Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
M A Pacheco, C Stockmeier, H Y Meltzer, J C Overholser, G E Dilley, R S Jop. Alterations in phosphoinositide signaling and G-protein levels in depressed suicide brain. Brain research. vol 723. issue 1-2. 1996-12-03. PMID:8813380. |
these results demonstrate that in the prefrontal cortex of suicide victims with major depression compared to normal control subjects there is a region-specific alteration of g-protein-induced activation of the phosphoinositide signal transduction system and in the levels of g-protein alpha-subunits involved in cyclic amp synthesis. |
1996-12-03 |
2023-08-12 |
human |
b' A Pascual-Leone, B Rubio, F Pallard\\xc3\\xb3, M D Catal\\xc3\\xa. Rapid-rate transcranial magnetic stimulation of left dorsolateral prefrontal cortex in drug-resistant depression. Lancet (London, England). vol 348. issue 9022. 1996-08-22. PMID:8684201.' |
rapid-rate transcranial magnetic stimulation of left dorsolateral prefrontal cortex in drug-resistant depression. |
1996-08-22 |
2023-08-12 |
human |
O Moreaud, B Naegele, J P Chabannes, J L Roulin, B Garbolino, J Pella. [Frontal lobe dysfunction and depressive state: relation to endogenous character of depression]. L'Encephale. vol 22. issue 1. 1996-08-19. PMID:8681875. |
a dysfunction of dorsolateral prefrontal cortex (dlpf) in major depression is suggested by functional imagery and comparative neuropsychology. |
1996-08-19 |
2023-08-12 |
human |
M S George, E M Wassermann, W A Williams, A Callahan, T A Ketter, P Basser, M Hallett, R M Pos. Daily repetitive transcranial magnetic stimulation (rTMS) improves mood in depression. Neuroreport. vol 6. issue 14. 1996-02-22. PMID:8547583. |
converging evidence points to hypofunction of the left prefrontal cortex in depression. |
1996-02-22 |
2023-08-12 |
human |
C J Bench, R S Frackowiak, R J Dola. Changes in regional cerebral blood flow on recovery from depression. Psychological medicine. vol 25. issue 2. 1995-10-17. PMID:7675913. |
we have previously described focal abnormalities of regional cerebral blood flow (rcbf) in the left dorsolateral prefrontal cortex (dlpfc), anterior cingulate cortex and angular gyrus in 40 patients with major depression. |
1995-10-17 |
2023-08-12 |
Not clear |
C Trichard, J L Martinot, M Alagille, M C Masure, P Hardy, D Ginestet, A Félin. Time course of prefrontal lobe dysfunction in severely depressed in-patients: a longitudinal neuropsychological study. Psychological medicine. vol 25. issue 1. 1995-07-24. PMID:7792365. |
vft impairment is consistent with the hypothesis of a left prefrontal cortex dysfunction in depression. |
1995-07-24 |
2023-08-12 |
Not clear |
R J Dolan, C J Bench, P F Liddle, K J Friston, C D Frith, P M Grasby, R S Frackowia. Dorsolateral prefrontal cortex dysfunction in the major psychoses; symptom or disease specificity? Journal of neurology, neurosurgery, and psychiatry. vol 56. issue 12. 1994-01-31. PMID:8270929. |
neurophysiological deficits in the left dorsolateral prefrontal cortex (dlpfc) have been described in positron emission tomography studies of schizophrenia and depression. |
1994-01-31 |
2023-08-12 |
human |
K M Yazici, O Kapucu, B Erbas, E Varoglu, C Gülec, C F Bekdi. Assessment of changes in regional cerebral blood flow in patients with major depression using the 99mTc-HMPAO single photon emission tomography method. European journal of nuclear medicine. vol 19. issue 12. 1993-01-21. PMID:1464356. |
the severity of depression is correlated with the reduction in cbf in the regions of the anterofrontal and left prefrontal cortex. |
1993-01-21 |
2023-08-11 |
human |
M Mintz, L Reyneke, A de Villiers, R Allin, V Russell, W Daniels, G van der Spuy, A Jaffer, L Kellaway, R Dougla. Effect of amygdaloid kindling on [3H]dopamine and [14C]acetylcholine release from rat prefrontal cortex and striatal slices. Brain research. vol 592. issue 1-2. 1993-01-06. PMID:1450903. |
long-term effects of kindling consisted of facilitation of ach release in the ventral striatum contralateral to the kindled amygdala and bilateral depression of da release in the prefrontal cortex. |
1993-01-06 |
2023-08-11 |
rat |
F A Wiese. Glucose metabolism in psychiatric disorders: how can we facilitate comparisons among studies? Journal of neural transmission. Supplementum. vol 37. 1992-11-17. PMID:1402849. |
depression probably involves dysfunction of the metabolism in dorsolateral prefrontal cortex. |
1992-11-17 |
2023-08-11 |
human |
W C Drevets, T O Videen, J L Price, S H Preskorn, S T Carmichael, M E Raichl. A functional anatomical study of unipolar depression. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 12. issue 9. 1992-10-19. PMID:1527602. |
these data along with other evidence suggest that a circuit involving the prefrontal cortex, amygdala, and related parts of the striatum, pallidum, and medial thalamus is involved in the functional neuroanatomy of depression. |
1992-10-19 |
2023-08-11 |
human |
A Biegon, S Fieldus. Reduced tyrosine hydroxylase immunoreactivity in locus coeruleus of suicide victims. Synapse (New York, N.Y.). vol 10. issue 1. 1992-03-24. PMID:1346945. |
reduced th availability, either genetically or environmentally determined, may contribute to the noradrenergic insufficiency postulated to occur in depression and the increased beta-adrenergic receptor concentrations observed in prefrontal cortex of suicide victims. |
1992-03-24 |
2023-08-11 |
human |
M Fujiwara, K Mitsui, J Ishida, I Yamamot. The effect of salazosulfapyridine on the in vitro antibody production in murine spleen cells. Immunopharmacology. vol 19. issue 1. 1990-04-10. PMID:1968449. |
further, this drug did not show any depression of the anti-srbc plaque-forming cell (pfc) response in spleen cells treated with anti-thy1.2 antibody plus complement. |
1990-04-10 |
2023-08-11 |
Not clear |
L R Baxter, J M Schwartz, M E Phelps, J C Mazziotta, B H Guze, C E Selin, R H Gerner, R M Sumid. Reduction of prefrontal cortex glucose metabolism common to three types of depression. Archives of general psychiatry. vol 46. issue 3. 1989-04-05. PMID:2784046. |
reduction of prefrontal cortex glucose metabolism common to three types of depression. |
1989-04-05 |
2023-08-11 |
human |
L R Baxter, J M Schwartz, M E Phelps, J C Mazziotta, B H Guze, C E Selin, R H Gerner, R M Sumid. Reduction of prefrontal cortex glucose metabolism common to three types of depression. Archives of general psychiatry. vol 46. issue 3. 1989-04-05. PMID:2784046. |
mean (+/- sd) glucose metabolic rates for the left dorsal anterolateral prefrontal cortex, divided by the rate for the ipsilateral hemisphere as a whole (alpfc/hem), were similar in the primary depressions (unipolar depression = 1.05 +/- 0.05; bipolar depression = 1.04 +/- 0.05), and were significantly lower than those in normal controls (1.12 +/- 0.06) or ocd without depression (1.15 +/- 0.05). |
1989-04-05 |
2023-08-11 |
human |
A Gabrielli, R Silver, G Teti, M S Chiofalo, A Misefari, D Venza-Teti, G Virella, M F La Vi. Depression by Fc gamma receptor ligands of SRBC-induced IgM-PFC generation in human blood mononuclear cell cultures. Diagnostic and clinical immunology. vol 5. issue 6. 1989-03-21. PMID:2975532. |
heat-aggregated human igg or immune complexes present for the duration of culture induce a significant depression of pfc. |
1989-03-21 |
2023-08-11 |
human |
A Gabrielli, R Silver, G Teti, M S Chiofalo, A Misefari, D Venza-Teti, G Virella, M F La Vi. Depression by Fc gamma receptor ligands of SRBC-induced IgM-PFC generation in human blood mononuclear cell cultures. Diagnostic and clinical immunology. vol 5. issue 6. 1989-03-21. PMID:2975532. |
the results of these experiments are compatible with previous results in a murine system, which indicated that fc gamma receptor-positive (fc gamma r+) cells in the suppressor subset are the target for aggregated igg and induce depression of the pfc response. |
1989-03-21 |
2023-08-11 |
human |
L E McCoy, L A Elliott, C E Lucas, A M Ledgerwoo. Regenerative responses to exchange perfusion. Biomaterials, artificial cells, and artificial organs. vol 16. issue 1-3. 1988-12-08. PMID:3179490. |
similar responses were observed in a study of pfc resuscitation of hemorrhagic shock in splenectomized dogs in which there was a selective depression of the platelets, the plasma globulins, igg and fibrinogen. |
1988-12-08 |
2023-08-11 |
rat |
A E Alito, H E Romeo, R Baler, H E Chuluyan, M Braun, D P Cardinal. Autonomic nervous system regulation of murine immune responses as assessed by local surgical sympathetic and parasympathetic denervation. Acta physiologica et pharmacologica latinoamericana : organo de la Asociacion Latinoamericana de Ciencias Fisiologicas y de la Asociacion Latinoamericana de Farmacologia. vol 37. issue 3. 1988-11-03. PMID:3332531. |
in mice challenged with srbc at an early phase of sympathetic nerve paralysis (i.e., 2 h after scgx), pfc response was already increased in the ipsilateral smln whereas during the anterograde degeneration of nerve endings (6-24 h after scgx) an impending depression of pfc number was observed. |
1988-11-03 |
2023-08-11 |
mouse |
P N Shek, T M Eastma. Effect of diisopropylfluorophosphate on the antibody response. Immunopharmacology. vol 15. issue 3. 1988-08-19. PMID:3292454. |
the dfp-mediated depression of the pfc response to srbc was still evident when dfp was given as early as 1 day before, but not 1 day after, the injection of antigen, suggesting that dfp may well affect an early event of the antibody response. |
1988-08-19 |
2023-08-11 |
mouse |