| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Michael A Matar, Hagit Cohen, Zeev Kaplan, Joseph Zoha. The effect of early poststressor intervention with sertraline on behavioral responses in an animal model of post-traumatic stress disorder. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 31. issue 12. 2007-01-05. PMID:16794565. |
whereas several well-controlled studies have established the selective serotonin reuptake inhibitors (ssris) as the recommended first-line pharmacotherapeutic agents for acute and chronic post-traumatic stress disorder (ptsd), drug interventions in the acute postexposure phase have not been studied to the same extent and tend to be largely speculative. |
2007-01-05 |
2023-08-12 |
rat |
| Eileen P Ahearn, Mary Mussey, Catherine Johnson, Amy Krohn, Dean Krah. Quetiapine as an adjunctive treatment for post-traumatic stress disorder: an 8-week open-label study. International clinical psychopharmacology. vol 21. issue 1. 2006-09-19. PMID:16317314. |
this study evaluated the effectiveness of quetiapine for subjects with post-traumatic stress disorder (ptsd) who were already on a stable dose of a selective serotonin reuptake inhibitor (ssri) but had significant ptsd symptoms. |
2006-09-19 |
2023-08-12 |
human |
| Martin A Katzman, Lukasz Struzik, Lisa L Vivian, Monica Vermani, Joanna C McBrid. Pharmacotherapy of post-traumatic stress disorder: a family practitioners guide to management of the disease. Expert review of neurotherapeutics. vol 5. issue 1. 2006-04-18. PMID:15853483. |
the current evidence-based pharmacologic management approaches to post-traumatic stress disorder, suggests that first-line treatments for monotherapy are the selective serotonin reuptake inhibitors, sertraline, paroxetine and fluoxetine. |
2006-04-18 |
2023-08-12 |
Not clear |
| D E Ra. CINP 2000 - Collegium Internationale Neuro-Psychopharmacologicum 22nd Congress. IDrugs : the investigational drugs journal. vol 3. issue 9. 2005-09-20. PMID:16049859. |
paroxetine (novo nordisk a/s), a selective serotonin reuptake inhibitor (ssri), has just completed a multicenter clinical trial, being effective in about 50% of cases of post-traumatic stress disorder. |
2005-09-20 |
2023-08-12 |
Not clear |
| John J Worthington, Gustavo Kinrys, Lisa E Wygant, Mark H Pollac. Aripiprazole as an augmentor of selective serotonin reuptake inhibitors in depression and anxiety disorder patients. International clinical psychopharmacology. vol 20. issue 1. 2005-05-10. PMID:15602109. |
we report on patients with depression and anxiety disorders, including panic disorder, generalized anxiety disorder, social anxiety and post-traumatic stress disorder, who had an incomplete response to a variety of selective serotonin reuptake inhibitors (ssris) and who received augmentation with aripiprazole. |
2005-05-10 |
2023-08-12 |
human |
| Catherine C Crone, Geoffrey M Gabrie. Treatment of anxiety and depression in transplant patients: pharmacokinetic considerations. Clinical pharmacokinetics. vol 43. issue 6. 2004-07-26. PMID:15086275. |
selective serotonin reuptake inhibitors are well tolerated and efficacious for depression, panic disorder and post-traumatic stress disorder. |
2004-07-26 |
2023-08-12 |
Not clear |
| M Jakovljević, M Sagud, A Mihaljević-Pele. Olanzapine in the treatment-resistant, combat-related PTSD--a series of case reports. Acta psychiatrica Scandinavica. vol 107. issue 5. 2003-09-11. PMID:12752037. |
nightmares and insomnia in combat-related post-traumatic stress disorder (ptsd) might be resistant to treatment with selective serotonin reuptake inhibitors (ssris) and benzodiazepines. |
2003-09-11 |
2023-08-12 |
Not clear |
| Adrienne Z Ables, Otis L Baughma. Antidepressants: update on new agents and indications. American family physician. vol 67. issue 3. 2003-03-12. PMID:12588077. |
new indications for selective serotonin reuptake inhibitors include post-traumatic stress disorder, premenstrual dysphoric disorder, and generalized anxiety disorder. |
2003-03-12 |
2023-08-12 |
Not clear |
| Ann C Schwartz, Barbara O Rothbau. Review of sertraline in post-traumatic stress disorder. Expert opinion on pharmacotherapy. vol 3. issue 10. 2003-03-03. PMID:12387695. |
sertraline (zoloft trade mark, pfizer) is a selective serotonin re-uptake inhibitor (ssri) with proven efficacy in the treatment of post-traumatic stress disorder (ptsd). |
2003-03-03 |
2023-08-12 |
Not clear |
| D J Stein, S Seedat, G J van der Linden, N Zungu-Dirway. Selective serotonin reuptake inhibitors in the treatment of post-traumatic stress disorder: a meta-analysis of randomized controlled trials. International clinical psychopharmacology. vol 15 Suppl 2. 2001-04-26. PMID:11110017. |
selective serotonin reuptake inhibitors in the treatment of post-traumatic stress disorder: a meta-analysis of randomized controlled trials. |
2001-04-26 |
2023-08-12 |
Not clear |
| S Seedat, R Lockhat, D Kaminer, N Zungu-Dirwayi, D J Stei. An open trial of citalopram in adolescents with post-traumatic stress disorder. International clinical psychopharmacology. vol 16. issue 1. 2001-04-05. PMID:11195256. |
in this preliminary, 12-week open-label study, eight adolescents with moderate to severe post-traumatic stress disorder (ptsd) were treated with citalopram (the most selective of the selective serotonin reuptake inhibitors) in a fixed daily dose of 20 mg, and rated at 2-week intervals. |
2001-04-05 |
2023-08-12 |
Not clear |
| S Meltzer-Brody, K M Connor, E Churchill, J R Davidso. Symptom-specific effects of fluoxetine in post-traumatic stress disorder. International clinical psychopharmacology. vol 15. issue 4. 2001-01-11. PMID:10954063. |
the selective serotonin reuptake inhibitors have become a first line treatment for post-traumatic stress disorder (ptsd). |
2001-01-11 |
2023-08-12 |
Not clear |
| R B Hidalgo, J R Davidso. Selective serotonin reuptake inhibitors in post-traumatic stress disorder. Journal of psychopharmacology (Oxford, England). vol 14. issue 1. 2000-06-06. PMID:10757257. |
selective serotonin reuptake inhibitors in post-traumatic stress disorder. |
2000-06-06 |
2023-08-12 |
Not clear |
| K Maguire, T Norman, G Burrows, M Hopwood, P Morri. Platelet paroxetine binding in post-traumatic stress disorder. Psychiatry research. vol 77. issue 1. 2000-03-31. PMID:10710169. |
sixty-two subjects, 45 with post-traumatic stress disorder (ptsd) and 17 healthy control subjects, were examined in a study of serotonin function measured by [3h]paroxetine binding to platelet membranes. |
2000-03-31 |
2023-08-12 |
human |
| A J Flin. Management of anxiety in late life. Journal of geriatric psychiatry and neurology. vol 11. issue 4. 1999-06-15. PMID:10230998. |
uncontrolled data support the use of selective serotonin reuptake inhibitors in war veterans with chronic symptoms of post-traumatic stress disorder; other treatments for this condition await evaluation in the elderly. |
1999-06-15 |
2023-08-12 |
Not clear |
| R Hidalgo, M A Hertzberg, T Mellman, F Petty, P Tucker, R Weisler, S Zisook, S Chen, E Churchill, J Davidso. Nefazodone in post-traumatic stress disorder: results from six open-label trials. International clinical psychopharmacology. vol 14. issue 2. 1999-06-01. PMID:10220119. |
nefazodone, an antidepressant which blocks serotonin (5-ht)2 receptors and 5-ht reuptake, was evaluated in the treatment of post-traumatic stress disorder (ptsd) in six open-label studies involving both civilians and combat veterans. |
1999-06-01 |
2023-08-12 |
Not clear |
| b' M Maes, A H Lin, R Verkerk, L Delmeire, A Van Gastel, M Van der Planken, S Scharp\\xc3\\xa. Serotonergic and noradrenergic markers of post-traumatic stress disorder with and without major depression. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 20. issue 2. 1999-03-29. PMID:9885798.' |
some studies have suggested that disorders in the peripheral and central metabolism of serotonin (5-ht) and noradrenaline (ne) may play roles in the pathophysiology of post-traumatic stress disorder (ptsd). |
1999-03-29 |
2023-08-12 |
human |
| L L Davis, A Suris, M T Lambert, C Heimberg, F Pett. Post-traumatic stress disorder and serotonin: new directions for research and treatment. Journal of psychiatry & neuroscience : JPN. vol 22. issue 5. 1998-01-30. PMID:9401312. |
post-traumatic stress disorder and serotonin: new directions for research and treatment. |
1998-01-30 |
2023-08-12 |
Not clear |
| L L Davis, A Suris, M T Lambert, C Heimberg, F Pett. Post-traumatic stress disorder and serotonin: new directions for research and treatment. Journal of psychiatry & neuroscience : JPN. vol 22. issue 5. 1998-01-30. PMID:9401312. |
the overlap in clinical phenomenology and morbidity between post-traumatic stress disorder (ptsd) and such conditions as major depression, anxiety disorders and aggression, in which a serotonin dysfunction is implicated, suggests a role for serotonin in the pathophysiology of ptsd. |
1998-01-30 |
2023-08-12 |
Not clear |
| R C Arora, C G Fichtner, F O'Connor, J W Crayto. Paroxetine binding in the blood platelets of post-traumatic stress disorder patients. Life sciences. vol 53. issue 11. 1993-10-01. PMID:8366759. |
platelet serotonin (5-ht) uptake, as determined by 3h-paroxetine (pa) binding, was studied in 20 post-traumatic stress disorder (ptsd) patients and 20 normal controls. |
1993-10-01 |
2023-08-12 |
Not clear |