| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Juan Fu, Zhi Dang, Yan Deng, Guining L. Regulation of c-Myc and Bcl-2 induced apoptosis of human bronchial epithelial cells by zinc oxide nanoparticles. Journal of biomedical nanotechnology. vol 8. issue 4. 2012-11-01. PMID:22852476. |
to explore the possible molecular mechanisms for apoptosis induced by zno nps, we investigated the relevant apoptotic signaling in human bronchial epithelial (16hbe) cells. |
2012-11-01 |
2023-08-12 |
human |
| Juan Fu, Zhi Dang, Yan Deng, Guining L. Regulation of c-Myc and Bcl-2 induced apoptosis of human bronchial epithelial cells by zinc oxide nanoparticles. Journal of biomedical nanotechnology. vol 8. issue 4. 2012-11-01. PMID:22852476. |
our results suggested that apoptosis induced by zno nps might primarily involve the regulations of c-myc and bcl-2 gene expressions besides decline of mmp in 16hbe cells. |
2012-11-01 |
2023-08-12 |
human |
| Xuezi Sang, Lei Zheng, Qingqing Sun, Na Li, Yaling Cui, Renping Hu, Guodong Gao, Zhe Cheng, Jie Cheng, Suxin Gui, Huiting Liu, Zengli Zhang, Fashui Hon. The chronic spleen injury of mice following long-term exposure to titanium dioxide nanoparticles. Journal of biomedical materials research. Part A. vol 100. issue 4. 2012-08-28. PMID:22275130. |
our findings indicate that tio(2) nps exposure results in the significant increase in the spleen indices, histopathological changes, and splenocyte apoptosis in spleen. |
2012-08-28 |
2023-08-12 |
mouse |
| Emmanuelle Huillard, Rintaro Hashizume, Joanna J Phillips, Amélie Griveau, Rebecca A Ihrie, Yasuyuki Aoki, Theodore Nicolaides, Arie Perry, Todd Waldman, Martin McMahon, William A Weiss, Claudia Petritsch, C David James, David H Rowitc. Cooperative interactions of BRAFV600E kinase and CDKN2A locus deficiency in pediatric malignant astrocytoma as a basis for rational therapy. Proceedings of the National Academy of Sciences of the United States of America. vol 109. issue 22. 2012-08-24. PMID:22586120. |
here we report that braf(v600e) expression in neural progenitors (nps) is insufficient for tumorigenesis and increases np cellular differentiation as well as apoptosis. |
2012-08-24 |
2023-08-12 |
mouse |
| Saied Soflaei, Abdolhossein Dalimi, Fatemeh Ghaffarifar, Mojtaba Shakibaie, Ahmad Reza Shahverdi, Mohsen Shafiepou. In Vitro Antiparasitic and Apoptotic Effects of Antimony Sulfide Nanoparticles on Leishmania infantum. Journal of parasitology research. vol 2012. 2012-08-23. PMID:22792443. |
on the other hand, however, antimony sulfide nps have a low cytotoxicity effect on uninfected macrophages but it can induce apoptosis in promastigote stage at 3 of 4 concentrations. |
2012-08-23 |
2023-08-12 |
Not clear |
| Zhengli Xu, Laisheng Chou, Jiao Su. Effects of SiO2 nanoparticles on HFL-I activating ROS-mediated apoptosis via p53 pathway. Journal of applied toxicology : JAT. vol 32. issue 5. 2012-07-23. PMID:21766316. |
these findings implied that sio(2) nps might induce apoptosis of hfl-is by stimulating reactive oxygen species release and subsequently causing the activation of p53 pathway in vitro. |
2012-07-23 |
2023-08-12 |
human |
| Maqsood A Siddiqui, Maqusood Ahamed, Javed Ahmad, M A Majeed Khan, Javed Musarrat, Abdulaziz A Al-Khedhairy, Salman A Alrokaya. Nickel oxide nanoparticles induce cytotoxicity, oxidative stress and apoptosis in cultured human cells that is abrogated by the dietary antioxidant curcumin. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 50. issue 3-4. 2012-07-16. PMID:22273695. |
this study was designed to investigate nio nps induced cytotoxicity, oxidative stress and apoptosis in cultured human airway epithelial (hep-2) and human breast cancer (mcf-7) cells. |
2012-07-16 |
2023-08-12 |
human |
| Maqsood A Siddiqui, Maqusood Ahamed, Javed Ahmad, M A Majeed Khan, Javed Musarrat, Abdulaziz A Al-Khedhairy, Salman A Alrokaya. Nickel oxide nanoparticles induce cytotoxicity, oxidative stress and apoptosis in cultured human cells that is abrogated by the dietary antioxidant curcumin. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 50. issue 3-4. 2012-07-16. PMID:22273695. |
induction of caspase-3 enzyme activity and dna fragmentation, biomarkers of apoptosis were also observed in nio nps exposed cells. |
2012-07-16 |
2023-08-12 |
human |
| Maqsood A Siddiqui, Maqusood Ahamed, Javed Ahmad, M A Majeed Khan, Javed Musarrat, Abdulaziz A Al-Khedhairy, Salman A Alrokaya. Nickel oxide nanoparticles induce cytotoxicity, oxidative stress and apoptosis in cultured human cells that is abrogated by the dietary antioxidant curcumin. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 50. issue 3-4. 2012-07-16. PMID:22273695. |
this is the first report showing that nio nps induced ros mediated cytotoxicity and apoptosis that is abrogated by curcumin. |
2012-07-16 |
2023-08-12 |
human |
| Wen Gao, Lifei Ji, Lu Li, Guanwei Cui, Kehua Xu, Ping Li, Bo Tan. Bifunctional combined Au-Fe(2)O(3) nanoparticles for induction of cancer cell-specific apoptosis and real-time imaging. Biomaterials. vol 33. issue 14. 2012-07-10. PMID:22342711. |
we demonstrate bifunctional combined au-fe(2)o(3) nanoparticles (nps) for selectively induction of apoptosis in cancer cells and real-time imaging. |
2012-07-10 |
2023-08-12 |
human |
| Wen Gao, Lifei Ji, Lu Li, Guanwei Cui, Kehua Xu, Ping Li, Bo Tan. Bifunctional combined Au-Fe(2)O(3) nanoparticles for induction of cancer cell-specific apoptosis and real-time imaging. Biomaterials. vol 33. issue 14. 2012-07-10. PMID:22342711. |
conjugated with α(Ⅴ)β(3) integrin-targeting peptide (rgd) and fluorescein isothiocyanate (fitc)-labeled capsase-3 recognition sequence (devd) on the au surface, the resulting rgd/fitc-devd-au-fe(2)o(3) nps bind preferentially to integrin α(Ⅴ)β(3)-rich human liver cancer cells (hepg2), sequentially initiate catalytic formation of hydroxyl radicals (·oh) and enable the real-time monitoring of·oh-induced caspase-3-dependent apoptosis in these cancer cells. |
2012-07-10 |
2023-08-12 |
human |
| Sang Kyoon Kim, Michael B Foote, Leaf Huan. The targeted intracellular delivery of cytochrome C protein to tumors using lipid-apolipoprotein nanoparticles. Biomaterials. vol 33. issue 15. 2012-07-05. PMID:22365810. |
nps were produced with either gfp, a fluorescent model protein, or cytochrome c (cytc), an inducer of apoptosis in cancer cells. |
2012-07-05 |
2023-08-12 |
mouse |
| Hao Yu, Yue Zh. Expression of ADAMTS-7 and ADAMTS-12 in the nucleus pulposus during degeneration of rat caudal intervetebral disc. The Journal of veterinary medical science. vol 74. issue 1. 2012-06-12. PMID:21869572. |
the discs were loaded for one week, and and the nuclei pulposi (nps) were harvested to investigate cell apoptosis and expression of collagen ii and aggrecan for confirmation of disc degeneration. |
2012-06-12 |
2023-08-12 |
rat |
| Lun Li, Jie Sun, Xiaoran Li, Yan Zhang, Zhaoxu Wang, Chunren Wang, Jianwu Dai, Qiangbin Wan. Controllable synthesis of monodispersed silver nanoparticles as standards for quantitative assessment of their cytotoxicity. Biomaterials. vol 33. issue 6. 2012-04-19. PMID:22137123. |
with the monodispersed ag nps as standard samples, the size- and dose- dependent cytotoxicity of ag nps against human lung fibroblast (hlf) cells was accurately accomplished in terms of cell viability, apoptosis and necrosis, reactive oxygen species, etc. |
2012-04-19 |
2023-08-12 |
human |
| Kyle Meyer, Pavan Rajanahalli, Maqusood Ahamed, John J Rowe, Yiling Hon. ZnO nanoparticles induce apoptosis in human dermal fibroblasts via p53 and p38 pathways. Toxicology in vitro : an international journal published in association with BIBRA. vol 25. issue 8. 2012-04-13. PMID:21903158. |
this study was designed to investigate the apoptosis induction by zno nps via mitogen-activated protein kinase p38 and cell cycle checkpoint protein p53 pathways in human dermal fibroblasts. |
2012-04-13 |
2023-08-12 |
human |
| Kyle Meyer, Pavan Rajanahalli, Maqusood Ahamed, John J Rowe, Yiling Hon. ZnO nanoparticles induce apoptosis in human dermal fibroblasts via p53 and p38 pathways. Toxicology in vitro : an international journal published in association with BIBRA. vol 25. issue 8. 2012-04-13. PMID:21903158. |
our results suggest that zno nps have the potential to induce apoptosis in human dermal fibroblasts via p53-p38 pathways. |
2012-04-13 |
2023-08-12 |
human |
| Soukaina Réjiba, L Harivardhan Reddy, Christelle Bigand, Céline Parmentier, Patrick Couvreur, Amor Hajr. Squalenoyl gemcitabine nanomedicine overcomes the low efficacy of gemcitabine therapy in pancreatic cancer. Nanomedicine : nanotechnology, biology, and medicine. vol 7. issue 6. 2012-03-13. PMID:21419876. |
cell viability and apoptosis assays showed that sq-gem nps displayed higher antiproliferative and cytotoxic effects, particularly in chemoresistant panc1 tumor cells. |
2012-03-13 |
2023-08-12 |
mouse |
| Geetanjali Arya, Mallaredy Vandana, Sarbari Acharya, Sanjeeb K Saho. Enhanced antiproliferative activity of Herceptin (HER2)-conjugated gemcitabine-loaded chitosan nanoparticle in pancreatic cancer therapy. Nanomedicine : nanotechnology, biology, and medicine. vol 7. issue 6. 2012-03-13. PMID:21550422. |
the targeted nps displayed superior antiproliferative activity along with an enhanced s-phase arrest, leading to apoptosis in comparison with unconjugated gemcitabine-loaded nanoparticles and free gemcitabine due to higher cellular binding with eventual uptake and prolonged intracellular retention. |
2012-03-13 |
2023-08-12 |
Not clear |
| Gen Zhang, Bin Bin Lai, Yan Yan Zhou, Bao An Chen, Xue Mei Wang, Qun Lu, Yan-Hua Che. Fe3O4 nanoparticles with daunorubicin induce apoptosis through caspase 8-PARP pathway and inhibit K562 leukemia cell-induced tumor growth in vivo. Nanomedicine : nanotechnology, biology, and medicine. vol 7. issue 5. 2012-02-03. PMID:21333751. |
here we investigate the synergistic effects of fe(3)o(4) nps with dnr on the induction of apoptosis using k562 leukemia cells. |
2012-02-03 |
2023-08-12 |
mouse |
| Gen Zhang, Bin Bin Lai, Yan Yan Zhou, Bao An Chen, Xue Mei Wang, Qun Lu, Yan-Hua Che. Fe3O4 nanoparticles with daunorubicin induce apoptosis through caspase 8-PARP pathway and inhibit K562 leukemia cell-induced tumor growth in vivo. Nanomedicine : nanotechnology, biology, and medicine. vol 7. issue 5. 2012-02-03. PMID:21333751. |
fe(3)o(4) nps increased the ability of dnr to induce apoptosis in both adriamycin-sensitive and adriamycin-resistant k562 cells through the caspase 8-poly(adp-ribose) polymerase pathway. |
2012-02-03 |
2023-08-12 |
mouse |