| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Z Songyang, D Baltimore, L C Cantley, D R Kaplan, T F Frank. Interleukin 3-dependent survival by the Akt protein kinase. Proceedings of the National Academy of Sciences of the United States of America. vol 94. issue 21. 1997-11-24. PMID:9326612. |
overexpression of akt or oncogenic v-akt protects 32d cells from apoptosis induced by il-3 withdrawal. |
1997-11-24 |
2023-08-12 |
Not clear |
| Z Songyang, D Baltimore, L C Cantley, D R Kaplan, T F Frank. Interleukin 3-dependent survival by the Akt protein kinase. Proceedings of the National Academy of Sciences of the United States of America. vol 94. issue 21. 1997-11-24. PMID:9326612. |
apoptosis after il-3 withdrawal is accelerated by expression of dominant-negative mutants of akt, indicating that a functional akt signaling pathway is necessary for cell survival mediated by the cytokine il-3. |
1997-11-24 |
2023-08-12 |
Not clear |
| N N Ahmed, H L Grimes, A Bellacosa, T O Chan, P N Tsichli. Transduction of interleukin-2 antiapoptotic and proliferative signals via Akt protein kinase. Proceedings of the National Academy of Sciences of the United States of America. vol 94. issue 8. 1997-05-22. PMID:9108028. |
expression of catalytically active akt mutants in baf/3 cells expressing il-2r beta[a0]delta s promotes the expression of bcl-2 and c-myc, inhibits apoptosis induced by il-3 deprivation or staurosporine, and stimulates cell cycle progression. |
1997-05-22 |
2023-08-12 |
Not clear |
| S G Kennedy, A J Wagner, S D Conzen, J Jordán, A Bellacosa, P N Tsichlis, N Ha. The PI 3-kinase/Akt signaling pathway delivers an anti-apoptotic signal. Genes & development. vol 11. issue 6. 1997-05-02. PMID:9087425. |
we studied five downstream effectors of growth factor receptors--ras, raf, src, phosphoinositide 3-kinase (pi 3-kinase), and akt (pkb)--for their abilities to block apoptosis. |
1997-05-02 |
2023-08-12 |
Not clear |
| S G Kennedy, A J Wagner, S D Conzen, J Jordán, A Bellacosa, P N Tsichlis, N Ha. The PI 3-kinase/Akt signaling pathway delivers an anti-apoptotic signal. Genes & development. vol 11. issue 6. 1997-05-02. PMID:9087425. |
in contrast, inhibition of pi 3-kinase accelerated apoptosis, and an activated form of the serine/threonine kinase akt, a downstream effector of pi 3-kinase, blocked apoptosis. |
1997-05-02 |
2023-08-12 |
Not clear |
| G Kulik, A Klippel, M J Webe. Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt. Molecular and cellular biology. vol 17. issue 3. 1997-03-14. PMID:9032287. |
we found that membrane-targeted akt was sufficient to protect against apoptosis but that kinase-dead akt was not. |
1997-03-14 |
2023-08-12 |
Not clear |