| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Isis Atallah, Ana M Cieza Rivera, Octavio M Rivero Lezcano, Laura Tascón-González, Carolina González-Cortés, Cristina Diez Tascón, Tania Fernández-Villa, Vicente Martí. Increased serum concentrations of estrogen-induced growth factors Midkine and FGF2 in NF1 patients with plexiform neurofibroma. American journal of translational research. vol 14. issue 5. 2022-06-15. PMID:35702135. |
this study aimed to determine whether, in nf1 patients, serum levels of midkine (mk) and fibroblast growth factor 2 (fgf2) were associated with the number and/or type of neurofibromas. |
2022-06-15 |
2023-08-14 |
Not clear |
| Mengying Peng, Yuqing Zhang, Qiong Zho. A case report of a 4-year-old girl with neurofibromatosis type 1. Cancer treatment and research communications. vol 32. 2022-06-10. PMID:35688104. |
nf1 patients were associated with multisystem involvement, characterized by neurofibroma, of which 50% were associated with plexus neurofibroma. |
2022-06-10 |
2023-08-14 |
Not clear |
| Ken-Ichi Yasuda, Yoshimasa Nobeyama, Akihiko Asahin. Improved renal function in neurofibromatosis type 1 patients. Skin health and disease. vol 2. issue 2. 2022-06-09. PMID:35677927. |
neurofibromatosis type 1 (nf1), or von recklinghausen disease, is an autosomal dominant disease that presents with various symptoms, including café-au-lait spots and neurofibromas. |
2022-06-09 |
2023-08-14 |
Not clear |
| Corina Anastasaki, Juan Mo, Ji-Kang Chen, Jit Chatterjee, Yuan Pan, Suzanne M Scheaffer, Olivia Cobb, Michelle Monje, Lu Q Le, David H Gutman. Neuronal hyperexcitability drives central and peripheral nervous system tumor progression in models of neurofibromatosis-1. Nature communications. vol 13. issue 1. 2022-05-19. PMID:35589737. |
in contrast, mice with the arg1809cys nf1 mutation, found in nf1 patients lacking neurofibromas or optic gliomas, do not exhibit neuronal hyperexcitability or develop these nf1-associated tumors. |
2022-05-19 |
2023-08-13 |
mouse |
| L Fertitta, C Bergqvist, M L Armand, S Moryousef, S Ferkal, A Jannic, P Ravaud, V T Tran, K Ezzedine, P Wolkenstei. Quality of life in neurofibromatosis 1: development and validation of a tool dedicated to cutaneous neurofibromas in adults. Journal of the European Academy of Dermatology and Venereology : JEADV. 2022-04-12. PMID:35412677. |
cutaneous neurofibromas (cnf), present in 95% of individuals with neurofibromatosis 1 (nf1), are considered as one of the greatest medical burden because of physical disfigurement. |
2022-04-12 |
2023-08-13 |
Not clear |
| Vivian N Okonta, Fataneh Majlessipour, Nicole M Bac. Ganglioneuroblastoma in a Child With Neurofibromatosis Type 1: A Case Report and Literature Review. Journal of pediatric hematology/oncology. 2022-04-10. PMID:35398860. |
though pediatric patients with nf1 have an increased risk of tumors such as optic gliomas and neurofibromas during childhood, neuroblastic tumors are less often observed in this population. |
2022-04-10 |
2023-08-13 |
Not clear |
| Basu Dawar, Ian Rothwell, Hardeep-Singh Mudhar, Jacqueline Eason, Christopher Knap. Primary lacrimal gland plexiform neurofibroma: a case report and review of the literature. Orbit (Amsterdam, Netherlands). 2022-03-21. PMID:35312416. |
neurofibromatosis type 1 (nf1) affects cell growth in neural tissues, resulting in neurofibromas of the internal organs, peripheral nerves and/or autonomic nerves. |
2022-03-21 |
2023-08-13 |
Not clear |
| Po-Yuan Huang, I-An Shih, Ying-Chih Liao, Huey-Ling You, Ming-Jen Le. A novel HDAC11 inhibitor potentiates the tumoricidal effects of cordycepin against malignant peripheral nerve sheath tumor through the Hippo signaling pathway. American journal of cancer research. vol 12. issue 2. 2022-03-09. PMID:35261809. |
clinically, the hallmarks of nf1 include skin pigmentation and cutaneous neurofibroma. |
2022-03-09 |
2023-08-13 |
Not clear |
| Awni Shahait, Tanya Odisho, Bayan Alshare, Lana J Alghanem, Donald Weave. An Unusual Cause of Adrenal Mass in Neurofibromatosis Type 1: Malignant Peripheral Nerve Sheath Tumor. Cureus. vol 14. issue 1. 2022-03-07. PMID:35251852. |
a malignant peripheral nerve sheath tumor (mpnst) is an aggressive tumor that can arise from the malignant transformation of benign neurofibromas in patients with neurofibromatosis type 1 (nf1). |
2022-03-07 |
2023-08-13 |
Not clear |
| Jaemin Choi, Sungbin An, So Young Li. Current concepts of neurofibromatosis type 1: pathophysiology and treatment. Archives of craniofacial surgery. vol 23. issue 1. 2022-03-07. PMID:35255591. |
abbreviations: calms, café-au-lait macules; cns, cutaneous neurofibromas; fdg, 18f-fluoro-deoxy-glucose; mapk, mitogen-activated protein kinase; mpnsts, malignant peripheral nerve sheath tumors; mri, magnetic resonance imaging; nf1, neurofibromatosis type 1; nih, national institutes of health; pet, positron emission tomography; pn, plexiform neurofibromas; tme, tumor microenvironment. |
2022-03-07 |
2023-08-13 |
Not clear |
| Hildegard Kehrer-Sawatzki, Ute Bäzner, Johannes Krämer, Jan Lewerenz, Christiane Pfeiffe. The NF1 microdeletion syndrome: early genetic diagnosis facilitates the management of a clinically defined disease. Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG. 2022-03-05. PMID:35246941. |
furthermore, cutaneous and subcutaneous neurofibromas present at an early age, severe global developmental delay and cognitive disability are pathognomonic for the "nf1 microdeletion syndrome". |
2022-03-05 |
2023-08-13 |
Not clear |
| Deborah Staber, Julia Oppold, Alexander Grimm, Martin U Schuhmann, Alyssa Romano, Justus Marquetand, Benedict Kleise. Shear-Wave-Elastography in Neurofibromatosis Type I. Diagnostics (Basel, Switzerland). vol 12. issue 2. 2022-02-25. PMID:35204451. |
given the lack of studies, a first step would be to investigate homogeneous peripheral nerve tumors (pnts), histologically neurofibromas or schwannomas, which can occur in multiple in neurofibromatosis type 1 and 2 (nf1 and 2), respectively. |
2022-02-25 |
2023-08-13 |
Not clear |
| Massimo Mesolella, Salvatore Allosso, Luigi Insabato, Raduan Ahmed Franca, Grazia Salern. Isolated neurofibromas of the great auricular nerve: A rare localization in a pediatric patient with neurofibromatosis type-1. Ear, nose, & throat journal. 2022-02-21. PMID:35187958. |
we report a case of circumscribed solitary neurofibromas in a 14-year-old boy with nf1 who presented to our department with a left neck swelling. |
2022-02-21 |
2023-08-13 |
Not clear |
| Alessandra Santos, Mauro Geller, Spyros Mezitis, Allan E Rubenstein, Lisa Oliveira, Daniel Jm Medeiros Lima, Mendel Suchmacher Neto, Rafael Nigri, Karin Gonçalves Soares Cunha, Sanyu Takirambudde, Marcia Gonçalves Ribeir. Determination of Vitamin D Levels in Patients With Neurofibromatosis Type 1 in the Pediatric Age Group. Clinical pathology (Thousand Oaks, Ventura County, Calif.). vol 13. 2022-02-14. PMID:35156025. |
decreased serum 25-hydroxyvitamin d (vitamin d) levels have been noted in adults and children with nf1 and have been reported to be inversely correlated with the number of dermal neurofibromas in adults. |
2022-02-14 |
2023-08-13 |
Not clear |
| Alessandra Santos, Mauro Geller, Spyros Mezitis, Allan E Rubenstein, Lisa Oliveira, Daniel Jm Medeiros Lima, Mendel Suchmacher Neto, Rafael Nigri, Karin Gonçalves Soares Cunha, Sanyu Takirambudde, Marcia Gonçalves Ribeir. Determination of Vitamin D Levels in Patients With Neurofibromatosis Type 1 in the Pediatric Age Group. Clinical pathology (Thousand Oaks, Ventura County, Calif.). vol 13. 2022-02-14. PMID:35156025. |
however, the actual correlation of vitamin d level to bone density and dermal neurofibroma number in children with nf1 remains unclear. |
2022-02-14 |
2023-08-13 |
Not clear |
| Florentina Năstase, Diana Sabina Radaschin, Elena Niculeț, Andrei Vlad Brădeanu, Mădălina Codruța Verenca, Aurel Nechita, Valentin Chioncel, Lawrence Chukwudi Nwabudike, Liliana Baroiu, Eduard Drima Polea, Silvia Fotea, Lucretia Anghel, Alexandru Nechifor, Alin Laurenţiu Tat. Orthopaedic manifestations of neurofibromatosis type 1: A case report. Experimental and therapeutic medicine. vol 23. issue 2. 2022-01-24. PMID:35069816. |
the diagnosis is determined on two out of seven criteria: i) a total of 6 or more light brown spots larger than 5 mm in diameter (pre-puberty) or 15 mm in diameter (post-puberty); ii) a total of 2 or more neurofibromas or one plexiform neurofibroma; iii) axillary or inguinal freckling; iv) optic glioma; v) a total of 2 or more lisch nodules; vi) bone abnormalities: tibia pseudarthrosis or dysplasia of the sphenoid wing; and vii) a relative of first degree having an nf1 diagnosis. |
2022-01-24 |
2023-08-13 |
Not clear |
| Anja Harde. Do non-pathogenic variants of DNA mismatch repair genes modify neurofibroma load in neurofibromatosis type 1? Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery. 2022-01-08. PMID:34997843. |
patients with autosomal dominant nf1 typically develop neurofibromas ranging from single to thousands. |
2022-01-08 |
2023-08-13 |
Not clear |
| Anja Harde. Do non-pathogenic variants of DNA mismatch repair genes modify neurofibroma load in neurofibromatosis type 1? Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery. 2022-01-08. PMID:34997843. |
concerning the number of neurofibromas nf1 patients face a situation that is still not predictable. |
2022-01-08 |
2023-08-13 |
Not clear |
| Anja Harde. Do non-pathogenic variants of DNA mismatch repair genes modify neurofibroma load in neurofibromatosis type 1? Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery. 2022-01-08. PMID:34997843. |
a few studies suggested that germline non-pathogenic mmr gene variants modify the number of neurofibromas in nf1 and by this mechanism may promote the extent of neurofibroma manifestation. |
2022-01-08 |
2023-08-13 |
Not clear |
| Anja Harde. Do non-pathogenic variants of DNA mismatch repair genes modify neurofibroma load in neurofibromatosis type 1? Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery. 2022-01-08. PMID:34997843. |
this review represents first evidence that specific non-pathogenic single nucleotide variants of mmr genes act as a modifier of neurofibroma manifestation in nf1, highlighting msh2 re4987188 as the best analysed non-pathogenic variant so far. |
2022-01-08 |
2023-08-13 |
Not clear |