| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hojun Lee, JongKwan Choi, Dooyoung Jung, Ji-Won Hur, Chul-Hyun Ch. The Effects of Virtual Reality (VR) Treatment on Prefrontal Cortex Activity in Patients with Social Anxiety Disorder: fNIRS measurement for VR-derived video exposure. Journal of medical Internet research. 2021-11-21. PMID:34801979. |
the effects of virtual reality (vr) treatment on prefrontal cortex activity in patients with social anxiety disorder: fnirs measurement for vr-derived video exposure. |
2021-11-21 |
2023-08-13 |
Not clear |
| Adrienne C Loewke, Adelaide R Minerva, Alexandra B Nelson, Anatol C Kreitzer, Lisa A Gunaydi. Frontostriatal Projections Regulate Innate Avoidance Behavior. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 41. issue 25. 2021-11-19. PMID:34001628. |
the dorsomedial prefrontal cortex (dmpfc) has been linked to avoidance and decision-making under conflict, key neural computations altered in anxiety disorders. |
2021-11-19 |
2023-08-13 |
mouse |
| Alessandro Pigoni, Giuseppe Delvecchio, Letizia Squarcina, Carolina Bonivento, Paolo Girardi, Livio Finos, Camilla Crisanti, Matteo Balestrieri, Serena D'Agostini, Jeffrey A Stanley, Paolo Brambill. Sex differences in brain metabolites in anxiety and mood disorders. Psychiatry research. Neuroimaging. vol 305. 2021-11-11. PMID:33010582. |
a 3t single-voxel ¹h mrs acquisition of the dorsolateral prefrontal cortex was acquired from 14 major depressive disorder, 10 generalized anxiety disorder (gad), 11 panic disorder (pd), patients and 16 healthy controls (hc). |
2021-11-11 |
2023-08-13 |
Not clear |
| Lu Lu, Jeffrey A Mills, Hailong Li, Heidi K Schroeder, Sarah A Mossman, Sara T Varney, Kim M Cecil, Xiaoqi Huang, Qiyong Gong, Laura B Ramsey, Melissa P DelBello, John A Sweeney, Jeffrey R Straw. Acute Neurofunctional Effects of Escitalopram in Pediatric Anxiety: A Double-Blind, Placebo-Controlled Trial. Journal of the American Academy of Child and Adolescent Psychiatry. vol 60. issue 10. 2021-10-20. PMID:33548492. |
amygdala-ventrolateral prefrontal cortex (vlpfc) circuitry is disrupted in pediatric anxiety disorders, yet how selective serotonin reuptake inhibitors (ssris) affect this circuitry is unknown. |
2021-10-20 |
2023-08-13 |
Not clear |
| Cillian P McDowell, Louise Newman, Derek C Monroe, John D O'Connor, Silvin P Knight, Rose Anne Kenny, Matt P Herrin. The Association Between Generalized Anxiety Disorder and Resting-State Prefrontal Cortex Oxygenation Is Modified by Self-Reported Physical Activity: Results From The Irish Longitudinal Study on Ageing. The journals of gerontology. Series A, Biological sciences and medical sciences. vol 76. issue 8. 2021-10-20. PMID:33780537. |
the association between generalized anxiety disorder and resting-state prefrontal cortex oxygenation is modified by self-reported physical activity: results from the irish longitudinal study on ageing. |
2021-10-20 |
2023-08-13 |
human |
| Cillian P McDowell, Louise Newman, Derek C Monroe, John D O'Connor, Silvin P Knight, Rose Anne Kenny, Matt P Herrin. The Association Between Generalized Anxiety Disorder and Resting-State Prefrontal Cortex Oxygenation Is Modified by Self-Reported Physical Activity: Results From The Irish Longitudinal Study on Ageing. The journals of gerontology. Series A, Biological sciences and medical sciences. vol 76. issue 8. 2021-10-20. PMID:33780537. |
the current study examined the association of generalized anxiety disorder (gad) and its interaction with pa, with resting-state, left pfc oxygenation. |
2021-10-20 |
2023-08-13 |
human |
| Lena Pokorny, Lisa Besting, Friederike Roebruck, Tomasz Antoni Jarczok, Stephan Bende. Fearful facial expressions reduce inhibition levels in the dorsolateral prefrontal cortex in subjects with specific phobia. Depression and anxiety. 2021-10-07. PMID:34617644. |
cognitive control involving the dorsolateral prefrontal cortex (dlpfc) is crucial for coping abilities in anxiety disorders. |
2021-10-07 |
2023-08-13 |
human |
| Ying Sun, Le Ma, Jianhua Chen, Weidi Wang, Shiyu Peng, Ying Cheng, Yu Zhang, Jinghong Chen, Peijun J. RNA-seq co-expression network analysis reveals anxiolytic behavior of mice with Efnb2 knockout in parvalbumin+ neurons. Molecular brain. vol 14. issue 1. 2021-08-12. PMID:34281570. |
anxiety disorders are the most common psychiatric disorders, and the change in the activity of the prefrontal cortex (pfc) is considered as the underlying pathological mechanism. |
2021-08-12 |
2023-08-13 |
mouse |
| Xiaolei Xu, Jing Dai, Yuanshu Chen, Congcong Liu, Fei Xin, Xinqi Zhou, Feng Zhou, Emmanuel A Stamatakis, Shuxia Yao, Lizhu Luo, Yulan Huang, Jinyu Wang, Zhili Zou, Deniz Vatansever, Keith M Kendrick, Bo Zhou, Benjamin Becke. Intrinsic connectivity of the prefrontal cortex and striato-limbic system respectively differentiate major depressive from generalized anxiety disorder. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 46. issue 4. 2021-06-23. PMID:32961541. |
intrinsic connectivity of the prefrontal cortex and striato-limbic system respectively differentiate major depressive from generalized anxiety disorder. |
2021-06-23 |
2023-08-13 |
Not clear |
| Sebastian A Pace, Connor Christensen, Morgan K Schackmuth, Tyler Wallace, Jessica M McKlveen, Will Beischel, Rachel Morano, Jessie R Scheimann, Steven P Wilson, James P Herman, Brent Myer. Infralimbic cortical glutamate output is necessary for the neural and behavioral consequences of chronic stress. Neurobiology of stress. vol 13. 2021-05-14. PMID:33344727. |
human imaging studies have identified structural and functional abnormalities in the prefrontal cortex of subjects with depression and anxiety disorders, particularly brodmann's area 25 (ba25). |
2021-05-14 |
2023-08-13 |
human |
| Anne-Kathrin Brehl, Nils Kohn, Aart Herman Schene, Guillen Fernánde. A mechanistic model for individualised treatment of anxiety disorders based on predictive neural biomarkers. Psychological medicine. vol 50. issue 5. 2021-04-12. PMID:32204741. |
first-line treatment for anxiety disorders is exposure-based cognitive behavioural therapy, which strengthens pfc recruitment during emotion regulation and thus targets low-prefrontal control. |
2021-04-12 |
2023-08-13 |
Not clear |
| Anne Teissier, Corentin Le Magueresse, Jimmy Olusakin, Belmira L S Andrade da Costa, Angela M De Stasi, Alberto Bacci, Yuka Imamura Kawasawa, Vidita A Vaidya, Patricia Gaspa. Early-life stress impairs postnatal oligodendrogenesis and adult emotional behaviour through activity-dependent mechanisms. Molecular psychiatry. vol 25. issue 6. 2021-03-10. PMID:31439936. |
exposure to stress during early life (infancy/childhood) has long-term effects on the structure and function of the prefrontal cortex (pfc), and increases the risk for adult depression and anxiety disorders. |
2021-03-10 |
2023-08-13 |
Not clear |
| D Porta-Casteràs, M A Fullana, D Tinoco, I Martínez-Zalacaín, J Pujol, D J Palao, C Soriano-Mas, B J Harrison, E Via, N Cardone. Prefrontal-amygdala connectivity in trait anxiety and generalized anxiety disorder: Testing the boundaries between healthy and pathological worries. Journal of affective disorders. vol 267. 2021-02-15. PMID:32217221. |
current brain-based theoretical models of generalized anxiety disorder (gad) suggest a dysfunction of amygdala-ventromedial prefrontal cortex emotional regulatory mechanisms. |
2021-02-15 |
2023-08-13 |
Not clear |
| Katie L Burkhouse, Jagan Jimmy, Nicholas Defelice, Heide Klumpp, Olusola Ajilore, Bobby Hosseini, Kate D Fitzgerald, Christopher S Monk, K Luan Pha. Nucleus accumbens volume as a predictor of anxiety symptom improvement following CBT and SSRI treatment in two independent samples. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 45. issue 3. 2020-12-28. PMID:31756730. |
we examined whether gray matter volume of three neural regions supporting fear and avoidance responses [bilateral amygdala, nucleus accumbens (nacc), and ventromedial prefrontal cortex (pfc)] predicted cognitive-behavioral therapy (cbt) and selective serotonin reuptake inhibitor (ssri) treatment outcome in two independent samples of patients with anxiety disorders. |
2020-12-28 |
2023-08-13 |
Not clear |
| Zuzanna M Stawicka, Roohollah Massoudi, Nicole K Horst, Ken Koda, Philip L R Gaskin, Laith Alexander, Andrea M Santangelo, Lauren McIver, Gemma J Cockcroft, Christian M Wood, Angela C Robert. Ventromedial prefrontal area 14 provides opposing regulation of threat and reward-elicited responses in the common marmoset. Proceedings of the National Academy of Sciences of the United States of America. vol 117. issue 40. 2020-11-24. PMID:32958652. |
the ventromedial prefrontal cortex (vmpfc) is a key brain structure implicated in mood and anxiety disorders, based primarily on evidence from correlational neuroimaging studies. |
2020-11-24 |
2023-08-13 |
marmoset |
| Jeffrey R Strawn, Kelli C Dominick, Luis R Patino, Christopher D Doyle, Lara S Picard, K Luan Pha. Neurobiology of Pediatric Anxiety Disorders. Current behavioral neuroscience reports. vol 1. issue 3. 2020-10-01. PMID:25745592. |
in this regard, both structural and functional neuroimaging studies have demonstrated neuroanatomic and functional abnormalities within the amygdala and prefrontal cortex in youth with fear-based anxiety disorders, and have also suggested altered functional connectivity among components of the anterior limbic network (aln), as well as alterations in neurochemistry within the anterior cingulate cortex. |
2020-10-01 |
2023-08-13 |
Not clear |
| Wei Li, Huiru Cui, Zhipei Zhu, Li Kong, Qian Guo, Yikang Zhu, Qiang Hu, Lanlan Zhang, Hui Li, Qingwei Li, Jiangling Jiang, Jordan Meyers, Jianqi Li, Jijun Wang, Zhi Yang, Chunbo L. Aberrant Functional Connectivity between the Amygdala and the Temporal Pole in Drug-Free Generalized Anxiety Disorder. Frontiers in human neuroscience. vol 10. 2020-09-30. PMID:27867352. |
the amygdala and the dorsolateral prefrontal cortex (dlpfc) play important roles in "emotion dysregulation," which has a profound impact on etiologic research of generalized anxiety disorder (gad). |
2020-09-30 |
2023-08-13 |
human |
| Feng Zhou, Yayuan Geng, Fei Xin, Jialin Li, Pan Feng, Congcong Liu, Weihua Zhao, Tingyong Feng, Adam J Guastella, Richard P Ebstein, Keith M Kendrick, Benjamin Becke. Human Extinction Learning Is Accelerated by an Angiotensin Antagonist via Ventromedial Prefrontal Cortex and Its Connections With Basolateral Amygdala. Biological psychiatry. vol 86. issue 12. 2020-09-29. PMID:31471037. |
deficient extinction learning and threat adaptation in the ventromedial prefrontal cortex (vmpfc)-amygdala circuitry strongly impede the efficacy of exposure-based interventions in anxiety disorders. |
2020-09-29 |
2023-08-13 |
human |
| Mengshi Dong, Likun Xia, Min Lu, Chao Li, Ke Xu, Lina Zhan. A failed top-down control from the prefrontal cortex to the amygdala in generalized anxiety disorder: Evidence from resting-state fMRI with Granger causality analysis. Neuroscience letters. vol 707. 2020-03-11. PMID:31163226. |
a failed top-down control from the prefrontal cortex to the amygdala in generalized anxiety disorder: evidence from resting-state fmri with granger causality analysis. |
2020-03-11 |
2023-08-13 |
Not clear |
| Mengshi Dong, Likun Xia, Min Lu, Chao Li, Ke Xu, Lina Zhan. A failed top-down control from the prefrontal cortex to the amygdala in generalized anxiety disorder: Evidence from resting-state fMRI with Granger causality analysis. Neuroscience letters. vol 707. 2020-03-11. PMID:31163226. |
in generalized anxiety disorder (gad), abnormal top-down control from the prefrontal cortex (pfc) to the amygdala is a widely accepted hypothesis through which an "emotional dysregulation model" may be explained. |
2020-03-11 |
2023-08-13 |
Not clear |