| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R Wang, A Zagariya, E Ang, O Ibarra-Sunga, B D Uha. Fas-induced apoptosis of alveolar epithelial cells requires ANG II generation and receptor interaction. The American journal of physiology. vol 277. issue 6. 2000-01-20. PMID:10600897. |
apoptosis in response to either fas activator was inhibited in a dose-dependent manner by the nonthiol ace inhibitor lisinopril or the nonselective ang ii receptor antagonist saralasin, with maximal inhibitions of 82 and 93% at doses of 0.5 and 5 microg/ml, respectively. |
2000-01-20 |
2023-08-12 |
human |
| R Wang, A Zagariya, O Ibarra-Sunga, C Gidea, E Ang, S Deshmukh, G Chaudhary, J Baraboutis, G Filippatos, B D Uha. Angiotensin II induces apoptosis in human and rat alveolar epithelial cells. The American journal of physiology. vol 276. issue 5. 1999-06-07. PMID:10330045. |
the nonthiol ace inhibitor lisinopril blocked apoptosis induced by angiotensinogen, but not apoptosis induced by purified ang ii. |
1999-06-07 |
2023-08-12 |
human |
| R Wang, A Zagariya, O Ibarra-Sunga, C Gidea, E Ang, S Deshmukh, G Chaudhary, J Baraboutis, G Filippatos, B D Uha. Angiotensin II induces apoptosis in human and rat alveolar epithelial cells. The American journal of physiology. vol 276. issue 5. 1999-06-07. PMID:10330045. |
these data demonstrate the presence of a functional ang ii-dependent pathway for apoptosis in human and rat aecs and suggest a role for the ang ii receptor and ace in the induction of aec apoptosis in vivo. |
1999-06-07 |
2023-08-12 |
human |
| A M Sharifi, E L Schiffri. Apoptosis in vasculature of spontaneously hypertensive rats: effect of an angiotensin converting enzyme inhibitor and a calcium channel antagonist. American journal of hypertension. vol 11. issue 9. 1998-11-24. PMID:9752897. |
therefore, we investigated the effect of the ace inhibitor enalapril and the dihydropyridine calcium channel blocker amlodipine on apoptosis in blood vessels of shr to determine whether part of the growth inhibitory effect of these drugs is mediated by apoptosis. |
1998-11-24 |
2023-08-12 |
human |
| A M Sharifi, E L Schiffri. Apoptosis in vasculature of spontaneously hypertensive rats: effect of an angiotensin converting enzyme inhibitor and a calcium channel antagonist. American journal of hypertension. vol 11. issue 9. 1998-11-24. PMID:9752897. |
antihypertensive agents such as the ace inhibitor enalapril and the calcium antagonist amlodipine may cause regression or inhibition of vascular wall growth in shr partly through enhanced apoptosis, which may contribute to the antihypertensive effects of these drugs. |
1998-11-24 |
2023-08-12 |
human |
| A Goussev, V G Sharov, H Shimoyama, M Tanimura, M Lesch, S Goldstein, H N Sabba. Effects of ACE inhibition on cardiomyocyte apoptosis in dogs with heart failure. The American journal of physiology. vol 275. issue 2. 1998-09-16. PMID:9683452. |
effects of ace inhibition on cardiomyocyte apoptosis in dogs with heart failure. |
1998-09-16 |
2023-08-12 |
human |
| A Goussev, V G Sharov, H Shimoyama, M Tanimura, M Lesch, S Goldstein, H N Sabba. Effects of ACE inhibition on cardiomyocyte apoptosis in dogs with heart failure. The American journal of physiology. vol 275. issue 2. 1998-09-16. PMID:9683452. |
we tested the hypothesis that early long-term monotherapy with an angiotensin-converting enzyme (ace) inhibitor attenuates cardiomyocyte apoptosis in dogs with moderate hf. |
1998-09-16 |
2023-08-12 |
human |
| A Goussev, V G Sharov, H Shimoyama, M Tanimura, M Lesch, S Goldstein, H N Sabba. Effects of ACE inhibition on cardiomyocyte apoptosis in dogs with heart failure. The American journal of physiology. vol 275. issue 2. 1998-09-16. PMID:9683452. |
attenuation of cardiomyocyte apoptosis may be one mechanism by which ace inhibitors preserve global lv function in hf. |
1998-09-16 |
2023-08-12 |
human |
| J Díez, A Panizo, M Hernández, F Vega, I Sola, M A Fortuño, J Pard. Cardiomyocyte apoptosis and cardiac angiotensin-converting enzyme in spontaneously hypertensive rats. Hypertension (Dallas, Tex. : 1979). vol 30. issue 5. 1997-12-10. PMID:9369251. |
in addition, we evaluated whether the development of cardiomyocyte apoptosis is related to blood pressure or to the activity of the local angiotensin-converting enzyme (ace) in shr. |
1997-12-10 |
2023-08-12 |
rat |
| J Díez, A Panizo, M Hernández, F Vega, I Sola, M A Fortuño, J Pard. Cardiomyocyte apoptosis and cardiac angiotensin-converting enzyme in spontaneously hypertensive rats. Hypertension (Dallas, Tex. : 1979). vol 30. issue 5. 1997-12-10. PMID:9369251. |
compared with 16-week-old normotensive wistar-kyoto rats, 16-week-old shr exhibited increased blood pressure (p<.001), increased rate of tetraploidy (p<.05), and similar levels of ace activity and apoptosis. |
1997-12-10 |
2023-08-12 |
rat |
| J Díez, A Panizo, M Hernández, F Vega, I Sola, M A Fortuño, J Pard. Cardiomyocyte apoptosis and cardiac angiotensin-converting enzyme in spontaneously hypertensive rats. Hypertension (Dallas, Tex. : 1979). vol 30. issue 5. 1997-12-10. PMID:9369251. |
compared with 30-week-old wistar-kyoto rats, 30-week-old shr showed increased blood pressure (p<.001), increased ace activity (p<.05), increased rate of tetraploidy (p<.01), and increased apoptosis (p<.01). |
1997-12-10 |
2023-08-12 |
rat |
| J Díez, A Panizo, M Hernández, F Vega, I Sola, M A Fortuño, J Pard. Cardiomyocyte apoptosis and cardiac angiotensin-converting enzyme in spontaneously hypertensive rats. Hypertension (Dallas, Tex. : 1979). vol 30. issue 5. 1997-12-10. PMID:9369251. |
untreated 30-week-old shr exhibited similar values of blood pressure and tetraploidy and higher ace activity (p<.05) and apoptosis (p<.001) than 16-week-old shr. |
1997-12-10 |
2023-08-12 |
rat |
| J Díez, A Panizo, M Hernández, F Vega, I Sola, M A Fortuño, J Pard. Cardiomyocyte apoptosis and cardiac angiotensin-converting enzyme in spontaneously hypertensive rats. Hypertension (Dallas, Tex. : 1979). vol 30. issue 5. 1997-12-10. PMID:9369251. |
the long-term administration of quinapril was associated with the normalization of ace activity and apoptosis in treated shr. |
1997-12-10 |
2023-08-12 |
rat |
| J Díez, A Panizo, M Hernández, F Vega, I Sola, M A Fortuño, J Pard. Cardiomyocyte apoptosis and cardiac angiotensin-converting enzyme in spontaneously hypertensive rats. Hypertension (Dallas, Tex. : 1979). vol 30. issue 5. 1997-12-10. PMID:9369251. |
whereas hypertrophy seems to be an earlier alteration that develops in parallel with hypertension, apoptosis develops later in association with overactivity of the local ace. |
1997-12-10 |
2023-08-12 |
rat |