| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Paul Leon Brown, Paul D Shepar. Lesions of the fasciculus retroflexus alter footshock-induced cFos expression in the mesopontine rostromedial tegmental area of rats. PloS one. vol 8. issue 4. 2013-10-22. PMID:23593280. |
the lateral habenula (lhb), an epithalamic structure that forms reciprocal connections with midbrain dopamine neurons, shows the opposite response being activated by reward omission or aversive stimuli and inhibited by reward-predicting cues. |
2013-10-22 |
2023-08-12 |
rat |
| Paul Leon Brown, Paul D Shepar. Lesions of the fasciculus retroflexus alter footshock-induced cFos expression in the mesopontine rostromedial tegmental area of rats. PloS one. vol 8. issue 4. 2013-10-22. PMID:23593280. |
these data confirm the involvement of the lateral habenula in modulating the activity of rostromedial tegmental area neurons in response to mild aversive stimuli and suggest that dopamine input may contribute to footshock- induced activation of cfos expression in the lateral habenula. |
2013-10-22 |
2023-08-12 |
rat |
| Thomas C Jhou, Cameron H Good, Courtney S Rowley, Sheng-Ping Xu, Huikun Wang, Nathan W Burnham, Alexander F Hoffman, Carl R Lupica, Satoshi Ikemot. Cocaine drives aversive conditioning via delayed activation of dopamine-responsive habenular and midbrain pathways. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 17. 2013-06-25. PMID:23616555. |
using electrophysiological recordings in awake rats, we found that some neurons in the lateral habenula (lhb), where activation produces aversive conditioning, exhibited biphasic responses to single doses of intravenous cocaine, with an initial inhibition followed by delayed excitation paralleling cocaine's shift from rewarding to aversive. |
2013-06-25 |
2023-08-12 |
rat |
| Stephan Lammel, Byung Kook Lim, Chen Ran, Kee Wui Huang, Michael J Betley, Kay M Tye, Karl Deisseroth, Robert C Malenk. Input-specific control of reward and aversion in the ventral tegmental area. Nature. vol 491. issue 7423. 2013-01-10. PMID:23064228. |
here we show that, because of differences in synaptic connectivity, activation of inputs to the vta from the laterodorsal tegmentum and the lateral habenula elicit reward and aversion in mice, respectively. |
2013-01-10 |
2023-08-12 |
mouse |
| Alice M Stamatakis, Garret D Stube. Activation of lateral habenula inputs to the ventral midbrain promotes behavioral avoidance. Nature neuroscience. vol 15. issue 8. 2012-10-25. PMID:22729176. |
activation of lateral habenula inputs to the ventral midbrain promotes behavioral avoidance. |
2012-10-25 |
2023-08-12 |
mouse |
| Steven J Shabel, Christophe D Proulx, Anthony Trias, Ryan T Murphy, Roberto Malino. Input to the lateral habenula from the basal ganglia is excitatory, aversive, and suppressed by serotonin. Neuron. vol 74. issue 3. 2012-07-12. PMID:22578499. |
input to the lateral habenula from the basal ganglia is excitatory, aversive, and suppressed by serotonin. |
2012-07-12 |
2023-08-12 |
Not clear |
| Michel Barrot, Johannes Thom. Discovering a new anatomical structure in the brain: implications for neuropsychiatry and therapy. The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry. vol 12 Suppl 1. 2012-03-06. PMID:21905990. |
moreover, it is sensitive to drugs of abuse, to stimulant or arousing drugs, to aversive stimuli and it could also be the main relay between lateral habenula and vta. |
2012-03-06 |
2023-08-12 |
human |
| Alexander Friedman, Elad Lax, Yahav Dikshtein, Lital Abraham, Yakov Flaumenhaft, Einav Sudai, Moshe Ben-Tzion, Gal Yadi. Electrical stimulation of the lateral habenula produces an inhibitory effect on sucrose self-administration. Neuropharmacology. vol 60. issue 2-3. 2011-11-22. PMID:20955718. |
the lateral habenula (lhb) plays a role in prediction of negative reinforcement, punishment and aversive responses. |
2011-11-22 |
2023-08-12 |
rat |
| Bo Li, Joaquin Piriz, Martine Mirrione, ChiHye Chung, Christophe D Proulx, Daniela Schulz, Fritz Henn, Roberto Malino. Synaptic potentiation onto habenula neurons in the learned helplessness model of depression. Nature. vol 470. issue 7335. 2011-03-11. PMID:21350486. |
recent studies in monkeys indicate that neurons in the lateral habenula (lhb), a nucleus that mediates communication between forebrain and midbrain structures, can increase their activity when an animal fails to receive an expected positive reward or receives a stimulus that predicts aversive conditions (that is, disappointment or anticipation of a negative outcome). |
2011-03-11 |
2023-08-12 |
rat |
| Alexander Friedman, Elad Lax, Yahav Dikshtein, Lital Abraham, Yakov Flaumenhaft, Einav Sudai, Moshe Ben-Tzion, Lavi Ami-Ad, Rami Yaka, Gal Yadi. Electrical stimulation of the lateral habenula produces enduring inhibitory effect on cocaine seeking behavior. Neuropharmacology. vol 59. issue 6. 2011-01-20. PMID:20600170. |
the lateral habenula (lhb) is critical for modulation of negative reinforcement, punishment and aversive responses. |
2011-01-20 |
2023-08-12 |
rat |
| Thomas C Jhou, Howard L Fields, Mark G Baxter, Clifford B Saper, Peter C Hollan. The rostromedial tegmental nucleus (RMTg), a GABAergic afferent to midbrain dopamine neurons, encodes aversive stimuli and inhibits motor responses. Neuron. vol 61. issue 5. 2009-04-01. PMID:19285474. |
separate studies have implicated the lateral habenula (lhb) or amygdala-related regions in processing aversive stimuli, but their relationships to each other and to appetitive motivational systems are poorly understood. |
2009-04-01 |
2023-08-12 |
Not clear |
| K S Wilcox, G R Christoph, B A Double, R J Leonzi. Kainate and electrolytic lesions of the lateral habenula: effect on avoidance responses. Physiology & behavior. vol 36. issue 3. 1986-06-11. PMID:3517897. |
kainate and electrolytic lesions of the lateral habenula: effect on avoidance responses. |
1986-06-11 |
2023-08-11 |
rat |
| K S Wilcox, G R Christoph, B A Double, R J Leonzi. Kainate and electrolytic lesions of the lateral habenula: effect on avoidance responses. Physiology & behavior. vol 36. issue 3. 1986-06-11. PMID:3517897. |
male sprague dawley rats (n = 24), which received either bilateral electrolytic lesions, kainic acid lesions or sham treatments in the lateral habenula, were tested for acquisition of a one-way, conditioned avoidance response. |
1986-06-11 |
2023-08-11 |
rat |