| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Qing Wu, Yan Chen, Xinggang L. HDAC1 expression and effect of curcumin on proliferation of Raji cells. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban. vol 26. issue 2. 2008-05-12. PMID:16850746. |
this paper was designed to investigate the expression of hdac1 of raji cells and the effect of curcumin on their proliferation and apoptosis. |
2008-05-12 |
2023-08-12 |
Not clear |
| Qing Wu, Yan Chen, Xinggang L. HDAC1 expression and effect of curcumin on proliferation of Raji cells. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban. vol 26. issue 2. 2008-05-12. PMID:16850746. |
it is concluded that the expression of hdac1 plays an important role in the proliferation and apoptosis of raji cells and curcumin can inhibit the growth of raji cells at various concentrations and promote the apoptosis of raji cells. |
2008-05-12 |
2023-08-12 |
Not clear |
| Elona Biçaku, Douglas C Marchion, Morgen L Schmitt, Pamela N Münste. Selective inhibition of histone deacetylase 2 silences progesterone receptor-mediated signaling. Cancer research. vol 68. issue 5. 2008-04-08. PMID:18316616. |
selective inhibition of hdac2, but not hdac1 or hdac6, was sufficient to potentiate tamoxifen-induced apoptosis in er/pr-positive cells. |
2008-04-08 |
2023-08-12 |
Not clear |
| Qing Wu, Yan Chen, Xing-Gang Li, Yuan-Yan Tan. [Regulatory effect of curcumin on p300 and HDAC1 in B-NHL cells]. Zhongguo shi yan xue ye xue za zhi. vol 14. issue 2. 2007-12-14. PMID:16638200. |
the in vitro cultured raji cells were treated with curcumin at various concentrations (6.25-50 micromol/l) and at different time points (0, 6, 12, 24 and 48 hours), the inhibitory ratio of cell growth was measured by mtt assay, the cell apoptosis rate was detected by flow cytometry with annexin v-fitc/pi double staining, the changes of p300 and hdac1 mrna expression and protein level in raji cells were determined by rt-pcr and western blot. |
2007-12-14 |
2023-08-12 |
Not clear |
| Andre Fedier, Konstantin J Dedes, Patrick Imesch, Andre O Von Bueren, Daniel Fin. The histone deacetylase inhibitors suberoylanilide hydroxamic (Vorinostat) and valproic acid induce irreversible and MDR1-independent resistance in human colon cancer cells. International journal of oncology. vol 31. issue 3. 2007-11-30. PMID:17671692. |
furthermore, saha-induced resistance was not due to reduced apoptosis, and it was neither dependent on mdr expression nor was it due to increased expression of hdac1 and hdac3. |
2007-11-30 |
2023-08-12 |
human |
| Paulina Karwowska-Desaulniers, Anastasia Ketko, Nayana Kamath, Mary Kay H Pflu. Histone deacetylase 1 phosphorylation at S421 and S423 is constitutive in vivo, but dispensable in vitro. Biochemical and biophysical research communications. vol 361. issue 2. 2007-09-28. PMID:17643391. |
histone deacetylase 1 (hdac1) is a transcriptional regulator associated with proliferation, apoptosis, and tumorigenesis, although its precise cellular role is unclear. |
2007-09-28 |
2023-08-12 |
Not clear |
| Rusty L Montgomery, Christopher A Davis, Matthew J Potthoff, Michael Haberland, Jens Fielitz, Xiaoxia Qi, Joseph A Hill, James A Richardson, Eric N Olso. Histone deacetylases 1 and 2 redundantly regulate cardiac morphogenesis, growth, and contractility. Genes & development. vol 21. issue 14. 2007-09-05. PMID:17639084. |
whereas global deletion of hdac1 results in death by embryonic day 9.5, mice lacking hdac2 survive until the perinatal period, when they succumb to a spectrum of cardiac defects, including obliteration of the lumen of the right ventricle, excessive hyperplasia and apoptosis of cardiomyocytes, and bradycardia. |
2007-09-05 |
2023-08-12 |
mouse |
| Silvia Senese, Katrin Zaragoza, Simone Minardi, Ivan Muradore, Simona Ronzoni, Alfonso Passafaro, Loris Bernard, Giulio F Draetta, Myriam Alcalay, Christian Seiser, Susanna Chiocc. Role for histone deacetylase 1 in human tumor cell proliferation. Molecular and cellular biology. vol 27. issue 13. 2007-08-09. PMID:17470557. |
using gene expression profiling analysis, we found that inactivation of hdac1 affected the transcription of specific target genes involved in proliferation and apoptosis. |
2007-08-09 |
2023-08-12 |
mouse |
| Hisako Higashitsuji, Hiroaki Higashitsuji, Tomoko Masuda, Yu Liu, Katsuhiko Itoh, Jun Fujit. Enhanced deacetylation of p53 by the anti-apoptotic protein HSCO in association with histone deacetylase 1. The Journal of biological chemistry. vol 282. issue 18. 2007-06-14. PMID:17353187. |
thus, hsco is a cofactor that increases the deacetylase activity of hdac1 toward p53, leading to suppression of apoptosis. |
2007-06-14 |
2023-08-12 |
Not clear |
| Sung-Mi Kim, Hae-Jin Kee, Nakwon Choe, Ji-Young Kim, Hoon Kook, Hyun Kook, Sang-Beom Se. The histone methyltransferase activity of WHISTLE is important for the induction of apoptosis and HDAC1-mediated transcriptional repression. Experimental cell research. vol 313. issue 5. 2007-04-12. PMID:17239852. |
our results suggest that hmtase whistle induces apoptosis in an hmtase activity-dependent manner and represses transcription of target genes through hdac1 recruitment. |
2007-04-12 |
2023-08-12 |
Not clear |
| N Calonghi, E Pagnotta, C Parolin, C Molinari, C Boga, F Dal Piaz, G L Brusa, M A Santucci, L Masott. Modulation of apoptotic signalling by 9-hydroxystearic acid in osteosarcoma cells. Biochimica et biophysica acta. vol 1771. issue 2. 2007-04-03. PMID:17234448. |
in this paper our attention has not only been focused on hdac1 inhibition but also on the hyperacetylation of other substrates such as p53, that is involved in inducing cell cycle arrest and/or apoptosis, and whose activity and stability are known to be regulated by posttranslational modifications, particularly by acetylation at the c-terminus region. |
2007-04-03 |
2023-08-12 |
Not clear |
| Satoshi Inoue, Antonello Mai, Martin J S Dyer, Gerald M Cohe. Inhibition of histone deacetylase class I but not class II is critical for the sensitization of leukemic cells to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis. Cancer research. vol 66. issue 13. 2006-09-07. PMID:16818655. |
using different hdaci together with small interfering rna for hdac1, hdac2, hdac3, and hdac6, we report that inhibition of hdac1 and hdac2 but not hdac3, hdac6, and hdac8 are primarily responsible for sensitization to trail-induced apoptosis. |
2006-09-07 |
2023-08-12 |
Not clear |
| Ping Zhu, Evamaria Huber, Franz Kiefer, Martin Göttliche. Specific and redundant functions of histone deacetylases in regulation of cell cycle and apoptosis. Cell cycle (Georgetown, Tex.). vol 3. issue 10. 2006-04-24. PMID:15477762. |
thus, hdac2 appears to serve a preferential role in the prevention of apoptosis and not in cell cycle control similar to the specific importance of hdac1 for cell cycle regulation or hdac 9 for the stress response of the heart. |
2006-04-24 |
2023-08-12 |
Not clear |
| Ai-Guo Wang, Sun-Uk Kim, Sang Ho Lee, Sang-Keun Kim, Sang-Beom Seo, Dae-Yeul Yu, Dong-Seok Le. Histone deacetylase 1 contributes to cell cycle and apoptosis. Biological & pharmaceutical bulletin. vol 28. issue 10. 2006-02-07. PMID:16204956. |
to find out if the over-expression of hdac1 contributes to the expression of genes related to the cell cycle, apoptosis, and lipid metabolism that eventually contribute to the pathological changes in the livers of the transgenic mice, the expression profiles of the related genes in liver tissues were determined by reverse transcription-polymerase chain reaction (rt-pcr) and western blot analysis. |
2006-02-07 |
2023-08-12 |
mouse |
| Debdutta Bandyopadhyay, Anupam Mishra, Estela E Medran. Overexpression of histone deacetylase 1 confers resistance to sodium butyrate-mediated apoptosis in melanoma cells through a p53-mediated pathway. Cancer research. vol 64. issue 21. 2004-11-30. PMID:15520174. |
down-regulation of hdac1 by an antisense vector sensitized the cells to nab-induced apoptosis, whereas its overexpression conferred resistance to this agent. |
2004-11-30 |
2023-08-12 |
human |
| Hong Huang, Zhen-Xiang Zhang, Yong-Jian Xu, Jing-Fang Sha. [HDAC1 expression and effect of TSA on proliferation and apoptosis of A549 cells]. Ai zheng = Aizheng = Chinese journal of cancer. vol 22. issue 9. 2004-08-19. PMID:12969522. |
[hdac1 expression and effect of tsa on proliferation and apoptosis of a549 cells]. |
2004-08-19 |
2023-08-12 |
Not clear |
| Hong Huang, Zhen-Xiang Zhang, Yong-Jian Xu, Jing-Fang Sha. [HDAC1 expression and effect of TSA on proliferation and apoptosis of A549 cells]. Ai zheng = Aizheng = Chinese journal of cancer. vol 22. issue 9. 2004-08-19. PMID:12969522. |
this paper was designed to investigate the expression of hdac1 of a549 cell strains in hypoxia condition and the effect of tsa on their proliferation and apoptosis. |
2004-08-19 |
2023-08-12 |
Not clear |