| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| W C Drevet. Prefrontal cortical-amygdalar metabolism in major depression. Annals of the New York Academy of Sciences. vol 877. 1999-08-10. PMID:10415674. |
functional neuroimaging studies of the anatomical correlates of familial major depressive disorder (mdd) and bipolar disorder (bd) have identified abnormalities of resting blood flow (bf) and glucose metabolism in depression in the amygdala and the orbital and medial prefrontal cortical (pfc) areas that are extensively connected with the amygdala. |
1999-08-10 |
2023-08-12 |
Not clear |
| J H Meyer, S Kapur, S Houle, J DaSilva, B Owczarek, G M Brown, A A Wilson, S H Kenned. Prefrontal cortex 5-HT2 receptors in depression: an [18F]setoperone PET imaging study. The American journal of psychiatry. vol 156. issue 7. 1999-07-30. PMID:10401447. |
prefrontal cortex 5-ht2 receptors in depression: an [18f]setoperone pet imaging study. |
1999-07-30 |
2023-08-12 |
Not clear |
| R J Davidson, H Abercrombie, J B Nitschke, K Putna. Regional brain function, emotion and disorders of emotion. Current opinion in neurobiology. vol 9. issue 2. 1999-06-15. PMID:10322186. |
particular emphasis has been placed on the prefrontal cortex, anterior cingulate, parietal cortex, and the amygdala as critical components of the circuitry that may be dysfunctional in both depression and anxiety. |
1999-06-15 |
2023-08-12 |
Not clear |
| M J Webster, M P Vawter, W J Free. Immunohistochemical localization of the cell adhesion molecules Thy-1 and L1 in the human prefrontal cortex patients with schizophrenia, bipolar disorder, and depression. Molecular psychiatry. vol 4. issue 1. 1999-05-07. PMID:10089008. |
immunohistochemical localization of the cell adhesion molecules thy-1 and l1 in the human prefrontal cortex patients with schizophrenia, bipolar disorder, and depression. |
1999-05-07 |
2023-08-12 |
human |
| M J Webster, M P Vawter, W J Free. Immunohistochemical localization of the cell adhesion molecules Thy-1 and L1 in the human prefrontal cortex patients with schizophrenia, bipolar disorder, and depression. Molecular psychiatry. vol 4. issue 1. 1999-05-07. PMID:10089008. |
quantifying the intensity of immunostaining in the prefrontal cortex of patients with schizophrenia, bipolar disorder and depression failed to reveal any significant differences when compared to that of normal controls. |
1999-05-07 |
2023-08-12 |
human |
| H Kishimoto, K Yamada, E Iseki, K Kosaka, T Okosh. Brain imaging of affective disorders and schizophrenia. Psychiatry and clinical neurosciences. vol 52 Suppl. 1999-04-07. PMID:9895149. |
one study used fluorine-18-labeled deoxyglucose positron emission tomography (pet) in patients with unipolar depression and bipolar depression, and found hypometabolism in the left anterolateral prefrontal cortex. |
1999-04-07 |
2023-08-12 |
human |
| P Hrdina, G Faludi, Q Li, C Bendotti, K Tekes, P Sotonyi, M Palkovit. Growth-associated protein (GAP-43), its mRNA, and protein kinase C (PKC) isoenzymes in brain regions of depressed suicides. Molecular psychiatry. vol 3. issue 5. 1998-12-14. PMID:9774774. |
given the role of gap-43 in the establishment and reorganization of synaptic connections, the finding of selective reduction of this protein in prefrontal cortex suggests that a dysfunctional synaptic organization in this region may be associated with depression and suicidal behaviour. |
1998-12-14 |
2023-08-12 |
Not clear |
| W C Drevets, D Ongür, J L Pric. Reduced glucose metabolism in the subgenual prefrontal cortex in unipolar depression. Molecular psychiatry. vol 3. issue 3. 1998-10-08. PMID:9672886. |
reduced glucose metabolism in the subgenual prefrontal cortex in unipolar depression. |
1998-10-08 |
2023-08-12 |
Not clear |
| C A Stockmeie. Neurobiology of serotonin in depression and suicide. Annals of the New York Academy of Sciences. vol 836. 1998-06-24. PMID:9616801. |
in suicide victims with major depression and psychiatrically normal control subjects, we have examined various indices of serotonergic neurotransmission in axonal projection areas such as prefrontal cortex and hippocampus, and cell bodies of origin within the dorsal raphe nucleus (dr). |
1998-06-24 |
2023-08-12 |
human |
| C A Stockmeie. Neurobiology of serotonin in depression and suicide. Annals of the New York Academy of Sciences. vol 836. 1998-06-24. PMID:9616801. |
although there were no significant differences between suicide victims with major depression and psychiatrically normal control subjects in serotonin-1a or serotonin-2a receptors in the right prefrontal cortex (area 10) or the hippocampus, there were region-specific alterations in suicide victims with major depression in g-protein-induced activation of the phosphoinositide signal transduction system and in the levels of g-protein alpha subunits involved in cyclic amp synthesis. |
1998-06-24 |
2023-08-12 |
human |
| G Rajkowsk. Morphometric methods for studying the prefrontal cortex in suicide victims and psychiatric patients. Annals of the New York Academy of Sciences. vol 836. 1998-06-24. PMID:9616803. |
neurochemical studies demonstrate altered numbers of monoaminergic receptors in the prefrontal cortex in suicide and depression victims, implicating dysfunction of the prefrontal cortex in the neuropathology of suicide and psychiatric disorders. |
1998-06-24 |
2023-08-12 |
human |
| G Rajkowsk. Morphometric methods for studying the prefrontal cortex in suicide victims and psychiatric patients. Annals of the New York Academy of Sciences. vol 836. 1998-06-24. PMID:9616803. |
in another population of suicide victims with major depression (nonpsychotic), further morphopathological differences from scz and similarities to bipolar disorder were observed in the prefrontal cortex. |
1998-06-24 |
2023-08-12 |
human |
| J N Joyce, S G Goldsmith, E V Gurevic. Limbic circuits and monoamine receptors: dissecting the effects of antipsychotics from disease processes. Journal of psychiatric research. vol 31. issue 2. 1997-10-23. PMID:9278186. |
the limbic loop interconnecting the pfc and ventral striatum may be the site of antipsychotic regulation of certain symptoms in schizophrenia, particularly anhedonia and depression. |
1997-10-23 |
2023-08-12 |
Not clear |
| V Geller, N Grisaru, J M Abarbanel, T Lemberg, R H Belmake. Slow magnetic stimulation of prefrontal cortex in depression and schizophrenia. Progress in neuro-psychopharmacology & biological psychiatry. vol 21. issue 1. 1997-06-27. PMID:9075260. |
slow magnetic stimulation of prefrontal cortex in depression and schizophrenia. |
1997-06-27 |
2023-08-12 |
Not clear |
| G Flügge, O Ahrens, E Fuch. Monoamine receptors in the prefrontal cortex of Tupaia belangeri during chronic psychosocial stress. Cell and tissue research. vol 288. issue 1. 1997-06-20. PMID:9042767. |
the prefrontal cortex has been reported to be involved in the regulation of emotional behaviour by integrating cognitive, emotional and autonomic information processes, and impairments of its functions are implicated in psychopathologies such as depression. |
1997-06-20 |
2023-08-12 |
Not clear |
| J D Bremner, R B Innis, R M Salomon, L H Staib, C K Ng, H L Miller, R A Bronen, J H Krystal, J Duncan, D Rich, L H Price, R Malison, H Dey, R Soufer, D S Charne. Positron emission tomography measurement of cerebral metabolic correlates of tryptophan depletion-induced depressive relapse. Archives of general psychiatry. vol 54. issue 4. 1997-04-25. PMID:9107153. |
positron emission tomography and single photon emission computed tomography studies implicated the dorsolateral prefrontal cortex, orbitofrontal cortex, thalamus, and caudate nucleus in the pathogenesis of depression. |
1997-04-25 |
2023-08-12 |
Not clear |
| C A Stockmeier, G E Dilley, L A Shapiro, J C Overholser, P A Thompson, H Y Meltze. Serotonin receptors in suicide victims with major depression. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 16. issue 2. 1997-04-15. PMID:9015799. |
there were no significant differences between suicide victims with major depression and comparison subjects in 5-ht1a or 5-ht2a receptors in area 10 of the right prefrontal cortex or the hippocampus. |
1997-04-15 |
2023-08-12 |
human |
| C A Stockmeier, G E Dilley, L A Shapiro, J C Overholser, P A Thompson, H Y Meltze. Serotonin receptors in suicide victims with major depression. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 16. issue 2. 1997-04-15. PMID:9015799. |
the current results suggest that the number of 5-ht1a and 5-ht2a receptors in the right prefrontal cortex (area 10) or hippocampus are not different in suicide victims with major depression. |
1997-04-15 |
2023-08-12 |
human |
| H Ito, R Kawashima, S Awata, S Ono, K Sato, R Goto, M Koyama, M Sato, H Fukud. Hypoperfusion in the limbic system and prefrontal cortex in depression: SPECT with anatomic standardization technique. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. vol 37. issue 3. 1997-01-06. PMID:8772633. |
hypoperfusion in the limbic system and prefrontal cortex in depression: spect with anatomic standardization technique. |
1997-01-06 |
2023-08-12 |
Not clear |
| M A Pacheco, C Stockmeier, H Y Meltzer, J C Overholser, G E Dilley, R S Jop. Alterations in phosphoinositide signaling and G-protein levels in depressed suicide brain. Brain research. vol 723. issue 1-2. 1996-12-03. PMID:8813380. |
the function of the phosphoinositide signal transduction system and the levels of heterotrimeric g-protein alpha-subunits were examined in postmortem prefrontal cortex regions (8/9) and region (10) from suicide victims with major depression and matched control subjects without psychiatric illness. |
1996-12-03 |
2023-08-12 |
human |