| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Thomas L Estus, Shilpa Choudhary, Carol C Pilbea. Prostaglandin-mediated inhibition of PTH-stimulated β-catenin signaling in osteoblasts by bone marrow macrophages. Bone. vol 85. 2016-12-13. PMID:26851123. |
primary calvarial osteoblasts (pobs) were co-cultured with conditioned medium (cm) from rankl-treated wild type (wt) bmms, which make the inhibitory factor, and cox2 knockout (ko) bmms, which do not. |
2016-12-13 |
2023-08-13 |
human |
| Anthony Sclafani, Hermann Koepsell, Karen Ackrof. SGLT1 sugar transporter/sensor is required for post-oral glucose appetition. American journal of physiology. Regulatory, integrative and comparative physiology. vol 310. issue 7. 2016-08-08. PMID:26791832. |
an initial experiment revealed that both ko and wt mice maintained on a very low-carbohydrate diet display normal preferences for saccharin, which was used in the flavored conditioned stimulus (cs) solutions. |
2016-08-08 |
2023-08-13 |
mouse |
| Shilpa Choudhary, Alexandra Goetjen, Thomas Estus, Christian E Jacome-Galarza, Hector L Aguila, Joseph Lorenzo, Carol Pilbea. Serum Amyloid A3 Secreted by Preosteoclasts Inhibits Parathyroid Hormone-stimulated cAMP Signaling in Murine Osteoblasts. The Journal of biological chemistry. vol 291. issue 8. 2016-07-01. PMID:26703472. |
conditioned medium (cm) from rankl-treated wt, but not ko, bmms blocked pth-stimulated camp production in pobs. |
2016-07-01 |
2023-08-13 |
mouse |
| Ruth I Wood, Allison T Knoll, Pat Levit. Social housing conditions and oxytocin and vasopressin receptors contribute to ethanol conditioned social preference in female mice. Physiology & behavior. vol 151. 2016-06-28. PMID:26282397. |
the study compared wild-type (wt) and knock-out (ko) females lacking either oxtr or avpr1a in a conditioned social preference (csp) test. |
2016-06-28 |
2023-08-13 |
mouse |
| Mary Sourial, Laurie C Doerin. Astrocyte-Secreted Factors Selectively Alter Neural Stem and Progenitor Cell Proliferation in the Fragile X Mouse. Frontiers in cellular neuroscience. vol 10. 2016-05-31. PMID:27242437. |
we used the neural colony forming cell assay to determine the effect of astrocyte conditioned media (acm) on the generation of neurospheres originating from either progenitor cells or functional stem cells in the knock out (ko) fragile x mouse model. |
2016-05-31 |
2023-08-13 |
mouse |
| Rémi Legastelois, Emmanuel Darcq, Scott A Wegner, Paul J Lombroso, Dorit Ro. Striatal-enriched protein tyrosine phosphatase controls responses to aversive stimuli: implication for ethanol drinking. PloS one. vol 10. issue 5. 2016-04-18. PMID:25992601. |
to further test this hypothesis, we measured the responses of step ko and wt mice to lithium-induced conditioned place aversion (cpa) and found that whereas wt mice developed lithium place aversion, step ko mice did not. |
2016-04-18 |
2023-08-13 |
mouse |
| Sarah S Sanjakdar, Pretal P Maldoon, Michael J Marks, Darlene H Brunzell, Uwe Maskos, J Michael McIntosh, M Scott Bowers, M Imad Dama. Differential roles of α6β2* and α4β2* neuronal nicotinic receptors in nicotine- and cocaine-conditioned reward in mice. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 40. issue 2. 2015-12-18. PMID:25035086. |
importantly, these effects did not generalize as α6 ko showed both a conditioned place aversion to lithium chloride as well as cpp to palatable food. |
2015-12-18 |
2023-08-13 |
mouse |
| Prescott T Leach, Justin W Kenney, Thomas J Goul. Stronger learning recruits additional cell-signaling cascades: c-Jun-N-terminal kinase 1 (JNK1) is necessary for expression of stronger contextual fear conditioning. Neurobiology of learning and memory. vol 118. 2015-11-10. PMID:25543025. |
wildtype (wt), jnk1 heterozygous (het), and jnk1 knockout (ko) mice were fear conditioned with 1 trial, 2 trials, or 4 trials. |
2015-11-10 |
2023-08-13 |
mouse |
| Zsuzsanna Callaerts-Vegh, Tariq Ahmed, Ben Vermaercke, Peter Marynen, Detlef Balschun, Guy Froyen, Rudi D'Hoog. Nxf7 deficiency impairs social exploration and spatio-cognitive abilities as well as hippocampal synaptic plasticity in mice. Frontiers in behavioral neuroscience. vol 9. 2015-07-28. PMID:26217206. |
furthermore, while we observed no difference in a nose poke suppression in an conditioned emotional response (cer) protocol, nxf7 ko mice were impaired in discriminating between differentially reinforced cues in an auditory fear conditioning protocol. |
2015-07-28 |
2023-08-13 |
mouse |
| Chris M Friemel, Andreas Zimmer, Miriam Schneide. The CB1 receptor as an important mediator of hedonic reward processing. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 39. issue 10. 2015-04-15. PMID:24718372. |
finally, presentation of a conditioned reward cue was found to induce striatal fosb/Δfosb expression in wt mice, but not in ko mice, indicating a reduced stimulation of reward-related brain regions in conditioned ko mice by odor presentation. |
2015-04-15 |
2023-08-13 |
mouse |
| Michael G Tordoff, Hillary T Ellis, Tiffany R Aleman, Arnelle Downing, Philippe Marambaud, J Kevin Foskett, Rachel M Dana, Stuart A McCaughe. Salty taste deficits in CALHM1 knockout mice. Chemical senses. vol 39. issue 6. 2015-02-02. PMID:24846212. |
here, we evaluated several salty taste-related phenotypes of calhm1 knockout (ko) mice and their wild-type (wt) controls: 1) in a conditioned aversion test, calhm1 wt and ko mice had similar nacl avoidance thresholds. |
2015-02-02 |
2023-08-13 |
mouse |
| Amine Bahi, Virginie Tolle, Jean-Alain Fehrentz, Luc Brunel, Jean Martinez, Catherine-Laure Tomasetto, Sherif M Kara. Ghrelin knockout mice show decreased voluntary alcohol consumption and reduced ethanol-induced conditioned place preference. Peptides. vol 43. 2014-08-19. PMID:23428971. |
for this purpose ethanol-induced conditioned place preference (cpp), ethanol-induced locomotor stimulation and voluntary ethanol consumption in a two-bottle choice drinking paradigm were examined under conditions where ghrelin and its receptor were blocked, either using ghrelin knockout (ko) mice or the specific ghrelin receptor (ghs-r1a) antagonist "jmv2959". |
2014-08-19 |
2023-08-12 |
mouse |
| Joaquin N Lugo, Gregory D Smith, Jessica B Morrison, Jessika Whit. Deletion of PTEN produces deficits in conditioned fear and increases fragile X mental retardation protein. Learning & memory (Cold Spring Harbor, N.Y.). vol 20. issue 12. 2014-07-01. PMID:24241749. |
we found that ns-pten ko mice had deficits in contextual learning and trace conditioning, but did not have deficits in the ability to learn a conditioned stimulus. |
2014-07-01 |
2023-08-12 |
mouse |
| Haohong Li, Yezheng Tao, Li Ma, Xing Liu, Lan M. β-Arrestin-2 inhibits preference for alcohol in mice and suppresses Akt signaling in the dorsal striatum. Neuroscience bulletin. vol 29. issue 5. 2014-05-02. PMID:23839051. |
in this study, we investigated the role of β-arrestin-2 in alcohol preference using the two-bottle choice and conditioned place preference procedures in wild-type (wt) and β-arrestin-2 knockout (ko) mice. |
2014-05-02 |
2023-08-12 |
mouse |
| Rose Chesworth, Robyn M Brown, Jee Hyun Kim, Andrew J Lawrenc. The metabotropic glutamate 5 receptor modulates extinction and reinstatement of methamphetamine-seeking in mice. PloS one. vol 8. issue 7. 2014-02-03. PMID:23861896. |
mglu5 knockout (ko) mice were tested in intravenous self-administration, conditioned place preference and locomotor sensitization. |
2014-02-03 |
2023-08-12 |
mouse |
| Rose Chesworth, Robyn M Brown, Jee Hyun Kim, Andrew J Lawrenc. The metabotropic glutamate 5 receptor modulates extinction and reinstatement of methamphetamine-seeking in mice. PloS one. vol 8. issue 7. 2014-02-03. PMID:23861896. |
development of conditioned place preference and locomotor sensitization were intact in ko mice; however, conditioned hyperactivity to the context previously paired with drug was elevated in ko mice. |
2014-02-03 |
2023-08-12 |
mouse |
| Ashley M Blouin, Sungho Han, Anne M Pearce, Kailun Cheng, Jongah J Lee, Alexander W Johnson, Chuansong Wang, Matthew J During, Peter C Holland, Yavin Shaham, Jay M Baraban, Irving M Ret. Role of medial prefrontal cortex Narp in the extinction of morphine conditioned place preference. Learning & memory (Cold Spring Harbor, N.Y.). vol 20. issue 2. 2013-07-01. PMID:23322555. |
narp knockout (ko) mice demonstrate an impaired extinction of morphine conditioned place preference (cpp). |
2013-07-01 |
2023-08-12 |
mouse |
| Qi Yang, Bin Feng, Kun Zhang, Yan-yan Guo, Shui-bing Liu, Yu-mei Wu, Xiao-qiang Li, Ming-gao Zha. Excessive astrocyte-derived neurotrophin-3 contributes to the abnormal neuronal dendritic development in a mouse model of fragile X syndrome. PLoS genetics. vol 8. issue 12. 2013-05-09. PMID:23300470. |
furthermore, astrocytic conditioned medium (acm) from ko astrocytes inhibited proper dendritic growth of both wild-type (wt) and ko neurons. |
2013-05-09 |
2023-08-12 |
mouse |
| P Olausson, D V Venkitaramani, T D Moran, M W Salter, J R Taylor, P J Lombros. The tyrosine phosphatase STEP constrains amygdala-dependent memory formation and neuroplasticity. Neuroscience. vol 225. 2013-04-16. PMID:22885232. |
here we demonstrate that step ko mice also display augmented fear conditioning as measured by an enhancement in conditioned suppression of instrumental response when a fear-associated conditioned stimulus was presented. |
2013-04-16 |
2023-08-12 |
mouse |
| Andrew Sherwood, Marlena Wosiski-Kuhn, Truc Nguyen, Peter C Holland, Bernard Lakaye, Antoine Adamantidis, Alexander W Johnso. The role of melanin-concentrating hormone in conditioned reward learning. The European journal of neuroscience. vol 36. issue 8. 2013-03-06. PMID:22775118. |
here we examined whether targeted-deletion of the mch receptor (mch-1r) in gene-targeted heterozygote and knockout mice (ko), or systemic treatment with pharmacological agents designed to antagonise mch-1r in c57bl/6j mice would disrupt two putative consequences of reward learning that rely on different neural circuitries: conditioned reinforcement (crf) and pavlovian-instrumental transfer (pit). |
2013-03-06 |
2023-08-12 |
mouse |