| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Andrew Sherwood, Marlena Wosiski-Kuhn, Truc Nguyen, Peter C Holland, Bernard Lakaye, Antoine Adamantidis, Alexander W Johnso. The role of melanin-concentrating hormone in conditioned reward learning. The European journal of neuroscience. vol 36. issue 8. 2013-03-06. PMID:22775118. |
pharmacological disruption in control mice and genetic deletion in ko mice impaired crf test performance, suggesting mch-1r is necessary for initiating and maintaining behaviors that are under the control of conditioned reinforcers. |
2013-03-06 |
2023-08-12 |
mouse |
| Kimberly R Smith, Yada Treesukosol, A Brennan Paedae, Robert J Contreras, Alan C Specto. Contribution of the TRPV1 channel to salt taste quality in mice as assessed by conditioned taste aversion generalization and chorda tympani nerve responses. American journal of physiology. Regulatory, integrative and comparative physiology. vol 303. issue 11. 2013-02-07. PMID:23054171. |
using a brief-access taste test, we examined generalization profiles of water-deprived c57bl/6j (wt) and trpv1 knockout (ko) mice conditioned (via licl injection) to avoid 100 μm amiloride-prepared 0.25 m nacl and tested with 0.25 m nacl, sodium gluconate, kcl, nh(4)cl, 6.625 mm citric acid, 0.15 mm quinine, and 0.5 m sucrose. |
2013-02-07 |
2023-08-12 |
mouse |
| Cheng Yin, Shuai Zhou, Li Jiang, Xiaochuan Su. Mechanical injured neurons stimulate astrocytes to express apolipoprotein E through ERK pathway. Neuroscience letters. vol 515. issue 1. 2013-02-04. PMID:22450050. |
the conditioned medium of wild type (wt) primary mouse astrocytes was collected and added into cultured injured apoe knockout (ko) neurons. |
2013-02-04 |
2023-08-12 |
mouse |
| Cheng Yin, Shuai Zhou, Li Jiang, Xiaochuan Su. Mechanical injured neurons stimulate astrocytes to express apolipoprotein E through ERK pathway. Neuroscience letters. vol 515. issue 1. 2013-02-04. PMID:22450050. |
separately, the conditioned medium of injured apoe ko neurons was collected and added into cultured wt astrocytes. |
2013-02-04 |
2023-08-12 |
mouse |
| Alexis W Ary, Debra K Cozzoli, Deborah A Finn, John C Crabbe, Marlin H Dehoff, Paul F Worley, Karen K Szumlinsk. Ethanol up-regulates nucleus accumbens neuronal activity dependent pentraxin (Narp): implications for alcohol-induced behavioral plasticity. Alcohol (Fayetteville, N.Y.). vol 46. issue 4. 2012-09-25. PMID:22444953. |
compared to wild-type mice, narp ko animals: fail to escalate daily intake of high alcohol concentrations under free-access conditions; shift their preference away from high alcohol concentrations with repeated alcohol experience; exhibit a conditioned place-aversion in response to the repeated pairing of 3 g/kg alcohol with a distinct environment and fail to exhibit alcohol-induced locomotor hyperactivity following repeated alcohol treatment. |
2012-09-25 |
2023-08-12 |
mouse |
| Cindy Achat-Mendes, Laurie J Lynch, Katherine A Sullivan, Eric J Vallender, Gregory M Mille. Augmentation of methamphetamine-induced behaviors in transgenic mice lacking the trace amine-associated receptor 1. Pharmacology, biochemistry, and behavior. vol 101. issue 2. 2012-09-24. PMID:22079347. |
to investigate the role of taar1 in the rewarding effects of drugs of abuse, the psychomotor stimulating effects of amphetamine and methamphetamine and the conditioned rewarding effects of methamphetamine and morphine were compared between wt and taar1 ko mice. |
2012-09-24 |
2023-08-12 |
mouse |
| Cindy Achat-Mendes, Laurie J Lynch, Katherine A Sullivan, Eric J Vallender, Gregory M Mille. Augmentation of methamphetamine-induced behaviors in transgenic mice lacking the trace amine-associated receptor 1. Pharmacology, biochemistry, and behavior. vol 101. issue 2. 2012-09-24. PMID:22079347. |
in conditioned place preference (cpp) studies, taar1 ko mice acquired methamphetamine-induced cpp earlier than wt mice and retained cpp longer during extinction training. |
2012-09-24 |
2023-08-12 |
mouse |
| Cindy Achat-Mendes, Laurie J Lynch, Katherine A Sullivan, Eric J Vallender, Gregory M Mille. Augmentation of methamphetamine-induced behaviors in transgenic mice lacking the trace amine-associated receptor 1. Pharmacology, biochemistry, and behavior. vol 101. issue 2. 2012-09-24. PMID:22079347. |
that methamphetamine-but not morphine-induced cpp was augmented in taar1 ko mice suggests a selective role of taar1 in the conditioned reinforcing effects of methamphetamine. |
2012-09-24 |
2023-08-12 |
mouse |
| Meghan C Eddy, Benjamin K Eschle, Darlene Peterson, Nathan Lauras, Robert F Margolskee, Eugene R Dela. A conditioned aversion study of sucrose and SC45647 taste in TRPM5 knockout mice. Chemical senses. vol 37. issue 5. 2012-09-19. PMID:21987728. |
this study reports the results of conditioned aversion studies designed to motivate wild-type (wt) and ko mice to respond to sweet substances. |
2012-09-19 |
2023-08-12 |
mouse |
| Meghan C Eddy, Benjamin K Eschle, Darlene Peterson, Nathan Lauras, Robert F Margolskee, Eugene R Dela. A conditioned aversion study of sucrose and SC45647 taste in TRPM5 knockout mice. Chemical senses. vol 37. issue 5. 2012-09-19. PMID:21987728. |
in contrast, trpm5 ko mice showed a much smaller conditioned aversion to either sweet substance, suggesting a compromised, but not absent, ability to detect sweet taste. |
2012-09-19 |
2023-08-12 |
mouse |
| Meghan C Eddy, Benjamin K Eschle, Darlene Peterson, Nathan Lauras, Robert F Margolskee, Eugene R Dela. A conditioned aversion study of sucrose and SC45647 taste in TRPM5 knockout mice. Chemical senses. vol 37. issue 5. 2012-09-19. PMID:21987728. |
a subsequent conditioned flavor aversion experiment was conducted to determine if trpm5 ko mice were impaired in their ability to learn a conditioned aversion. |
2012-09-19 |
2023-08-12 |
mouse |
| Meghan C Eddy, Benjamin K Eschle, Darlene Peterson, Nathan Lauras, Robert F Margolskee, Eugene R Dela. A conditioned aversion study of sucrose and SC45647 taste in TRPM5 knockout mice. Chemical senses. vol 37. issue 5. 2012-09-19. PMID:21987728. |
in this experiment, ko and wt mice were conditioned to a mixture of sc45647 and amyl acetate (an odor cue). |
2012-09-19 |
2023-08-12 |
mouse |
| Joaquin N Lugo, Amy L Brewster, Corinne M Spencer, Anne E Anderso. Kv4.2 knockout mice have hippocampal-dependent learning and memory deficits. Learning & memory (Cold Spring Harbor, N.Y.). vol 19. issue 5. 2012-08-14. PMID:22505720. |
kv4.2 ko mice also demonstrated a specific deficit in contextual learning in the fear-conditioning test, without impairment in the conditioned stimulus or new context condition. |
2012-08-14 |
2023-08-12 |
mouse |
| Frederique Chaperon, Markus Fendt, Peter H Kelly, Kurt Lingenhoehl, Johannes Mosbacher, Hans-Rudolf Olpe, Peter Schmid, Christine Sturchler, Kevin H McAllister, P Herman van der Putten, Christine E Ge. Gastrin-releasing peptide signaling plays a limited and subtle role in amygdala physiology and aversive memory. PloS one. vol 7. issue 4. 2012-08-07. PMID:22509372. |
grpr ko mice also failed to show differences in fear expression and extinction after multiple-trial fear conditioning, and there were no differences in conditioned taste aversion or gustatory neophobia. |
2012-08-07 |
2023-08-12 |
mouse |
| Saara Nuutinen, Minnamaija Lintunen, Jenni Vanhanen, Tiia Ojala, Stanislav Rozov, Pertti Panul. Evidence for the role of histamine H3 receptor in alcohol consumption and alcohol reward in mice. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 36. issue 10. 2012-06-04. PMID:21654737. |
impairment in reward mechanisms in h3r ko mice was confirmed by the lack of alcohol-evoked conditioned place preference. |
2012-06-04 |
2023-08-12 |
mouse |
| Teresa Femenía, Jorge Manzanare. Increased ethanol intake in prodynorphin knockout mice is associated to changes in opioid receptor function and dopamine transmission. Addiction biology. vol 17. issue 2. 2012-05-08. PMID:21966993. |
handling-induced convulsion (hic) associated to alcohol, alcohol-induced loss of righting reflex (lorr), hypothermic effects in response to acute ethanol challenge, blood ethanol levels (bels), conditioned place preference, voluntary ethanol consumption and preference, tyrosine hydroxylase (th), dopamine transporter (dat) and proenkephalin (penk) gene expression, and µ-, δ- and κ-opioid agonist-stimulated [s(35) ]- guanosine 5'-triphosphate-binding autoradiography were studied in prodynorphin knockout (pdyn ko) and wild-type (wt) mice. |
2012-05-08 |
2023-08-12 |
mouse |
| William J Giardino, Davelle L Cocking, Simranjit Kaur, Christopher L Cunningham, Andrey E Ryabini. Urocortin-1 within the centrally-projecting Edinger-Westphal nucleus is critical for ethanol preference. PloS one. vol 6. issue 10. 2012-03-26. PMID:22046429. |
results from these studies revealed that (1) genetic deletion of ucn1 dampened etoh preference only in mice with an intact ewcp, but not in mice that received lesion of the ewcp, (2) lesion of the ewcp dampened etoh intake in ucn1 ko and wt mice, but dampened etoh preference only in wt mice expressing ucn1, and (3) genetic deletion of ucn1 or crf-r2 abolished the conditioned rewarding effects of etoh, but deletion of ucn1 had no effect on the conditioned aversive effects of etoh. |
2012-03-26 |
2023-08-12 |
mouse |
| Marguerite C Camp, Michael Feyder, Jessica Ihne, Benjamin Palachick, Benita Hurd, Rose-Marie Karlsson, Bianca Noronha, Yi-Chyan Chen, Marcelo P Coba, Seth G N Grant, Andrew Holme. A novel role for PSD-95 in mediating ethanol intoxication, drinking and place preference. Addiction biology. vol 16. issue 3. 2011-12-02. PMID:21309945. |
here, we evaluated knockout (ko) mice lacking psd-95 for multiple measures of sensitivity to the acute intoxicating effects of etoh (ataxia, hypothermia, sedation/hypnosis), etoh drinking under conditions of free access and following deprivation, acquisition and long-term retention of etoh conditioned place preference (cpp) (and lithium chloride-induced conditioned taste aversion), and intoxication-potentiating responses to nmdar antagonism. |
2011-12-02 |
2023-08-12 |
mouse |
| Drew D Kiraly, Fouad Lemtiri-Chlieh, Eric S Levine, Richard E Mains, Betty A Eippe. Kalirin binds the NR2B subunit of the NMDA receptor, altering its synaptic localization and function. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 35. 2011-10-21. PMID:21880917. |
additionally, we demonstrate that the genotypic differences in conditioned place preference and passive avoidance learning seen in kal7(ko) mice are abrogated when animals are treated with an nr2b-specific antagonist during conditioning. |
2011-10-21 |
2023-08-12 |
mouse |
| Craig S Moore, Richard Milner, Akiko Nishiyama, Ricardo F Frausto, David R Serwanski, Roberto R Pagarigan, J Lindsay Whitton, Robert H Miller, Stephen J Crocke. Astrocytic tissue inhibitor of metalloproteinase-1 (TIMP-1) promotes oligodendrocyte differentiation and enhances CNS myelination. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 16. 2011-06-30. PMID:21508247. |
we also determined that a2b5(+) oligodendrocyte progenitors grown in conditioned media derived from timp-1 ko primary glial cultures resulted in reduced differentiation of mature o1(+) oligodendrocytes. |
2011-06-30 |
2023-08-12 |
mouse |