| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Wusong Xue, Siye Men, Renghai Li. Rotenone restrains the proliferation, motility and epithelial-mesenchymal transition of colon cancer cells and the tumourigenesis in nude mice via PI3K/AKT pathway. Clinical and experimental pharmacology & physiology. vol 47. issue 8. 2021-10-12. PMID:32282954. |
this study aims to clarify the effect of rotenone on the proliferation, apoptosis, invasion and migration of colon cancer cells and tumourigenesis in nude mice. |
2021-10-12 |
2023-08-13 |
mouse |
| Wusong Xue, Siye Men, Renghai Li. Rotenone restrains the proliferation, motility and epithelial-mesenchymal transition of colon cancer cells and the tumourigenesis in nude mice via PI3K/AKT pathway. Clinical and experimental pharmacology & physiology. vol 47. issue 8. 2021-10-12. PMID:32282954. |
therefore, rotenone inhibited the proliferation, invasion and migration, promoted the apoptosis of colon cancer cells through pi3k/akt pathway in vitro, and suppressed the tumourigenesis in nude mice in vivo. |
2021-10-12 |
2023-08-13 |
mouse |
| Jie Cui, Jiale Tian, Weiwei Wang, Tao He, Xin Li, Chenzheng Gu, Lixin Wang, Jian Wu, Anquan Shan. IGF2BP2 promotes the progression of colorectal cancer through a YAP-dependent mechanism. Cancer science. vol 112. issue 10. 2021-10-07. PMID:34309973. |
therefore, igf2bp2 promoted the expression of erbb2 to enhance the proliferation, invasion and migration of crc cells, to repress cell apoptosis, and to promote solid tumor formation in nude mice. |
2021-10-07 |
2023-08-13 |
mouse |
| Jingxian Fan, Fanlin Wan. MANCR drives esophageal carcinoma progression by targeting PDE4D. Journal of B.U.ON. : official journal of the Balkan Union of Oncology. vol 26. issue 4. 2021-09-26. PMID:34565013. |
to explore the role of lncrna mancr in regulating in vitro proliferation and apoptosis in esophageal carcinoma cells and in vivo growth of esophageal carcinoma in nude mice. |
2021-09-26 |
2023-08-13 |
mouse |
| Yu Huang, Fangyuan Lu. Elevated microRNA-130b-5p or silenced ELK1 inhibits self-renewal ability, proliferation, migration, and invasion abilities, and promotes apoptosis of cervical cancer stem cells. IUBMB life. vol 73. issue 1. 2021-09-21. PMID:33295145. |
elevated mir-130b-5p or silenced elk1 inhibited self-renewal ability and stemness, colony formation, proliferation, migration and invasion abilities, promoted apoptosis of cc stem cells, as well as decreased the weight and volume of tumor in nude mice. |
2021-09-21 |
2023-08-13 |
mouse |
| Xuehan Bi, Xiao Lv, Dajiang Liu, Hongtao Guo, Guang Yao, Lijuan Wang, Xiaolei Liang, Yongxiu Yan. METTL3 promotes the initiation and metastasis of ovarian cancer by inhibiting CCNG2 expression via promoting the maturation of pri-microRNA-1246. Cell death discovery. vol 7. issue 1. 2021-09-15. PMID:34497267. |
high expression of mettl3 downregulated ccng2, promoted the metabolism and growth of transplanted tumors in nude mice, and inhibited apoptosis. |
2021-09-15 |
2023-08-13 |
mouse |
| Jian Cao, Huan Wang, Guangquan Liu, Ranran Tang, Ye Ding, Pengfei Xu, Huayu Wang, Juan Miao, Xiaoyan Gu, Suping Ha. LBX2-AS1 promotes ovarian cancer progression by facilitating E2F2 gene expression via miR-455-5p and miR-491-5p sponging. Journal of cellular and molecular medicine. vol 25. issue 2. 2021-09-14. PMID:33342041. |
the overall cell growth, colony formation, migration, invasion, apoptosis and tumour formation on nude mice of ovarian cancer cells were evaluated before and after lentiviral-based lbx2-as1 knockdown. |
2021-09-14 |
2023-08-13 |
mouse |
| Dan Zhang, Xiaofang Xiao, Daqiang Song, Siwei Chen, Zhuo Zhang, Shousong Cao, Minghua Li. Atractylenolide III induces apoptosis by regulating the Bax/Bcl-2 signaling pathway in human colorectal cancer HCT-116 Cells in vitro and in vivo. Anti-cancer drugs. 2021-09-14. PMID:34261915. |
furthermore, atractylenolide iii also significantly inhibited the tumor growth of hct-116 tumor xenografts bearing in nude mice through inducing apoptosis by upregulation of the expressions of bax, cleaved caspase-3 and p53 but downregulation of the expressions of bcl-2 in hct-116 tumor tissues in vivo. |
2021-09-14 |
2023-08-13 |
mouse |
| Xin Peng, Guanming Chen, Baozhou Lv, Jiudi L. MicroRNA-148a/152 cluster restrains tumor stem cell phenotype of colon cancer via modulating CCT6A. Anti-cancer drugs. 2021-09-06. PMID:34486532. |
upregulated mir-148a/152 depressed cct6a expression and restrained invasion and migration ability, colony formation and proliferation, induced cell apoptosis, depressed oct4, nanog and sox2 mrna expression of colon cancer stem cells, and descended tumor weight and volume in nude mice. |
2021-09-06 |
2023-08-13 |
mouse |
| Xiaoliang Yang, Weidong Cao, Xiaofeng Wang, Xiang Zhang, Wei Zhang, Zenggang Li, Haian F. Down-regulation of 14-3-3zeta reduces proliferation and increases apoptosis in human glioblastoma. Cancer gene therapy. vol 27. issue 6. 2021-08-17. PMID:31068674. |
14-3-3zeta rnai reduced cell proliferation, induced apoptosis, decreased the invasive capability and colony-formation, and impaired the growth of glioblastoma xenografts in nude mice. |
2021-08-17 |
2023-08-13 |
mouse |
| Xiaodan Wu, Yihui Fan, Yupeng Liu, Biao Shen, Haimin Lu, Haitao M. Long Non-Coding RNA CCAT2 Promotes the Development of Esophageal Squamous Cell Carcinoma by Inhibiting miR-200b to Upregulate the IGF2BP2/TK1 Axis. Frontiers in oncology. vol 11. 2021-08-14. PMID:34386421. |
cell proliferation, apoptosis, migration, and invasion were examined by colony formation assay, flow cytometry, scratch assay, and transwell assay, respectively, while subcutaneous tumorigenesis in nude mice was adopted to examine the role of ccat2 in tumorigenesis of escc cells |
2021-08-14 |
2023-08-13 |
mouse |
| Ching-Yuan Wu, Yao-Hsu Yang, Yu-Shih Lin, Geng-He Chang, Ming-Shao Tsai, Cheng-Ming Hsu, Reming-Albert Yeh, Li-Hsin Shu, Yu-Ching Cheng, Hung-Te Li. Dihydroisotanshinone I induced ferroptosis and apoptosis of lung cancer cells. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 139. 2021-08-11. PMID:33862493. |
in conclusion, dt inhibited the growth of lung cancer cells through apoptosis and ferroptosis and inhibited metastasis of a549 cells in the nude mice model. |
2021-08-11 |
2023-08-13 |
mouse |
| Dongjie Du, Xiaoci Cao, Xinbo Duan, Xianbo Zhan. Blocking circ_0014130 suppressed drug resistance and malignant behaviors of docetaxel resistance-acquired NSCLC cells via regulating miR-545-3p-YAP1 axis. Cytotechnology. vol 73. issue 4. 2021-08-06. PMID:34349347. |
moreover, colony formation assay, flow cytometry, transwell assays, and xenograft tumor model revealed that silencing circ_0014130 facilitated apoptosis rate of dtx-resistant nsclc cells, suppressed the colony formation, migration and invasion, and retarded xenograft tumor growth in nude mice. |
2021-08-06 |
2023-08-13 |
mouse |
| Li-Jun Shen, Cheng-Lin Qi, Rui Yang, Mao-Ling Huang, You Zou, Yang Jiang, Jian-Fei Sheng, Yong-Gang Kong, Qing-Quan Hua, Shi-Ming Che. PLAC8 gene knockout increases the radio-sensitivity of xenograft tumors in nude mice with nasopharyngeal carcinoma by promoting apoptosis. American journal of translational research. vol 13. issue 6. 2021-07-27. PMID:34306339. |
plac8 gene knockout increases the radio-sensitivity of xenograft tumors in nude mice with nasopharyngeal carcinoma by promoting apoptosis. |
2021-07-27 |
2023-08-13 |
mouse |
| Cui-Cui Zhao, Jing Chen, Li-Ying Zhang, Hong Liu, Chuan-Gui Zhang, Yan Li. Lamin B2 promotes the progression of triple negative breast cancer via mediating cell proliferation and apoptosis. Bioscience reports. vol 41. issue 1. 2021-07-21. PMID:33416073. |
alterations in cell proliferation and apoptosis in vitro and the nude mouse tumorigenicity assay in vivo were subsequently analyzed. |
2021-07-21 |
2023-08-13 |
mouse |
| Jing Wang, Hongling Chen, Wanrong Li, Lingling Sha. Cordyceps acid alleviates lung cancer in nude mice. Journal of biochemical and molecular toxicology. vol 35. issue 3. 2021-07-13. PMID:33251677. |
the levels of nrf-2/ho-1/nlrp3/nf-κb pathway and apoptosis in tumor tissues of nude mice were detected by the western blot analysis and immunohistochemical methods. |
2021-07-13 |
2023-08-13 |
mouse |
| Minghuan Mao, Liang Yang, Jingyao Hu, Bing Liu, Chunlai Liu, Xiling Zhang, Yili Liu, Ping Wang, Hangyu L. OCT3/4 enhances tumor immune response by upregulating the TET1-dependent NRF2/MDM2 axis in bladder cancer. Genomics. vol 113. issue 4. 2021-07-07. PMID:33894310. |
initially, the expression of oct3/4, tet1, nrf2 and mdm2 was quantified in tumor tissues and cells, followed by gain- or loss-of-function studies to define their roles in cell migration, invasion and apoptosis and tumorigenicity in nude mice. |
2021-07-07 |
2023-08-13 |
mouse |
| Yi-Ping Huang, Yi-Shih Ma, Chao-Lin Kuo, Ching-Lung Liao, Po-Yuan Chen, Shu-Fen Peng, Fei-Ting Hsu, Kuang-Chi La. Demethoxycurcumin Suppresses Human Brain Glioblastoma Multiforme GBM 8401 Cell Xenograft Tumor in Nude Mice International journal of molecular sciences. vol 22. issue 11. 2021-06-21. PMID:34071132. |
demethoxycurcumin suppresses human brain glioblastoma multiforme gbm 8401 cell xenograft tumor in nude mice demethoxycurcumin (dmc), a derivate of curcumin, has been shown to induce apoptotic cell death in human glioblastoma multiforme gbm 8401 cells via cell cycle arrest and induction of cell apoptosis. |
2021-06-21 |
2023-08-13 |
mouse |
| Aya Naiki-Ito, Taku Naiki, Hiroyuki Kato, Keitaro Iida, Toshiki Etani, Yuko Nagayasu, Shugo Suzuki, Yoriko Yamashita, Shingo Inaguma, Masaya Onishi, Yasuhito Tanaka, Takahiro Yasui, Satoru Takahash. Recruitment of miR-8080 by luteolin inhibits androgen receptor splice variant 7 expression in castration-resistant prostate cancer. Carcinogenesis. vol 41. issue 8. 2021-06-09. PMID:31805186. |
dietary luteolin also suppressed tumor growth via an increase in apoptosis and inhibition of angiogenesis in pcai1 and 22rv1 xenografts implanted in castrated nude mice. |
2021-06-09 |
2023-08-13 |
mouse |
| Yue Wang, Yunyi Chen, He Zhang, Jiebiao Chen, Jinping Cao, Qingjun Chen, Xian Li, Chongde Su. Polymethoxyflavones from citrus inhibited gastric cancer cell proliferation through inducing apoptosis by upregulating RARβ, both in vitro and in vivo. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 146. 2021-06-07. PMID:33058988. |
moreover, a nude mice tumor xenograft model confirmed the tangeretin could exhibit in vivo anti-tumor effect through inducing apoptosis and upregulating rarβ protein. |
2021-06-07 |
2023-08-13 |
mouse |