| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Teng Yu, Joshua Zuber, Jinchao L. Targeting autophagy in skin diseases. Journal of molecular medicine (Berlin, Germany). vol 93. issue 1. 2015-09-08. PMID:25404245. |
in addition to its vital homeostatic role, this degradation pathway has been implicated in many different cellular processes such as cell apoptosis, inflammation, pathogen clearance, and antigen presentation and thereby has been linked to a variety of human disorders, including metabolic conditions, neurodegenerative diseases, cancers, and infectious diseases. |
2015-09-08 |
2023-08-13 |
human |
| Norsharina Ismail, Maznah Ismail, Siti Farhana Fathy, Siti Nor Asma Musa, Mustapha Umar Imam, Jhi Biau Foo, Shahid Iqba. Neuroprotective effects of germinated brown rice against hydrogen peroxide induced cell death in human SH-SY5Y cells. International journal of molecular sciences. vol 13. issue 8. 2015-08-31. PMID:22949825. |
therefore, gbr could be developed as a value added functional food to prevent neurodegenerative diseases caused by oxidative stress and apoptosis. |
2015-08-31 |
2023-08-12 |
human |
| Raynoo Thanan, Shinji Oikawa, Yusuke Hiraku, Shiho Ohnishi, Ning Ma, Somchai Pinlaor, Puangrat Yongvanit, Shosuke Kawanishi, Mariko Murat. Oxidative stress and its significant roles in neurodegenerative diseases and cancer. International journal of molecular sciences. vol 16. issue 1. 2015-08-28. PMID:25547488. |
in neurodegenerative diseases, dna damage may not only play a role in the induction of apoptosis, but also may inhibit cellular division via telomere shortening. |
2015-08-28 |
2023-08-13 |
Not clear |
| Eleonora Passeri, Italo Mocchetti, Charbel Mouss. Is human immunodeficiency virus-mediated dementia an autophagic defect that leads to neurodegeneration? CNS & neurological disorders drug targets. vol 13. issue 9. 2015-08-19. PMID:25106633. |
autophagy may protect against neuronal apoptosis, which is induced in a number of neurodegenerative diseases. |
2015-08-19 |
2023-08-13 |
human |
| Giovanni Sorrentino, Anna Comel, Fiamma Mantovani, Giannino Del Sa. Regulation of mitochondrial apoptosis by Pin1 in cancer and neurodegeneration. Mitochondrion. vol 19 Pt A. 2015-08-03. PMID:25132079. |
in this review we will discuss the impact of pin1 in regulating various aspects of apoptosis in different biological contexts with particular emphasis on cancer and neurodegenerative diseases. |
2015-08-03 |
2023-08-13 |
Not clear |
| Ayşe Karababa, Boris Görg, Freimut Schliess, Dieter Häussinge. O-GlcNAcylation as a novel ammonia-induced posttranslational protein modification in cultured rat astrocytes. Metabolic brain disease. vol 29. issue 4. 2015-07-20. PMID:24292976. |
in view of the complex involvement of o-glcnacylation in cell regulation, such as energy metabolism, apoptosis and circadian rhythmicity and in pathologies, such as neurodegenerative diseases, o-glcnacylation might contribute to the pathophysiology of hepatic encephalopathy. |
2015-07-20 |
2023-08-12 |
rat |
| Valérie Jolivel, Sébastien Arthaud, Béatrice Botia, Christophe Portal, Bruno Delest, Guillaume Clavé, Jérôme Leprince, Anthony Romieu, Pierre-Yves Renard, Omar Touzani, Heidi Ligeret, Pauline Noack, Marc Massonneau, Alain Fournier, Hubert Vaudry, David Vaudr. Biochemical characterization of a Caspase-3 far-red fluorescent probe for non-invasive optical imaging of neuronal apoptosis. Journal of molecular neuroscience : MN. vol 54. issue 3. 2015-07-14. PMID:24865411. |
apoptosis is a regulated process, leading to cell death, which is involved in several pathologies including neurodegenerative diseases and stroke. |
2015-07-14 |
2023-08-13 |
Not clear |
| Elena Radi, Patrizia Formichi, Carla Battisti, Antonio Federic. Apoptosis and oxidative stress in neurodegenerative diseases. Journal of Alzheimer's disease : JAD. vol 42 Suppl 3. 2015-06-29. PMID:25056458. |
apoptosis and oxidative stress in neurodegenerative diseases. |
2015-06-29 |
2023-08-13 |
human |
| Elena Radi, Patrizia Formichi, Carla Battisti, Antonio Federic. Apoptosis and oxidative stress in neurodegenerative diseases. Journal of Alzheimer's disease : JAD. vol 42 Suppl 3. 2015-06-29. PMID:25056458. |
however, many dying neurons have been detected in brains of patients with neurodegenerative diseases, and these conditions are often associated with significant cell loss accompanied by typical morphological features of apoptosis such as chromatin condensation, dna fragmentation, and activation of cysteine-proteases, caspases. |
2015-06-29 |
2023-08-13 |
human |
| Elena Radi, Patrizia Formichi, Carla Battisti, Antonio Federic. Apoptosis and oxidative stress in neurodegenerative diseases. Journal of Alzheimer's disease : JAD. vol 42 Suppl 3. 2015-06-29. PMID:25056458. |
here we present an overview of the involvement of neuronal apoptosis and oxidative stress in the most important neurodegenerative diseases, mainly focusing the attention on several genetic disorders, discussing the interaction between primary genetic abnormalities and the apoptotic pathways. |
2015-06-29 |
2023-08-13 |
human |
| Mummedy Swamy, Dian Suhaili, K N S Sirajudeen, Zulkarnain Mustapha, Chandran Govindasam. Propolis ameliorates tumor nerosis factor-α, nitric oxide levels, caspase-3 and nitric oxide synthase activities in kainic acid mediated excitotoxicity in rat brain. African journal of traditional, complementary, and alternative medicines : AJTCAM. vol 11. issue 5. 2015-06-29. PMID:25395704. |
increased nitric oxide (no), neuronal inflammation and apoptosis have been proposed to be involved in excitotoxicity plays a part in many neurodegenerative diseases. |
2015-06-29 |
2023-08-13 |
rat |
| Agnieszka Kobylińska, Krystyna M Jana. [Health--promoting effect of quercetin in human diet]. Postepy higieny i medycyny doswiadczalnej (Online). vol 69. 2015-06-23. PMID:25589713. |
this compound at low concentrations can stimulate proliferation of human cells, so it can be a potential drug in the treatment of neurodegenerative diseases and in high concentrations, it induces apoptosis thereby eliminating the infected or abnormal cells and can serve as a potential anticancer drug with wide clinical application. |
2015-06-23 |
2023-08-13 |
human |
| Sandrine Jouan-Lanhouet, Franck Riquet, Linde Duprez, Tom Vanden Berghe, Nozomi Takahashi, Peter Vandenabeel. Necroptosis, in vivo detection in experimental disease models. Seminars in cell & developmental biology. vol 35. 2015-06-22. PMID:25160988. |
indeed, in addition to apoptosis, multiple forms of regulated necrosis have been associated with an increasing number of pathologies such as ischemia-reperfusion injury in brain, heart and kidney, inflammatory diseases, sepsis, retinal disorders, neurodegenerative diseases and infectious disorders. |
2015-06-22 |
2023-08-13 |
Not clear |
| Jung Soo Kim, Rok Won Heo, Hwajin Kim, Chin-Ok Yi, Hyun Joo Shin, Jong Woo Han, Gu Seob Ro. Salubrinal, ER stress inhibitor, attenuates kainic acid-induced hippocampal cell death. Journal of neural transmission (Vienna, Austria : 1996). vol 121. issue 10. 2015-06-16. PMID:24728926. |
parkin is an ubiquitin e3 ligase that mediates the ubiquitination of the bcl-2 family of proteins and its mutations are associated with neuronal apoptosis in neurodegenerative diseases. |
2015-06-16 |
2023-08-13 |
mouse |
| Grace Y Sun, Dennis Y Chuang, Yijia Zong, Jinghua Jiang, James C M Lee, Zezong Gu, Agnes Simony. Role of cytosolic phospholipase A2 in oxidative and inflammatory signaling pathways in different cell types in the central nervous system. Molecular neurobiology. vol 50. issue 1. 2015-06-10. PMID:24573693. |
in the central nervous system (cns), cpla(2) activation has been implicated in neuronal excitation, synaptic secretion, apoptosis, cell-cell interaction, cognitive and behavioral function, oxidative-nitrosative stress, and inflammatory responses that underline the pathogenesis of a number of neurodegenerative diseases. |
2015-06-10 |
2023-08-12 |
Not clear |
| Nicolas G Baza. Is there a molecular logic that sustains neuronal functional integrity and survival? Lipid signaling is necessary for neuroprotective neuronal transcriptional programs. Molecular neurobiology. vol 50. issue 1. 2015-06-10. PMID:25236258. |
in neurodegenerative diseases, apoptosis and other forms of cells death lead to selective neuronal loss. |
2015-06-10 |
2023-08-13 |
Not clear |
| Yiming Li, Yunshan Guo, Juan Tang, Jianli Jiang, Zhinan Che. New insights into the roles of CHOP-induced apoptosis in ER stress. Acta biochimica et biophysica Sinica. vol 46. issue 8. 2015-06-02. PMID:25016584. |
by now, chop-induced apoptosis in er stress has been implicated in numerous human diseases, such as neurodegenerative diseases, diabetes, ischemic diseases, tumor, and so on. |
2015-06-02 |
2023-08-13 |
human |
| Levent Tök, Mustafa Nazıroğlu, Abdülhadi Cihangir Uğuz, Ozlem Tö. Elevated hydrostatic pressures induce apoptosis and oxidative stress through mitochondrial membrane depolarization in PC12 neuronal cells: A cell culture model of glaucoma. Journal of receptor and signal transduction research. vol 34. issue 5. 2015-05-28. PMID:24809391. |
despite the importance of oxidative stress and apoptosis through mitochondrial depolarization in neurodegenerative diseases, their roles in etiology of glaucoma are poorly understood. |
2015-05-28 |
2023-08-13 |
rat |
| Wenna Chen, Ximing Li, Lian-Qun Jia, Jun Wang, Lin Zhang, Diandong Hou, Junyan Wang, Lu Re. Neuroprotective activities of catalpol against CaMKII-dependent apoptosis induced by LPS in PC12 cells. British journal of pharmacology. vol 169. issue 5. 2015-03-30. PMID:23550774. |
neurodegenerative diseases present progressive neurological disorder induced by cell death or apoptosis. |
2015-03-30 |
2023-08-12 |
Not clear |
| Ting Yu, Lei Li, Yanwen Bi, Zhen Liu, Huaxiang Liu, Zhenzhong L. Erythropoietin attenuates oxidative stress and apoptosis in Schwann cells isolated from streptozotocin-induced diabetic rats. The Journal of pharmacy and pharmacology. vol 66. issue 8. 2015-03-30. PMID:24673486. |
although erythropoietin (epo) was demonstrated to have neuroprotective effects in neurodegenerative diseases, the effects of epo on glucose-evoked oxidative stress and apoptosis of scs remain unknown. |
2015-03-30 |
2023-08-12 |
rat |