |
rat |
| Maria Vittoria Spampinato, Jacqueline N Wood, Veronica De Simone, Jordan Grafma. Neural correlates of anxiety in healthy volunteers: a voxel-based morphometry study. The Journal of neuropsychiatry and clinical neurosciences. vol 21. issue 2. 2010-04-16. PMID:19622691. |
the authors found an inverse correlation between anxiety measures and cortical volume in regions of the limbic system and prefrontal cortex implicated in the pathogenesis of anxiety disorders. |
2010-04-16 |
2023-08-12 |
human |
| Bernardo Dell'Osso, Massimiliano Buoli, David S Baldwin, A Carlo Altamur. Serotonin norepinephrine reuptake inhibitors (SNRIs) in anxiety disorders: a comprehensive review of their clinical efficacy. Human psychopharmacology. vol 25. issue 1. 2010-03-01. PMID:20041476. |
it is now well established that gabaergic, noradrenergic and serotonergic systems play a critical role in the pathophysiology of anxiety disorders, abnormalities in these systems being related to structural and functional alterations in specific brain areas such as the amygdala, prefrontal cortex, locus coeruleus and hippocampus, as repeatedly shown by neuroimaging studies. |
2010-03-01 |
2023-08-12 |
Not clear |
| Jan Mohlman, Rebecca B Price, Dana A Eldreth, Daniel Chazin, Dorie M Glover, Wendy R Kate. The relation of worry to prefrontal cortex volume in older adults with and without generalized anxiety disorder. Psychiatry research. vol 173. issue 2. 2009-09-15. PMID:19559575. |
the relation of worry to prefrontal cortex volume in older adults with and without generalized anxiety disorder. |
2009-09-15 |
2023-08-12 |
Not clear |
| Nathalie M Goodfellow, Madhurima Benekareddy, Vidita A Vaidya, Evelyn K Lamb. Layer II/III of the prefrontal cortex: Inhibition by the serotonin 5-HT1A receptor in development and stress. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 32. 2009-09-08. PMID:19675243. |
layer ii/iii of the prefrontal cortex, which mediates communication across cortical regions, displays a high level of 5-ht(1a) receptor binding in normal individuals and a significantly lower level in patients with mood and anxiety disorders. |
2009-09-08 |
2023-08-12 |
human |
| Ayse B Tekinay, Yi Nong, Julie M Miwa, Ivo Lieberam, Ines Ibanez-Tallon, Paul Greengard, Nathaniel Heint. A role for LYNX2 in anxiety-related behavior. Proceedings of the National Academy of Sciences of the United States of America. vol 106. issue 11. 2009-04-08. PMID:19246390. |
although roles for the prefrontal cortex, amygdala, hippocampus and mediodorsal thalamus in anxiety disorders are well documented, molecular mechanisms contributing to the functions of these structures are poorly understood. |
2009-04-08 |
2023-08-12 |
mouse |
| Amanda E Guyer, Jennifer Y F Lau, Erin B McClure-Tone, Jessica Parrish, Nina D Shiffrin, Richard C Reynolds, Gang Chen, R J R Blair, Ellen Leibenluft, Nathan A Fox, Monique Ernst, Daniel S Pine, Eric E Nelso. Amygdala and ventrolateral prefrontal cortex function during anticipated peer evaluation in pediatric social anxiety. Archives of general psychiatry. vol 65. issue 11. 2008-11-18. PMID:18981342. |
amygdala and ventrolateral prefrontal cortex (vlpfc) dysfunction manifests in adolescents with anxiety disorders when they view negatively valenced stimuli in threatening contexts. |
2008-11-18 |
2023-08-12 |
Not clear |
| Christopher S Monk, Eva H Telzer, Karin Mogg, Brendan P Bradley, Xiaoqin Mai, Hugo M C Louro, Gang Chen, Erin B McClure-Tone, Monique Ernst, Daniel S Pin. Amygdala and ventrolateral prefrontal cortex activation to masked angry faces in children and adolescents with generalized anxiety disorder. Archives of general psychiatry. vol 65. issue 5. 2008-06-09. PMID:18458208. |
amygdala and ventrolateral prefrontal cortex activation to masked angry faces in children and adolescents with generalized anxiety disorder. |
2008-06-09 |
2023-08-12 |
Not clear |
| Sanjay J Mathew, Rebecca B Price, Dennis S Charne. Recent advances in the neurobiology of anxiety disorders: implications for novel therapeutics. American journal of medical genetics. Part C, Seminars in medical genetics. vol 148C. issue 2. 2008-05-22. PMID:18412102. |
neuroanatomical and neuroimaging research in anxiety disorders has centered on the role of the amygdala, reciprocal connections between the amygdala and the prefrontal cortex, and, most recently, alterations in interoceptive processing by the anterior insula. |
2008-05-22 |
2023-08-12 |
Not clear |