| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hailei Yu, Bing Xie, Jingjing Zhang, Yixiao Luo, Ewa Galaj, Xiuning Zhang, Qianchao Shen, Yi Liu, Bin Cong, Di Wen, Chunling M. The role of circTmeff-1 in incubation of context-induced morphine craving. Pharmacological research. vol 170. 2021-10-18. PMID:34116208. |
in the present study, we trained mice to morphine conditioned place preference (cpp) and collected the nucleus accumbens (nac) sections on abstinence day 1 (ad1) and day 14 (ad14) for rna-sequencing. |
2021-10-18 |
2023-08-13 |
mouse |
| Elaheh Soleimanpour, Jorge R Bergado Acosta, Peter Landgraf, Dana Mayer, Evelyn Dankert, Daniela C Dieterich, Markus Fend. Regulation of CREB Phosphorylation in Nucleus Accumbens after Relief Conditioning. Cells. vol 10. issue 2. 2021-10-12. PMID:33530478. |
our analyses revealed that relief conditioned rats had higher creb phosphorylation in nac 6 h after conditioning than pseudo conditioned rats. |
2021-10-12 |
2023-08-13 |
rat |
| Hossein Khaleghzadeh-Ahangar, Abbas Haghparas. Cannabinoid receptor modulation changes the accumbal neuronal responses to morphine in the reinstatement of morphine-induced conditioned place preference. Addiction biology. vol 25. issue 6. 2021-09-28. PMID:31436887. |
although cannabinoids can modulate different stages of morphine encounter such as the reinstatement of morphine-induced conditioned place preference (cpp), there is no evidence for the nac neurons' response to prove it. |
2021-09-28 |
2023-08-13 |
rat |
| Magdalena Sustkova-Fiserova, Nina Puskina, Tereza Havlickova, Marek Lapka, Kamila Syslova, Veronika Pohorala, Chrysostomos Charalambou. Ghrelin receptor antagonism of fentanyl-induced conditioned place preference, intravenous self-administration, and dopamine release in the nucleus accumbens in rats. Addiction biology. vol 25. issue 6. 2021-09-28. PMID:31696597. |
therefore, the aim of our study was to clarify whether the ghs-r1a antagonist jmv2959 could reduce the fentanyl-induced conditioned place preference (cpp), the fentanyl intravenous self-administration (ivsa), and the tendency to relapse, but also whether jmv2959 could significantly influence the fentanyl-induced dopamine efflux in the nucleus accumbens (nac) in rats, that importantly participates in opioids' reinforcing effects. |
2021-09-28 |
2023-08-13 |
rat |
| Nazanin Kahvandi, Zahra Ebrahimi, Seyed Asaad Karimi, Siamak Shahidi, Iraj Salehi, Marzieh Naderishahab, Abdolrahman Sarih. The effect of the mGlu8 receptor agonist, (S)-3,4-DCPG on acquisition and expression of morphine-induced conditioned place preference in male rats. Behavioral and brain functions : BBF. vol 17. issue 1. 2021-09-02. PMID:33612106. |
the aim of the present study was to evaluate the role of mglu8 receptors within the nac in the acquisition and expression phases of morphine induced conditioned place preference (cpp). |
2021-09-02 |
2023-08-13 |
rat |
| Claire E Stelly, Kasey S Girven, Merridee J Lefner, Kaitlyn M Fonzi, Matthew J Wana. Dopamine release and its control over early Pavlovian learning differs between the NAc core and medial NAc shell. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 46. issue 10. 2021-08-27. PMID:33452431. |
pharmacological experiments found that dopamine-sensitive conditioned responding emerged in the nac core before the medial nac shell. |
2021-08-27 |
2023-08-13 |
rat |
| Constanza Garcia-Keller, Cora Smiley, Cara Monforton, Samantha Melton, Peter W Kalivas, Justin Gas. N-Acetylcysteine treatment during acute stress prevents stress-induced augmentation of addictive drug use and relapse. Addiction biology. vol 25. issue 5. 2021-08-11. PMID:31282090. |
these data support using daily nac treatment during or immediately after experiencing a strong acute stress to prevent subsequent conditioned stress responding, in particular relapse and cognitive deficits induced by stress-conditioned stimuli. |
2021-08-11 |
2023-08-13 |
rat |
| Hassan Jorjani, Marzieh Joneidi, Abbas Ali Vafaei, Ali Rashidy-Pour, Hamidreza Sameni, Ahmad Reza Bandegi, Behpour Yousefi, Hossein Miladi-Gorj. Microinjection of the BDNF receptor antagonist ANA-12 into the nucleus accumbens and medial-prefrontal cortex attenuates morphine-induced reward memory, and alterations of BDNF levels and apoptotic cells in rats. Pharmacology, biochemistry, and behavior. vol 201. 2021-08-10. PMID:33444602. |
this study was designed to examine the effects of intra- nucleus accumbens (nac) of bdnf receptor antagonist ana-12 on the acquisition and expression and intra- medial-prefrontal cortex (mpfc) of ana-12 on the extinction and reinstatement of morphine-induced conditioned place preference (cpp) and also bdnf levels and apoptotic neurons in the nac and mpfc of rats. |
2021-08-10 |
2023-08-13 |
rat |
| Jiao Tang, Rui Chen, Lingling Wang, Lu Yu, Dandan Zuo, Guiyun Cui, Xiaoqian Gon. Melatonin Attenuates Thrombin-induced Inflammation in BV2 Cells and Then Protects HT22 Cells from Apoptosis. Inflammation. vol 43. issue 5. 2021-07-15. PMID:32705396. |
in further experiments investigating the protection conferred by melatonin, incubating ht22 cells with conditioned medium (cm) from thrombin-stimulated microglia induced ht22 cell apoptosis, and this effect was reversed after treating cm with either melatonin or n-acetyl-l-cysteine (nac). |
2021-07-15 |
2023-08-13 |
Not clear |
| Andrew Chih Wei Huang, Ying Hao Yu, Alan Bo Han He, Chen Yin O. Interactions between prelimbic cortex and basolateral amygdala contribute to morphine-induced conditioned taste aversion in conditioning and extinction. Neurobiology of learning and memory. vol 172. 2021-07-14. PMID:32407964. |
the consequences of exciting or destroying the prelimbic cortex (prl) or the basolateral amygdala (bla) remain unclear, including the effects on morphine-induced conditioned taste aversion (cta) in the conditioning and extinction phases, plasma corticosterone (cort) levels, and c-fos/p-erk expressions in the subareas of the medial prefrontal cortex (i.e., prl, infralimbic cortex [il], cingulate cortex 1 [cg1]), basolateral amygdala (bla), central amygdala (cea), hippocampus (i.e., ca1, ca2, ca3, and dentate gyrus [dg]), nucleus accumbens (nac), lateral hypothalamus (lh), and piriform cortex (pc). |
2021-07-14 |
2023-08-13 |
Not clear |
| Gabriella Margetts-Smith, Anastasia I Macnaghten, Leonie S Brebner, Joseph J Ziminski, Meike C Sieburg, Jeffrey W Grimm, Hans S Crombag, Eisuke Koy. Acute, but not longer-term, exposure to environmental enrichment attenuates Pavlovian cue-evoked conditioned approach and Fos expression in the prefrontal cortex in mice. The European journal of neuroscience. vol 53. issue 8. 2021-06-29. PMID:33565633. |
we therefore measured the effects of acute/intermittent (1 day or 6 day of ee prior to test day) versus chronic (ee throughout conditioning lasting until test day) ee on the ability of a pavlovian sucrose cue to elicit sucrose seeking (conditioned approach) and fos expression in the medial prefrontal cortex (mpfc), orbitofrontal cortex (ofc), and nucleus accumbens (nac) in mice. |
2021-06-29 |
2023-08-13 |
mouse |
| Aimilia Lydia Kalafateli, Cajsa Aranäs, Elisabet Jerlha. Activation of the amylin pathway modulates cocaine-induced activation of the mesolimbic dopamine system in male mice. Hormones and behavior. vol 127. 2021-06-25. PMID:33166561. |
we therefore explored in male mice, the effects of systemic administration of sct on cocaine-induced locomotor stimulation, dopamine release in the nac and cocaine reward, as well as reward-dependent memory of cocaine, in the conditioned place preference (cpp) paradigm. |
2021-06-25 |
2023-08-13 |
mouse |
| Elahe Khosrowabadi, Saeideh Karimi-Haghighi, Shole Jamali, Abbas Haghparas. Differential Roles of Intra-accumbal Orexin Receptors in Acquisition and Expression of Methamphetamine-Induced Conditioned Place Preference in the Rats. Neurochemical research. vol 45. issue 9. 2021-06-08. PMID:32643036. |
in the present study, the conditioned place preference (cpp) paradigm was used to evaluate the role of oxrs in the nac in the acquisition and expression of methamphetamine (meth)-induced cpp. |
2021-06-08 |
2023-08-13 |
rat |
| Atefeh Bakhtazad, Nasim Vousooghi, Mohammad Nasehi, Nima Sanadgol, Behzad Garmabi, Mohammad Reza Zarrindas. The effect of microinjection of CART 55-102 into the nucleus accumbens shell on morphine-induced conditioned place preference in rats: Involvement of the NMDA receptor. Peptides. vol 129. 2021-06-07. PMID:32335205. |
here, we evaluated whether intra-nucleus accumbens (nac) shell infusions of cart induces conditioned place preference (cpp) or conditioned place aversion (cpa) and affects morphine reward. |
2021-06-07 |
2023-08-13 |
rat |
| Sunny Zhihong Jiang, Sean Sweat, Sam P Dahlke, Kathleen Loane, Gunner Drossel, Wenqin Xu, Hugo A Tejeda, Charles R Gerfen, Lee E Eide. Cocaine-Dependent Acquisition of Locomotor Sensitization and Conditioned Place Preference Requires D1 Dopaminergic Signaling through a Cyclic AMP, NCS-Rapgef2, ERK, and Egr-1/Zif268 Pathway. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 41. issue 4. 2021-03-26. PMID:33268547. |
ncs-rapgef2 gene deletion in the nac in adult mice, using adeno-associated virus-mediated expression of cre recombinase, eliminated cocaine-induced erk phosphorylation and egr-1/zif268 upregulation in d1-medium spiny neurons and cocaine-induced behaviors, including locomotor sensitization and conditioned place preference. |
2021-03-26 |
2023-08-13 |
mouse |
| Sunny Zhihong Jiang, Sean Sweat, Sam P Dahlke, Kathleen Loane, Gunner Drossel, Wenqin Xu, Hugo A Tejeda, Charles R Gerfen, Lee E Eide. Cocaine-Dependent Acquisition of Locomotor Sensitization and Conditioned Place Preference Requires D1 Dopaminergic Signaling through a Cyclic AMP, NCS-Rapgef2, ERK, and Egr-1/Zif268 Pathway. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 41. issue 4. 2021-03-26. PMID:33268547. |
our results indicate that ncs-rapgef2 signaling to erk in dopamine d1 receptor-expressing neurons in the nac, but not in corticolimbic areas, contributes to cocaine-induced locomotor sensitization and conditioned place preference. |
2021-03-26 |
2023-08-13 |
mouse |
| Inês M Amaral, Cristina Lemos, Isabella Cera, Georg Dechant, Alex Hofer, Rana El Rawa. Involvement of cAMP-Dependent Protein Kinase in the Nucleus Accumbens in Cocaine Versus Social Interaction Reward. International journal of molecular sciences. vol 22. issue 1. 2021-03-25. PMID:33396297. |
the effects of pka inhibition in the nac on the expression of concurrent conditioned place preference (cpp) for cocaine (drug) and social interaction (natural reward) in rats were evaluated. |
2021-03-25 |
2023-08-13 |
rat |
| Shuang-Qi Gao, Hai Zhang, Jin-Gang He, Hui-Ling Zheng, Pei-Wei Zhang, Jun-Feng Xu, Zu-Cheng Shen, Huan-Huan Zhao, Fang Wang, Zhuang-Li Hu, Jian-Guo Che. Neuronal HMGB1 in nucleus accumbens regulates cocaine reward memory. Addiction biology. vol 25. issue 2. 2021-02-16. PMID:31056833. |
gain and loss of hmgb1 in the nac bidirectionally regulate cocaine-induced conditioned place preference. |
2021-02-16 |
2023-08-13 |
Not clear |
| Edita Navratilova, Kelsey Nation, Bethany Remeniuk, Volker Neugebauer, Kirsty Bannister, Anthony H Dickenson, Frank Porrec. Selective modulation of tonic aversive qualities of neuropathic pain by morphine in the central nucleus of the amygdala requires endogenous opioid signaling in the anterior cingulate cortex. Pain. vol 161. issue 3. 2021-02-08. PMID:31725062. |
right, but not left, cea morphine produced conditioned place preference (cpp) and increased extracellular dopamine in the nac selectively in snl rats, suggesting relief of aversive qualities of ongoing pain. |
2021-02-08 |
2023-08-13 |
rat |
| Urszula Skupio, Magdalena Tertil, Wiktor Bilecki, Justyna Barut, Michal Korostynski, Slawomir Golda, Lucja Kudla, Lucja Wiktorowska, Joanna E Sowa, Marcin Siwiec, Bartosz Bobula, Katarzyna Pels, Krzysztof Tokarski, Grzegorz Hess, Blazej Ruszczycki, Grzegorz Wilczynski, Ryszard Przewlock. Astrocytes determine conditioned response to morphine via glucocorticoid receptor-dependent regulation of lactate release. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 45. issue 2. 2020-12-28. PMID:31254970. |
specifically, we show that targeted knockdown of the gr in the nac astrocytes enhanced conditioned responses to morphine, with a concomitant inhibition of morphine-induced neuronal excitability and plasticity. |
2020-12-28 |
2023-08-13 |
mouse |