All Relations between Neurodegenerative Diseases and mesencephalon

Publication Sentence Publish Date Extraction Date Species
Jean-Louis A Parmasad, Konrad M Ricke, Benjamin Nguyen, Morgan G Stykel, Brodie Buchner-Duby, Amanda Bruce, Haley M Geertsma, Eric Lian, Nathalie A Lengacher, Steve M Callaghan, Alvin Joselin, Julianna J Tomlinson, Michael G Schlossmacher, William L Stanford, Jiyan Ma, Patrik Brundin, Scott D Ryan, Maxime W C Rousseau. Genetic and pharmacological reduction of CDK14 mitigates synucleinopathy. Cell death & disease. vol 15. issue 4. 2024-04-04. PMID:38575601. parkinson's disease (pd) is a debilitating neurodegenerative disease characterized by the loss of midbrain dopaminergic neurons (dans) and the abnormal accumulation of α-synuclein (α-syn) protein. 2024-04-04 2024-04-07 mouse
Lingling Zhang, Hao Yan. Research progress of neural stem cells as a source of dopaminergic neurons for cell therapy in Parkinson's disease. Molecular biology reports. vol 51. issue 1. 2024-02-24. PMID:38400887. parkinson's disease (pd) is a neurodegenerative disease, the most characteristic pathological feature is the progressive loss of dopaminergic (da) neurons in the substantia nigra pars compactus (snpc) of the mesencephalon, along with reduced dopamine content in the striatum. 2024-02-24 2024-02-27 Not clear
Meritxell Pons-Espinal, Lucas Blasco-Agell, Irene Fernandez-Carasa, Pol Andrés-Benito, Angelique di Domenico, Yvonne Richaud-Patin, Valentina Baruffi, Laura Marruecos, Lluís Espinosa, Alicia Garrido, Eduardo Tolosa, Michael J Edel, Manel Juan Otero, José Luis Mosquera, Isidre Ferrer, Angel Raya, Antonella Consigli. Blocking IL-6 signaling prevents astrocyte-induced neurodegeneration in an iPSC-based model of Parkinson's disease. JCI insight. vol 9. issue 3. 2024-02-08. PMID:38329129. parkinson's disease (pd) is a neurodegenerative disease associated with progressive death of midbrain dopamine (dan) neurons in the substantia nigra (sn). 2024-02-08 2024-02-10 human
Mudiwa N Muwanigwa, Jennifer Modamio-Chamarro, Paul M A Antony, Gemma Gomez-Giro, Rejko Krüger, Silvia Bolognin, Jens C Schwambor. Alpha-synuclein pathology is associated with astrocyte senescence in a midbrain organoid model of familial Parkinson's disease. Molecular and cellular neurosciences. 2024-02-02. PMID:38307302. parkinson's disease (pd) is a complex, progressive neurodegenerative disease characterized by the loss of dopaminergic neurons in the substantia nigra pars compacta in the midbrain. 2024-02-02 2024-02-05 human
Mathias Holsey Gramkow, Frederikke Kragh Clemmensen, Gunhild Waldemar, Steen Gregers Hasselbalch, Kristian Steen Frederikse. Test-retest reliability and short-term variability of quantitative light reflex pupillometry in a mixed memory clinic cohort. Journal of the neurological sciences. vol 456. 2023-12-28. PMID:38154247. quantitative light reflex pupillometry (qlrp) may be a promising digital biomarker in neurodegenerative diseases such as alzheimer's disease (ad), as neuropathological changes have been found in the midbrain structures governing the light reflex. 2023-12-28 2023-12-31 Not clear
Andrea Di Credico, Amélie Weiss, Massimo Corsini, Giulia Gaggi, Barbara Ghinassi, Johannes H Wilbertz, Angela Di Baldassarr. Machine learning identifies phenotypic profile alterations of human dopaminergic neurons exposed to bisphenols and perfluoroalkyls. Scientific reports. vol 13. issue 1. 2023-12-11. PMID:38081991. parkinson's disease (pd) is the second most common neurodegenerative disease and is characterized by the loss of midbrain dopaminergic neurons. 2023-12-11 2023-12-17 human
Nitu Kumari, Santosh Anand, Kamal Shah, Nagendra Singh Chauhan, Neeraj K Sethiya, Manmohan Singha. Emerging Role of Plant-Based Bioactive Compounds as Therapeutics in Parkinson's Disease. Molecules (Basel, Switzerland). vol 28. issue 22. 2023-11-25. PMID:38005310. pd stands second among the common neurodegenerative diseases caused as a result of dopaminergic neuron loss in the midbrain's substantia nigra regions. 2023-11-25 2023-11-28 Not clear
Jeffrey Kim, Etienne W Daadi, Elyas Sebastien Daadi, Thomas Oh, Michela Deleidi, Marcel M Daad. Cells. vol 12. issue 21. 2023-11-10. PMID:37947628. parkinson's disease (pd) is the second most prevalent neurodegenerative disease, characterized by the loss of midbrain dopaminergic neurons which leads to impaired motor and cognitive functions. 2023-11-10 2023-11-20 Not clear
Yalan Chen, Junxin Kuang, Yimei Niu, Hongyao Zhu, Xiaoxia Chen, Kwok-Fai So, Anding Xu, Lingling Sh. Multiple factors to assist human-derived induced pluripotent stem cells to efficiently differentiate into midbrain dopaminergic neurons. Neural regeneration research. vol 19. issue 4. 2023-10-16. PMID:37843228. midbrain dopaminergic neurons play an important role in the etiology of neurodevelopmental and neurodegenerative diseases. 2023-10-16 2023-11-08 human
Wen-Xiang Duan, Fen Wang, Jun-Yi Liu, Chun-Feng Li. Relationship Between Short-chain Fatty Acids and Parkinson's Disease: A Review from Pathology to Clinic. Neuroscience bulletin. 2023-09-27. PMID:37755674. parkinson's disease (pd) is a complicated neurodegenerative disease, characterized by the accumulation of α-synuclein (α-syn) in lewy bodies and neurites, and massive loss of midbrain dopamine neurons. 2023-09-27 2023-10-07 Not clear
Jia-Xin Shi, Ke-Zhong Zhan. Advancements in autologous stem cell transplantation for Parkinson's Disease. Current stem cell research & therapy. 2023-09-11. PMID:37691194. parkinson's disease (pd) is a progressive neurodegenerative disease marked by comparatively focal dopaminergic neuron degeneration in the substantia nigra of the midbrain and dopamine loss in the striatum, which causes motor and non-motor symptoms. 2023-09-11 2023-10-07 Not clear
Emmi Pakarinen, Päivi Lindhol. CDNF and MANF in the brain dopamine system and their potential as treatment for Parkinson's disease. Frontiers in psychiatry. vol 14. 2023-08-09. PMID:37555005. parkinson's disease (pd) is a progressive neurodegenerative disease characterized by gradual loss of midbrain dopamine neurons, leading to impaired motor function. 2023-08-09 2023-08-16 human
João D Magalhães, Emanuel Candeias, Inês Melo-Marques, Diana F Silva, A Raquel Esteves, Nuno Empadinhas, Sandra Morais Cardos. Intestinal infection triggers mitochondria-mediated α-synuclein pathology: relevance to Parkinson's disease. Cellular and molecular life sciences : CMLS. vol 80. issue 6. 2023-05-30. PMID:37249642. parkinson's disease (pd) is a multifactorial neurodegenerative disease characterized by the loss of dopaminergic neurons in the midbrain. 2023-05-30 2023-08-14 Not clear
Tatiana Gerasimova, Ekaterina Stepanenko, Lyudmila Novosadova, Elena Arsenyeva, Darya Shimchenko, Vyacheslav Tarantul, Igor Grivennikov, Valentina Nenasheva, Ekaterina Novosadov. Glial Cultures Differentiated from iPSCs of Patients with International journal of molecular sciences. vol 24. issue 3. 2023-02-11. PMID:36768317. glial cultures differentiated from ipscs of patients with parkinson's disease (pd) is the second most common neurodegenerative diseases characterized by progressive loss of midbrain dopaminergic neurons in the substantia nigra. 2023-02-11 2023-08-14 Not clear
Jessica K Smith, George D Mellick, Alex M Syke. The role of the endolysosomal pathway in α-synuclein pathogenesis in Parkinson's disease. Frontiers in cellular neuroscience. vol 16. 2023-01-27. PMID:36704248. parkinson's disease (pd) is a chronic neurodegenerative disease that is characterized by a loss of dopaminergic neurons in the substantia nigra pars compacta of the midbrain (snpc). 2023-01-27 2023-08-14 Not clear
Yue Wu, Zhongting Zhao, Naidi Yang, Chenqi Xin, Zheng Li, Jiajia Xu, Bo Ma, Kah-Leong Lim, Lin Li, Qiong Wu, Changmin Yu, Chengwu Zhan. Vitamin B12 Ameliorates the Pathological Phenotypes of Multiple Parkinson's Disease Models by Alleviating Oxidative Stress. Antioxidants (Basel, Switzerland). vol 12. issue 1. 2023-01-21. PMID:36671015. parkinson's disease (pd) is the second most common neurodegenerative disease characterized by progressive loss of dopaminergic neurons in the substantia nigra of the midbrain. 2023-01-21 2023-08-14 Not clear
Changcheng Lu, Shuhui Qu, Zhangfeng Zhong, Hua Luo, Si San Lei, Hai-Jing Zhong, Huanxing Su, Yitao Wang, Cheong-Meng Chon. The effects of bioactive components from the rhizome of Frontiers in pharmacology. vol 13. 2022-12-19. PMID:36532787. the effects of bioactive components from the rhizome of parkinson's disease (pd) is an age-related chronic neurodegenerative disease caused by the death and degeneration of dopaminergic neurons in the substantia nigra of the midbrain. 2022-12-19 2023-08-14 Not clear
Ahsas Goyal, Anant Agrawal, Aanchal Verma, Nandini Dube. The PI3K-AKT pathway: A plausible therapeutic target in Parkinson's disease. Experimental and molecular pathology. 2022-11-27. PMID:36436571. parkinson's disease is a common progressive and multifactorial neurodegenerative disease, characterized by the loss of midbrain dopaminergic neurons. 2022-11-27 2023-08-14 Not clear
Yao-Lin Li, Zhong-Xuan Wang, Chang-Zhou Ying, Bao-Rong Zhang, Jia-Li P. Decoding the Role of Familial Parkinson's Disease-Related Genes in DNA Damage and Repair. Aging and disease. vol 13. issue 5. 2022-10-03. PMID:36186134. parkinson's disease (pd) is a neurodegenerative disease characterized by the degeneration of midbrain substantia nigra pars compacta dopaminergic neurons and the formation of lewy bodies. 2022-10-03 2023-08-14 Not clear
Da Woon Lee, Young-Kyoung Ryu, Dong-Ho Chang, Hye-Yeon Park, Jun Go, So-Young Maeng, Dae Youn Hwang, Byoung-Chan Kim, Chul-Ho Lee, Kyoung-Shim Ki. Journal of microbiology and biotechnology. vol 32. issue 9. 2022-09-28. PMID:36168204. parkinson's disease (pd) is the second-most prevalent neurodegenerative disease and is characterized by dopaminergic neuronal death in the midbrain. 2022-09-28 2023-08-14 Not clear