| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yves Boucher, Mirela Iodi Carstens, Carolyn M Sawyer, Karen L Zanotto, Austin W Merrill, E Carsten. Capsaicin avoidance as a measure of chemical hyperalgesia in orofacial nerve injury models. Neuroscience letters. vol 543. 2013-09-06. PMID:23562513. |
mental nerve cci resulted in an enhancement of capsaicin avoidance in a two-bottle preference paradigm, while neither mental nerve injury produced thermal hyperalgesia or mechanical allodynia. |
2013-09-06 |
2023-08-12 |
rat |
| Keisuke Yamamoto, Tetsuya Takao, Jiro Nakayama, Hiroshi Kiuchi, Hidenobu Okuda, Shinichiro Fukuhara, Iwao Yoshioka, Yasuhiro Matsuoka, Yasushi Miyagawa, Akira Tsujimura, Norio Nonomur. Water avoidance stress induces frequency through cyclooxygenase-2 expression: a bladder rat model. International journal of urology : official journal of the Japanese Urological Association. vol 19. issue 2. 2012-06-05. PMID:22142485. |
water avoidance stress is a potent psychological stressor and it is associated with visceral hyperalgesia, which shows degeneration of the urothelial layer mimicking interstitial cystitis. |
2012-06-05 |
2023-08-12 |
rat |
| Daniel T Babcock, Shanping Shi, Juyeon Jo, Michael Shaw, Howard B Gutstein, Michael J Galk. Hedgehog signaling regulates nociceptive sensitization. Current biology : CB. vol 21. issue 18. 2012-02-07. PMID:21906949. |
this sensitization manifests as allodynia (aversive withdrawal to previously nonnoxious stimuli) and/or hyperalgesia (exaggerated responsiveness to noxious stimuli). |
2012-02-07 |
2023-08-12 |
Not clear |
| Joris Vriens, Grzegorz Owsianik, Thomas Hofmann, Stephan E Philipp, Julia Stab, Xiaodi Chen, Melissa Benoit, Fenqin Xue, Annelies Janssens, Sara Kerselaers, Johannes Oberwinkler, Rudi Vennekens, Thomas Gudermann, Bernd Nilius, Thomas Voet. TRPM3 is a nociceptor channel involved in the detection of noxious heat. Neuron. vol 70. issue 3. 2011-07-11. PMID:21555074. |
trpm3-deficient mice exhibited clear deficits in their avoidance responses to noxious heat and in the development of inflammatory heat hyperalgesia. |
2011-07-11 |
2023-08-12 |
mouse |
| Yan-Bo Yu, Jing Yang, Xiu-Li Zuo, Li-Jun Gao, Peng Wang, Yan-Qing L. Transient receptor potential vanilloid-1 (TRPV1) and ankyrin-1 (TRPA1) participate in visceral hyperalgesia in chronic water avoidance stress rat model. Neurochemical research. vol 35. issue 5. 2010-07-08. PMID:20182791. |
transient receptor potential vanilloid-1 (trpv1) and ankyrin-1 (trpa1) participate in visceral hyperalgesia in chronic water avoidance stress rat model. |
2010-07-08 |
2023-08-12 |
rat |
| Merab G Tsagareli, Nana Tsiklauri, Karen L Zanotto, Mirela Iodi Carstens, Amanda H Klein, Carolyn M Sawyer, Gulnazi Gurtskaia, Elene Abzianidze, E Carsten. Behavioral evidence of thermal hyperalgesia and mechanical allodynia induced by intradermal cinnamaldehyde in rats. Neuroscience letters. vol 473. issue 3. 2010-05-17. PMID:20219630. |
bilateral intraplantar injections of ca resulted in a significant cold hyperalgesia (cold plate test) and a weak enhancement of innocuous cold avoidance (thermal preference test). |
2010-05-17 |
2023-08-12 |
human |
| K J Jackson, J M McIntosh, D H Brunzell, S S Sanjakdar, M I Dama. The role of alpha6-containing nicotinic acetylcholine receptors in nicotine reward and withdrawal. The Journal of pharmacology and experimental therapeutics. vol 331. issue 2. 2009-11-30. PMID:19644040. |
we further measured physical (somatic signs and hyperalgesia) and affective [anxiety-related behavior and conditioned place aversion (cpa)] nicotine withdrawal behaviors after extended nicotine exposure. |
2009-11-30 |
2023-08-12 |
Not clear |
| S Hong, J Fan, E S Kemmerer, S Evans, Y Li, J W Wile. Reciprocal changes in vanilloid (TRPV1) and endocannabinoid (CB1) receptors contribute to visceral hyperalgesia in the water avoidance stressed rat. Gut. vol 58. issue 2. 2009-02-10. PMID:18936104. |
reciprocal changes in vanilloid (trpv1) and endocannabinoid (cb1) receptors contribute to visceral hyperalgesia in the water avoidance stressed rat. |
2009-02-10 |
2023-08-12 |
rat |
| K J Jackson, B R Martin, J P Changeux, M I Dama. Differential role of nicotinic acetylcholine receptor subunits in physical and affective nicotine withdrawal signs. The Journal of pharmacology and experimental therapeutics. vol 325. issue 1. 2008-04-22. PMID:18184829. |
our results show a loss of anxiety-related behavior and a loss of aversion in the cpa model in beta2 ko mice, whereas alpha7 and alpha5 ko mice displayed a loss of nicotine withdrawal-induced hyperalgesia and a reduction in somatic signs, respectively. |
2008-04-22 |
2023-08-12 |
mouse |
| Andreas Themistocleous, Peter Kamerman, Duncan Mitchel. Pre-emptive ring-block with bupivacaine prevents the development of thermal hyperalgesia, but not sustained mechanical hyperalgesia, in rat tails exposed to ultraviolet A light. The journal of pain. vol 8. issue 3. 2007-05-22. PMID:17140854. |
primary mechanical hyperalgesia was assessed daily from day 1 to day 14 after uva-light exposure by measuring aversive behavior responses to a punctate pressure applied to the tail with a von frey anesthesiometer. |
2007-05-22 |
2023-08-12 |
rat |
| Sylvie Bradesi, Ines Schwetz, Helena S Ennes, Christophe M R Lamy, Gordon Ohning, Michael Fanselow, Charalabos Pothoulakis, James A McRoberts, Emeran A Maye. Repeated exposure to water avoidance stress in rats: a new model for sustained visceral hyperalgesia. American journal of physiology. Gastrointestinal and liver physiology. vol 289. issue 1. 2005-08-02. PMID:15746211. |
repeated exposure to water avoidance stress in rats: a new model for sustained visceral hyperalgesia. |
2005-08-02 |
2023-08-12 |
rat |
| Adam R Ferguson, Brianne C Patton, Anne C Bopp, Mary W Meagher, James W Gra. Brief exposure to a mild stressor enhances morphine-conditioned place preference in male rats. Psychopharmacology. vol 175. issue 1. 2005-02-08. PMID:15060758. |
this hyperalgesia reflects an unconditioned response that transfers across contexts and is associated with enhanced pavlovian fear conditioning to aversive unconditioned stimuli (us). |
2005-02-08 |
2023-08-12 |
rat |
| b' Mulugeta Million, Dimitri E Grigoriadis, Sue Sullivan, Paul D Crowe, James A McRoberts, Huping Zhou, Paul R Saunders, Celine Maillot, Emeran A Mayer, Yvette Tach\\xc3\\xa. A novel water-soluble selective CRF1 receptor antagonist, NBI 35965, blunts stress-induced visceral hyperalgesia and colonic motor function in rats. Brain research. vol 985. issue 1. 2003-11-28. PMID:12957366.' |
the data show that nbi 35965 is a novel water-soluble selective crf1 antagonist with bioavailability to the brain upon peripheral administration and that crf1 receptor signaling pathways are involved in water avoidance stress-induced hyperalgesia to colorectal distention and stimulation of colonic transit. |
2003-11-28 |
2023-08-12 |
rat |
| Paul Coulthard, Shabana U Simjee, Barbara J Pleuvr. Gait analysis as a correlate of pain induced by carrageenan intraplantar injection. Journal of neuroscience methods. vol 128. issue 1-2. 2003-11-05. PMID:12948552. |
it is hypothesised that the temporal and spatial changes in gait observed in this model of acute inflammatory hyperalgesia may have been due to avoidance of the normally non-noxious mechanical stimulation induced by walking. |
2003-11-05 |
2023-08-12 |
Not clear |
| N Hirakawa, S A Tershner, H L Fields, B H Mannin. Bi-directional changes in affective state elicited by manipulation of medullary pain-modulatory circuitry. Neuroscience. vol 100. issue 4. 2001-01-18. PMID:11036220. |
hyperalgesia on the tail flick assay) and a negative affective state (as inferred from the production of conditioned place avoidance) in the conscious, freely moving rat. |
2001-01-18 |
2023-08-12 |
rat |
| T E King, E D Crown, A N Sieve, R L Joynes, J W Grau, M W Meaghe. Shock-induced hyperalgesia: evidence forebrain systems play an essential role. Behavioural brain research. vol 100. issue 1-2. 1999-07-28. PMID:10212051. |
prior work indicates that this hyperalgesia represents an unconditioned response and that it enhances the acquisition of both conditioned freezing and an avoidance response to thermal pain. |
1999-07-28 |
2023-08-12 |
rat |
| K Okano, Y Kuraishi, M Sato. Involvement of spinal substance P and excitatory amino acids in inflammatory hyperalgesia in rats. Japanese journal of pharmacology. vol 76. issue 1. 1998-05-12. PMID:9517400. |
furthermore, to estimate whether inflammatory hyperalgesia is accompanied with an alteration of the responsiveness to substance p and excitatory amino acids, we examined the effects of injections of complete freund's adjuvant (intradermal) and carrageenin (subcutaneous) on the aversive responses to intrathecal substance p and excitatory amino acid agonists. |
1998-05-12 |
2023-08-12 |
rat |
| K Okano, Y Kuraishi, M Sato. Involvement of spinal substance P and excitatory amino acids in inflammatory hyperalgesia in rats. Japanese journal of pharmacology. vol 76. issue 1. 1998-05-12. PMID:9517400. |
both injections significantly potentiated the aversive behaviors elicited by intrathecal injections of excitatory amino acid agonists, nmda (1 nmol/rat), a-amino-3-hydroxy-5-methylisoxazole-4-propionate (ampa, 1 nmol/rat) and kainate (1 nmol/rat), but not those by substance p. the present results suggest that the enhancement of synaptic transmission mediated by substance p and excitatory amino acids in the spinal dorsal horn is at least partly involved in the production of inflammatory hyperalgesia, and that such a hyperalgesia is accompanied with the enhanced responsiveness to excitatory amino acids through nmda and non-nmda receptors, but not with changes in responsiveness to substance p. |
1998-05-12 |
2023-08-12 |
rat |
| C Kawanishi, M Fukuda, R Tamura, H Nishijo, T On. Effects of repeated cold stress on feeding, avoidance behavior, and pain-related nerve fiber activity. Physiology & behavior. vol 62. issue 4. 1997-10-28. PMID:9284507. |
this suggests that the hyperreactivity in footshock avoidance and the hyperalgesia in pain response induced by sart stress are based on excessive emotionality. |
1997-10-28 |
2023-08-12 |
rat |
| K A Sluka, M A Milton, W D Willis, K N Westlun. Differential roles of neurokinin 1 and neurokinin 2 receptors in the development and maintenance of heat hyperalgesia induced by acute inflammation. British journal of pharmacology. vol 120. issue 7. 1997-06-24. PMID:9105701. |
pretreatment systemically with the nk1 receptor antagonist (30 mg kg-1) had no effect on the heat hyperalgesia or pain-related behaviour ratings where 0 is none and 5 is non weight bearing and complete avoidance of limb contact. |
1997-06-24 |
2023-08-12 |
rat |