Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Xiaosong He, Xin Wang, Hui Wang, Tao Wang, Fuhan Yang, Yuchen Chen, Zifei Pei, Yuting Bai, Wen Li, Zheng Wu, Gong Che. NeuroD1 Regulated Endothelial Gene Expression to Modulate Transduction of AAV-PHP.eB and Recovery Progress after Ischemic Stroke. Aging and disease. 2024-01-25. PMID:38270116. |
following the changes of signaling pathways in endothelial cells, neurod1 effectively protected bbb integrity, attenuated neuroinflammation, inhibited neuron apoptosis and rescued motor deficits after ischemic stroke. |
2024-01-25 |
2024-01-27 |
mouse |
Guangchen Xu, Ge Liu, Ziyu Wang, Yunman Li, Weirong Fan. Circular RNAs: Promising Treatment Targets and Biomarkers of Ischemic Stroke. International journal of molecular sciences. vol 25. issue 1. 2024-01-11. PMID:38203348. |
this review provides a summary of 31 circrnas involved in the pathophysiological processes of apoptosis, autophagy, inflammation, oxidative stress, and angiogenesis following ischemic stroke. |
2024-01-11 |
2024-01-13 |
Not clear |
Sungeun Chung, Yujong Yi, Irfan Ullah, Kunho Chung, Seongjun Park, Jaeyeoung Lim, Chaeyeon Kim, Seon-Hong Pyun, Minkyung Kim, Dokyoung Kim, Minhyung Lee, Taiyoun Rhim, Sang-Kyung Le. Systemic Treatment with Fas-Blocking Peptide Attenuates Apoptosis in Brain Ischemia. International journal of molecular sciences. vol 25. issue 1. 2024-01-11. PMID:38203830. |
apoptosis plays a crucial role in neuronal injury, with substantial evidence implicating fas-mediated cell death as a key factor in ischemic strokes. |
2024-01-11 |
2024-01-13 |
mouse |
Bin Sun, Jing Luo, Zhen Li, Dongfeng Chen, Qizhang Wang, Wenwen S. Muscone alleviates neuronal injury via increasing stress granules formation and reducing apoptosis in acute ischemic stroke. Experimental neurology. 2024-01-07. PMID:38185313. |
muscone alleviates neuronal injury via increasing stress granules formation and reducing apoptosis in acute ischemic stroke. |
2024-01-07 |
2024-01-10 |
rat |
Yuqian Zhang, Shenghan Gao, Shengnan Xia, Haiyan Yang, Xinyu Bao, Qingxiu Zhang, Yun X. Linarin ameliorates ischemia-reperfusion injury by the inhibition of endoplasmic reticulum stress targeting AKR1B1. Brain research bulletin. 2024-01-05. PMID:38181967. |
neuroinflammation and neuronal apoptosis mediated by endoplasmic reticulum stress are some of the important pathological mechanisms in ischemic stroke. |
2024-01-05 |
2024-01-08 |
Not clear |
Weihua Wang, Dunlin Lu, Youkui Shi, Yanqiang Wan. Exploring the Neuroprotective Effects of Lithium in Ischemic Stroke: A literature review. International journal of medical sciences. vol 21. issue 2. 2024-01-03. PMID:38169754. |
through these pathways, lithium has been shown to affect inflammation, autophagy, apoptosis, ferroptosis, excitotoxicity, and other pathological processes, thereby improving central nervous system (cns) damage caused by ischemic stroke. |
2024-01-03 |
2024-01-06 |
Not clear |
Yue Cao, Wanmei Yao, Rongrong Lu, Huan Zhao, Wenyi Wei, Xiaolei Lei, Zheng Zhang, Biwang Li. Reveal the correlation between hub hypoxia/immune-related genes and immunity and diagnosis, and the effect of SAP30 on cell apoptosis, ROS and MDA production in cerebral ischemic stroke. Aging. vol 15. 2023-12-28. PMID:38154101. |
reveal the correlation between hub hypoxia/immune-related genes and immunity and diagnosis, and the effect of sap30 on cell apoptosis, ros and mda production in cerebral ischemic stroke. |
2023-12-28 |
2023-12-31 |
Not clear |
Jie Zhou, Weiping Wang, Dong Liu, Shaofeng Xu, Xue Wang, Xinyuan Zhang, Xiaoyu Wang, Yan Li, Li Sheng, Xiaoliang Wang, Bailing X. Discovery of 2-Ethoxy-5-isobutyramido- Journal of medicinal chemistry. 2023-12-27. PMID:38150670. |
discovery of 2-ethoxy-5-isobutyramido- kv2.1 is involved in regulating neuronal excitability and neuronal cell apoptosis, and inhibiting kv2.1 is a potential strategy to prevent cell death and achieve neuroprotection in ischemic stroke. |
2023-12-27 |
2023-12-30 |
Not clear |
Caiwang Peng, Qidi Ai, Fengyan Zhao, Hengli Li, Yang Sun, Keyan Tang, Yantao Yang, Naihong Chen, Fang Li. Quercetin attenuates cerebral ischemic injury by inhibiting ferroptosis via Nrf2/HO-1 signaling pathway. European journal of pharmacology. 2023-12-20. PMID:38123006. |
ischemic stroke is a severe cerebrovascular disease in which neuronal death continually occurs through multiple forms, including apoptosis, autophagy, pyroptosis and ferroptosis. |
2023-12-20 |
2023-12-23 |
Not clear |
Hanrui Zhang, Guquan Ma, Hequn Lv, Yongjun Pen. Bibliometric Analysis of Non-coding RNAs and Ischemic Stroke: Trends, Frontiers, and Challenges. Molecular biotechnology. 2023-12-08. PMID:38064146. |
our findings indicated ncrnas has been increasingly investigated for its critical role in apoptosis, autophagy, angiogenesis, inflammation, oxidative stress, and blood-brain barrier after ischemic stroke by regulating target mrnas, extracellular secretion, target proteins, and others. |
2023-12-08 |
2023-12-17 |
Not clear |
Chujuan Liu, Hui Chen, Xi Tao, Chen Li, Aiping Li, Wen W. ALKBH5 protects against stroke by reducing endoplasmic reticulum stress-dependent inflammation injury via the STAT5/PERK/EIF2α/CHOP signaling pathway in an m Experimental neurology. 2023-12-06. PMID:38056583. |
alkbh5 protects against stroke by reducing endoplasmic reticulum stress-dependent inflammation injury via the stat5/perk/eif2α/chop signaling pathway in an m endoplasmic reticulum (er) stress causes neuroinflammation and neuronal apoptosis during ischemic stroke progression. |
2023-12-06 |
2023-12-10 |
Not clear |
Jianjiao Qi, Bin Han, Zhiyuan Wang, Lihong Jing, Xintao Tian, Jinping Su. Chuanzhitongluo inhibits neuronal apoptosis in mice with acute ischemic stroke by regulating the PI3K/AKT signaling pathway. Neuroscience. 2023-12-01. PMID:38040086. |
chuanzhitongluo inhibits neuronal apoptosis in mice with acute ischemic stroke by regulating the pi3k/akt signaling pathway. |
2023-12-01 |
2023-12-10 |
mouse |
Jianjiao Qi, Bin Han, Zhiyuan Wang, Lihong Jing, Xintao Tian, Jinping Su. Chuanzhitongluo inhibits neuronal apoptosis in mice with acute ischemic stroke by regulating the PI3K/AKT signaling pathway. Neuroscience. 2023-12-01. PMID:38040086. |
apoptosis is involved in the occurrence and development of acute ischemic stroke (ais). |
2023-12-01 |
2023-12-10 |
mouse |
Yaowen Luo, Junkai Cheng, Yihao Fu, Min Zhang, Maorong Gou, Juan Li, Xiaobing Li, Jing Bai, Yuefei Zhou, Lei Zhang, Dakuan Ga. D-allose Inhibits TLR4/PI3K/AKT Signaling to Attenuate Neuroinflammation and Neuronal Apoptosis by Inhibiting Gal-3 Following Ischemic Stroke. Biological procedures online. vol 25. issue 1. 2023-12-01. PMID:38017376. |
d-allose inhibits tlr4/pi3k/akt signaling to attenuate neuroinflammation and neuronal apoptosis by inhibiting gal-3 following ischemic stroke. |
2023-12-01 |
2023-12-07 |
Not clear |
Yaowen Luo, Junkai Cheng, Yihao Fu, Min Zhang, Maorong Gou, Juan Li, Xiaobing Li, Jing Bai, Yuefei Zhou, Lei Zhang, Dakuan Ga. D-allose Inhibits TLR4/PI3K/AKT Signaling to Attenuate Neuroinflammation and Neuronal Apoptosis by Inhibiting Gal-3 Following Ischemic Stroke. Biological procedures online. vol 25. issue 1. 2023-12-01. PMID:38017376. |
d-allose inhibits tlr4/pi3k/akt signaling to attenuate neuroinflammation and neuronal apoptosis by inhibiting gal-3 following ischemic stroke. |
2023-11-28 |
2023-12-07 |
Not clear |
Wei Ma, Jinwei Yang, Jinfen Zhang, Rui He, Yi Luo, Chunyan Li, Feng Zhao, Fengping Tao, Jinjin Fan, Luwei Yin, Kewei Zhu, Shourui Niu, Liyan L. Cerebral protective effect of in situ and remote ischemic postconditioning on ischemic stroke rat via the TGFβ1-Smad2/3 signaling pathway. Brain research. 2023-11-25. PMID:38006988. |
we showed that application of both types of ischemic postconditioning had cerebral protective effects for the ischemic stroke rats, that included effective reduction in the volume of cerebral infarction, alleviation of apoptosis and inflammation in the ischemic penumbra, and promotion of recovery of neurological function. |
2023-11-25 |
2023-11-28 |
rat |
Tai Zhou, Lei Zhang, Li He, Yan Lan, Lei Ding, Li Li, Zhongcheng Wan. GSK-126 Attenuates Cell Apoptosis in Ischemic Brain Injury by Modulating the EZH2-H3K27me3-Bcl2l1 Axis. Molecular neurobiology. 2023-11-22. PMID:37989985. |
whether epigenetic modifications participate in the cell apoptosis after ischemic stroke remains unclear. |
2023-11-22 |
2023-11-29 |
Not clear |
Shan Meng, Hui Cao, Yichen Huang, Ziyu Shi, Jiaying Li, Yana Wang, Yue Zhang, Shuning Chen, Hong Shi, Yanqin Ga. ASK1-K716R reduces neuroinflammation and white matter injury via preserving blood-brain barrier integrity after traumatic brain injury. Journal of neuroinflammation. vol 20. issue 1. 2023-10-26. PMID:37875988. |
apoptosis signal-regulating kinase 1 (ask1), a key player in various central nervous system (cns) diseases, has garnered interest for its potential neuroprotective effects against ischemic stroke and epilepsy when deleted. |
2023-10-26 |
2023-11-08 |
mouse |
Dunpeng Cai, Mikayla Fraunfelder, Ken Fujise, Shi-You Che. ADAR1 exacerbates ischemic brain injury via astrocyte-mediated neuron apoptosis. Redox biology. vol 67. 2023-10-06. PMID:37801857. |
these results indicated that adar1 is a novel regulator promoting the proliferation of the activated astrocytes following ischemic stroke, which produce various inflammatory cytokines, leading to neuron apoptosis and worsened ischemic stroke outcome. |
2023-10-06 |
2023-10-15 |
mouse |
Khan Haroon, Huitong Ruan, Haoran Zheng, Shengju Wu, Ze Liu, Xiaojing Shi, Yaohui Tang, Guo-Yuan Yang, Zhijun Zhan. Bio-clickable, small extracellular vesicles-COCKTAIL therapy for ischemic stroke. Journal of controlled release : official journal of the Controlled Release Society. 2023-10-04. PMID:37793483. |
in the in vitro ischemic stroke model of oxygen-glucose deprivation, the sevs-cocktail exhibited remarkable potential against reactive oxygen species and cellular apoptosis. |
2023-10-04 |
2023-10-07 |
Not clear |