| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Deniz Bagdas, Yasmin Alkhlaif, Asti Jackson, F Ivy Carroll, Joseph W Ditre, M Imad Dama. New insights on the effects of varenicline on nicotine reward, withdrawal and hyperalgesia in mice. Neuropharmacology. vol 138. 2019-02-13. PMID:29860196. |
moreover, the effects of varenicline on nicotine withdrawal-induced hyperalgesia and aversion are unknown. |
2019-02-13 |
2023-08-13 |
mouse |
| Deniz Bagdas, Yasmin Alkhlaif, Asti Jackson, F Ivy Carroll, Joseph W Ditre, M Imad Dama. New insights on the effects of varenicline on nicotine reward, withdrawal and hyperalgesia in mice. Neuropharmacology. vol 138. 2019-02-13. PMID:29860196. |
furthermore, varenicline (0.1 and 0.5 mg/kg) reversed nicotine withdrawal signs such as hyperalgesia and somatic signs and withdrawal-induced aversion in a dose-related manner. |
2019-02-13 |
2023-08-13 |
mouse |
| Zhuo Wang, Harriet H Chang, Yunliang Gao, Rong Zhang, Yumei Guo, Daniel P Holschneider, Larissa V Rodrigue. Effects of water avoidance stress on peripheral and central responses during bladder filling in the rat: A multidisciplinary approach to the study of urologic chronic pelvic pain syndrome (MAPP) research network study. PloS one. vol 12. issue 9. 2017-10-18. PMID:28886046. |
chronic water avoidance stress (was) in rodents is a model with high construct and face validity to bladder hypersensitive syndromes, such as interstitial cystitis/bladder pain syndrome (ic/bps), characterized by urinary frequency and bladder hyperalgesia and heightened stress responsiveness. |
2017-10-18 |
2023-08-13 |
rat |
| A Lenore Ackerman, Forrest C Jellison, Una J Lee, Sylvie Bradesi, Larissa V Rodrígue. The Glt1 glutamate receptor mediates the establishment and perpetuation of chronic visceral pain in an animal model of stress-induced bladder hyperalgesia. American journal of physiology. Renal physiology. vol 310. issue 7. 2017-07-03. PMID:26697981. |
in a model of stress-induced bladder hyperalgesia with high construct validity to human ic/bps, female wistar-kyoto (wky) rats were subjected to 10-day water avoidance stress (was). |
2017-07-03 |
2023-08-13 |
human |
| B KuKanic. Pharmacokinetics and pharmacodynamics of oral acetaminophen in combination with codeine in healthy Greyhound dogs. Journal of veterinary pharmacology and therapeutics. vol 39. issue 5. 2017-06-23. PMID:26896302. |
the decrease in vf thresholds at 12 h could be due to aversion, hyperalgesia, or random variability. |
2017-06-23 |
2023-08-13 |
dog |
| Shi-Hao Gao, Hui-Zhong Wen, Lin-Lin Shen, Yan-Dong Zhao, Huai-Zhen Rua. Activation of mGluR1 contributes to neuronal hyperexcitability in the rat anterior cingulate cortex via inhibition of HCN channels. Neuropharmacology. vol 105. 2017-06-22. PMID:26829470. |
for behavioral tests, intra-acc microinjection of mglur1-shrna suppressed the cci-induced behavioral hypersensitivity, particularly thermal hyperalgesia, but not aversive behavior, and this effect was attenuated by the pre-blockade of hcn channels. |
2017-06-22 |
2023-08-13 |
rat |
| Ryan B Griggs, Renee R Donahue, Braxton G Adkins, Katie L Anderson, Olivier Thibault, Bradley K Taylo. Pioglitazone Inhibits the Development of Hyperalgesia and Sensitization of Spinal Nociresponsive Neurons in Type 2 Diabetes. The journal of pain. vol 17. issue 3. 2016-12-13. PMID:26687453. |
compared with zucker lean (zl(fa/+)) controls, zdf rats developed: (1) increased blood glucose, hemoglobin a1c, methylglyoxal, and insulin levels; (2) mechanical and thermal hyperalgesia in the hind paw; (3) increased avoidance of noxious mechanical probes in a mechanical conflict avoidance behavioral assay, to our knowledge, the first report of a measure of affective-motivational pain-like behavior in zdf rats; and (4) exaggerated lumbar dorsal horn immunohistochemical expression of pressure-evoked phosphorylated extracellular signal-regulated kinase. |
2016-12-13 |
2023-08-13 |
rat |
| Gray Moonen, Kajana Satkunendrarajah, Jared T Wilcox, Anna Badner, Andrea Mothe, Warren Foltz, Michael G Fehlings, Charles H Tato. A New Acute Impact-Compression Lumbar Spinal Cord Injury Model in the Rodent. Journal of neurotrauma. vol 33. issue 3. 2016-10-31. PMID:26414192. |
evaluation of sensory outcomes revealed highly pathological alterations including mechanical allodynia and thermal hyperalgesia indicated by increasing avoidance responses and decreasing latency in the tail-flick test. |
2016-10-31 |
2023-08-13 |
rat |
| Yan Liu, Liu Yang, Jin Yu, Yu-Qiu Zhan. Persistent, comorbid pain and anxiety can be uncoupled in a mouse model. Physiology & behavior. vol 151. 2016-06-28. PMID:26166157. |
cfa-inflammatory mice showed robust mechanical allodynia and thermal hyperalgesia in both strains, but did not develop obvious social avoidance and anxiety-like behaviors 10 days after cfa-inflammation. |
2016-06-28 |
2023-08-13 |
mouse |
| Tao Wang, Olivia Hurwitz, Steven G Shimada, Lintao Qu, Kai Fu, Pu Zhang, Chao Ma, Robert H LaMott. Chronic Compression of the Dorsal Root Ganglion Enhances Mechanically Evoked Pain Behavior and the Activity of Cutaneous Nociceptors in Mice. PloS one. vol 10. issue 9. 2016-05-23. PMID:26356638. |
we conclude that ccd produced both a behavioral hyperalgesia and an enhanced response of cutaneous c-nociceptors to aversive punctate mechanical stimuli. |
2016-05-23 |
2023-08-13 |
mouse |
| Andrew Curtright, Micaela Rosser, Shamii Goh, Bailey Keown, Erinn Wagner, Jasmine Sharifi, David W Raible, Ajay Dhak. Modeling nociception in zebrafish: a way forward for unbiased analgesic discovery. PloS one. vol 10. issue 1. 2015-12-14. PMID:25587718. |
modeling thermal hyperalgesia, the addition of the noxious inflammatory compound and trpa1 agonist allyl isothiocyanate sensitized heat aversion and reversed cool aversion leading larvae to avoid rearing temperature in favor of otherwise acutely aversive cooler temperatures. |
2015-12-14 |
2023-08-13 |
zebrafish |
| D Pratt, P N Fuchs, K A Sluk. Assessment of avoidance behaviors in mouse models of muscle pain. Neuroscience. vol 248. 2015-10-20. PMID:23747349. |
in the carrageenan model of inflammation mice developed escape-avoidance behaviors to mechanical stimuli, learned avoidance to mechanical stimulation and avoidance of physical activity - these models are associated with unilateral hyperalgesia. |
2015-10-20 |
2023-08-12 |
mouse |
| D Pratt, P N Fuchs, K A Sluk. Assessment of avoidance behaviors in mouse models of muscle pain. Neuroscience. vol 248. 2015-10-20. PMID:23747349. |
in the exercise-enhanced pain model, there were no changes in escape-avoidance, learned avoidance of noxious or physical activity in conclusion, we developed several testing protocols that assess supraspinal processing of pain behaviors in models of muscle pain and that are most sensitive in animals with unilateral hyperalgesia. |
2015-10-20 |
2023-08-12 |
mouse |
| Una J Lee, A Lenore Ackerman, Ais Wu, Rong Zhang, Joanne Leung, Sylvie Bradesi, Emeran A Mayer, Larissa V Rodrígue. Chronic psychological stress in high-anxiety rats induces sustained bladder hyperalgesia. Physiology & behavior. vol 139. 2015-08-31. PMID:25449389. |
to evaluate whether anxiety-prone rats exposed to chronic water avoidance stress (was) develop visceral bladder hyperalgesia in addition to increased voiding frequency and anxiety-related behaviors. |
2015-08-31 |
2023-08-13 |
rat |
| Amynah A Pradhan, Monique L Smith, Jekaterina Zyuzin, Andrew Charle. δ-Opioid receptor agonists inhibit migraine-related hyperalgesia, aversive state and cortical spreading depression in mice. British journal of pharmacology. vol 171. issue 9. 2014-12-08. PMID:24467301. |
δ-opioid receptor agonists inhibit migraine-related hyperalgesia, aversive state and cortical spreading depression in mice. |
2014-12-08 |
2023-08-12 |
mouse |
| Kazuko Noda, Hisanao Akita, Masanori Ogata, Makoto Saj. Paclitaxel-induced hyperalgesia modulates negative affective component of pain and NR1 receptor expression in the frontal cortex in rats. Neuroscience research. vol 80. 2014-12-04. PMID:24440197. |
the effect of paclitaxel-induced hyperalgesia on the affective component of pain was assessed using pain-induced place aversion. |
2014-12-04 |
2023-08-12 |
rat |
| Pierre Veinante, Ipek Yalcin, Michel Barro. The amygdala between sensation and affect: a role in pain. Journal of molecular psychiatry. vol 1. issue 1. 2014-11-21. PMID:25408902. |
on the contrary, during persistent pain states (inflammatory, visceral, neuropathic), a long-lasting functional plasticity of cea activity contributes to an enhancement of the pain experience, including hyperalgesia, aversive behavioral reactions and affective anxiety-like states. |
2014-11-21 |
2023-08-13 |
human |
| Gonzalo Miguez, Mario A Laborda, Ralph R Mille. Classical conditioning and pain: conditioned analgesia and hyperalgesia. Acta psychologica. vol 145. 2014-05-16. PMID:24269884. |
specifically, the literature suggests that cues associated with stress can produce conditioned analgesia or conditioned hyperalgesia, depending on the properties of the conditioned stimulus (e.g., contextual cues and audiovisual cues vs. gustatory and olfactory cues, respectively) and the proprieties of the unconditioned stimulus (e.g., appetitive, aversive, or analgesic, respectively). |
2014-05-16 |
2023-08-12 |
Not clear |
| Zhuo Wang, Marco A Ocampo, Raina D Pang, Mihail Bota, Sylvie Bradesi, Emeran A Mayer, Daniel P Holschneide. Alterations in prefrontal-limbic functional activation and connectivity in chronic stress-induced visceral hyperalgesia. PloS one. vol 8. issue 3. 2013-09-27. PMID:23527114. |
repeated water avoidance stress (was) induces sustained visceral hyperalgesia (vh) in rats measured as enhanced visceromotor response to colorectal distension (crd). |
2013-09-27 |
2023-08-12 |
human |
| Yves Boucher, Mirela Iodi Carstens, Carolyn M Sawyer, Karen L Zanotto, Austin W Merrill, E Carsten. Capsaicin avoidance as a measure of chemical hyperalgesia in orofacial nerve injury models. Neuroscience letters. vol 543. 2013-09-06. PMID:23562513. |
capsaicin avoidance as a measure of chemical hyperalgesia in orofacial nerve injury models. |
2013-09-06 |
2023-08-12 |
rat |