| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Bethany Cartwright, Kenneth Corsa. Neurofibroma of the hard palate. BMJ case reports. vol 14. issue 4. 2021-05-14. PMID:33827870. |
an incisional biopsy was performed, which confirmed the diagnosis of a neurofibroma associated with nf1. |
2021-05-14 |
2023-08-13 |
Not clear |
| Alexander Pemov, Nancy F Hansen, Sivasish Sindiri, Rajesh Patidar, Christine S Higham, Eva Dombi, Markku M Miettinen, Patricia Fetsch, Hilde Brems, Settara C Chandrasekharappa, Kristine Jones, Bin Zhu, Jun S Wei, James C Mullikin, Margaret R Wallace, Javed Khan, Eric Legius, Brigitte C Widemann, Douglas R Stewar. Low mutation burden and frequent loss of CDKN2A/B and SMARCA2, but not PRC2, define premalignant neurofibromatosis type 1-associated atypical neurofibromas. Neuro-oncology. vol 21. issue 8. 2021-04-27. PMID:30722027. |
nf1 patients have an 8-16% lifetime risk of developing a malignant peripheral nerve sheath tumor (mpnst), a highly aggressive soft-tissue sarcoma, often arising from preexisting benign plexiform neurofibromas (pns) and atypical neurofibromas (anfs). |
2021-04-27 |
2023-08-13 |
Not clear |
| Sara H Osum, Adrienne L Watson, David A Largaespad. Spontaneous and Engineered Large Animal Models of Neurofibromatosis Type 1. International journal of molecular sciences. vol 22. issue 4. 2021-04-26. PMID:33669386. |
spontaneous nf-like symptoms including neurofibromas and malignant peripheral nerve sheath tumors (mpnst) have been documented in several large animal species and share biological and clinical similarities with human nf1. |
2021-04-26 |
2023-08-13 |
mouse |
| Eungu Kang, Hee Mang Yoon, Beom Hee Le. Neurofibromatosis type I: points to be considered by general pediatricians. Clinical and experimental pediatrics. vol 64. issue 4. 2021-04-15. PMID:32683805. |
neurofibromatosis type 1 (nf1), a prevalent genetic disease that is transmitted in an autosomal dominant manner, is characterized by multiple cutaneous café-au-lait spots and neurofibromas as well as various degrees of neurological, skeletal, and neoplastic manifestations. |
2021-04-15 |
2023-08-13 |
Not clear |
| Lisa Brauer Oliveira, Mauro Geller, Karin Soares Cunha, Alessandra Santos, Allan Bernacchi, Allan E Rubenstein, Sanyu Takirambudde, Spyros Mezitis, Carolina de Almeida Ito Brum, Luiz Guilherme Darrigo, Marcia Gonçalves Ribeir. Clinical assessment of the use of topical liquid diclofenac following laser microporation of cutaneous neurofibromas in individuals with neurofibromatosis type 1. Heliyon. vol 7. issue 3. 2021-04-06. PMID:33817379. |
cutaneous neurofibromas (cnf) are among the most common visible manifestations of nf1 and present a major clinical burden for patients. |
2021-04-06 |
2023-08-13 |
Not clear |
| Angela C Hirbe, Rebecca D Dodd, Christine A Pratila. Special Issue: "Genomics and Models of Nerve Sheath Tumors". Genes. vol 11. issue 9. 2021-03-31. PMID:32882803. |
nerve sheath tumors arising in the context of neurofibromatosis type 1 (nf1) include benign tumors such as cutaneous, diffuse and plexiform neurofibromas; atypical neurofibromas or atypical neurofibromatosis neoplasms of uncertain biological potential (annubp); and the aggressive soft tissue sarcoma, the malignant peripheral nerve sheath tumor (mpnst) [...]. |
2021-03-31 |
2023-08-13 |
Not clear |
| Tokimasa Hida, Masashi Idogawa, Masae Okura, Shintaro Sugita, Taro Sugawara, Yasushi Sasaki, Takashi Tokino, Toshiharu Yamashita, Hisashi Uhar. Genetic analyses of mosaic neurofibromatosis type 1 with giant café-au-lait macule, plexiform neurofibroma and multiple melanocytic nevi. The Journal of dermatology. vol 47. issue 6. 2021-03-15. PMID:32246533. |
a second-hit nf1 aberration results in the formation of café-au-lait macules, cutaneous neurofibroma and plexiform neurofibroma (pnf). |
2021-03-15 |
2023-08-13 |
Not clear |
| Yan Zhang, Hongfei Cai, Guangchao Lv, Yang L. A giant posterior mediastinal malignant peripheral nerve sheath tumor and benign neurofibroma in body surface: a case report. BMC surgery. vol 21. issue 1. 2021-03-15. PMID:33691671. |
major tumor type of nf1 are neurofibroma recognized as benign peripheral nerve tumor, malignant peripheral nerve sheath tumor (mpnst), and glioma. |
2021-03-15 |
2023-08-13 |
Not clear |
| Allen Mao, Hunaid N Rana, Mohamed Elramah, Brett Marti. An Unusual Case of Retroperitoneal Plexiform Neurofibromas Found in a Trauma Patient. Cureus. vol 13. issue 1. 2021-03-05. PMID:33659131. |
however, multiple neurofibromas are the pathognomonic hallmark of nf1. |
2021-03-05 |
2023-08-13 |
Not clear |
| Allen Mao, Hunaid N Rana, Mohamed Elramah, Brett Marti. An Unusual Case of Retroperitoneal Plexiform Neurofibromas Found in a Trauma Patient. Cureus. vol 13. issue 1. 2021-03-05. PMID:33659131. |
the radiographic features of neurofibromas are described in addition to the discussion of management and prognosis of nf1. |
2021-03-05 |
2023-08-13 |
Not clear |
| Jacob C Balmer, Yana Mikhaylov, David N Lewin, David M Mahvi, E Ramsay Cam. Synchronous Upper Intestinal Neurofibromas and Duodenal Periampullary Well-Differentiated Neuroendocrine Tumor Associated With Neurofibromatosis 1. The American surgeon. vol 87. issue 1. 2021-02-25. PMID:32856931. |
our patient underwent a whipple for symptomatic neurofibromas associated with nf1 and was unexpectedly discovered to have a metastatic duodenal well-differentiated neuroendocrine tumor. |
2021-02-25 |
2023-08-13 |
Not clear |
| Jacob C Balmer, Yana Mikhaylov, David N Lewin, David M Mahvi, E Ramsay Cam. Synchronous Upper Intestinal Neurofibromas and Duodenal Periampullary Well-Differentiated Neuroendocrine Tumor Associated With Neurofibromatosis 1. The American surgeon. vol 87. issue 1. 2021-02-25. PMID:32856931. |
the patient is a 66-year-old man with nf1 who presented with hematemesis and was found to have large gastric neurofibromas and an ampullary neurofibroma based on endoscopy and radiological imaging. |
2021-02-25 |
2023-08-13 |
Not clear |
| Pamela Brock, Jean Bustamante Alvarez, Amir Mortazavi, Sameek Roychowdhury, John Phay, Raheela A Khawaja, Manisha H Shah, Bhavana Kond. Co-occurrence of multiple endocrine neoplasia type 4 and spinal neurofibromatosis: a case report. Familial cancer. vol 19. issue 2. 2021-02-24. PMID:32052251. |
spinal neurofibromatosis (snf) is an uncommon subtype of neurofibromatosis type 1 (nf1) characterized by bilateral neurofibromas of all spinal roots. |
2021-02-24 |
2023-08-13 |
Not clear |
| Hisashi Murakami, Tomohiro Sonoo, Hideki Hashimoto, Kensuke Nakamur. Pheochromocytoma crisis in a patient with newly diagnosed neurofibromatosis type 1. BMJ case reports. vol 14. issue 1. 2021-02-22. PMID:33495177. |
characteristic skin lesions such as café-au-lait macules and neurofibromas contributed to the diagnosis of nf1 and pheochromocytoma. |
2021-02-22 |
2023-08-13 |
Not clear |
| Hisashi Murakami, Tomohiro Sonoo, Hideki Hashimoto, Kensuke Nakamur. Pheochromocytoma crisis in a patient with newly diagnosed neurofibromatosis type 1. BMJ case reports. vol 14. issue 1. 2021-02-22. PMID:33495177. |
primary care physicians must distinguish the characteristic skin lesions of nf1, such as café-au-lait macules and neurofibromas and recognise the risk for pheochromocytoma. |
2021-02-22 |
2023-08-13 |
Not clear |
| Katrien Van de Steen, Robert Riedl, Sébastien Strypstein, Evert-Jan Boerm. Appendiceal neurofibroma and diverticula in a neurofibromatosis type 1 patient with chronic right lower quadrant pain. BMJ case reports. vol 13. issue 6. 2021-02-12. PMID:32499294. |
the most common presentations of nf1 are cutaneous presentations like café-au-lait spots and neurofibromas. |
2021-02-12 |
2023-08-13 |
Not clear |
| Katrien Van de Steen, Robert Riedl, Sébastien Strypstein, Evert-Jan Boerm. Appendiceal neurofibroma and diverticula in a neurofibromatosis type 1 patient with chronic right lower quadrant pain. BMJ case reports. vol 13. issue 6. 2021-02-12. PMID:32499294. |
in patients with nf1 with right lower quadrant pain benign appendiceal neurofibroma should be included in the differential diagnosis. |
2021-02-12 |
2023-08-13 |
Not clear |
| Lester D R Thompson, Stephen S Koh, Sean K La. Sporadic Neurofibroma of the Tongue Unassociated with Neurofibromatosis Type I: A Clinicopathologic Study of Ten Cases. Head and neck pathology. vol 14. issue 2. 2021-02-04. PMID:31111316. |
the majority of lingual neurofibromas arise in patients affected by neurofibromatosis type 1 (nf1). |
2021-02-04 |
2023-08-13 |
Not clear |
| Lester D R Thompson, Stephen S Koh, Sean K La. Sporadic Neurofibroma of the Tongue Unassociated with Neurofibromatosis Type I: A Clinicopathologic Study of Ten Cases. Head and neck pathology. vol 14. issue 2. 2021-02-04. PMID:31111316. |
this series of cases confirms that sporadic neurofibromas of the tongue may be rarely encountered in patients having no other features of nf1. |
2021-02-04 |
2023-08-13 |
Not clear |
| Katherine E Chaney, Melissa R Perrino, Leah J Kershner, Ami V Patel, Jianqiang Wu, Kwangmin Choi, Tilat A Rizvi, Eva Dombi, Sara Szabo, David A Largaespada, Nancy Ratne. Cancer research. vol 80. issue 21. 2021-02-02. PMID:32816910. |
here we combined loss of nf1 in developing schwann cells with global ink4a/arf loss and identified paraspinal plexiform neurofibromas and atypical neurofibromas. |
2021-02-02 |
2023-08-13 |
mouse |