| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kuisheng Sun, Feng Wang, Lin Ma, Xiaofan Ren, Chun Zhang, Weifang Rong, Tao Su. Genetic knockout of the G protein-coupled estrogen receptor 1 facilitates the acquisition of morphine-induced conditioned place preference and aversion in mice. Biochemical and biophysical research communications. vol 525. issue 4. 2020-12-28. PMID:32184017. |
our study used gper1 knockout (gper1 ko) and wild-type (wt) mice to compare the sensitivity differences of morphine- and sucrose-induced conditioned place preference (cpp) and naloxone-induced conditioned place aversion (cpa), and differences in dopamine (da) content in the nucleus accumbens (nac) were determined by high performance liquid chromatography (hplc). |
2020-12-28 |
2023-08-13 |
mouse |
| Sabyasachi Dash, Muthukumar Balasubramaniam, Freddyson J Martínez-Rivera, Arthur Godino, Emily G Peck, Srinivas Patnaik, Mrutyunjay Suar, Erin S Calipari, Eric J Nestler, Fernando Villalta, Chandravanu Dash, Jui Pandhar. Cocaine-regulated microRNA miR-124 controls poly (ADP-ribose) polymerase-1 expression in neuronal cells. Scientific reports. vol 10. issue 1. 2020-12-21. PMID:32641757. |
consistent with this finding, mir-124 expression was also significantly reduced in the nac of animals conditioned for cocaine place preference. |
2020-12-21 |
2023-08-13 |
mouse |
| Jacqueline F McGinty, James M Oti. Heterogeneity in the Paraventricular Thalamus: The Traffic Light of Motivated Behaviors. Frontiers in behavioral neuroscience. vol 14. 2020-11-13. PMID:33177999. |
although the function of pvt in influencing reward-seeking is poorly understood, recent studies show that forebrain and hypothalamic inputs to, and nucleus accumbens (nac) and amygdalar outputs from, pvt are strongly implicated in pvt responses to conditioned and appetitive or aversive stimuli that determine whether an animal will approach or avoid specific rewards. |
2020-11-13 |
2023-08-13 |
Not clear |
| Lili Niu, Yanchen Guo, Zhengrong Lin, Zhe Shi, Tianyuan Bian, Lin Qi, Long Meng, Anthony A Grace, Hairong Zheng, Ti-Fei Yua. Noninvasive ultrasound deep brain stimulation of nucleus accumbens induces behavioral avoidance. Science China. Life sciences. vol 63. issue 9. 2020-11-02. PMID:32180109. |
our results show that an acute ultrasound stimulation on the nac, rather than the visual cortex or auditory cortex, led to a pronounced avoidance behavior, while repeated nac ultrasound stimulation resulted in an obvious conditioned place aversion with changes in synaptic protein (glua1/2 subunit) expression. |
2020-11-02 |
2023-08-13 |
mouse |
| Lili Niu, Yanchen Guo, Zhengrong Lin, Zhe Shi, Tianyuan Bian, Lin Qi, Long Meng, Anthony A Grace, Hairong Zheng, Ti-Fei Yua. Noninvasive ultrasound deep brain stimulation of nucleus accumbens induces behavioral avoidance. Science China. Life sciences. vol 63. issue 9. 2020-11-02. PMID:32180109. |
notably, nac ultrasound stimulation suppressed the morphine-induced conditioned place preference. |
2020-11-02 |
2023-08-13 |
mouse |
| Emanuele Claudio Latagliata, Stefano Puglisi-Allegra, Rossella Ventura, Simona Cabi. Norepinephrine in the Medial Pre-frontal Cortex Supports Accumbens Shell Responses to a Novel Palatable Food in Food-Restricted Mice Only. Frontiers in behavioral neuroscience. vol 12. 2020-10-01. PMID:29434542. |
previous findings from this laboratory demonstrate: (1) that different classes of addictive drugs require intact norepinephrine (ne) transmission in the medial pre frontal cortex (mpfc) to promote conditioned place preference and to increase dopamine (da) tone in the nucleus accumbens shell (nac shell); (2) that only food-restricted mice require intact ne transmission in the mpfc to develop conditioned preference for a context associated with milk chocolate; and (3) that food-restricted mice show a significantly larger increase of mpfc ne outflow then free fed mice when experiencing the palatable food for the first time. |
2020-10-01 |
2023-08-13 |
mouse |
| Tom Macpherson, Takatoshi Hikid. Nucleus Accumbens Dopamine D1-Receptor-Expressing Neurons Control the Acquisition of Sign-Tracking to Conditioned Cues in Mice. Frontiers in neuroscience. vol 12. 2020-10-01. PMID:29977188. |
neurotransmission blocking of nac d1-msns inhibited the acquisition of sign-tracking responses when the initial conditioned response for each conditioned stimulus presentation was examined, confirming our initial hypothesis. |
2020-10-01 |
2023-08-13 |
mouse |
| Tom Macpherson, Takatoshi Hikid. Nucleus Accumbens Dopamine D1-Receptor-Expressing Neurons Control the Acquisition of Sign-Tracking to Conditioned Cues in Mice. Frontiers in neuroscience. vol 12. 2020-10-01. PMID:29977188. |
these findings suggest that activity in nac d1-msns contributes to the attribution of incentive salience to conditioned stimuli. |
2020-10-01 |
2023-08-13 |
mouse |
| Valentina Bassareo, Flavia Cucca, Roberto Frau, Gaetano Di Chiar. Changes in Dopamine Transmission in the Nucleus Accumbens Shell and Core during Ethanol and Sucrose Self-Administration. Frontiers in behavioral neuroscience. vol 11. 2020-09-30. PMID:28507512. |
these observations provide unequivocal evidence that oral sa of 10% ethanol increases dialysate da in the nac, and also suggest that stimuli conditioned to ethanol exposure contribute to the increase of dialysate da observed in the nac following ethanol sa. |
2020-09-30 |
2023-08-13 |
rat |
| Javier A Muñiz, José P Prieto, Betina González, Máximo H Sosa, Jean L Cadet, Cecilia Scorza, Francisco J Urbano, Verónica Bisagn. Cocaine and Caffeine Effects on the Conditioned Place Preference Test: Concomitant Changes on Early Genes within the Mouse Prefrontal Cortex and Nucleus Accumbens. Frontiers in behavioral neuroscience. vol 11. 2020-09-30. PMID:29093669. |
the goal of the present study was thus to determine caffeine and cocaine combined effects on the conditioned place preference (cpp) test and to determine potential differential mrna expression in the nucleus accumbens (nac) and medial prefrontal cortex (mpfc) of immediate-early genes (iegs) as well as dopamine and adenosine receptor subunits. |
2020-09-30 |
2023-08-13 |
mouse |
| Chelsea N Brown, Elissa K Fultz, Sami Ferdousian, Sarina Rogers, Elijah Lustig, Ariana Page, John R Shahin, Daniel M Flaherty, Georg Von Jonquieres, Camron D Bryant, Tod E Kippin, Karen K Szumlinsk. Transgenic Analyses of Homer2 Function Within Nucleus Accumbens Subregions in the Regulation of Methamphetamine Reward and Reinforcement in Mice. Frontiers in psychiatry. vol 11. 2020-09-28. PMID:32116834. |
this report extends our earlier work by interrogating the functional relevance of homer2 within the nac core for the conditioned rewarding and reinforcing properties of ma. |
2020-09-28 |
2023-08-13 |
mouse |
| Chelsea N Brown, Elissa K Fultz, Sami Ferdousian, Sarina Rogers, Elijah Lustig, Ariana Page, John R Shahin, Daniel M Flaherty, Georg Von Jonquieres, Camron D Bryant, Tod E Kippin, Karen K Szumlinsk. Transgenic Analyses of Homer2 Function Within Nucleus Accumbens Subregions in the Regulation of Methamphetamine Reward and Reinforcement in Mice. Frontiers in psychiatry. vol 11. 2020-09-28. PMID:32116834. |
c57bl/6j mice with a virus-mediated knockdown of homer2b expression within the nac core were first tested for the development and expression of a ma-induced conditioned place-preference/cpp (four pairings of 2 mg/kg ma) and then were trained to self-administer oral ma under operant-conditioning procedures (5-80 mg/l). |
2020-09-28 |
2023-08-13 |
mouse |
| David P Dunn, Joshua M R Bastacky, Christopher C Gray, Shayan Abtahi, Paul J Curri. Role of mesolimbic ghrelin in the acquisition of cocaine reward. Neuroscience letters. vol 709. 2020-09-24. PMID:31278962. |
the present study examined the ability of ghrelin administration into either the ventral tegmental area (vta) or nucleus accumbens (nac) to potentiate cocaine-induced conditioned place preference (cpp). |
2020-09-24 |
2023-08-13 |
rat |
| In-Jee You, Sa-Ik Hong, Shi-Xun Ma, Thi-Lien Nguyen, Seung-Hwan Kwon, Seok-Yong Lee, Choon-Gon Jan. Transient receptor potential vanilloid 1 mediates cocaine reinstatement via the D1 dopamine receptor in the nucleus accumbens. Journal of psychopharmacology (Oxford, England). vol 33. issue 12. 2020-08-14. PMID:31432769. |
we investigated the mechanism of trpv1 in nac on cocaine reinstatement using the conditioned place preference (cpp) test in mice. |
2020-08-14 |
2023-08-13 |
mouse |
| Yiheng Tu, Yanzhi Bi, Libo Zhang, Hua Wei, Li H. Mesocorticolimbic Pathways Encode Cue-Based Expectancy Effects on Pain. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 40. issue 2. 2020-07-13. PMID:31694965. |
at the between-subject level, multivariate pattern analyses demonstrated that gray matter volumes in the vta, nac, and racc were able to predict the magnitudes of conditioned pain responses associated with positive and/or negative expectations across subjects. |
2020-07-13 |
2023-08-13 |
human |
| Dan P Covey, Joseph F Chee. Accumbal Dopamine Release Tracks the Expectation of Dopamine Neuron-Mediated Reinforcement. Cell reports. vol 27. issue 2. 2020-06-22. PMID:30970251. |
we find that cues predicting access to da neuron self-stimulation elicit conditioned responding and nac da release. |
2020-06-22 |
2023-08-13 |
Not clear |
| Michael A Benneyworth, Matthew C Hearing, Anders J Asp, Aric Madayag, Anna E Ingebretson, Clare E Schmidt, Keelia A Silvis, Erin B Larson, Stephanie R Ebner, Mark J Thoma. Synaptic Depotentiation and mGluR5 Activity in the Nucleus Accumbens Drive Cocaine-Primed Reinstatement of Place Preference. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 39. issue 24. 2020-06-12. PMID:30948476. |
the present studies investigated a causal link between cocaine-induced reinstatement of conditioned place preference and rapid reductions of cocaine-dependent increases in nac shell synaptic strength in male mice. |
2020-06-12 |
2023-08-13 |
mouse |
| Daniel Vallöf, Aimilia Lydia Kalafateli, Elisabet Jerlha. Brain region specific glucagon-like peptide-1 receptors regulate alcohol-induced behaviors in rodents. Psychoneuroendocrinology. vol 103. 2020-04-23. PMID:30771711. |
we therefore evaluated the effects of bilateral infusion of the glp-1r agonist exendin-4 (ex4) into nac shell, anterior (avta), posterior (pvta) or ldtg on the acute alcohol-induced locomotor stimulation and memory of alcohol reward in the conditioned place preference (cpp) model in mice, as well as on alcohol intake in rats consuming high amounts of alcohol for 12 weeks. |
2020-04-23 |
2023-08-13 |
mouse |
| Yanaira Alonso-Caraballo, Carrie R Ferrari. Effects of the estrous cycle and ovarian hormones on cue-triggered motivation and intrinsic excitability of medium spiny neurons in the Nucleus Accumbens core of female rats. Hormones and behavior. vol 116. 2020-04-14. PMID:31454509. |
therefore, we examined basal differences in intrinsic nac excitability of obesity-prone vs. obesity-resistant females and determined how conditioned approach (a measure of cue-triggered motivation), food intake, and motivation for food vary with the cycle in naturally cycling female obesity-prone, obesity-resistant, and outbred sprague-dawley rats. |
2020-04-14 |
2023-08-13 |
rat |
| Yanaira Alonso-Caraballo, Carrie R Ferrari. Effects of the estrous cycle and ovarian hormones on cue-triggered motivation and intrinsic excitability of medium spiny neurons in the Nucleus Accumbens core of female rats. Hormones and behavior. vol 116. 2020-04-14. PMID:31454509. |
we found that intrinsic excitability of nac msns and conditioned approach are enhanced in female obesity-prone vs. obesity-resistant rats. |
2020-04-14 |
2023-08-13 |
rat |