| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| P N Shek, T M Eastma. Effect of diisopropylfluorophosphate on the antibody response. Immunopharmacology. vol 15. issue 3. 1988-08-19. PMID:3292454. |
for the secondary tnp-specific igm pfc response, a significant depression was observed only when dfp was administered at the time of antigen challenge. |
1988-08-19 |
2023-08-11 |
mouse |
| M R Palmer, O Tottmar, R A Deitric. Electrophysiological effects of monoamine-derived aldehydes on single neurons in neocortex and cerebellum in rats. Alcoholism, clinical and experimental research. vol 10. issue 6. 1987-03-18. PMID:2433956. |
serotonin and 5-hydroxy-3-acetaldehyde caused pronounced depression of firing rates both of cerebellar purkinje neurons and neurons in prefrontal cortex. |
1987-03-18 |
2023-08-11 |
rat |
| R A Lubet, B N Lemaire, D Avery, R E Kour. Induction of immunotoxicity in mice by polyhalogenated biphenyls. Archives of toxicology. vol 59. issue 2. 1986-10-23. PMID:3092783. |
these studies showed: the immunotoxicity results paralleled enzyme induction results insofar as hbb was approximately 100 times more potent than aroclor 1254; neither aroclor nor hbb treatment caused significant induction in the ah locus negative dba/2n mice; when b6c3f1 mice were challenged with sheep red blood cells (srbc) 6 or 16 weeks post aroclor 1254 treatment, substantial recovery of a pfc response was observed; when these compounds were administered to older (76-week-old) (b6c3f1 mice, severe depression of a pfc response was observed. |
1986-10-23 |
2023-08-11 |
mouse |
| R A Lubet, B N Lemaire, D Avery, R E Kour. Induction of immunotoxicity in mice by polyhalogenated biphenyls. Archives of toxicology. vol 59. issue 2. 1986-10-23. PMID:3092783. |
in contrast to its profound depression of a pfc response, aroclor-1254 (up to 1250 mg/kg) caused slight increases in lymphocyte proliferation induced by either t or b cell mitogens. |
1986-10-23 |
2023-08-11 |
mouse |
| P Urso, N Gengozian, R M Rossi, R A Johnso. Suppression of humoral and cell-mediated immune responses in vitro by benzo(a)pyrene. Journal of immunopharmacology. vol 8. issue 2. 1986-08-14. PMID:2941486. |
inhibition of the pfc response and the mlr occurred when spleen cells were exposed to a wide range of bap concentrations from 10(-4) m to 10(-8) m. maximum depression of the responses occurred at 10(-5) m for pfc production (47% of controls) and for the mlr (19% of controls) as measured by a stimulation index. |
1986-08-14 |
2023-08-11 |
Not clear |
| H Hojo, Y Kondo, H Umeda, T Tahira, Y Hashimot. Effect of sinomenine on antibody responses in mice. Journal of immunopharmacology. vol 7. issue 1. 1985-08-01. PMID:3874242. |
the depression of the pfc response induced with sinomenine was dose and time dependent. |
1985-08-01 |
2023-08-11 |
mouse |
| M F La Via, A Misefari, D Venza-Teti, G Teti, A Gabrielli, I Paves. Depression of direct plaque-forming cell response in mouse spleen cell cultures by aggregated IgG2b-induced factors. Immunology letters. vol 8. issue 4. 1985-01-03. PMID:6238906. |
when supernatant from cells cultured with igg2b was added to immunized cultures this resulted in depression of pfc generation similar to that observed by addition of treated cells. |
1985-01-03 |
2023-08-12 |
mouse |
| M F La Via, A Misefari, D Venza-Teti, G Teti, A Gabrielli, I Paves. Depression of direct plaque-forming cell response in mouse spleen cell cultures by aggregated IgG2b-induced factors. Immunology letters. vol 8. issue 4. 1985-01-03. PMID:6238906. |
these observations extend previous work suggesting that igg2b-induced pfc depression may result from activation of suppressor t cells with elaboration of soluble suppressor factors. |
1985-01-03 |
2023-08-12 |
mouse |
| T Amamoto, T Okazaki, T Komurasaki, K Oguma, M Tamai, K Hanada, S Omur. Immunopharmacologic profiles of a thiol protease inhibitor, L-trans-dicyclohexyl epoxysuccinate. Japanese journal of pharmacology. vol 34. issue 3. 1984-07-09. PMID:6374218. |
the in vivo administration of ep-1 caused a depression of the plaque forming cells (pfc) for sheep red blood cell (srbc) and enhanced the delayed-type hypersensitivity (dth) for bovine serum albumin (bsa) as well as mixed lymphocytes cultures (mlc). |
1984-07-09 |
2023-08-12 |
mouse |
| N M Ali, J M Behnk. Nematospiroides dubius: factors affecting the primary response to SRBC in infected mice. Journal of helminthology. vol 57. issue 4. 1984-03-26. PMID:6366045. |
the ha and pfc response to srbc in infected animals was characterized by a severe depression of antibody to srbc on day 4 and a reduced ha peak titre during the following week. |
1984-03-26 |
2023-08-12 |
mouse |
| S Nakaike, C Tanaka, N Tomita, M Umemoto, S Otomo, H Aihar. Immunopharmacologic studies of D-penicillamine-L-cysteine disulfide. Japanese journal of pharmacology. vol 33. issue 5. 1984-01-27. PMID:6358589. |
in vivo, administration of p-c produced either enhancement or depression of plaque forming cell (pfc) response and delayed type hypersensitivity (dth) to sheep red blood cells (srbc) in low responder mice to srbc, depending on the dose of p-c. p-c restored the impaired pfc response in hydrocortisone-pretreated mice. |
1984-01-27 |
2023-08-12 |
mouse |
| S Otomo, S Nakaike, I Tsuji, C Mori, M Ohzek. Studies of D-penicillamine (3): immunomodulating effects of D-penicillamine. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. vol 77. issue 3. 1983-06-10. PMID:6820351. |
d-pa produced either enhancement or depression of the number of pfc, depending on the dose of antigenic stimulus of srbc. |
1983-06-10 |
2023-08-12 |
mouse |
| K B Franklin, A Robertso. Effects and interactions of naloxone and amphetamine on self-stimulation of the prefrontal cortex and dorsal tegmentum. Pharmacology, biochemistry, and behavior. vol 16. issue 3. 1982-07-19. PMID:7079280. |
naloxone (0.1 to 10 mg/kg) caused a dose-dependent depression of self-stimulation of the medial prefrontal cortex (pfc) lateral hypothalamus (lh) and a region in the dorsal tegmentum lateral to the central gray (dt). |
1982-07-19 |
2023-08-12 |
Not clear |
| S E Yen, J M Mansfield, R F Levine, J H Wallac. The prickly lettuce agglutinin. II. Immunobiological properties. International archives of allergy and applied immunology. vol 65. issue 4. 1981-09-15. PMID:6972920. |
similarly, 50 micrograms pla enhanced the b cell response to siii, a helper t cell-independent antigen, but higher doses did not cause significant depression of the siii-specific pfc response. |
1981-09-15 |
2023-08-12 |
mouse |
| V Souvannavong, A Ada. Opposite effects of the synthetic adjuvant N-acetyl-muramyl-L-alanyl-D-isoglutamine on the immune response in mice depending on experimental conditions. European journal of immunology. vol 10. issue 8. 1980-10-27. PMID:6995138. |
route, mdp led to an enhancement of the response; in contrast, when antigen was injected i.p., a depression of the pfc response was observed. |
1980-10-27 |
2023-08-12 |
mouse |
| M F La Via, D S La Vi. Phenol derivatives are immunodepressive in mice. Drug and chemical toxicology. vol 2. issue 1-2. 1980-09-23. PMID:548252. |
mice exposed to a compound containing three phenol derivatives by being housed in cages washed with dilute solutions of the compound, developed considerable depression of the ability to generate plaque forming cells (pfc) in response to sheep erythrocytes (srbc) in vitro after a four week exposure. |
1980-09-23 |
2023-08-11 |
mouse |
| C G Romball, R J Ulevitch, W O Weigl. Role of C3 in the regulation of a splenic PFC response in rabbits. Journal of immunology (Baltimore, Md. : 1950). vol 124. issue 1. 1980-02-28. PMID:6153091. |
c3 depletion had no effect on the first peak of pfc (appearing 5 days after injection), but resulted in depression of the second peak of pfc (day 13). |
1980-02-28 |
2023-08-12 |
human |
| C G Romball, R J Ulevitch, W O Weigl. Role of C3 in the regulation of a splenic PFC response in rabbits. Journal of immunology (Baltimore, Md. : 1950). vol 124. issue 1. 1980-02-28. PMID:6153091. |
delaying c3 depletion until after antigen localization had occurred resulted in no depression of the second peak of pfc. |
1980-02-28 |
2023-08-12 |
human |
| G E Alexander, P S Goldma. Functional development of the dorsolateral prefrontal cortex: an analysis utlizing reversible cryogenic depression. Brain research. vol 143. issue 2. 1978-05-08. PMID:415802. |
functional development of the dorsolateral prefrontal cortex: an analysis utlizing reversible cryogenic depression. |
1978-05-08 |
2023-08-11 |
monkey |
| G E Alexander, P S Goldma. Functional development of the dorsolateral prefrontal cortex: an analysis utlizing reversible cryogenic depression. Brain research. vol 143. issue 2. 1978-05-08. PMID:415802. |
cryogenic depression of prefrontal cortex at a temperature sufficient to induce 21--25% decrements in delayed-response performance in 34--36-month-old-monkeys, produced deficits of only 7--8% in 19--31-month-old and no detectable loss in younger monkeys, 9--16 months of age. |
1978-05-08 |
2023-08-11 |
monkey |