| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Melissa Asher, Juao-Guilherme Rosa, Marija Cvetanovi. Mood alterations in mouse models of Spinocerebellar Ataxia type 1. Scientific reports. vol 11. issue 1. 2021-08-10. PMID:33436887. |
spinocerebellar ataxia type 1 (sca1) is a fatal neurodegenerative disease caused by abnormal expansion of glutamine-encoding cag repeats in the ataxin-1 (atxn1) gene. |
2021-08-10 |
2023-08-13 |
mouse |
| Carrie Sheeler, Juao-Guilherme Rosa, Ella Borgenheimer, Aaron Mellesmoen, Orion Rainwater, Marija Cvetanovi. Post-symptomatic Delivery of Brain-Derived Neurotrophic Factor (BDNF) Ameliorates Spinocerebellar Ataxia Type 1 (SCA1) Pathogenesis. Cerebellum (London, England). vol 20. issue 3. 2021-07-31. PMID:33394333. |
spinocerebellar ataxia type 1 (sca1) is a fatal neurodegenerative disease caused by an abnormal expansion of cag repeats in the ataxin1 (atxn1) gene. |
2021-07-31 |
2023-08-13 |
mouse |
| Jing Fang, Yanlin Wang, Zhuoya Wang, Huifang Sun, Qi Zhang, Jing Yang, Yutao Liu, Han Liu, Changhe Shi, Yuming Xu, Xinzhong Zhang, Quancheng Ka. Generation of induced pluripotent stem cell line (ZZUi0026-A) from a patient with spinocerebellar ataxia type 3. Stem cell research. vol 53. 2021-06-30. PMID:34087977. |
spinocerebellar ataxia type 3 (sca3) is a progressive neurodegenerative disease caused by cag repeat expansion of the atxn3 gene encoding ataxin-3 protein and is mainly manifested by motor symptoms such as ataxia and non-motor symptoms such as cognitive dysfunction. |
2021-06-30 |
2023-08-13 |
Not clear |
| Martin-Paul Agbaga, Megan A Stiles, Richard S Brush, Michael T Sullivan, Adeline Machalinski, Kenneth L Jones, Robert E Anderson, David M Sherr. The Elovl4 Spinocerebellar Ataxia-34 Mutation 736T>G (p.W246G) Impairs Retinal Function in the Absence of Photoreceptor Degeneration. Molecular neurobiology. vol 57. issue 11. 2021-06-29. PMID:32780351. |
mutations in the elovl4 gene cause several distinct neurodegenerative diseases including stargardt-like macular dystrophy (stgd3), spinocerebellar ataxia 34 (sca34), and a neuro-ichthyotic syndrome with severe seizures and spasticity, as well as erythrokeratitis variabilis (ekv), a skin disorder. |
2021-06-29 |
2023-08-13 |
human |
| Lang He, Huifang Zhao, Shuai Li, Xiaobo Han, Zhao Chen, Chunrong Wang, Chao Tian, Feng Tang, Rongqi Huang, Zuoxian Lin, Zhiyuan Li, Beisha Tang, Hong Jian. Generation of induced pluripotent stem cell line (CSUXHi002-A) from a patient with spinocerebellar ataxia type 1. Stem cell research. vol 45. 2021-06-21. PMID:32335388. |
spinocerebellar ataxia type 1 (sca1) is a hereditary neurodegenerative disease caused by cag repeated expansion in atxn1 gene. |
2021-06-21 |
2023-08-13 |
Not clear |
| Agata Ciolak, Wlodzimierz J Krzyzosiak, Emilia Kozlowska, Agnieszka Fisze. Generation of human iPS cell line IBCHi002-A from spinocerebellar ataxia type 3/Machado-Joseph disease patient's fibroblasts. Stem cell research. vol 45. 2021-06-21. PMID:32361312. |
spinocerebellar ataxia type 3 (sca3), also known as machado-joseph disease (mjd), is autosomal-dominant neurodegenerative disease caused by an expansion of polyglutamine-encoding cag repeats in the atxn3 gene. |
2021-06-21 |
2023-08-13 |
human |
| Taro Ishiguro, Yoshitaka Nagai, Kinya Ishikaw. Insight Into Spinocerebellar Ataxia Type 31 (SCA31) From Frontiers in neuroscience. vol 15. 2021-06-12. PMID:34113230. |
insight into spinocerebellar ataxia type 31 (sca31) from spinocerebellar ataxia type 31 (sca31) is a progressive neurodegenerative disease characterized by degeneration of purkinje cells in the cerebellum. |
2021-06-12 |
2023-08-13 |
Not clear |
| Zheng-Cai Xia, Zhen-Hua Liu, Xiao-Xia Zhou, Zhen Liu, Jun-Ling Wang, Zheng-Mao Hu, Jie-Qiong Tan, Lu Shen, Hong Jiang, Bei-Sha Tang, Li-Fang Le. Mutation analysis of CAPN1 in Chinese populations with spastic paraplegia and related neurodegenerative diseases. Journal of the neurological sciences. vol 411. 2021-05-14. PMID:31982778. |
to investigate the role of capn1 in spastic paraplegia and other neurodegenerative diseases, including spinocerebellar ataxia (sca), early-onset parkinson's disease (eopd), and amyotrophic lateral sclerosis (als) we conducted a mutation analysis of capn1 in a cohort of chinese patients with spg, sca, eopd, and als. |
2021-05-14 |
2023-08-13 |
Not clear |
| Maria do Carmo Cost. Recent therapeutic prospects for Machado-Joseph disease. Current opinion in neurology. vol 33. issue 4. 2021-05-03. PMID:32657894. |
machado-joseph disease (mjd), also known as spinocerebellar ataxia type 3 (sca3), is a fatal, dominantly inherited, neurodegenerative disease caused by expansion of a cag repeat in the coding region of the atxn3 gene. |
2021-05-03 |
2023-08-13 |
Not clear |
| Pablo Andrei Appelt, Kristin Comella, Luciane Aparecida Pascucci Sande de Souza, Gustavo José Luvizutt. Effect of stem cell treatment on functional recovery of spinocerebellar ataxia: systematic review and meta-analysis. Cerebellum & ataxias. vol 8. issue 1. 2021-02-28. PMID:33632326. |
spinocerebellar ataxia is a hereditary neurodegenerative disease characterized by changes in balance, locomotion and motor coordination. |
2021-02-28 |
2023-08-13 |
Not clear |
| Alexander S Brown, Pratap Meera, Gabe Quinones, Jessica Magri, Thomas S Otis, Stefan M Pulst, Anthony E Or. Receptor protein tyrosine phosphatases control Purkinje neuron firing. Cell cycle (Georgetown, Tex.). vol 19. issue 2. 2021-01-29. PMID:31876231. |
spinocerebellar ataxias (sca) are a genetically heterogeneous family of cerebellar neurodegenerative diseases characterized by abnormal firing of purkinje neurons and degeneration. |
2021-01-29 |
2023-08-13 |
Not clear |
| Brennon O'Callaghan, Bente Hofstra, Hillary P Handler, Holly B Kordasiewicz, Tracy Cole, Lisa Duvick, Jillian Friedrich, Orion Rainwater, Praseuth Yang, Michael Benneyworth, Tessa Nichols-Meade, Wesley Heal, Rachel Ter Haar, Christine Henzler, Harry T Or. Antisense Oligonucleotide Therapeutic Approach for Suppression of Ataxin-1 Expression: A Safety Assessment. Molecular therapy. Nucleic acids. vol 21. 2021-01-13. PMID:32818920. |
spinocerebellar ataxia type 1 (sca1) is a lethal, autosomal dominant neurodegenerative disease caused by a polyglutamine expansion in the ataxin-1 (atxn1) protein. |
2021-01-13 |
2023-08-13 |
Not clear |
| Yingfeng Tu, Xiaoling Li, Xuefei Zhu, Xiaokang Liu, Caixia Guo, Da Jia, Tie-Shan Tan. Determining the Fate of Neurons in SCA3: ATX3, a Rising Decision Maker in Response to DNA Stresses and Beyond. Frontiers in cell and developmental biology. vol 8. 2021-01-12. PMID:33425926. |
dna damage response (ddr) and apoptosis are reported to be involved in the pathogenesis of many neurodegenerative diseases including polyglutamine (polyq) disorders, such as spinocerebellar ataxia type 3 (sca3) and huntington's disease (hd). |
2021-01-12 |
2023-08-13 |
Not clear |
| Melissa Asher, Juao-Guilherme Rosa, Orion Rainwater, Lisa Duvick, Michael Bennyworth, Ruo-Yah Lai, Sheng-Han Kuo, Marija Cvetanovi. Cerebellar contribution to the cognitive alterations in SCA1: evidence from mouse models. Human molecular genetics. vol 29. issue 1. 2020-12-21. PMID:31696233. |
spinocerebellar ataxia type 1 (sca1) is a fatal neurodegenerative disease caused by abnormal expansion of glutamine (q) encoding cag repeats in the gene ataxin-1 (atxn1). |
2020-12-21 |
2023-08-13 |
mouse |
| Douglas J Marcotte, Kerri A Spilker, Dingyi Wen, Thomas Hesson, Thomas A Patterson, P Rajesh Kumar, Jayanth V Chodaparambi. The crystal structure of the catalytic domain of tau tubulin kinase 2 in complex with a small-molecule inhibitor. Acta crystallographica. Section F, Structural biology communications. vol 76. issue Pt 3. 2020-12-01. PMID:32133995. |
inhibition of ttbk1 reduces the levels of nft formation involved in neurodegenerative diseases such as ad, whereas inhibition of ttbk2 may lead to the movement disorder spinocerebellar ataxia type 11 (sca11). |
2020-12-01 |
2023-08-13 |
human |
| Giusy Olivito, L Siciliano, S Clausi, M Lupo, S Romano, M Masciullo, M Molinari, M Cercignani, M Bozzali, M Leggi. Functional Changes of Mentalizing Network in SCA2 Patients: Novel Insights into Understanding the Social Cerebellum. Cerebellum (London, England). vol 19. issue 2. 2020-11-23. PMID:31925668. |
to this aim, patients affected by spinocerebellar ataxia type 2 (sca2), a neurodegenerative disease specifically affecting regions of the cerebellar cortex, and age-matched healthy subjects have been enrolled. |
2020-11-23 |
2023-08-13 |
human |
| Filip Tichanek, Martina Salomova, Jan Jedlicka, Jitka Kuncova, Pavel Pitule, Tereza Macanova, Zuzana Petrankova, Zdenek Tuma, Jan Cendeli. Hippocampal mitochondrial dysfunction and psychiatric-relevant behavioral deficits in spinocerebellar ataxia 1 mouse model. Scientific reports. vol 10. issue 1. 2020-11-23. PMID:32214165. |
spinocerebellar ataxia 1 (sca1) is a devastating neurodegenerative disease associated with cerebellar degeneration and motor deficits. |
2020-11-23 |
2023-08-13 |
mouse |
| S Mazdak Abulnaga, Zhen Yang, Aaron Carass, Kalyani Kansal, Bruno M Jedynak, Chiadi U Onyike, Sarah H Ying, Jerry L Princ. A toolbox to visually explore cerebellar shape changes in cerebellar disease and dysfunction. Proceedings of SPIE--the International Society for Optical Engineering. vol 9785. 2020-10-01. PMID:28479655. |
the spinocerebellar ataxias are a group of neurodegenerative diseases that cause regional atrophy in the cerebellum, yielding distinct motor and cognitive problems. |
2020-10-01 |
2023-08-13 |
human |
| Norlinah Mohamed Ibrahim, Yue Hui Lau, Noorasyikin Ariffin, Siti Hajar Md Desa, Elena Azizan, Long Kha Chin, Shahrul Azmin Md Rani, Yusnita Yakob, Santhi Datuk Puvanarajah, Bart van de Warrenbur. Frequency of Spinocerebellar Ataxia type 1, 2, 3,6 and 7 and clinical profile of Spinocerebellar Ataxia type 3 in Malaysia. Cerebellum & ataxias. vol 7. 2020-09-28. PMID:32922823. |
spinocerebellar ataxias (sca) are highly heterogenous group of neurodegenerative diseases causing progressive cerebellar dysfunction. |
2020-09-28 |
2023-08-13 |
Not clear |
| Jun Young Park, Kwangsic Joo, Se Joon Wo. Ophthalmic Manifestations and Genetics of the Polyglutamine Autosomal Dominant Spinocerebellar Ataxias: A Review. Frontiers in neuroscience. vol 14. 2020-09-28. PMID:32973440. |
spinocerebellar ataxia (sca) is a part of the cerebellar neurodegenerative disease group that is diverse in genetics and phenotypes. |
2020-09-28 |
2023-08-13 |
Not clear |