| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sharan Paul, Warunee Dansithong, Karla P Figueroa, Daniel R Scoles, Stefan M Puls. Staufen1 links RNA stress granules and autophagy in a model of neurodegeneration. Nature communications. vol 9. issue 1. 2018-12-19. PMID:30194296. |
spinocerebellar ataxia type 2 (sca2) is a neurodegenerative disease caused by expansion of polyglutamine tract in the atxn2 protein. |
2018-12-19 |
2023-08-13 |
mouse |
| Arnulf H Koeppe. The neuropathology of the adult cerebellum. Handbook of clinical neurology. vol 154. 2018-09-28. PMID:29903436. |
the cerebellum is a prominent target of several sporadic and hereditary neurodegenerative diseases, including multiple system atrophy, spinocerebellar ataxia, and friedreich ataxia. |
2018-09-28 |
2023-08-13 |
Not clear |
| G Olivito, M Lupo, C Iacobacci, S Clausi, S Romano, M Masciullo, M Molinari, M Cercignani, M Bozzali, M Leggi. Structural cerebellar correlates of cognitive functions in spinocerebellar ataxia type 2. Journal of neurology. vol 265. issue 3. 2018-08-23. PMID:29356974. |
spinocerebellar ataxia type 2 (sca2) is an autosomal dominant neurodegenerative disease involving the cerebellum and characterized by a typical motor syndrome. |
2018-08-23 |
2023-08-13 |
Not clear |
| Adriana Moro, Renato P Munhoz, Mariana Moscovich, Walter O Arruda, Salmo Raskin, Laura Silveira-Moriyama, Tetsuo Ashizawa, Hélio A G Teiv. Nonmotor Symptoms in Patients with Spinocerebellar Ataxia Type 10. Cerebellum (London, England). vol 16. issue 5-6. 2018-07-30. PMID:28589261. |
nonmotor symptoms (nms) have been described in several neurodegenerative diseases but have not been systematically evaluated in spinocerebellar ataxia type 10 (sca10). |
2018-07-30 |
2023-08-13 |
human |
| Jeanne Hsieh, Jen-Wei Liu, Horng-Jyh Harn, Kuo-Wei Hsueh, Karthyayani Rajamani, Yu-Chen Deng, Chih-Min Chia, Woei-Cheang Shyu, Shinn-Zong Lin, Tzyy-Wen Chio. Human Olfactory Ensheathing Cell Transplantation Improves Motor Function in a Mouse Model of Type 3 Spinocerebellar Ataxia. Cell transplantation. vol 26. issue 10. 2018-07-19. PMID:29251109. |
spinocerebellar ataxia (sca) is a progressive neurodegenerative disease that affects the cerebellum and spinal cord. |
2018-07-19 |
2023-08-13 |
mouse |
| G Olivito, M Lupo, C Iacobacci, S Clausi, S Romano, M Masciullo, M Molinari, M Cercignani, M Bozzali, M Leggi. Microstructural MRI Basis of the Cognitive Functions in Patients with Spinocerebellar Ataxia Type 2. Neuroscience. vol 366. 2018-06-29. PMID:29031602. |
spinocerebellar ataxia type 2 (sca2) is an autosomal dominant neurodegenerative disease involving the cerebellum. |
2018-06-29 |
2023-08-13 |
Not clear |
| Wenhui Qu, Andrea Johnson, Joo Hyun Kim, Abigail Lukowicz, Daniel Svedberg, Marija Cvetanovi. Inhibition of colony-stimulating factor 1 receptor early in disease ameliorates motor deficits in SCA1 mice. Journal of neuroinflammation. vol 14. issue 1. 2018-03-26. PMID:28545543. |
polyglutamine (polyq) expansion in the protein ataxin-1 (atxn1) causes spinocerebellar ataxia type 1 (sca1), a fatal dominantly inherited neurodegenerative disease characterized by motor deficits, cerebellar neurodegeneration, and gliosis. |
2018-03-26 |
2023-08-13 |
mouse |
| Austin Ferro, Emily Carbone, Evan Marzouk, Asher Siegel, Donna Nguyen, Kailen Polley, Jessilyn Hartman, Kimberley Frederick, Stephen Ives, Sarita Lagalwa. Treating SCA1 Mice with Water-Soluble Compounds to Non-Specifically Boost Mitochondrial Function. Journal of visualized experiments : JoVE. issue 119. 2018-01-29. PMID:28190022. |
mitochondrial dysfunction plays a significant role in the aging process and in neurodegenerative diseases including several hereditary spinocerebellar ataxias and other movement disorders marked by progressive degeneration of the cerebellum. |
2018-01-29 |
2023-08-13 |
mouse |
| Debasmita Tripathy, Beatrice Vignoli, Nandini Ramesh, Maria Jose Polanco, Marie Coutelier, Christopher D Stephen, Marco Canossa, Marie-Lorraine Monin, Pascale Aeschlimann, Shannon Turberville, Daniel Aeschlimann, Jeremy D Schmahmann, Marios Hadjivassiliou, Alexandra Durr, Udai B Pandey, Maria Pennuto, Manuela Bass. Mutations in TGM6 induce the unfolded protein response in SCA35. Human molecular genetics. vol 26. issue 19. 2018-01-23. PMID:28934387. |
spinocerebellar ataxia type 35 (sca35) is a rare autosomal-dominant neurodegenerative disease caused by mutations in the tgm6 gene, which codes for transglutaminase 6 (tg6). |
2018-01-23 |
2023-08-13 |
drosophila_melanogaster |
| Lance T Pflieger, Warunee Dansithong, Sharan Paul, Daniel R Scoles, Karla P Figueroa, Pratap Meera, Thomas S Otis, Julio C Facelli, Stefan M Puls. Gene co-expression network analysis for identifying modules and functionally enriched pathways in SCA2. Human molecular genetics. vol 26. issue 16. 2018-01-17. PMID:28525545. |
spinocerebellar ataxia type 2 (sca2) is an autosomal dominant neurodegenerative disease caused by cag repeat expansion in the atxn2 gene. |
2018-01-17 |
2023-08-13 |
mouse |
| Yu Miyazaki, Xiaofei Du, Shin-Ichi Muramatsu, Christopher M Gome. An miRNA-mediated therapy for SCA6 blocks IRES-driven translation of the CACNA1A second cistron. Science translational medicine. vol 8. issue 347. 2017-12-07. PMID:27412786. |
spinocerebellar ataxia type 6 (sca6) is a dominantly inherited neurodegenerative disease characterized by slowly progressive ataxia and purkinje cell degeneration. |
2017-12-07 |
2023-08-13 |
mouse |
| Amanda G Mason, Renee M Garza, Mark A McCormick, Bhumil Patel, Brian K Kennedy, Lorraine Pillus, Albert R La Spad. The replicative lifespan-extending deletion of SGF73 results in altered ribosomal gene expression in yeast. Aging cell. vol 16. issue 4. 2017-12-01. PMID:28568901. |
sgf73, a core component of saga, is the yeast orthologue of ataxin-7, which undergoes cag-polyglutamine repeat expansion leading to the human neurodegenerative disease spinocerebellar ataxia type 7 (sca7). |
2017-12-01 |
2023-08-13 |
human |
| Susanne K Hansen, Tina C Stummann, Helena Borland, Lis F Hasholt, Zeynep Tümer, Jørgen E Nielsen, Mikkel A Rasmussen, Troels T Nielsen, Justus C A Daechsel, Karina Fog, Poul Hytte. Induced pluripotent stem cell - derived neurons for the study of spinocerebellar ataxia type 3. Stem cell research. vol 17. issue 2. 2017-11-22. PMID:27596958. |
the neurodegenerative disease spinocerebellar ataxia type 3 (sca3) is caused by a cag-repeat expansion in the atxn3 gene. |
2017-11-22 |
2023-08-13 |
human |
| Bing-Wen Soong, Shih-Han Syu, Cheng-Hao Wen, Hui-Wen Ko, Mei-Ling Wu, Patrick C H Hsieh, Shiaw-Min Hwang, Huai-En L. Generation of induced pluripotent stem cells from a patient with spinocerebellar ataxia type 3. Stem cell research. vol 18. 2017-11-22. PMID:28395798. |
spinocerebellar ataxia type 3 (sca3) is a dominantly inherited neurodegenerative disease caused by a trinucleotide repeat (cag) expansion in the coding region of atxn3 gene resulting in production of ataxin-3 with an elongated polyglutamine tract. |
2017-11-22 |
2023-08-13 |
Not clear |
| Yoshihito Ishida, Hideshi Kawakami, Hiroyuki Kitajima, Ayaka Nishiyama, Yoshiki Sasai, Haruhisa Inoue, Keiko Mugurum. Vulnerability of Purkinje Cells Generated from Spinocerebellar Ataxia Type 6 Patient-Derived iPSCs. Cell reports. vol 17. issue 6. 2017-11-20. PMID:27806289. |
spinocerebellar ataxia type 6 (sca6) is a dominantly inherited neurodegenerative disease characterized by loss of purkinje cells in the cerebellum. |
2017-11-20 |
2023-08-13 |
Not clear |
| G Olivito, M Cercignani, M Lupo, C Iacobacci, S Clausi, S Romano, M Masciullo, M Molinari, M Bozzali, M Leggi. Neural substrates of motor and cognitive dysfunctions in SCA2 patients: A network based statistics analysis. NeuroImage. Clinical. vol 14. 2017-11-07. PMID:28393013. |
spinocerebellar ataxia type 2 (sca2) is an autosomal dominant neurodegenerative disease characterized by a progressive cerebellar syndrome, which can be isolated or associated with extracerebellar signs. |
2017-11-07 |
2023-08-13 |
Not clear |
| Susanne K Hansen, Helena Borland, Lis F Hasholt, Zeynep Tümer, Jørgen E Nielsen, Mikkel A Rasmussen, Troels T Nielsen, Tina C Stummann, Karina Fog, Poul Hytte. Generation of spinocerebellar ataxia type 3 patient-derived induced pluripotent stem cell line SCA3.A11. Stem cell research. vol 16. issue 3. 2017-10-30. PMID:27346190. |
spinocerebellar ataxia type 3 (sca3) is a dominantly inherited neurodegenerative disease caused by a cag-repeat expanding mutation in atxn3. |
2017-10-30 |
2023-08-13 |
Not clear |
| Susanne K Hansen, Helena Borland, Lis F Hasholt, Zeynep Tümer, Jørgen E Nielsen, Mikkel A Rasmussen, Troels T Nielsen, Tina C Stummann, Karina Fog, Poul Hytte. Generation of spinocerebellar ataxia type 3 patient-derived induced pluripotent stem cell line SCA3.B11. Stem cell research. vol 16. issue 3. 2017-10-30. PMID:27346191. |
spinocerebellar ataxia type 3 (sca3) is a dominantly inherited neurodegenerative disease caused by an expansion of the cag-repeat in atxn3. |
2017-10-30 |
2023-08-13 |
Not clear |
| A-Ram Kang, Hyoung-Tae An, Jesang Ko, Seongman Kan. Ataxin-1 regulates epithelial-mesenchymal transition of cervical cancer cells. Oncotarget. vol 8. issue 11. 2017-09-29. PMID:28212558. |
the mutant form of the protein ataxin-1 (atxn1) causes the neurodegenerative disease spinocerebellar ataxia type-1. |
2017-09-29 |
2023-08-13 |
Not clear |
| Marija Cvetanovic, Yuan-Shih Hu, Puneet Opa. Mutant Ataxin-1 Inhibits Neural Progenitor Cell Proliferation in SCA1. Cerebellum (London, England). vol 16. issue 2. 2017-09-22. PMID:27306906. |
spinocerebellar ataxia type 1 (sca1) is a dominantly inherited neurodegenerative disease caused by the expansion of a polyglutamine (q) repeat tract in the protein ataxin-1 (atxn1). |
2017-09-22 |
2023-08-13 |
mouse |