| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C Paul, A P Arrig. Comparison of the protective activities generated by two survival proteins: Bcl-2 and Hsp27 in L929 murine fibroblasts exposed to menadione or staurosporine. Experimental gerontology. vol 35. issue 6-7. 2001-01-11. PMID:11053666. |
hence, despite some similar cellular effects resulting from their expression, bcl2 and hsp27 polypeptides protect against oxidative stress and apoptosis with different efficiencies and by using different mechanisms. |
2001-01-11 |
2023-08-12 |
Not clear |
| L F Cooper, J C Tiffee, J P Griffin, H Hamano, Z Gu. Estrogen-induced resistance to osteoblast apoptosis is associated with increased hsp27 expression. Journal of cellular physiology. vol 185. issue 3. 2000-12-13. PMID:11056010. |
estrogen-induced resistance to osteoblast apoptosis is associated with increased hsp27 expression. |
2000-12-13 |
2023-08-12 |
Not clear |
| L F Cooper, J C Tiffee, J P Griffin, H Hamano, Z Gu. Estrogen-induced resistance to osteoblast apoptosis is associated with increased hsp27 expression. Journal of cellular physiology. vol 185. issue 3. 2000-12-13. PMID:11056010. |
forced expression of hsp27 expression in other cell lines limits apoptosis. |
2000-12-13 |
2023-08-12 |
Not clear |
| L F Cooper, J C Tiffee, J P Griffin, H Hamano, Z Gu. Estrogen-induced resistance to osteoblast apoptosis is associated with increased hsp27 expression. Journal of cellular physiology. vol 185. issue 3. 2000-12-13. PMID:11056010. |
the purpose of this study was to examine the effects of estrogen on staurosporine-induced apoptosis in the context of hsp27 expression. |
2000-12-13 |
2023-08-12 |
Not clear |
| C Gao, Z Zou, L Xu, J Moul, P Seth, S Srivastav. p53-dependent induction of heat shock protein 27 (HSP27) expression. International journal of cancer. vol 88. issue 2. 2000-11-15. PMID:11004667. |
these observations provide evidence that induction of hsp27 expression was wild-type p53-specific and was not due to non-specific effects of cell growth arrest and/or apoptosis. |
2000-11-15 |
2023-08-12 |
Not clear |
| C Gao, Z Zou, L Xu, J Moul, P Seth, S Srivastav. p53-dependent induction of heat shock protein 27 (HSP27) expression. International journal of cancer. vol 88. issue 2. 2000-11-15. PMID:11004667. |
previous studies and the experiment reported here show induction of hsp27 expression in response to androgen ablation, a physiological state that induces apoptosis in prostatic epithelial cells. |
2000-11-15 |
2023-08-12 |
Not clear |
| C Gao, Z Zou, L Xu, J Moul, P Seth, S Srivastav. p53-dependent induction of heat shock protein 27 (HSP27) expression. International journal of cancer. vol 88. issue 2. 2000-11-15. PMID:11004667. |
the nature of p53 and hsp27 interactions in the regulation of apoptosis and/or cell growth needs to be further defined. |
2000-11-15 |
2023-08-12 |
Not clear |
| S J Charette, J N Lavoie, H Lambert, J Landr. Inhibition of Daxx-mediated apoptosis by heat shock protein 27. Molecular and cellular biology. vol 20. issue 20. 2000-10-30. PMID:11003656. |
heat shock protein 27 (hsp27) confers cellular protection against a variety of cytotoxic stresses and also against physiological stresses associated with growth arrest or receptor-mediated apoptosis. |
2000-10-30 |
2023-08-12 |
Not clear |
| S J Charette, J N Lavoie, H Lambert, J Landr. Inhibition of Daxx-mediated apoptosis by heat shock protein 27. Molecular and cellular biology. vol 20. issue 20. 2000-10-30. PMID:11003656. |
here we show that phosphorylated dimers of hsp27 interact with daxx, a mediator of fas-induced apoptosis, preventing the interaction of daxx with both ask1 and fas and blocking daxx-mediated apoptosis. |
2000-10-30 |
2023-08-12 |
Not clear |
| S J Charette, J N Lavoie, H Lambert, J Landr. Inhibition of Daxx-mediated apoptosis by heat shock protein 27. Molecular and cellular biology. vol 20. issue 20. 2000-10-30. PMID:11003656. |
no such inhibition was observed with an hsp27 phosphorylation mutant that is only expressed as oligomers or when apoptosis was induced by transfection of a daxx mutant lacking its hsp27 binding domain. |
2000-10-30 |
2023-08-12 |
Not clear |
| S J Charette, J N Lavoie, H Lambert, J Landr. Inhibition of Daxx-mediated apoptosis by heat shock protein 27. Molecular and cellular biology. vol 20. issue 20. 2000-10-30. PMID:11003656. |
hsp27 expression had no effect on fas-induced fadd- and caspase-dependent apoptosis. |
2000-10-30 |
2023-08-12 |
Not clear |
| S J Charette, J N Lavoie, H Lambert, J Landr. Inhibition of Daxx-mediated apoptosis by heat shock protein 27. Molecular and cellular biology. vol 20. issue 20. 2000-10-30. PMID:11003656. |
however, hsp27 blocked fas-induced translocation of daxx from the nucleus to the cytoplasm and fas-induced daxx- and ask1-dependent apoptosis. |
2000-10-30 |
2023-08-12 |
Not clear |
| D M Katschinski, K Boos, S G Schindler, J Fandre. Pivotal role of reactive oxygen species as intracellular mediators of hyperthermia-induced apoptosis. The Journal of biological chemistry. vol 275. issue 28. 2000-08-16. PMID:10781588. |
this differential induction of apoptosis was directly correlated to the induction of the antiapoptotic hsp27 and hsp70. |
2000-08-16 |
2023-08-12 |
Not clear |
| D M Katschinski, K Boos, S G Schindler, J Fandre. Pivotal role of reactive oxygen species as intracellular mediators of hyperthermia-induced apoptosis. The Journal of biological chemistry. vol 275. issue 28. 2000-08-16. PMID:10781588. |
in particular, in the hl-60 cells hsp27 was significantly induced at 12-18 h after exposure to 43 degrees c when apoptosis dropped. |
2000-08-16 |
2023-08-12 |
Not clear |
| D M Katschinski, K Boos, S G Schindler, J Fandre. Pivotal role of reactive oxygen species as intracellular mediators of hyperthermia-induced apoptosis. The Journal of biological chemistry. vol 275. issue 28. 2000-08-16. PMID:10781588. |
protection from ht-induced apoptosis as well as diminished heat-induced hsp27 expression was also observed after cotreatment of hl-60 cells with 43 degrees c and catalase but not with superoxide dismutase. |
2000-08-16 |
2023-08-12 |
Not clear |
| J Han, H Y Yoo, B H Choi, H M Rh. Selective transcriptional regulations in the human liver cell by hepatitis B viral X protein. Biochemical and biophysical research communications. vol 272. issue 2. 2000-07-10. PMID:10833446. |
two genes (igfr-2, rhoa) of oncogenes, one gene (p55cdc) of cell cycle regulators, three genes (thrombin receptor, mlk-3, macmarcks) of intracellular transducers, one gene (hsp27) of stress response proteins, two genes (fast kinase, bak) of apoptosis response proteins, one gene (p21(waf)) of transcription factors were highly up-regulated; one gene (transcription elongation factor sii) of transcription factors and two genes (monocyte chemotactic protein 1, t-lymphocyte-secreted protein i-309) of growth factors were highly down-regulated. |
2000-07-10 |
2023-08-12 |
human |
| G Tezel, M B Wa. The mechanisms of hsp27 antibody-mediated apoptosis in retinal neuronal cells. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 10. 2000-05-25. PMID:10804196. |
the mechanisms of hsp27 antibody-mediated apoptosis in retinal neuronal cells. |
2000-05-25 |
2023-08-12 |
human |
| G Tezel, M B Wa. The mechanisms of hsp27 antibody-mediated apoptosis in retinal neuronal cells. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 10. 2000-05-25. PMID:10804196. |
these results suggest that exogenous hsp27 antibody may induce neuronal apoptosis by inactivating or attenuating the ability of native hsp27 to stabilize actin cytoskeleton, thereby providing a novel mechanism by which autoantibodies to hsp27 may impair cell survival in selective human diseases. |
2000-05-25 |
2023-08-12 |
human |
| M R De Miglio, M R Muroni, M M Simile, D F Calvisi, P Tolu, L Deiana, A Carru, G Bonelli, F Feo, R M Pascal. Implication of Bcl-2 family genes in basal and D-amphetamine-induced apoptosis in preneoplastic and neoplastic rat liver lesions. Hepatology (Baltimore, Md.). vol 31. issue 4. 2000-04-19. PMID:10733553. |
hsp27 does not appear to sufficiently protect atypical lesions against apoptosis. |
2000-04-19 |
2023-08-12 |
rat |
| A T Hoang, J Huang, N Rudra-Ganguly, J Zheng, W C Powell, S K Rabindran, C Wu, P Roy-Burma. A novel association between the human heat shock transcription factor 1 (HSF1) and prostate adenocarcinoma. The American journal of pathology. vol 156. issue 3. 2000-03-23. PMID:10702402. |
these results document for the first time that hsf1 is overexpressed in human prostate cancer cells, at least one consequence of which in the prostate cancer cell lines tested is stimulation of both basal and stress-induced expression of hsp27, an important factor in cell growth, differentiation, or apoptosis. |
2000-03-23 |
2023-08-12 |
human |