| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Krishan Kumar, Shiv Govind Rawat, Manjit, Mohini Mishra, Priya, Ajay Kumar, Ruchi Chawl. Dual targeting pH responsive chitosan nanoparticles for enhanced active cellular internalization of gemcitabine in non-small cell lung cancer. International journal of biological macromolecules. 2023-07-31. PMID:37524283. |
in vitro cytotoxicity of nps quantified using cell based mtt, dapi and annexing-v/pi apoptosis assays showed superior antiproliferative activity of targeted nanoformulations (gmc-csn-sa-cxmab-nps ≫ gmc-csn-sa-nps, gmc-csn-cxmab-nps) over non-targeted nanoformulation (gmc-csn-nps) against a-549 cells. |
2023-07-31 |
2023-08-14 |
mouse |
| Mehrnoosh Pashei, Farahnaz Ghahremanfard, Ehsan Manouchehri Doulabi, Maral Hemmati, Fatemeh Pak, Parviz Kokhae. IL-25 Impact on Malignant B Cells Survival and T Cells Activation in Chronic Lymphocytic Leukemia. Iranian journal of allergy, asthma, and immunology. vol 22. issue 3. 2023-07-31. PMID:37524666. |
pbmcs and purified leukemic b cells were cultured with recombinant human il-25 (20ng/ml) for 72 hours, then the viability and apoptosis of cultured cells were measured by mtt assay and annexinv/7aad. |
2023-07-31 |
2023-08-14 |
human |
| Fatemeh Dodangeh, Zahra Sadeghi, Parichehr Maleki, Jamshid Rahe. Long non-coding RNA SOX2-OT enhances cancer biological traits via sponging to tumor suppressor miR-122-3p and miR-194-5p in non-small cell lung carcinoma. Scientific reports. vol 13. issue 1. 2023-07-31. PMID:37524903. |
downstream changes in cellular traits were assessed using mtt, flow cytometry, metastasis and apoptosis assays. |
2023-07-31 |
2023-08-14 |
Not clear |
| Rebai Ben Ammar, Hamad Abu Zahra, Abdulmalek Mohammad Abu Zahra, Manal Alfwuaires, Sarah Abdulaziz Alamer, Ashraf M Metwally, Thnaian A Althnaian, Saeed Y Al-Ramada. Protective Effect of Fucoxanthin on Zearalenone-Induced Hepatic Damage through Nrf2 Mediated by PI3K/AKT Signaling. Marine drugs. vol 21. issue 7. 2023-07-28. PMID:37504922. |
mtt assays, ros generation assays, western blots, and apoptosis analysis were used to evaluate the effects of fxn on zea-induced hepg2 cell inflammation. |
2023-07-28 |
2023-08-14 |
Not clear |
| Zhenzhao Dai, Jiansheng Hu, Zhiying Luo, Jianhua Xia. Downregulation of circ_0035292 Alleviates LPS-Induced WI-38 Cell Injury via Targeting miR-494-3p/TLR4 Pathway in Infantile Pneumonia. Biochemical genetics. 2023-07-27. PMID:37500967. |
cell proliferation and apoptosis were assessed by mtt assay, edu assay, and flow cytometry. |
2023-07-27 |
2023-08-14 |
Not clear |
| Jingwei Yan, Jingqing Yang, Huifen Shen, Rong Gao, Shilong L. Sinomenine regulates circTRPM7-related pathway to inhibit gastric cancer cell growth and metastasis. Chemical biology & drug design. 2023-07-26. PMID:37495546. |
mtt assay, colony formation assay, edu assay, transwell assay, wound-healing assay, and flow cytometry were used to detect cell proliferation, migration, invasion, and apoptosis. |
2023-07-26 |
2023-08-14 |
Not clear |
| Zahra Gholipour, Abbas Ali Imani Fooladi, Kazem Parivar, Raheleh Halabia. Targeting glioblastoma multiforme using a novel fusion protein comprising interleukin-13 and staphylococcal enterotoxin B in vitro. Toxicology in vitro : an international journal published in association with BIBRA. 2023-07-23. PMID:37482138. |
the fusion protein was cloned into pet28a(+) and expressed in escherichia coli strain bl21 (de3); u251 (il13rα2-positive) and t98g (il13rα2-negative) gbm cell lines were employed and the functional activity of il13-linker-seb was evaluated by cell elisa, cytotoxicity (mtt and ldh), apoptosis (flow cytometry and caspase-3 activity), adhesion, scratch and rt-pcr tests. |
2023-07-23 |
2023-08-14 |
human |
| Sana Abbasi, Helia Rivand, Fatemeh Eshaghi, Mohammad Amin Moosavi, Saeid Amanpour, Michael F McDermott, Marveh Rahmat. Inhibition of IRE1 RNase activity modulates tumor cell progression and enhances the response to chemotherapy in colorectal cancer. Medical oncology (Northwood, London, England). vol 40. issue 9. 2023-07-22. PMID:37480455. |
an mtt assay, flow cytometry and rt-pcr were performed to determine cell growth, apoptosis and ire1α activity, respectively. |
2023-07-22 |
2023-08-14 |
mouse |
| Xiaoqi Ma, Midie Xu, Xing Zhang, Xin Wang, Kexin Su, Zihang Xu, Xiaoyu Wang, Yifu Yan. Gambogenic acid inhibits proliferation and ferroptosis by targeting the miR-1291/FOXA2 and AMPKα/SLC7A11/GPX4 axis in colorectal cancer. Cell biology international. 2023-07-20. PMID:37471707. |
the present study aims to investigate the mechanism of the nature compound gambogenic acid (gna) on the apoptosis and ferroptosis in colorectal cancer (crc). the effect of gna on the proliferation of crc cell lines were detected by mtt and clonogenic assay. |
2023-07-20 |
2023-08-14 |
Not clear |
| Hanife Yuksel Cakmak, Hasan Ege, Senanur Yilmaz, Gokhan Agturk, Fulya Dal Yontem, Gozde Enguven, Abdurrahman Sarmis, Zeren Cakmak, Oguzhan Gunduz, Zeynep Ruya Eg. 3D printed Styrax Liquidus (Liquidambar orientalis Miller)-loaded poly (L-lactic acid)/chitosan based wound dressing material: Fabrication, characterization, and biocompatibility results. International journal of biological macromolecules. 2023-07-20. PMID:37473890. |
annexin v/pi double stain assay was performed to test whether early or late apoptosis was induced in the pla/cs/1 % st and pla/cs/2 % st loaded groups and the results were consistent with the mtt assay. |
2023-07-20 |
2023-08-14 |
human |
| Jing He, Xiaoxiang Xi, Peng Cao, Jinxia Zhou, Hui Liu, Na L. Long non-coding RNA GNAS-AS1 knockdown inhibits proliferation and epithelial-mesenchymal transition of lung adenocarcinoma cells via the microRNA-433-3p/Rab3A axis. Open medicine (Warsaw, Poland). vol 18. issue 1. 2023-07-19. PMID:37465347. |
cell proliferation and apoptosis were checked using mtt and flow cytometry, respectively. |
2023-07-19 |
2023-08-14 |
Not clear |
| Rui Tian, Huixin Li, Songjie Ren, Shukui Li, Run Fang, Yang Li. circRNA THBS1 silencing inhibits the malignant biological behavior of cervical cancer cells via the regulation of miR-543/HMGB2 axis. Open medicine (Warsaw, Poland). vol 18. issue 1. 2023-07-19. PMID:37465349. |
cell proliferation and apoptosis were evaluated by mtt and flow cytometry, respectively. |
2023-07-19 |
2023-08-14 |
Not clear |
| Hui Li, Jian Hao, Weimin Y. LncRNA CASC15 inhibition relieves renal fibrosis in diabetic nephropathy through down-regulating SP-A by sponging to miR-424. Open medicine (Warsaw, Poland). vol 18. issue 1. 2023-07-19. PMID:37465354. |
mtt and flow cytometry analysis were carried out to test cell proliferation and apoptosis. |
2023-07-19 |
2023-08-14 |
Not clear |
| Sasenka Vidicevic-Novakovic, Zeljka Stanojevic, Nina Tomonjic, Katarina Karapandza, Janko Zekovic, Tamara Martinovic, Danica Grujicic, Rosanda Ilic, Savo Raicevic, Jelena Tasic, Aleksandra Isakovi. Proapoptotic and proautophagy effect of H1-receptor antagonist desloratadine in human glioblastoma cell lines. Medical oncology (Northwood, London, England). vol 40. issue 8. 2023-07-16. PMID:37452991. |
cytotoxic effect of desloratadine was investigated using mtt and cv assays, while oxidative stress, apoptosis, and autophagy were detected by flow cytometry and immunoblot. |
2023-07-16 |
2023-08-14 |
human |
| Claudia Felici, Anna Passarelli, Paola Cafforio, Vito Racanelli, Patrizia Leone, Marco Tucc. Lenalidomide arrests cell cycle and modulates PD1-dependent downstream mTOR intracellular signals in melanoma cells. Melanoma research. 2023-07-14. PMID:37451673. |
the antiproliferative action of lenalidomide was evaluated on two melanoma cell lines by mtt assay, cell cycle and apoptosis assay. |
2023-07-14 |
2023-08-14 |
Not clear |
| Jinling Qiao, Huizhi Ma, Meirong Chen, Jie Ba. Vitamin D alleviates neuronal injury in cerebral ischemia-reperfusion via enhancing the Nrf2/HO-1 antioxidant pathway to counteract NLRP3-mediated pyroptosis. Journal of neuropathology and experimental neurology. 2023-07-05. PMID:37403613. |
administration of 1,25-vitd3 improved cell viability and inhibited lactate dehydrogenase (ldh) activity and cell apoptosis in ogd/r-stimulated rn-c, as assessed by 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2-h-tetrazolium bromide (mtt) assay, ldh activity assays and tdt-mediated dutp nick end labeling (tunel) staining, respectively. |
2023-07-05 |
2023-08-14 |
rat |
| Qing Tian, Ying Guo, Jinfeng Liu, Chao Pang, Qiang Wang, Qi Xie, Jianke L. CircDUS2L (circ_0039908) promotes lung adenocarcinoma progression by upregulating PGAM1 by acting as a miR-590-5p molecular sponge. Journal of biochemical and molecular toxicology. 2023-07-01. PMID:37392398. |
cell proliferation, apoptosis, metastasis, and invasion were assessed by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt), colony formation, 5-ethynyl-2'-deoxyuridine (edu), flow cytometry, and transwell assays. |
2023-07-01 |
2023-08-14 |
Not clear |
| GuangDuo Zhu, XiaoWei Yang, WeiWei Zhou, Xu Lian, YingJie Ha. PLAGL2 induces nucleus pulposus cell apoptosis via regulating RASSF5 expression and thus accelerates intervertebral disc degeneration. Experimental cell research. 2023-06-26. PMID:37364764. |
the impact of plagl2 on the viability, apoptosis, and mitochondria function of np cells was evaluated by mtt assay, tunel, jc1 staining, and flow cytometry assay. |
2023-06-26 |
2023-08-14 |
mouse |
| Hosein Esmaeili, Mehrdad Nasrollahzadeh Sabet, Reza Mosaed, Mohsen Chamanara, Saeid Hadi, Ebrahim Hazrati, Arezoo Farhadi, Mohammad Foad Heidari, Javad Behrooz. Oleanolic acid increases the anticancer potency of doxorubicin in pancreatic cancer cells. Journal of biochemical and molecular toxicology. 2023-06-22. PMID:37345903. |
therefore, we investigated the efficacy of combination therapy by widely used chemotherapy drug doxorubicin (dox) and oleanolic acid (oa) to induction of apoptosis for pancreatic cancer (pc) therapy. the effects of dox, oa, and their combination (dox-oa) were investigated on proliferation and viability of pc cell line (panc-1) by mtt assay. |
2023-06-22 |
2023-08-14 |
Not clear |
| Feng Wang, Ma-ChiCheng Bao, Jing Xu, Lan-Lan Shi, Rui-Ze Niu, Ting-Hua Wang, Jia Li. Scutellarin inhibits the glioma cell proliferation by downregulating BIRC5 to promote cell apoptosis. Journal of cellular and molecular medicine. 2023-06-21. PMID:37340587. |
the wound healing assay, flow cytometry and mtt test were used to detect the effect of scutellarin on the apoptosis and proliferation of glioma cells. |
2023-06-21 |
2023-08-14 |
mouse |