| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Anna Tchenio, Kristina Valentinova, Manuel Mamel. Can the Lateral Habenula Crack the Serotonin Code? Frontiers in synaptic neuroscience. vol 8. 2020-10-01. PMID:27822183. |
the lateral habenula (lhb) and the serotonergic system both contribute to motivational states by encoding rewarding and aversive signals. |
2020-10-01 |
2023-08-13 |
Not clear |
| Alvaro Nuno-Perez, Anna Tchenio, Manuel Mameli, Salvatore Lecc. Lateral Habenula Gone Awry in Depression: Bridging Cellular Adaptations With Therapeutics. Frontiers in neuroscience. vol 12. 2020-10-01. PMID:30083090. |
evidence from humans and animal models indicate that the lateral habenula (lhb), an epithalamic center devoted to processing aversive stimuli, is aberrantly affected during depression. |
2020-10-01 |
2023-08-13 |
Not clear |
| Rao Fu, Qinghua Mei, Wanhong Zuo, Jing Li, Danielle Gregor, Alex Bekker, Jianghong Y. Low-dose ethanol excites lateral habenula neurons projecting to VTA, RMTg, and raphe. International journal of physiology, pathophysiology and pharmacology. vol 9. issue 6. 2020-09-30. PMID:29348799. |
the lateral habenula (lhb) is a key brain structure responding to various aversive stimuli, including those related to alcohol. |
2020-09-30 |
2023-08-13 |
rat |
| Nicolas Iván Bertone-Cueto, Julia Makarova, Alejo Mosqueira, Demian García-Violini, Ricardo Sánchez-Peña, Oscar Herreras, Mariano Belluscio, Joaquin Piri. Volume-Conducted Origin of the Field Potential at the Lateral Habenula. Frontiers in systems neuroscience. vol 13. 2020-09-29. PMID:31998083. |
the lateral habenula (lhb) is a brain structure involved in the encoding of aversive motivational values. |
2020-09-29 |
2023-08-13 |
rat |
| Mauro Congiu, Massimo Trusel, Marco Pistis, Manuel Mameli, Salvatore Lecc. Opposite responses to aversive stimuli in lateral habenula neurons. The European journal of neuroscience. vol 50. issue 6. 2020-08-12. PMID:30860301. |
opposite responses to aversive stimuli in lateral habenula neurons. |
2020-08-12 |
2023-08-13 |
mouse |
| Mauro Congiu, Massimo Trusel, Marco Pistis, Manuel Mameli, Salvatore Lecc. Opposite responses to aversive stimuli in lateral habenula neurons. The European journal of neuroscience. vol 50. issue 6. 2020-08-12. PMID:30860301. |
among them, the epithalamic lateral habenula (lhb) plays a pivotal role in processing salient stimuli of aversive valence. |
2020-08-12 |
2023-08-13 |
mouse |
| Wenting Li, Wanhong Zuo, Wei Wu, Qi Kang Zuo, Rao Fu, Liangzhi Wu, Haifeng Zhang, Michael Ndukwe, Jiang-Hong Y. Activation of glycine receptors in the lateral habenula rescues anxiety- and depression-like behaviors associated with alcohol withdrawal and reduces alcohol intake in rats. Neuropharmacology. vol 157. 2020-07-21. PMID:31254534. |
the lateral habenula (lhb) is activated by a range of aversive states including those related to alcohol withdrawal and has glycine receptors (glyrs), a sensitive target of alcohol. |
2020-07-21 |
2023-08-13 |
rat |
| Peter J Vento, Thomas C Jho. Bidirectional Valence Encoding in the Ventral Pallidum. Neuron. vol 105. issue 5. 2020-06-18. PMID:32135088. |
(2020) dissect the function of the enigmatic ventral pallidum and elegantly demonstrate positive and negative valence encoding in its gaba and glutamate neurons that influence both approach and avoidance behavior via the lateral habenula. |
2020-06-18 |
2023-08-13 |
Not clear |
| Iakovos Lazaridis, Ourania Tzortzi, Moritz Weglage, Antje Märtin, Yang Xuan, Marc Parent, Yvonne Johansson, Janos Fuzik, Daniel Fürth, Lief E Fenno, Charu Ramakrishnan, Gilad Silberberg, Karl Deisseroth, Marie Carlén, Konstantinos Meleti. A hypothalamus-habenula circuit controls aversion. Molecular psychiatry. vol 24. issue 9. 2020-04-27. PMID:30755721. |
the lateral habenula (lhb) has been linked to aversion and mood regulation through modulation of the dopamine and serotonin systems. |
2020-04-27 |
2023-08-13 |
Not clear |
| Danielle M Gregor, Wanhong Zuo, Rao Fu, Alex Bekker, Jiang-Hong Y. Elevation of Transient Receptor Potential Vanilloid 1 Function in the Lateral Habenula Mediates Aversive Behaviors in Alcohol-withdrawn Rats. Anesthesiology. vol 130. issue 4. 2020-03-30. PMID:30676422. |
elevation of transient receptor potential vanilloid 1 function in the lateral habenula mediates aversive behaviors in alcohol-withdrawn rats. |
2020-03-30 |
2023-08-13 |
rat |
| Jing Li, Wanhong Zuo, Rao Fu, Guiqin Xie, Amandeep Kaur, Alex Bekker, Jiang Hong Y. High Frequency Electrical Stimulation of Lateral Habenula Reduces Voluntary Ethanol Consumption in Rats. The international journal of neuropsychopharmacology. vol 19. issue 10. 2020-03-09. PMID:27234303. |
increasing evidence indicates that the lateral habenula (lhb) plays an important role in aversion, drug abuse, and depression. |
2020-03-09 |
2023-08-13 |
rat |
| Ou Fu, Yuu Iwai, Masataka Narukawa, Ayako W Ishikawa, Kentaro K Ishii, Ken Murata, Yumiko Yoshimura, Kazushige Touhara, Takumi Misaka, Yasuhiko Minokoshi, Ken-Ichiro Nakajim. Hypothalamic neuronal circuits regulating hunger-induced taste modification. Nature communications. vol 10. issue 1. 2020-02-19. PMID:31594935. |
importantly, these neurons play a key role in modulating preferences for both appetitive and aversive tastes by using distinct pathways projecting to the lateral septum or the lateral habenula, respectively. |
2020-02-19 |
2023-08-13 |
mouse |
| Myunghyun Cheon, Hoyong Park, Hyewon Rhim, ChiHye Chun. Actions of Neuropeptide Y on Synaptic Transmission in the Lateral Habenula. Neuroscience. vol 410. 2020-01-31. PMID:31082535. |
the lateral habenula (lhb) is a brain region that encodes aversive information and is closely related with mood disorders. |
2020-01-31 |
2023-08-13 |
Not clear |
| Massimo Trusel, Alvaro Nuno-Perez, Salvatore Lecca, Harumi Harada, Arnaud L Lalive, Mauro Congiu, Kiwamu Takemoto, Takuya Takahashi, Francesco Ferraguti, Manuel Mamel. Punishment-Predictive Cues Guide Avoidance through Potentiation of Hypothalamus-to-Habenula Synapses. Neuron. vol 102. issue 1. 2019-11-04. PMID:30765165. |
neurons in the lateral habenula (lhb) respond to aversive events as well as to environmental cues predicting them, supporting lhb contribution to cue-punishment association. |
2019-11-04 |
2023-08-13 |
mouse |
| Phillip M Baker, Yingxue Rao, Sheri J Y Mizumor. Transient Input-Specific Neural Plasticity in the Lateral Habenula Facilitates Learning. Neuron. vol 102. issue 1. 2019-10-22. PMID:30946816. |
(2019) demonstrate that circuit-specific plasticity in the lateral habenula is dynamically involved in translating cs-us contingencies into cue-driven avoidance behavior. |
2019-10-22 |
2023-08-13 |
Not clear |
| Ping Gao, Henk J Groenewegen, Louk J M J Vanderschuren, Pieter Voor. Heterogeneous neuronal activity in the lateral habenula after short- and long-term cocaine self-administration in rats. The European journal of neuroscience. vol 47. issue 1. 2019-10-09. PMID:29139213. |
recent studies have implicated the lateral habenula (lhb) in drug-directed behavior, especially its aversive aspects. |
2019-10-09 |
2023-08-13 |
rat |
| Guang-Wei Zhang, Li Shen, Wen Zhong, Ying Xiong, Li I Zhang, Huizhong W Ta. Transforming Sensory Cues into Aversive Emotion via Septal-Habenular Pathway. Neuron. vol 99. issue 5. 2019-08-01. PMID:30122379. |
cell-type-specific screening reveals that glutamatergic ms projections to the lateral habenula (lhb) are responsible for the induction of aversion, which can be antagonized by gabaergic ms projections to lhb. |
2019-08-01 |
2023-08-13 |
Not clear |
| Kristina Valentinova, Anna Tchenio, Massimo Trusel, Joseph A Clerke, Arnaud L Lalive, Stamatina Tzanoulinou, Alessandro Matera, Imane Moutkine, Luc Maroteaux, Rosa C Paolicelli, Andrea Volterra, Camilla Bellone, Manuel Mamel. Morphine withdrawal recruits lateral habenula cytokine signaling to reduce synaptic excitation and sociability. Nature neuroscience. vol 22. issue 7. 2019-07-18. PMID:31209376. |
the lateral habenula encodes aversive stimuli contributing to negative emotional states during drug withdrawal. |
2019-07-18 |
2023-08-13 |
mouse |
| Daniel Knowland, Byung Kook Li. Circuit-based frameworks of depressive behaviors: The role of reward circuitry and beyond. Pharmacology, biochemistry, and behavior. vol 174. 2019-06-24. PMID:29309799. |
on the contrary, the lateral habenula (lhb) is considered to be the aversive center of the brain as it has been shown to encode negative valence. |
2019-06-24 |
2023-08-13 |
Not clear |
| Adam K Klein, Erin M Purvis, Kathy Ayala, Lisette Collins, Jacob T Krug, Matthew S Mayes, Aaron Ettenber. Activation of 5-HT Behavioural brain research. vol 357-358. 2019-03-29. PMID:29660439. |
activation of 5-ht recent work has implicated the lateral habenula (lhb) in the production of anxiogenic and aversive states. |
2019-03-29 |
2023-08-13 |
rat |