| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hai Zhang, Kuan Li, Hong-Sheng Chen, Shuang-Qi Gao, Zhi-Xuan Xia, Jie-Ting Zhang, Fang Wang, Jian-Guo Che. Dorsal raphe projection inhibits the excitatory inputs on lateral habenula and alleviates depressive behaviors in rats. Brain structure & function. vol 223. issue 5. 2019-02-27. PMID:29460052. |
lateral habenula (lhb) plays a crucial role in aversive behaviors and is activated in conditions of depression. |
2019-02-27 |
2023-08-13 |
rat |
| Youichirou Ootsuka, Mazher Mohammed, William W Blessin. Lateral habenula regulation of emotional hyperthermia: mediation via the medullary raphé. Scientific reports. vol 7. issue 1. 2018-12-31. PMID:28642586. |
the lateral habenula (lhb) has an important role in the behavioural response to salient, usually aversive, events. |
2018-12-31 |
2023-08-13 |
Not clear |
| Gabor Egervari, Tanni Rahma. Increased firing of lateral habenula neurons mediates ethanol aversion: potential implications for substance use disorders. The Journal of physiology. vol 595. issue 13. 2018-12-24. PMID:28382659. |
increased firing of lateral habenula neurons mediates ethanol aversion: potential implications for substance use disorders. |
2018-12-24 |
2023-08-13 |
Not clear |
| Limei Zhang, Vito S Hernández, Jerome D Swinny, Anil K Verma, Torsten Giesecke, Andrew C Emery, Kerim Mutig, Luis M Garcia-Segura, Lee E Eide. A GABAergic cell type in the lateral habenula links hypothalamic homeostatic and midbrain motivation circuits with sex steroid signaling. Translational psychiatry. vol 8. issue 1. 2018-12-12. PMID:29479060. |
the lateral habenula (lhb) has a key role in integrating a variety of neural circuits associated with reward and aversive behaviors. |
2018-12-12 |
2023-08-13 |
rat |
| Lauren Faget, Vivien Zell, Elizabeth Souter, Adam McPherson, Reed Ressler, Navarre Gutierrez-Reed, Ji Hoon Yoo, Davide Dulcis, Thomas S Hnask. Opponent control of behavioral reinforcement by inhibitory and excitatory projections from the ventral pallidum. Nature communications. vol 9. issue 1. 2018-12-12. PMID:29487284. |
on the other hand, activation of vp glutamate neurons leads to behavioral avoidance, particularly through projections to the lateral habenula. |
2018-12-12 |
2023-08-13 |
Not clear |
| Sten Grillner, Arndt von Twickel, Brita Robertso. The blueprint of the vertebrate forebrain - With special reference to the habenulae. Seminars in cell & developmental biology. vol 78. 2018-12-11. PMID:29107476. |
the lateral habenula plays a role in the control of dopamine activity in the context of aversive behavior and the converse, a reward situation. |
2018-12-11 |
2023-08-13 |
Not clear |
| Seungwoo Kang, Jing Li, Alex Bekker, Jiang-Hong Y. Rescue of glutamate transport in the lateral habenula alleviates depression- and anxiety-like behaviors in ethanol-withdrawn rats. Neuropharmacology. vol 129. 2018-07-27. PMID:29128307. |
findings from animal and human studies have linked aversive states, including those related to drugs of abuse and depression, to aberrant activity in the lateral habenula (lhb). |
2018-07-27 |
2023-08-13 |
human |
| Avi Shah, Wanhong Zuo, Seungwoo Kang, Jing Li, Rao Fu, Haifeng Zhang, Alex Bekker, Jiang-Hong Y. The lateral habenula and alcohol: Role of glutamate and M-type potassium channels. Pharmacology, biochemistry, and behavior. vol 162. 2018-06-18. PMID:28624587. |
this review will center on the effects of alcohol in the lateral habenula (lhb), an epithalamic structure that connects the forebrain with the midbrain and encodes aversive signaling. |
2018-06-18 |
2023-08-13 |
Not clear |
| Jing Li, Seungwoo Kang, Rao Fu, Liangzhi Wu, Wei Wu, Hongwei Liu, Danielle Gregor, Wanhong Zuo, Alex Bekker, Jiang-Hong Y. Inhibition of AMPA receptor and CaMKII activity in the lateral habenula reduces depressive-like behavior and alcohol intake in rats. Neuropharmacology. vol 126. 2018-06-12. PMID:28865912. |
accumulating evidence has associated depression with hyperactivity of the lateral habenula (lhb), an epithalamic structure in the brain that encodes aversive signals. |
2018-06-12 |
2023-08-13 |
rat |
| Jing Wang, Min Li, Ping Wang, Yunhong Zha, Zhi He, Zicheng L. Inhibition of the lateral habenular CaMKⅡ abolishes naloxone-precipitated conditioned place aversion in morphine-dependent mice. Neuroscience letters. vol 653. 2018-04-30. PMID:28527717. |
we found that inactivation of the lateral habenula (lhb) by microinjection of tetrodotoxin (ttx) abolished naloxone-precipitated conditioned place aversion (cpa) in morphine-dependent mice. |
2018-04-30 |
2023-08-13 |
mouse |
| Daqing Wang, Yi Li, Qiru Feng, Qingchun Guo, Jingfeng Zhou, Minmin Lu. Learning shapes the aversion and reward responses of lateral habenula neurons. eLife. vol 6. 2018-03-05. PMID:28561735. |
learning shapes the aversion and reward responses of lateral habenula neurons. |
2018-03-05 |
2023-08-13 |
mouse |
| Chandni Sheth, Teri M Furlong, Kristen A Keefe, Sharif A Tah. The lateral hypothalamus to lateral habenula projection, but not the ventral pallidum to lateral habenula projection, regulates voluntary ethanol consumption. Behavioural brain research. vol 328. 2018-02-07. PMID:28432009. |
the lateral habenula (lhb) is an epithalamic brain region implicated in aversive processing via negative modulation of midbrain dopamine (da) and serotonin (5-ht) systems. |
2018-02-07 |
2023-08-13 |
Not clear |
| María-José Sánchez-Catalán, Fanny Faivre, Ipek Yalcin, Marc-Antoine Muller, Dominique Massotte, Monique Majchrzak, Michel Barro. Response of the Tail of the Ventral Tegmental Area to Aversive Stimuli. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 42. issue 3. 2018-01-16. PMID:27468916. |
stimulation of the lateral habenula (lhb) inputs to the tvta, or of the tvta itself, induces avoidance behaviors, which suggests a role of the tvta in processing aversive information. |
2018-01-16 |
2023-08-13 |
rat |
| Kerisa Shelton, Kelsie Bogyo, Tinisha Schick, Aaron Ettenber. Pharmacological modulation of lateral habenular dopamine D2 receptors alters the anxiogenic response to cocaine in a runway model of drug self-administration. Behavioural brain research. vol 310. 2017-12-01. PMID:27155504. |
recent research has implicated the lateral habenula (lhb) in the encoding of aversive events including the anxiogenic response to cocaine. |
2017-12-01 |
2023-08-13 |
rat |
| P M Baker, S A Raynor, N T Francis, S J Y Mizumor. Lateral habenula integration of proactive and retroactive information mediates behavioral flexibility. Neuroscience. vol 345. 2017-11-09. PMID:26876779. |
the lateral habenula (lhb) is known to play an important role in signaling aversive or adverse events that have happened or are predicted by cues under pavlovian conditions. |
2017-11-09 |
2023-08-13 |
rat |
| Patricio Ahumada-Galleguillos, Carmen G Lemus, Eugenia Díaz, María Osorio-Reich, Steffen Härtel, Miguel L Conch. Directional asymmetry in the volume of the human habenula. Brain structure & function. vol 222. issue 2. 2017-10-20. PMID:27155991. |
it is remarkable that asymmetries involve the lateral habenula, which in humans is particularly enlarged compared to other vertebrates and plays relevant roles in aversive processing and aversively motivated learning. |
2017-10-20 |
2023-08-13 |
human |
| Shashank Tandon, Kristen A Keefe, Sharif A Tah. Excitation of lateral habenula neurons as a neural mechanism underlying ethanol-induced conditioned taste aversion. The Journal of physiology. vol 595. issue 4. 2017-09-01. PMID:27682823. |
excitation of lateral habenula neurons as a neural mechanism underlying ethanol-induced conditioned taste aversion. |
2017-09-01 |
2023-08-13 |
rat |
| P Leon Brown, Paul D Shepar. Functional evidence for a direct excitatory projection from the lateral habenula to the ventral tegmental area in the rat. Journal of neurophysiology. vol 116. issue 3. 2017-08-28. PMID:27358317. |
the lateral habenula, a phylogenetically conserved epithalamic structure, is activated by aversive stimuli and reward omission. |
2017-08-28 |
2023-08-13 |
rat |
| Frank J Meye, Mariano Soiza-Reilly, Tamar Smit, Marco A Diana, Martin K Schwarz, Manuel Mamel. Shifted pallidal co-release of GABA and glutamate in habenula drives cocaine withdrawal and relapse. Nature neuroscience. vol 19. issue 8. 2017-08-18. PMID:27348214. |
the lateral habenula (lhb) encodes negative stimuli and contributes to aversive withdrawal symptoms. |
2017-08-18 |
2023-08-13 |
mouse |
| Elyssa B Margolis, Howard L Field. Mu Opioid Receptor Actions in the Lateral Habenula. PloS one. vol 11. issue 7. 2017-07-26. PMID:27427945. |
increased activity of lateral habenula (lhb) neurons is correlated with aversive states including pain, opioid abstinence, rodent models of depression, and failure to receive a predicted reward. |
2017-07-26 |
2023-08-13 |
Not clear |