| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Eric P Wicrtelak, Katherine P Smith, Linda Furness, Kelli Mooney-Heiberger, Tiffany Mayr, Steven F Maier, Linda R Watkin. Acute and conditioned hyperalgesic responses to illness. Pain. vol 56. issue 2. 1994-07-19. PMID:8008412. |
in addition, a conditioned taste aversion paradigm was used to examine the possibility that illness-induced hyperalgesia could be conditioned to a novel taste (saccharine). |
1994-07-19 |
2023-08-12 |
rat |
| S R Hamann, W R Marti. Hyperalgesic and analgesic actions of morphine, U50-488, naltrexone, and (-)-lobeline in the rat brainstem. Pharmacology, biochemistry, and behavior. vol 47. issue 1. 1994-03-25. PMID:8115422. |
morphine, u50-488, and (-)-lobeline produced dose-related shortening of a low-intensity thermally evoked tail avoidance response (litetar) (e.g., hyperalgesia) when microinjected into the dorsal posterior mesencephalic tegmentum (dpmt) of conscious rats. |
1994-03-25 |
2023-08-12 |
rat |
| S R Hamann, W R Marti. Opioid and nicotinic analgesic and hyperalgesic loci in the rat brain stem. The Journal of pharmacology and experimental therapeutics. vol 261. issue 2. 1992-06-05. PMID:1315863. |
additional experiments evaluated the validity and reproducibility of the low-intensity thermally evoked tail avoidance response and a low intensity hot plate response in detecting hyperalgesia. |
1992-06-05 |
2023-08-11 |
rat |
| P A Illich, J A Salinas, J W Gra. Conditioned changes in pain reactivity: II. In search of the elusive phenomenon of conditioned hyperalgesia. Behavioral neuroscience. vol 105. issue 3. 1991-09-09. PMID:1863368. |
previous research suggests that a stimulus that has been paired with an aversive event can elicit either an increase (hyperalgesia) or decrease (hypoalgesia) in pain reactivity in rats. |
1991-09-09 |
2023-08-11 |
rat |
| L D Matzel, R R Mille. Development of shock-induced analgesia: a search for hyperalgesia. Behavioral neuroscience. vol 103. issue 4. 1989-09-27. PMID:2765188. |
with the use of parameters intended to maximize the potential to observe hyperalgesia, the possibility was examined that hyperalgesia might be the immediate response to aversive stimulation, whereas analgesia is delayed (matzel & miller, 1987). |
1989-09-27 |
2023-08-11 |
rat |
| R Oku, M Satoh, N Fujii, A Otaka, H Yajima, H Takag. Calcitonin gene-related peptide promotes mechanical nociception by potentiating release of substance P from the spinal dorsal horn in rats. Brain research. vol 403. issue 2. 1987-05-20. PMID:2435372. |
on the other hand, when cgrp (5 nmol/rat) was intrathecally injected, the peptide produced a significant hyperalgesia to mechanical noxious stimuli (pinching the hind paw), but aversive responses and potentiation of substance p-induced aversive responses were never observed. |
1987-05-20 |
2023-08-11 |
rat |
| C Van Petten, W J Roberts, D L Rhode. Behavioral test of tolerance for aversive mechanical stimuli in sympathectomized cats. Pain. vol 15. issue 2. 1983-06-10. PMID:6844026. |
the new methodology appears to provide relatively stable, quantitative measures of tolerance for aversive stimulation, and the cat shows promise as an animal model for post-sympathectomy hyperalgesia. |
1983-06-10 |
2023-08-12 |
cat |