| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ruinan Lu, Qian Wang, Jianyong Li, Dengshun Mia. P27 deletion enhances hematopoiesis by paracrine action of IL22 secreted from bone marrow mesenchymal stem cells. American journal of translational research. vol 12. issue 3. 2020-09-28. PMID:32269712. |
to answer this question, we cultured the bm-mscs from wild-type (wt) or p27 knockout (ko) mice, analyzed their proliferation, apoptosis and osteogenesis and harvested their conditioned medium (cm); we also cultured the bone marrow cells (bmcs) with normal medium or cm from wt or ko bm-mscs and analyzed changes of hscs and hpcs and colony forming cells (cfcs). |
2020-09-28 |
2023-08-13 |
mouse |
| Jeung-Hyun Koo, Hyun-Young Jang, Youngyi Lee, Young Jae Moon, Eun Ju Bae, Seok-Kweon Yun, Byung-Hyun Par. Myeloid cell-specific sirtuin 6 deficiency delays wound healing in mice by modulating inflammation and macrophage phenotypes. Experimental & molecular medicine. vol 51. issue 4. 2020-06-08. PMID:31028245. |
consistent with the in vivo wound closure defects observed in the ko mice, keratinocytes and fibroblasts treated with ko macrophage-derived conditioned medium migrated slower than those treated with wild-type macrophage-derived conditioned medium. |
2020-06-08 |
2023-08-13 |
mouse |
| Sami Ben Hamida, Laura-Joy Boulos, Michael McNicholas, Pauline Charbogne, Brigitte Lina Kieffe. Mu opioid receptors in GABAergic neurons of the forebrain promote alcohol reward and drinking. Addiction biology. vol 24. issue 1. 2020-04-02. PMID:29094432. |
further, alcohol-induced conditioned place preference was detected in control but not mor ko mice, indicating that mor is essential for alcohol reward and again, dlx-mor ko recapitulated the mor ko phenotype. |
2020-04-02 |
2023-08-13 |
mouse |
| Mala Ananth, Eleftherios M Hetelekides, John Hamilton, Panayotis K Thano. Dopamine D4 receptor gene expression plays important role in extinction and reinstatement of cocaine-seeking behavior in mice. Behavioural brain research. vol 365. 2020-03-09. PMID:30797855. |
the present study sought to examine the role of drd4 on cocaine-seeking behavior in the conditioned place preference (cpp) test and determine its effects on extinction and reinstatement in adult wild-type (wt), heterozygous (ht), and knockout (ko) mice. |
2020-03-09 |
2023-08-13 |
mouse |
| Tuomo Kiiskinen, Esa R Korpi, Teemu Aitta-Ah. Normal extinction and reinstatement of morphine-induced conditioned place preference in the GluA1-KO mouse line. Behavioural pharmacology. vol 30. issue 5. 2020-03-02. PMID:30376459. |
in line with previous findings, both acquisition and expression of conditioned place preference to morphine (20 mg/kg, subcutaneously) were fully functional in glua1 ko mice compared with wild-type littermate controls (glua1-wt), thus enabling the study of extinction. |
2020-03-02 |
2023-08-13 |
mouse |
| João Lima, Trevor Sharp, David M Bannerman, Stephen B McHug. Enhanced discriminative aversive learning and amygdala responsivity in 5-HT transporter mutant mice. Translational psychiatry. vol 9. issue 1. 2020-01-09. PMID:30996249. |
the present study investigated conditioned aversive learning in 5-htt knockout (ko) mice while simultaneously recording neural network activity (theta oscillations) and hemodynamic responses (tissue oxygen delivery) from the amygdala, a brain region necessary for forming fearful memories. |
2020-01-09 |
2023-08-13 |
mouse |
| Nasna Nassir, Geoffrey J Hyde, Ramamurthy Baska. A telomerase with novel non-canonical roles: TERT controls cellular aggregation and tissue size in Dictyostelium. PLoS genetics. vol 15. issue 6. 2019-11-06. PMID:31237867. |
although, conditioned medium (cm) from countin mutants failed to rescue size in the tert ko, tert ko cm rescued the countin ko phenotype. |
2019-11-06 |
2023-08-13 |
Not clear |
| Francisco J Pavon, Antonia Serrano, Nimish Sidhpura, Ilham Polis, David Stouffer, Fernando Rodriguez de Fonseca, Benjamin F Cravatt, Rémi Martin-Fardon, Loren H Parson. Fatty acid amide hydrolase (FAAH) inactivation confers enhanced sensitivity to nicotine-induced dopamine release in the mouse nucleus accumbens. Addiction biology. vol 23. issue 2. 2019-09-17. PMID:28660730. |
we conducted a microdialysis study to characterize nicotine-induced changes in da and serotonin (5-ht) levels in the nac of faah knockout (ko) mice using a conditioned place preference-like paradigm with three nicotine doses (0.1, 1 and 10 mg/kg, s.c.). |
2019-09-17 |
2023-08-13 |
mouse |
| Kaori Yagishita, Ritsuko Suzuki, Shota Mizuno, Ritsuko Katoh-Semba, Tetsushi Sadakata, Yoshitake Sano, Teiichi Furuichi, Yo Shinod. CAPS2 deficiency affects environmental enrichment-induced adult neurogenesis and differentiation/survival of newborn neurons in the hippocampal dentate gyrus. Neuroscience letters. vol 661. 2018-07-26. PMID:28963059. |
hippocampal levels of brain-derived neurotrophic factor (bdnf) can be used as a physiological ee conditioned marker, and were increased at 14days in the ee condition in both wt and ko mice. |
2018-07-26 |
2023-08-13 |
mouse |
| Jessica K Shaw, Mark J Ferris, Jason L Locke, Zachary D Brodnik, Sara R Jones, Rodrigo A Españ. Hypocretin/orexin knock-out mice display disrupted behavioral and dopamine responses to cocaine. Addiction biology. vol 22. issue 6. 2018-07-16. PMID:27480648. |
the ability of cocaine to elicit reward-related behaviors in mice lacking the hcrt prepro-peptide (hcrt knock-out; ko) and wild-type controls was determined using conditioned place preference. |
2018-07-16 |
2023-08-13 |
mouse |
| Jessica K Shaw, Mark J Ferris, Jason L Locke, Zachary D Brodnik, Sara R Jones, Rodrigo A Españ. Hypocretin/orexin knock-out mice display disrupted behavioral and dopamine responses to cocaine. Addiction biology. vol 22. issue 6. 2018-07-16. PMID:27480648. |
we show that, unlike wild-type mice, hcrt ko mice fail to develop characteristic conditioned place preference for cocaine. |
2018-07-16 |
2023-08-13 |
mouse |
| Yoshio Ohyama, Ju-Hsien Lin, Nattanan Govitvattana, I-Ping Lin, Sundharamani Venkitapathi, Ahmed Alamoudi, Dina Husein, Chunying An, Hak Hotta, Masaru Kaku, Yoshiyuki Mochid. FAM20A binds to and regulates FAM20C localization. Scientific reports. vol 6. 2018-04-09. PMID:27292199. |
on the other hand, extracellular fam20c was absent in the conditioned media of mouse embryonic fibroblasts (mefs) derived from fam20a knock-out (ko) mouse, while it was detected in the media from wt mefs. |
2018-04-09 |
2023-08-13 |
mouse |
| Yoshio Ohyama, Ju-Hsien Lin, Nattanan Govitvattana, I-Ping Lin, Sundharamani Venkitapathi, Ahmed Alamoudi, Dina Husein, Chunying An, Hak Hotta, Masaru Kaku, Yoshiyuki Mochid. FAM20A binds to and regulates FAM20C localization. Scientific reports. vol 6. 2018-04-09. PMID:27292199. |
we also showed that cells with the conditioned media of fam20a wt mefs mineralized, but those with the conditioned media of ko mefs failed to mineralize in vitro. |
2018-04-09 |
2023-08-13 |
mouse |
| R J Taugher, Y Lu, R Fan, A Ghobbeh, C J Kreple, F M Faraci, J A Wemmi. ASIC1A in neurons is critical for fear-related behaviors. Genes, brain, and behavior. vol 16. issue 8. 2018-02-22. PMID:28657172. |
in contrast, in the nucleus accumbens asic1a expression was relatively normal in synasic1a ko mice, and consistent with this observation, cocaine conditioned place preference (cpp) was normal. |
2018-02-22 |
2023-08-13 |
mouse |
| Melissa J Guildford, Anthony V Sacino, Andrew R Tappe. Modulation of ethanol reward sensitivity by nicotinic acetylcholine receptors containing the α6 subunit. Alcohol (Fayetteville, N.Y.). vol 57. 2018-01-03. PMID:27793544. |
we compared binge-like ethanol consumption and ethanol reward sensitivity between knockout (ko) mice that do not express chrna6 (the gene encoding the α6 nachr subunit, the α6 ko line) and wild-type (wt) littermates using the drinking-in-the-dark (did) and conditioned place preference (cpp) assay, respectively. |
2018-01-03 |
2023-08-13 |
mouse |
| Melissa J Guildford, Anthony V Sacino, Andrew R Tappe. Modulation of ethanol reward sensitivity by nicotinic acetylcholine receptors containing the α6 subunit. Alcohol (Fayetteville, N.Y.). vol 57. 2018-01-03. PMID:27793544. |
in the cpp assay, 2.0-g/kg and 3.0-g/kg, but not 0.5-mg/kg, ethanol conditioned a place preference in wt female and male mice, whereas only 2.0-g/kg ethanol conditioned a place preference in α6 ko mice. |
2018-01-03 |
2023-08-13 |
mouse |
| Panayotis K Thanos, Lauren Malave, Foteini Delis, Paul Mangine, Katie Kane, Adam Grunseich, Melissa Vitale, Paul Greengard, Nora D Volko. Knockout of p11 attenuates the acquisition and reinstatement of cocaine conditioned place preference in male but not in female mice. Synapse (New York, N.Y.). vol 70. issue 7. 2017-12-22. PMID:26990537. |
for this purpose we tested wild-type (wt) and p11 knockout (ko) male and female mice for cocaine conditioned place preference (cpp) and its cocaine-induced reinstatement at different abstinence times, after 8 days of extinction and 28 days of being home-caged. |
2017-12-22 |
2023-08-13 |
mouse |
| C P King, L Militello, A Hart, C L St Pierre, E Leung, C L Versaggi, N Roberson, J Catlin, A A Palmer, J B Richards, P J Meye. Cdh13 and AdipoQ gene knockout alter instrumental and Pavlovian drug conditioning. Genes, brain, and behavior. vol 16. issue 7. 2017-12-22. PMID:28387990. |
to examine the role of the cdh13 and its peptide ligand adiponectin (adipoq) in addiction-related behaviors, we assessed cdh13 knockout (ko) rats and adipoq ko mice using intravenous cocaine self-administration and conditioned place preference (cpp) paradigms. |
2017-12-22 |
2023-08-13 |
mouse |
| Mylah Villacorte, Anne-Sophie Delmarcelle, Manon Lernoux, Mahé Bouquet, Pascale Lemoine, Jennifer Bolsée, Lieve Umans, Susana Chuva de Sousa Lopes, Patrick Van Der Smissen, Takako Sasaki, Guido Bommer, Patrick Henriet, Samuel Refetoff, Frédéric P Lemaigre, An Zwijsen, Pierre J Courtoy, Christophe E Pierreu. Thyroid follicle development requires Smad1/5- and endothelial cell-dependent basement membrane assembly. Development (Cambridge, England). vol 143. issue 11. 2017-09-01. PMID:27068110. |
furthermore, conditioned medium (cm) from embryonic endothelial progenitor cells (eepcs) rescued the folliculogenesis defects of both smad1/5(dko) and vegfa(ko) thyroids. |
2017-09-01 |
2023-08-13 |
mouse |
| Rose Chesworth, Robyn M Brown, Jee Hyun Kim, Catherine Ledent, Andrew J Lawrenc. Adenosine 2A receptors modulate reward behaviours for methamphetamine. Addiction biology. vol 21. issue 2. 2016-12-20. PMID:25612195. |
meth conditioned place preference was absent in a2 a ko mice compared with wild-type (wt) littermates. |
2016-12-20 |
2023-08-13 |
mouse |