| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xiuling Tang, Tao Yan, Saiying Wang, Qingqing Liu, Qi Yang, Yongqiang Zhang, Yujiao Li, Yumei Wu, Shuibing Liu, Yulong Ma, Le Yan. Treatment with β-sitosterol ameliorates the effects of cerebral ischemia/reperfusion injury by suppressing cholesterol overload, endoplasmic reticulum stress, and apoptosis. Neural regeneration research. vol 19. issue 3. 2023-09-18. PMID:37721296. |
here we found that, in a mouse model of ischemic stroke induced by middle cerebral artery occlusion, β-sitosterol reduced the volume of cerebral infarction and brain edema, reduced neuronal apoptosis in brain tissue, and alleviated neurological dysfunction; moreover, β-sitosterol increased the activity of oxygen- and glucose-deprived cerebral cortex neurons and reduced apoptosis. |
2023-09-18 |
2023-10-07 |
mouse |
| Li-Qun Lu, Nian-Sheng Li, Ming-Rui Li, Jiao-Yang Peng, Li-Jing Tang, Xiu-Ju Luo, Jun Pen. DL-3-n-butylphthalide improves the endothelium-dependent vasodilation in high-fat diet-fed ApoE European journal of pharmacology. 2023-08-03. PMID:37536623. |
dl-3-n-butylphthalide improves the endothelium-dependent vasodilation in high-fat diet-fed apoe impaired endothelium-dependent vasodilation in atherosclerosis is a high-risk factor for myocardial infarction and ischemic stroke, and inflammation, necroptosis and apoptosis contribute to endothelial dysfunction in atherosclerosis. |
2023-08-03 |
2023-08-14 |
Not clear |
| Ya-Shuo Feng, Yi Wu, Nian-Hong Wan. [Research progress of the impacts of acupuncture on programmed cell death in treatment of ischemic stroke]. Zhen ci yan jiu = Acupuncture research. vol 48. issue 7. 2023-07-31. PMID:37518967. |
autophagy, apoptosis, pyroptosis, necroptosis and ferroptosis) for the pathological mechanism of ischemic stroke. |
2023-07-31 |
2023-08-14 |
Not clear |
| Ya-Shuo Feng, Yi Wu, Nian-Hong Wan. [Research progress of the impacts of acupuncture on programmed cell death in treatment of ischemic stroke]. Zhen ci yan jiu = Acupuncture research. vol 48. issue 7. 2023-07-31. PMID:37518967. |
the researches in recent years have shown that acupuncture plays its neuroprotective role on ischemic stroke by modulation of autophagy, apoptosis, pyroptosis, necroptosis and ferroptosis of neurons. |
2023-07-31 |
2023-08-14 |
Not clear |
| Si-Yi Xu, Jun-Qiu Jia, Min Sun, Xin-Yu Bao, Sheng-Nan Xia, Shu Shu, Pin-Yi Liu, Sen-Lin Ji, Lei Ye, Xiang Cao, Yun X. QHRD106 ameliorates ischemic stroke injury as a long-acting tissue kallikrein preparation. iScience. vol 26. issue 7. 2023-07-27. PMID:37496671. |
mechanistically, qhrd106 reduced high-mobility group box 1 (hmgb1)-induced apoptosis and inflammation after ischemic stroke |
2023-07-27 |
2023-08-14 |
Not clear |
| Aifen Liu, Jingyan Hu, Tzu-Shao Yeh, Chengniu Wang, Jilong Tang, Xiaohong Huang, Bin Chen, Liexiang Huangfu, Weili Yu, Lei Zhan. Neuroprotective Strategies for Stroke by Natural Products: Advances and Perspectives. Current neuropharmacology. 2023-07-17. PMID:37458258. |
then we propose the comprehensive neuroprotective mechanism of nps in cerebral ischemic stroke, which involves complex cascade processes of oxidative stress, mitochondrial damage, apoptosis or ferroptosis-related cell death, inflammatory response, and disruption of the blood- brain barrier (bbb). |
2023-07-17 |
2023-08-14 |
Not clear |
| Xia Liu, Qinlian Ye, Zhengzheng Huang, Xiuping Li, Liping Zhang, Xuan Liu, Yun-Cheng Wu, Ulf Brockmeier, Dirk M Hermann, Ya-Chao Wang, Lijie Re. BAG3 Overexpression Attenuates Ischemic Stroke Injury by Activating Autophagy and Inhibiting Apoptosis. Stroke. 2023-06-28. PMID:37377010. |
bag3 overexpression attenuates ischemic stroke injury by activating autophagy and inhibiting apoptosis. |
2023-06-28 |
2023-08-14 |
mouse |
| Gui-Ling Wang, Shu-Ying Xu, He-Qun Lv, Chao Zhang, Yong-Jun Pen. Electroacupuncture Inhibits Ferroptosis Induced by Cerebral Ischemia-reperfusion. Current neurovascular research. 2023-06-26. PMID:37357521. |
studies have shown that ea can relieve brain damage after ischemic stroke by inhibiting programmed cell death (pcd), such as apoptosis, necroptosis, and autophagy. |
2023-06-26 |
2023-08-14 |
Not clear |
| Yuxin Zhang, Huijuan Lou, Jing Lu, Xiaolei Tang, Tingting Pang, Siyuan Lei, Deyu Cong, Yufeng Wang, Liwei Su. Scalp acupuncture alleviates cerebral ischemic stroke-induced motor dysfunction in rats via regulating endoplasmic reticulum stress and ER-phagy. Scientific reports. vol 13. issue 1. 2023-06-21. PMID:37344501. |
in conclusion, the present study showed that scalp acupuncture of vertex middle line and anterior oblique line of vertex temple may alleviate cerebral ischemic stroke by inhibiting er stress-accelerated apoptosis. |
2023-06-21 |
2023-08-14 |
rat |
| Pin Zhao, Jiapo Zhang, JianKe Kuai, Liya Li, Xuying Li, Namin Feng, Hailiang Du, Chen Li, Qiang Wang, Bin Den. TAT-PEP Alleviated Cognitive Impairment by Alleviating Neuronal Mitochondria Damage and Apoptosis After Cerebral Ischemic Reperfusion Injury. Molecular neurobiology. 2023-06-19. PMID:37335462. |
this study also suggests that tat-pep may be a potent neuroprotectant with therapeutic potential for stroke by reducing neuronal oxidative stress, mitochondrial damage, degeneration and apoptosis in ischemic stroke. |
2023-06-19 |
2023-08-14 |
Not clear |
| Donghai Li, Tianpeng He, Yue Zhang, Junru Liu, Haiyu Zhao, Dongliang Wang, Quanchao Wang, Yuan Yuan, Shengxiang Zhan. Melatonin regulates microglial polarization and protects against ischemic stroke-induced brain injury in mice. Experimental neurology. 2023-06-10. PMID:37301531. |
our results demonstrated that melatonin treatment reduced the infarct volume, prevented neuronal loss and apoptosis, and improved neurological deficits after ischemic stroke. |
2023-06-10 |
2023-08-14 |
mouse |
| Mengru Zhang, Jianjun Wang, Jinfang Li, Fanxin Kong, Songjun Li. miR-101-3p improves neuronal morphology and attenuates neuronal apoptosis in ischemic stroke in young mice by downregulating HDAC9. Translational neuroscience. vol 14. issue 1. 2023-05-30. PMID:37250142. |
mir-101-3p improves neuronal morphology and attenuates neuronal apoptosis in ischemic stroke in young mice by downregulating hdac9. |
2023-05-30 |
2023-08-14 |
mouse |
| Qian Suo, Lidong Deng, Tingting Chen, Shengju Wu, Lin Qi, Ze Liu, Tingting He, Heng-Li Tian, Wanlu Li, Yaohui Tang, Guo-Yuan Yang, Zhijun Zhan. Optogenetic Activation of Astrocytes Reduces Blood-Brain Barrier Disruption via IL-10 In Stroke. Aging and disease. 2023-05-17. PMID:37196130. |
we found for the first time that interleukin-10 derived from optogenetic-activated astrocytes protected blood-brain barrier integrity by decreasing the activity of matrix metallopeptidase 2 and attenuated neuronal apoptosis, which provided a novel therapeutic approach and target in the acute stage of ischemic stroke. |
2023-05-17 |
2023-08-14 |
rat |
| Kongwei Guo, Yanxing Shang, Zhao Wang, Yu Li, Jinliang Chen, Baofeng Zhu, Dongmei Zhang, Jianrong Che. BRG1 alleviates microglial activation by promoting the KEAP1-NRF2/HO-1 signaling pathway and minimizing oxidative damage in cerebral ischemia-reperfusion. International immunopharmacology. vol 119. 2023-05-12. PMID:37172425. |
brg1 is a key factor in the process of apoptosis and oxidative damage; however, its role in the pathophysiology of ischemic stroke is unclear. |
2023-05-12 |
2023-08-14 |
mouse |
| Ni-Na Song, Ying Zhao, Chuang Sun, Jun Zhang, Guang-Jun Lin, Xiao-Wei Yin, Chun-Ye M. DUSP10 alleviates ischemic stroke-induced neuronal damage by restricting p38/JNK pathway. Behavioural brain research. 2023-05-10. PMID:37164190. |
neuronal apoptosis is considered one of the hallmarks of ischemic stroke. |
2023-05-10 |
2023-08-14 |
mouse |
| Yang You, Jianpei Xu, Yipu Liu, Haichun Li, Laozhi Xie, Chuchu Ma, Yinzhe Sun, Shiqiang Tong, Kaifan Liang, Songlei Zhou, Fenfen Ma, Qingxiang Song, Wenze Xiao, Kaikai Fu, Chengxiang Dai, Suke Li, Jigang Lei, Qiyong Mei, Xiaoling Gao, Jun Che. Tailored Apoptotic Vesicle Delivery Platform for Inflammatory Regulation and Tissue Repair to Ameliorate Ischemic Stroke. ACS nano. 2023-04-26. PMID:37099675. |
this work presents a platform architecture that integrates apoptosis induction, drug loading, and functionalized proteome regulation, followed by targeting modification, enabling the creation of an apoptotic vesicle delivery system to treat ischemic stroke. |
2023-04-26 |
2023-08-14 |
Not clear |
| Shenghua Lin, Xin Liu, Aonan Sun, Huiliang Liang, Zhen Li, Suyan Ye, Honglin Ma, Wei Fan, Chuanlin Shen, Meng Jin, Qiuxia H. Qilong capsule alleviates ponatinib-induced ischemic stroke in a zebrafish model by regulating coagulation, inflammation and apoptosis. Journal of ethnopharmacology. 2023-04-22. PMID:37086871. |
qilong capsule alleviates ponatinib-induced ischemic stroke in a zebrafish model by regulating coagulation, inflammation and apoptosis. |
2023-04-22 |
2023-08-14 |
zebrafish |
| Fang-Fang Zhang, Liang Zhang, Lin Zhao, Yu Lu, Xin Dong, Yan-Qi Liu, Yu Li, Shuang Guo, Si-Yuan Zheng, Ying Xiao, Yu-Zhu Jian. The circular RNA Neural regeneration research. vol 18. issue 10. 2023-04-14. PMID:37056143. |
taken together, these findings demonstrate the mechanism by which circrap1b inhibits neuronal apoptosis in acute ischemic stroke. |
2023-04-14 |
2023-08-14 |
mouse |
| Lisha Chang, Wan Zhang, Songxin Shi, Yanbo Peng, Dali Wang, Li Zhang, Jiang Zhan. Retraction Note: microRNA-195 attenuates neuronal apoptosis in rats with ischemic stroke through inhibiting KLF5-mediated activation of the JNK signaling pathway. Molecular medicine (Cambridge, Mass.). vol 29. issue 1. 2023-04-13. PMID:37055736. |
retraction note: microrna-195 attenuates neuronal apoptosis in rats with ischemic stroke through inhibiting klf5-mediated activation of the jnk signaling pathway. |
2023-04-13 |
2023-08-14 |
rat |
| Shakiba Azami, Fatemeh Forouzanfa. Potential role of Nigella Sativa and its Constituent (Thymoquinone) in Ischemic Stroke. Current molecular medicine. 2023-04-11. PMID:37038292. |
ischemic stroke is a complex pathological process involving a series of mechanisms such as ros accumulation, ca2 + overload, inflammation, and apoptosis. |
2023-04-11 |
2023-08-14 |
Not clear |