| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Chiara Melis, Genevieve Beauvais, Brian S Muntean, Maria-Daniela Cirnaru, Garrett Otrimski, Jordi Creus-Muncunill, Kirill A Martemyanov, Pedro Gonzalez-Alegre, Michelle E Ehrlic. Striatal Dopamine Induced ERK Phosphorylation Is Altered in Mouse Models of Monogenic Dystonia. Movement disorders : official journal of the Movement Disorder Society. vol 36. issue 5. 2021-05-19. PMID:33458877. |
striatal dopamine induced erk phosphorylation is altered in mouse models of monogenic dystonia. |
2021-05-19 |
2023-08-13 |
mouse |
| Kazuyuki Togo, Toshiya Ishihara, Kenji Yamamoto, Hideyuki Sawad. Older-onset levodopa-responsive parkinsonism with normal DAT-SPECT and pterin hypometabolism. BMJ case reports. vol 14. issue 5. 2021-05-14. PMID:33962918. |
gtp cyclohydrolase 1 (gch-1) deficiency, which triggers pteridine hypometabolism and normally develops in childhood, can mediate an adult-onset decrease in levodopa production and dopa-responsive dystonia (drd), with normal dopamine transporter single-photon emission computed tomography (dat-spect). |
2021-05-14 |
2023-08-13 |
Not clear |
| Marlous C M van der Weijden, Dayana Rodriguez-Contreras, Cathérine C S Delnooz, Brooks G Robinson, Alec F Condon, Michelle L Kielhold, Gilles N Stormezand, Kai Yu Ma, Claudia Dufke, John T Williams, Kim A Neve, Marina A J Tijssen, Dineke S Verbee. A Gain-of-Function Variant in Dopamine D2 Receptor and Progressive Chorea and Dystonia Phenotype. Movement disorders : official journal of the Movement Disorder Society. vol 36. issue 3. 2021-04-23. PMID:33200438. |
a gain-of-function variant in dopamine d2 receptor and progressive chorea and dystonia phenotype. |
2021-04-23 |
2023-08-13 |
Not clear |
| Marlous C M van der Weijden, Dayana Rodriguez-Contreras, Cathérine C S Delnooz, Brooks G Robinson, Alec F Condon, Michelle L Kielhold, Gilles N Stormezand, Kai Yu Ma, Claudia Dufke, John T Williams, Kim A Neve, Marina A J Tijssen, Dineke S Verbee. A Gain-of-Function Variant in Dopamine D2 Receptor and Progressive Chorea and Dystonia Phenotype. Movement disorders : official journal of the Movement Disorder Society. vol 36. issue 3. 2021-04-23. PMID:33200438. |
we describe a 4-generation dutch pedigree with a unique dominantly inherited clinical phenotype of a combined progressive chorea and cervical dystonia carrying a novel heterozygous dopamine d2 receptor (drd2) variant. |
2021-04-23 |
2023-08-13 |
Not clear |
| Ichiro Kawahata, Kohji Fukunag. Degradation of Tyrosine Hydroxylase by the Ubiquitin-Proteasome System in the Pathogenesis of Parkinson's Disease and Dopa-Responsive Dystonia. International journal of molecular sciences. vol 21. issue 11. 2021-02-12. PMID:32471089. |
previous studies revealed that expression of the gene encoding nigrostriatal tyrosine hydroxylase (th), a rate-limiting enzyme of dopamine biosynthesis, is reduced in parkinson's disease and dopa-responsive dystonia; however, the mechanism of th depletion in these disorders remains unclear. |
2021-02-12 |
2023-08-13 |
Not clear |
| Eri Hayano, Mikito Shimizu, Kousuke Baba, Munehisa Shimamura, Tomokatsu Yoshida, Hideki Mochizuk. [A case of Alexander disease presented with dystonia of lower limb and decreased dopaminergic uptake in dopamine transporter scintigraphy]. Rinsho shinkeigaku = Clinical neurology. vol 60. issue 10. 2020-11-23. PMID:32893243. |
[a case of alexander disease presented with dystonia of lower limb and decreased dopaminergic uptake in dopamine transporter scintigraphy]. |
2020-11-23 |
2023-08-13 |
Not clear |
| Ryul Kim, Beomseok Jeon, Woong-Woo Le. A Systematic Review of Treatment Outcome in Patients with Dopa-responsive Dystonia (DRD) and DRD-Plus. Movement disorders clinical practice. vol 3. issue 5. 2020-10-01. PMID:30363598. |
dopa-responsive dystonia (drd) and drd-plus are inherited metabolic disorders of the dopamine synthetic pathway that have considerable clinical, biochemical, and genetic heterogeneity. |
2020-10-01 |
2023-08-13 |
Not clear |
| Eng Wee Chua, Simon P Harger, Martin A Kenned. Metoclopramide-Induced Acute Dystonic Reactions May Be Associated With the CYP2D6 Poor Metabolizer Status and Pregnancy-Related Hormonal Changes. Frontiers in pharmacology. vol 10. 2020-10-01. PMID:31507424. |
we theorize that cyp2d6 governs the risk of metoclopramide-related acute dystonia through its role in the synthesis of serotonin, which inhibits the dopamine tone. |
2020-10-01 |
2023-08-13 |
Not clear |
| Tars. Tardive Dyskinesia. Current treatment options in neurology. vol 2. issue 3. 2020-09-30. PMID:11096748. |
tetrabenazine and reserpine are presynaptic dopamine depletors that may have considerable efficacy in td, especially tardive dystonia; however, their use is often limited by side effects. |
2020-09-30 |
2023-08-12 |
Not clear |
| Bastien Ribot, Jérome Aupy, Marie Vidailhet, Joachim Mazère, Antonio Pisani, Erwan Bezard, Dominique Guehl, Pierre Burbau. Dystonia and dopamine: From phenomenology to pathophysiology. Progress in neurobiology. vol 182. 2020-09-10. PMID:31404592. |
dystonia and dopamine: from phenomenology to pathophysiology. |
2020-09-10 |
2023-08-13 |
Not clear |
| Bastien Ribot, Jérome Aupy, Marie Vidailhet, Joachim Mazère, Antonio Pisani, Erwan Bezard, Dominique Guehl, Pierre Burbau. Dystonia and dopamine: From phenomenology to pathophysiology. Progress in neurobiology. vol 182. 2020-09-10. PMID:31404592. |
however, the link between dystonia and dopamine appears complex and remains unclear. |
2020-09-10 |
2023-08-13 |
Not clear |
| Bastien Ribot, Jérome Aupy, Marie Vidailhet, Joachim Mazère, Antonio Pisani, Erwan Bezard, Dominique Guehl, Pierre Burbau. Dystonia and dopamine: From phenomenology to pathophysiology. Progress in neurobiology. vol 182. 2020-09-10. PMID:31404592. |
because dystonia is a disorder of motor routines, we first focus on the role of dopamine and striatum in procedural learning. |
2020-09-10 |
2023-08-13 |
Not clear |
| Bastien Ribot, Jérome Aupy, Marie Vidailhet, Joachim Mazère, Antonio Pisani, Erwan Bezard, Dominique Guehl, Pierre Burbau. Dystonia and dopamine: From phenomenology to pathophysiology. Progress in neurobiology. vol 182. 2020-09-10. PMID:31404592. |
search strategy and selection criteria references for this article were identified through searches in pubmed with the search terms « dystonia », « dopamine", « striatum », « basal ganglia », « imaging data », « animal model », « procedural learning », « pathophysiology », and « plasticity » from 1998 until 2018. |
2020-09-10 |
2023-08-13 |
Not clear |
| Aakash S Shetty, Kailash P Bhatia, Anthony E Lan. Dystonia and Parkinson's disease: What is the relationship? Neurobiology of disease. vol 132. 2020-07-27. PMID:31078682. |
the response of early dystonia to the introduction of dopamine replacement therapy (levodopa, dopamine agonists) is variable; dystonia commonly occurs in pd patients following levodopa initiation. |
2020-07-27 |
2023-08-13 |
Not clear |
| Aakash S Shetty, Kailash P Bhatia, Anthony E Lan. Dystonia and Parkinson's disease: What is the relationship? Neurobiology of disease. vol 132. 2020-07-27. PMID:31078682. |
pharmacological blockade of dopamine receptors can cause both tardive dystonia and parkinsonism and these movement disorders syndromes can occur in many other neurodegenerative, genetic, toxic and metabolic diseases. |
2020-07-27 |
2023-08-13 |
Not clear |
| Ali El-Kasaby, Ameya Kasture, Florian Koban, Matej Hotka, Hafiz M M Asjad, Helmut Kubista, Michael Freissmuth, Sonja Suci. Rescue by 4-phenylbutyrate of several misfolded creatine transporter-1 variants linked to the creatine transporter deficiency syndrome. Neuropharmacology. vol 161. 2020-07-14. PMID:30885608. |
folding-deficient mutants of the dopamine transporter and of the glycine transporter-2 cause infantile/juvenile parkinsonism dystonia and hyperekplexia, respectively. |
2020-07-14 |
2023-08-13 |
human |
| Alessio Di Fonzo, Giulia Franco, Paolo Barone, Roberto Err. Parkinsonism in diseases predominantly presenting with dystonia. International review of neurobiology. vol 149. 2020-06-01. PMID:31779818. |
here, we review the diseases predominantly presenting with dystonia where parkinsonism can develop, according to their main pathophysiological mechanism including disorders of dopamine biosynthesis, neurotransmitter transporter disorders, disorder of metal metabolism (i.e., iron, copper and manganese) and other inherited dystonia-parkinsonism conditions. |
2020-06-01 |
2023-08-13 |
Not clear |
| Mohammad Moshahid Khan, Jianfeng Xiao, T J Hollingsworth, Damini Patel, Dana E Selley, Trevor L Ring, Mark S LeDou. Gnal haploinsufficiency causes genomic instability and increased sensitivity to haloperidol. Experimental neurology. vol 318. 2020-03-02. PMID:31034808. |
dopamine d2 receptor (d2r) blockers such as haloperidol are mainstays in the treatment of psychosis but may contribute to the development of secondary acute and tardive dystonia. |
2020-03-02 |
2023-08-13 |
Not clear |
| Bastien Ribot, Jérome Aupy, Marie Vidailhet, Joachim Mazère, Antonio Pisani, Erwan Bezard, Dominique Guehl, Pierre Burbau. Corrigendum to "Dystonia and dopamine: From phenomenology to pathophysiology" [Prog. Neurobiol. 182 (November) (2019), 101678, 18]. Progress in neurobiology. vol 185. 2020-02-11. PMID:31928793. |
corrigendum to "dystonia and dopamine: from phenomenology to pathophysiology" [prog. |
2020-02-11 |
2023-08-13 |
Not clear |
| Uladzislau Rudakou, Bouchra Ouled Amar Bencheikh, Jennifer A Ruskey, Lynne Krohn, Sandra B Laurent, Dan Spiegelman, Christopher Liong, Stanley Fahn, Cheryl Waters, Oury Monchi, Edward A Fon, Yves Dauvilliers, Roy N Alcalay, Nicolas Dupré, Ziv Gan-O. Common and rare GCH1 variants are associated with Parkinson's disease. Neurobiology of aging. vol 73. 2019-12-19. PMID:30314816. |
gch1 encodes the enzyme guanosine triphospahte (gtp) cyclohydrolase 1, essential for dopamine synthesis in nigrostriatal cells, and rare mutations in gch1 may lead to dopa-responsive dystonia (drd). |
2019-12-19 |
2023-08-13 |
Not clear |