| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hui Shao, Jingyan Chen, Ali Li, Lili Ma, Yongzhi Tang, Huazhong Chen, Yongping Chen, Junyan Li. Salvigenin Suppresses Hepatocellular Carcinoma Glycolysis and Chemoresistance Through Inactivating the PI3K/AKT/GSK-3β Pathway. Applied biochemistry and biotechnology. 2023-05-02. PMID:37129745. |
in-vivo assay revealed that salvigenin hampered the growth and promoted apoptosis of hcc cells in nude mice. |
2023-05-02 |
2023-08-14 |
mouse |
| Haoying Huang, Xiaohan Yi, Qingyun Wei, Mengyuan Li, Xueting Cai, Yan Lv, Ling Weng, Yujie Mao, Weiwei Fan, Mengmeng Zhao, Zhongpei Weng, Qing Zhao, Kewei Zhao, Meng Cao, Jing Chen, Peng Ca. Edible and cation-free kiwi fruit derived vesicles mediated EGFR-targeted siRNA delivery to inhibit multidrug resistant lung cancer. Journal of nanobiotechnology. vol 21. issue 1. 2023-02-05. PMID:36740689. |
intriguingly, the systemic administration of stat3/ekevs significantly suppressed subcutaneous pc9-gr4-azd1 tumor xenografts in nude mice by stat3 mediated apoptosis. |
2023-02-05 |
2023-08-14 |
mouse |
| Xiaodong Li, Ying Wang, Baoying Zhang, Rui Mao, Zhongkui Wang, Tingyu Jiang, Haibin Son. Hsa_circ_0119412 Contributes to Development of Retinoblastoma by Targeting miR-186-5p/ELK4 Axis. Molecular biotechnology. 2023-01-30. PMID:36715861. |
in vitro assay revealed that downregulating circ_0119412 accelerated the cell apoptosis of rb cells and slowed down their migration and proliferation, and the in vivo assay indicated that circ_0119412 downregulation reduced the weight and volume of tumor in nude mice. |
2023-01-30 |
2023-08-14 |
mouse |
| Weihui Yu, Ke Ning, Jincheng Xiao, Qiwen Bai, Chenyang Gu. Hsa_circ_0007380 silencing restrains the growth and enhances radiosensitivity in esophagus cancer by miR-644a/Spindlin 1 axis. Anti-cancer drugs. vol 34. issue 1. 2022-12-20. PMID:36539369. |
hsa_circ_0007380 was highly expressed in esophagus cancer tissues and cells, knockdown of hsa_circ_0007380 suppressed esophagus cancer cell proliferation, induced apoptosis and enhanced radiosensitivity in vitro, and the same effects were also confirmed in nude mice. |
2022-12-20 |
2023-08-14 |
mouse |
| Anil Kumar Kalvala, Ramesh Nimma, Arvind Bagde, Sunil Kumar Surapaneni, Nilkumar Patel, Peggy Arthur, Li Sun, Rakesh Singh, Nagavendra Kommineni, Aakash Nathani, Yan Li, Mandip Sing. The role of Cannabidiol and tetrahydrocannabivarin to overcome doxorubicin resistance in MDA-MB-231 xenografts in athymic nude mice. Biochimie. 2022-12-19. PMID:36535544. |
transcriptomics and proteomics studies revealed that cbd and thcv, by downregulating pd-l1, tgf-β, sp1, nlrp3, p38-mapk, and upregulating ampk induced apoptosis leading to improved dox's chemosensitivity against dox resistant mda-mb-231 tumors in balb/c nude mice. |
2022-12-19 |
2023-08-14 |
mouse |
| Yang Yang, Xiaoli Zheng, Peizan Ni, Dingjie Li, Qinfu Dan, Xiaohui Wang, Yunhan Wang, Yanan Sun, Kangdong Liu, Zigang Dong, Hong G. Targeting the STAT5A/IDO1 axis overcomes radioresistance and reverses the immunosuppressive tumor microenvironment in NSCLC. International journal of oncology. vol 62. issue 1. 2022-12-01. PMID:36453241. |
mtt assay, immunofluorescence, apoptosis analysis, cell cycle analysis, and c57bl/6 and balb/c nude mouse tumor models were utilized to evaluate the roles of the stat5a/ido1/kynurenine axis in radioresistance and in the immune microenvironment of nsclc. |
2022-12-01 |
2023-08-14 |
mouse |
| Huijuan Zhang, Mingxia Li, Huiru Sun, Wen Yang, Mingxia Ye, Hua Li, Yuanguang Men. 4SC-202 exerts an anti-tumor effect in cervical cancer by targeting PRLR signaling pathway. Journal of molecular histology. 2022-10-22. PMID:36272045. |
a xenograft tumor model in nude mice was established to examine effects of 4sc-202 on the tumor growth, apoptosis and prlr-related pathways in vivo. |
2022-10-22 |
2023-08-14 |
mouse |
| Ya-Jun Hou, Dawei Li, Weiqi Wang, Leilei Mao, Xiaoyan Fu, Baoliang Sun, Cundong Fa. NT157 inhibits cell proliferation and sensitizes glioma cells to TRAIL-induced apoptosis by up-regulating DR5 expression. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 153. 2022-09-09. PMID:36076591. |
importantly, combined administration of nt157 and trail in vivo effectively inhibited glioma xenograft growth of nude mice by inhibiting cell proliferation and angiogenesis, and inducing dna damage and apoptosis. |
2022-09-09 |
2023-08-14 |
mouse |
| Chien-Teng Lin, Chuen-Fu Lin, Jui-Te Wu, Hsiao-Pei Tsai, Shu-Ying Cheng, Huei-Jyuan Liao, Tzu-Chun Lin, Chao-Hsuan Wu, Yu-Chin Lin, Jiann-Hsiung Wang, Geng-Ruei Chan. Effects of Para-Toluenesulfonamide on Canine Melanoma Xenotransplants in a BALB/c Nude Mouse Model. Animals : an open access journal from MDPI. vol 12. issue 17. 2022-09-09. PMID:36077992. |
we aimed to examine the antitumor effect of pts or pts combined with cisplatin on canine melanoma implanted in balb/c nude mice by estimating tumor growth, apoptosis expression, inflammation, and metastasis. |
2022-09-09 |
2023-08-14 |
mouse |
| Lixia Chen, Jinshuai Lan, Zhe Li, Ruifeng Zeng, Yu Wang, Lu Zhen, Haojieyin Jin, Yue Ding, Tong Zhan. A Novel Diosgenin-Based Liposome Delivery System Combined with Doxorubicin for Liver Cancer Therapy. Pharmaceutics. vol 14. issue 8. 2022-08-26. PMID:36015311. |
compared with commercial dox liposome (chol-dox-lp), dios-dox-lp had an improved anti-tumor effect in vitro and in vivo by inducing the apoptosis and inhibiting the proliferation of the tumor cell, which was 1.6 times better than chol-dox-lp in cytotoxicity, and had 78% of the tumor inhibition rate on tumor-bearing nude mice. |
2022-08-26 |
2023-08-14 |
mouse |
| Peiyuan Li, Weisheng Xia. Circ_0005758 impedes gastric cancer progression through miR-1229-3p/GCNT4 feedback loop. Toxicology in vitro : an international journal published in association with BIBRA. 2022-08-15. PMID:35970245. |
circ_0005758 expression was decreased in gc tissues and cells, re-expression of circ_0005758 induced apoptosis and suppressed proliferation, migration, invasion and angiogenesis in gc cells in vitro, and impeded xenograft tumor growth in nude mice. |
2022-08-15 |
2023-08-14 |
mouse |
| Ruijun Liu, Ruili Liu, Zhiyi Guo, Jianghao Ren, Jia Huang, Qingquan Luo, Qiang Ta. shRNA‑mediated knockdown of KNTC1 inhibits non-small-cell lung cancer through regulating PSMB8. Cell death & disease. vol 13. issue 8. 2022-08-06. PMID:35933405. |
the effects of kntc1 depletion on nsclc cell proliferation, migration, apoptosis, and tumor formation were analyzed by mtt assay, wound-healing assay, transwell assay, flow cytometry assay, and in nude mouse models in vivo. |
2022-08-06 |
2023-08-14 |
mouse |
| Feng Xue, Min Li, Yun Liu, Chunxin Xu, Haigang Li, Huilian Li. Circ_0035381 Regulates Acute Myeloid Leukemia Development by Modulating YWHAZ Expression via Adsorbing miR-582-3p. Biochemical genetics. 2022-08-02. PMID:35917008. |
circ_0035381 downregulation decreased aml cell growth in nude mice and restrained aml cell proliferation and contributed to aml apoptosis and mitochondrial damage in vitro. |
2022-08-02 |
2023-08-14 |
mouse |
| Feng Luo, Jinbang Li, Jihong Liu, Kunping Li. Stabilizing and upregulating Axin with tankyrase inhibitor reverses 5-fluorouracil chemoresistance and proliferation by targeting the WNT/caveolin-1 axis in colorectal cancer cells. Cancer gene therapy. 2022-06-24. PMID:35750753. |
the effect and mechanism of xav939 on proliferation and apoptosis induced by 5-fu in xenograft tumors of nude mice were evaluated by immunohistochemistry and tunel staining. |
2022-06-24 |
2023-08-14 |
mouse |
| Fei-Hong Ji, Xing-Hao Fu, Guo-Quan Li, Qi He, Xin-Guang Qi. FTO Prevents Thyroid Cancer Progression by SLC7A11 m6A Methylation in a Ferroptosis-Dependent Manner. Frontiers in endocrinology. vol 13. 2022-06-20. PMID:35721711. |
the role of fto in ptc was assessed by cell counting kit-8 analysis, cell scratch, migration, invasion experiment, flow cytometry apoptosis analysis, and nude mouse experiment. |
2022-06-20 |
2023-08-14 |
mouse |
| Yan Xu, Jingqi Qi, Wei Sun, Wu Zhong, Hongwei W. Therapeutic Effects of Zoledronic Acid-Loaded Hyaluronic Acid/Polyethylene Glycol/Nano-Hydroxyapatite Nanoparticles on Osteosarcoma. Frontiers in bioengineering and biotechnology. vol 10. 2022-06-13. PMID:35694235. |
in the orthotopic osteosarcoma nude mice model, local injection of the ha-peg-nha-zol nps stimulated tumor necrosis, apoptosis, and granulocyte infiltration in the blood vessels. |
2022-06-13 |
2023-08-14 |
mouse |
| Ching-Feng Wu, Ching-Yang Wu, Chuen-Fu Lin, Yi-Wen Liu, Tzu-Chun Lin, Huei-Jyuan Liao, Geng-Ruei Chan. The anticancer effects of cyanidin 3-O-glucoside combined with 5-fluorouracil on lung large-cell carcinoma in nude mice. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 151. 2022-05-24. PMID:35609368. |
we determined the tumor growth, apoptosis, inflammation, and metastasis in the h661 lung lcc lines xenografted into balb/c nude mice. |
2022-05-24 |
2023-08-13 |
mouse |
| Xiaofeng Li, Wen Lu, Tianjiao Zhou, Feng Zhao, Li Yan. Timosaponin AIII Suppresses RAP1 Signaling Pathway to Enhance the Inhibitory Effect of Paclitaxel on Nasopharyngeal Carcinoma. Computational and mathematical methods in medicine. vol 2022. 2022-05-19. PMID:35586672. |
cellular viability, apoptosis, apoptotic factors, and rap1 signaling regulators were detected in the pnc cells (cne-1 and hne-2) and the subcutaneous cne-1 transplanted nude mice treated with ptx or/and tsaiii. |
2022-05-19 |
2023-08-13 |
mouse |
| Wei Zhang, Jingyu Zhang, Zhi Hu, Wei Sun, Lv Xu, Hao Chu, Xiao Wang, Qiao F. LncRNA ARAP1-AS1 Promotes Bladder Cancer Development by Regulating the miR-3918/KIF20A Axis. Molecular biotechnology. 2022-05-13. PMID:35556220. |
the effects of arap1-as1, mir-3918, and kif20a on bladder cell activity, proliferation, apoptosis, and in vivo growth were examined using the cell counting kit-8, colony formation, caspase-3 activity, and xenograft tumor growth assays, respectively, in nude mice. |
2022-05-13 |
2023-08-13 |
mouse |
| Lu Zhang, Zhaomin Lin, Yuan Chen, Dongfang Gao, Peng Wang, Yuxing Lin, Yongmei Wang, Fang Wang, Ying Han, Huiqing Yua. Co-delivery of Docetaxel and Resveratrol by liposomes synergistically boosts antitumor efficiency against prostate cancer. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 2022-05-09. PMID:35533965. |
animal studies revealed that co-encapsulated doc/res in liposomes predominantly inhibited tumor growth in pc3 bearing balb/c nude mice, as evidenced by a change in cell proliferation and apoptosis parameters. |
2022-05-09 |
2023-08-13 |
mouse |