| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lee-Han Kim, Sachita Khadka, Ji-Ae Shin, Ji-Youn Jung, Mi-Heon Ryu, Hyun-Ju Yu, Hae Nim Lee, Boonsil Jang, In-Hyoung Yang, Dong-Hoon Won, Hye-Jeong Kwon, Joseph H Jeong, Seong Doo Hong, Nam-Pyo Cho, Sung-Dae Ch. Nitidine chloride acts as an apoptosis inducer in human oral cancer cells and a nude mouse xenograft model via inhibition of STAT3. Oncotarget. vol 8. issue 53. 2019-11-20. PMID:29207645. |
nitidine chloride acts as an apoptosis inducer in human oral cancer cells and a nude mouse xenograft model via inhibition of stat3. |
2019-11-20 |
2023-08-13 |
mouse |
| Yuan Xiang, Xing-Hua Liao, Jia-Peng Li, Hui Li, Huan Qin, Ao Yao, Cheng-Xi Yu, Peng Hu, Wei Guo, Chao-Jiang Gu, Tong-Cun Zhan. Myocardin and Stat3 act synergistically to inhibit cardiomyocyte apoptosis. Oncotarget. vol 8. issue 59. 2019-11-20. PMID:29245928. |
myocardin and stat3 act synergistically to inhibit cardiomyocyte apoptosis. |
2019-11-20 |
2023-08-13 |
rat |
| Yuan Xiang, Xing-Hua Liao, Jia-Peng Li, Hui Li, Huan Qin, Ao Yao, Cheng-Xi Yu, Peng Hu, Wei Guo, Chao-Jiang Gu, Tong-Cun Zhan. Myocardin and Stat3 act synergistically to inhibit cardiomyocyte apoptosis. Oncotarget. vol 8. issue 59. 2019-11-20. PMID:29245928. |
signal transducer and activator of transcription 3 (stat3) and myocardin regulate cardiomyocyte differentiation, proliferation, and apoptosis. |
2019-11-20 |
2023-08-13 |
rat |
| Yuan Xiang, Xing-Hua Liao, Jia-Peng Li, Hui Li, Huan Qin, Ao Yao, Cheng-Xi Yu, Peng Hu, Wei Guo, Chao-Jiang Gu, Tong-Cun Zhan. Myocardin and Stat3 act synergistically to inhibit cardiomyocyte apoptosis. Oncotarget. vol 8. issue 59. 2019-11-20. PMID:29245928. |
we report a novel aspect of the cellular function of myocardin and stat3 in the regulation of cardiomyocyte apoptosis. |
2019-11-20 |
2023-08-13 |
rat |
| Yuan Xiang, Xing-Hua Liao, Jia-Peng Li, Hui Li, Huan Qin, Ao Yao, Cheng-Xi Yu, Peng Hu, Wei Guo, Chao-Jiang Gu, Tong-Cun Zhan. Myocardin and Stat3 act synergistically to inhibit cardiomyocyte apoptosis. Oncotarget. vol 8. issue 59. 2019-11-20. PMID:29245928. |
myocardin and stat3 synergistically inhibited staurosporine-induced cardiomyocyte apoptosis by up-regulating expression of anti-apoptotic bcl-2 and mcl-1 in neonatal rat cardiomyocytes. |
2019-11-20 |
2023-08-13 |
rat |
| Vinothkumar Rajamanickam, Heping Zhu, Chen Feng, Xi Chen, Hailun Zheng, Xiaohong Xu, Qianqian Zhang, Peng Zou, Guodong He, Xuanxuan Dai, Xi Yang, Yi Wang, Zhiguo Liu, Guang Liang, Guilong Gu. Novel allylated monocarbonyl analogs of curcumin induce mitotic arrest and apoptosis by reactive oxygen species-mediated endoplasmic reticulum stress and inhibition of STAT3. Oncotarget. vol 8. issue 60. 2019-11-20. PMID:29254150. |
novel allylated monocarbonyl analogs of curcumin induce mitotic arrest and apoptosis by reactive oxygen species-mediated endoplasmic reticulum stress and inhibition of stat3. |
2019-11-20 |
2023-08-13 |
mouse |
| Retraction: Gambogic Acid Inhibits STAT3 Phosphorylation through Activation of Protein Tyrosine Phosphatase SHP-1: Potential Role in Proliferation and Apoptosis. Cancer prevention research (Philadelphia, Pa.). vol 11. issue 9. 2019-11-20. PMID:30181122. |
retraction: gambogic acid inhibits stat3 phosphorylation through activation of protein tyrosine phosphatase shp-1: potential role in proliferation and apoptosis. |
2019-11-20 |
2023-08-13 |
Not clear |
| Seyung S Chung, Pranabananda Dutta, David Austin, Piwen Wang, Adam Awad, Jaydutt V Vadgam. Combination of resveratrol and 5-flurouracil enhanced anti-telomerase activity and apoptosis by inhibiting STAT3 and Akt signaling pathways in human colorectal cancer cells. Oncotarget. vol 9. issue 68. 2019-11-20. PMID:30250641. |
combination of resveratrol and 5-flurouracil enhanced anti-telomerase activity and apoptosis by inhibiting stat3 and akt signaling pathways in human colorectal cancer cells. |
2019-11-20 |
2023-08-13 |
human |
| Li Li, Yi Ji, Yan-Xia Ma, Liang-Qin Gao, Hong-Guang Zhou, Mian-Hua W. 6-Gingerol inhibits proliferation in gastric cancer via the STAT3 pathway in vitro. Cellular and molecular biology (Noisy-le-Grand, France). vol 65. issue 3. 2019-11-20. PMID:30942163. |
and a study on further pathways by western blot shows that gi brings about cell apoptosis by inhibiting the activation of stat3. |
2019-11-20 |
2023-08-13 |
human |
| L-L Huang, W Ra. SiRNA interfering STAT3 enhances DDP sensitivity in cervical cancer cells. European review for medical and pharmacological sciences. vol 22. issue 13. 2019-11-12. PMID:30024597. |
signal transducer and activator of transcription 3 (stat3) is an important regulatory protein in the janus kinase (jak)-signal transducer and activator of transcription (stat) pathway, which regulates cell proliferation, apoptosis, and other biological processes. |
2019-11-12 |
2023-08-13 |
Not clear |
| Y Zhang, L-M Zheng, C-X Wang, J-M Gu, S Xu. SENP3 protects H9C2 cells from apoptosis triggered by H/R via STAT3 pathway. European review for medical and pharmacological sciences. vol 22. issue 9. 2019-11-06. PMID:29771430. |
senp3 protects h9c2 cells from apoptosis triggered by h/r via stat3 pathway. |
2019-11-06 |
2023-08-13 |
Not clear |
| Y Zhang, L-M Zheng, C-X Wang, J-M Gu, S Xu. SENP3 protects H9C2 cells from apoptosis triggered by H/R via STAT3 pathway. European review for medical and pharmacological sciences. vol 22. issue 9. 2019-11-06. PMID:29771430. |
to investigate whether senp3 protects h9c2 cells from apoptosis triggered by h/r through the signal transducer and activator of transcription 3 (stat3) pathway. |
2019-11-06 |
2023-08-13 |
Not clear |
| Lingyuan Xu, Sensen Qiu, Lehe Yang, Haitang Xu, Xu Liu, Shiqian Fan, Ri Cui, Weitao Fu, Chengguang Zhao, Liqun Shen, Liangxing Wang, Xiaoying Huan. Aminocyanopyridines as anti-lung cancer agents by inhibiting the STAT3 pathway. Molecular carcinogenesis. vol 58. issue 8. 2019-11-05. PMID:31069881. |
they blocked the constitutive stat3 phosphorylation in a dose- and time-dependent manner and regulated the transcription of stat3 target genes encoding apoptosis factors. |
2019-11-05 |
2023-08-13 |
Not clear |
| Xusheng Xie, Xiaobin Zheng, Zhifen Han, Yufeng Chen, Zhaozhu Zheng, Bin Zheng, Xiaowen He, Yongfeng Wang, David L Kaplan, Yi Li, Gang Li, Xiaoqin Wang, Ping La. A Biodegradable Stent with Surface Functionalization of Combined-Therapy Drugs for Colorectal Cancer. Advanced healthcare materials. vol 7. issue 24. 2019-10-31. PMID:30468567. |
in vitro and in vivo studies on the nanofibrous memembrane-coating demonstrate improved antitumor effects for the cur/5-fu dual drug system which can be attributed to cell cycle arrest in the s phase in association with induced apoptosis in tumor cells by blocking signal transducer and activator of transcription3 (stat3) and nuclear factor kappa beta (nf-kb) signaling pathways, suggesting potential in the treatment of crc in the future. |
2019-10-31 |
2023-08-13 |
mouse |
| Xingxing Chen, Kun Han, Gang Lin, Changxin Liu, Shanghong Wang, Xiao Shi, Zhizhen Hu, Chuxin Wu, Xiaowen Xu, Chengyu H. Ctenopharyngodon Idella STAT3 alleviates autophagy by up-regulating BCL-2 expression. Fish & shellfish immunology. vol 91. 2019-10-29. PMID:31108175. |
as a downstream target gene of stat3, bcl-2 (b-cell lymphoma 2) not only participates in regulating apoptosis, but also responds to autophagy. |
2019-10-29 |
2023-08-13 |
human |
| Young-Il Hahn, Su-Jung Kim, Bu-Young Choi, Kyung-Cho Cho, Raju Bandu, Kwang Pyo Kim, Do-Hee Kim, Wonki Kim, Joon Sung Park, Byung Woo Han, Jeewoo Lee, Hye-Kyung Na, Young-Nam Cha, Young-Joon Sur. Curcumin interacts directly with the Cysteine 259 residue of STAT3 and induces apoptosis in H-Ras transformed human mammary epithelial cells. Scientific reports. vol 8. issue 1. 2019-10-28. PMID:29686295. |
curcumin interacts directly with the cysteine 259 residue of stat3 and induces apoptosis in h-ras transformed human mammary epithelial cells. |
2019-10-28 |
2023-08-13 |
human |
| Young-Il Hahn, Su-Jung Kim, Bu-Young Choi, Kyung-Cho Cho, Raju Bandu, Kwang Pyo Kim, Do-Hee Kim, Wonki Kim, Joon Sung Park, Byung Woo Han, Jeewoo Lee, Hye-Kyung Na, Young-Nam Cha, Young-Joon Sur. Curcumin interacts directly with the Cysteine 259 residue of STAT3 and induces apoptosis in H-Ras transformed human mammary epithelial cells. Scientific reports. vol 8. issue 1. 2019-10-28. PMID:29686295. |
site-directed mutation of this cysteine residue abolished curcumin-induced inactivation of stat3 and apoptosis in h-ras mcf10a cells. |
2019-10-28 |
2023-08-13 |
human |
| Young-Il Hahn, Su-Jung Kim, Bu-Young Choi, Kyung-Cho Cho, Raju Bandu, Kwang Pyo Kim, Do-Hee Kim, Wonki Kim, Joon Sung Park, Byung Woo Han, Jeewoo Lee, Hye-Kyung Na, Young-Nam Cha, Young-Joon Sur. Curcumin interacts directly with the Cysteine 259 residue of STAT3 and induces apoptosis in H-Ras transformed human mammary epithelial cells. Scientific reports. vol 8. issue 1. 2019-10-28. PMID:29686295. |
tetrahydrocurcumin that lacks such electrophilic moiety failed to interact with stat3 and to induce apoptosis in the same cell line. |
2019-10-28 |
2023-08-13 |
human |
| Elli Narvi, Katri Vaparanta, Anna Karrila, Deepankar Chakroborty, Sakari Knuutila, Arto Pulliainen, Maria Sundvall, Klaus Eleniu. Different responses of colorectal cancer cells to alternative sequences of cetuximab and oxaliplatin. Scientific reports. vol 8. issue 1. 2019-10-28. PMID:30410004. |
in contrast, oxaliplatin-enhanced responsiveness to subsequent treatment with cetuximab was associated with increased apoptosis, inhibition of stat3 activity and increased egfr down-regulation. |
2019-10-28 |
2023-08-13 |
Not clear |
| Zhang-Ming Chen, Lei Huang, Miao-Miao Li, Lei Meng, Song-Cheng Ying, A-Man X. Inhibitory effects of isocryptotanshinone on gastric cancer. Scientific reports. vol 8. issue 1. 2019-10-09. PMID:29915371. |
together, these data indicate that icts inhibits gc proliferation by inducing g1/g0 cell cycle arrest and apoptosis via inhibiting the stat3 signaling pathway. |
2019-10-09 |
2023-08-13 |
mouse |