Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
M T Bard. Neuropharmacological mechanisms of drug reward: beyond dopamine in the nucleus accumbens. Critical reviews in neurobiology. vol 12. issue 1-2. 1998-02-24. PMID:9444481. |
neuropharmacological mechanisms of drug reward: beyond dopamine in the nucleus accumbens. |
1998-02-24 |
2023-08-12 |
Not clear |
M T Bard. Neuropharmacological mechanisms of drug reward: beyond dopamine in the nucleus accumbens. Critical reviews in neurobiology. vol 12. issue 1-2. 1998-02-24. PMID:9444481. |
gabaergic circuitry descending from the nucleus accumbens to the pedunculopontine tegmental nucleus via the ventral pallidum appears to be especially important in directing the behavioral sequelae associated with reward produced by various drugs of abuse. |
1998-02-24 |
2023-08-12 |
Not clear |
M T Bard. Neuropharmacological mechanisms of drug reward: beyond dopamine in the nucleus accumbens. Critical reviews in neurobiology. vol 12. issue 1-2. 1998-02-24. PMID:9444481. |
with amphetamine and cocaine, initiation of reward is controlled within the nucleus accumbens and prefrontal cortex, respectively. |
1998-02-24 |
2023-08-12 |
Not clear |
S Ikemoto, B S Glazier, J M Murphy, W J McBrid. Role of dopamine D1 and D2 receptors in the nucleus accumbens in mediating reward. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 17. issue 21. 1997-11-20. PMID:9334429. |
role of dopamine d1 and d2 receptors in the nucleus accumbens in mediating reward. |
1997-11-20 |
2023-08-12 |
rat |
S Ikemoto, B S Glazier, J M Murphy, W J McBrid. Role of dopamine D1 and D2 receptors in the nucleus accumbens in mediating reward. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 17. issue 21. 1997-11-20. PMID:9334429. |
the present results suggest that concurrent activation of d1- and d2-type receptors in the shell of the acb had a cooperative effect on da-mediated reward processes. |
1997-11-20 |
2023-08-12 |
rat |
W Gong, J B Justice, D Neil. Dissociation of locomotor and conditioned place preference responses following manipulation of GABA-A and AMPA receptors in ventral pallidum. Progress in neuro-psychopharmacology & biological psychiatry. vol 21. issue 5. 1997-10-29. PMID:9278955. |
in addition, it was argued that the gabaergic projection from nucleus accumbens to ventral pallidum may not be involved in the processing of reward initiated from dopaminergic activation in nucleus accumbens. |
1997-10-29 |
2023-08-12 |
Not clear |
B Setlo. The nucleus accumbens and learning and memory. Journal of neuroscience research. vol 49. issue 5. 1997-10-23. PMID:9302072. |
recent research on the nucleus accumbens (na) indicates that this brain region is involved in learning and memory processes in a way that is separable from its other well-known roles in behavior, such as motivation, reward, and locomotor activity. |
1997-10-23 |
2023-08-12 |
Not clear |
P Le Grevès, W Huang, P Johansson, M Thörnwall, Q Zhou, F Nyber. Effects of an anabolic-androgenic steroid on the regulation of the NMDA receptor NR1, NR2A and NR2B subunit mRNAs in brain regions of the male rat. Neuroscience letters. vol 226. issue 1. 1997-07-21. PMID:9153642. |
the downregulation of the mrna for the nr1 receptor subunit in nucleus accumbens may relate to a mechanism involved in the recently suggested aas-induced stimulation of the brain reward system. |
1997-07-21 |
2023-08-12 |
rat |
J D Salamone, M S Cousins, B J Snyde. Behavioral functions of nucleus accumbens dopamine: empirical and conceptual problems with the anhedonia hypothesis. Neuroscience and biobehavioral reviews. vol 21. issue 3. 1997-07-21. PMID:9168269. |
nucleus accumbens (da) has been implicated in a number of different behavioral functions, but most commonly it is said to be involved in "reward" or "reinforcement". |
1997-07-21 |
2023-08-12 |
Not clear |
J D Salamone, M S Cousins, B J Snyde. Behavioral functions of nucleus accumbens dopamine: empirical and conceptual problems with the anhedonia hypothesis. Neuroscience and biobehavioral reviews. vol 21. issue 3. 1997-07-21. PMID:9168269. |
according to this model, the da innervation of the nucleus accumbens is conceived of as a crucial link in the "reward system", which evolved to mediate the reinforcing effects of natural stimuli such as food. |
1997-07-21 |
2023-08-12 |
Not clear |
C L Duvauchelle, S M Fleming, C Kornetsk. Involvement of delta- and mu-opioid receptors in the potentiation of brain-stimulation reward. European journal of pharmacology. vol 316. issue 2-3. 1997-06-12. PMID:8982679. |
these data demonstrate nucleus accumbens activation of delta- and mu-opioid receptors and ventral tegmental area brain-stimulation reward share common brain substrates. |
1997-06-12 |
2023-08-12 |
Not clear |
G Panagis, G G Nomikos, E Miliaressis, K Chergui, A Kastellakis, T H Svensson, C Spyrak. Ventral pallidum self-stimulation induces stimulus dependent increase in c-fos expression in reward-related brain regions. Neuroscience. vol 77. issue 1. 1997-05-02. PMID:9044385. |
fos-like immunoreactivity was found to increase as a function of pulse frequency in several brain regions known to be involved in drug and/or brain stimulation reward (medial prefrontal cortex, lateral septum, nucleus accumbens; lateral hypothalamus and ventral tegmental area), whereas it was not affected in structures devoid of such involvement (substantia nigra reticulata and dorsolateral striatum). |
1997-05-02 |
2023-08-12 |
human |
S R White, T Obradovic, K M Imel, M J Wheato. The effects of methylenedioxymethamphetamine (MDMA, "Ecstasy") on monoaminergic neurotransmission in the central nervous system. Progress in neurobiology. vol 49. issue 5. 1997-02-19. PMID:8895996. |
experiments in awake, behaving laboratory animals have demonstrated that single injections of mdma increase extracellular levels of the neurotransmitters dopamine (da) and serotonin (5ht) in the nucleus accumbens and in several other brain regions that are important for reward. |
1997-02-19 |
2023-08-12 |
Not clear |
A Dalia, L J Wallac. Amphetamine induction of c-fos in the nucleus accumbens is not inhibited by glutamate antagonists. Brain research. vol 694. issue 1-2. 1996-12-27. PMID:8974658. |
therefore, it was determined if low doses of amphetamine capable of eliciting reward and sensitization increase levels of c-fos protein in the nucleus accumbens. |
1996-12-27 |
2023-08-12 |
rat |
P J Fletche. Injection of 5-HT into the nucleus accumbens reduces the effects of d-amphetamine on responding for conditioned reward. Psychopharmacology. vol 126. issue 1. 1996-12-23. PMID:8853218. |
injection of 5-ht into the nucleus accumbens reduces the effects of d-amphetamine on responding for conditioned reward. |
1996-12-23 |
2023-08-12 |
rat |
P J Fletche. Injection of 5-HT into the nucleus accumbens reduces the effects of d-amphetamine on responding for conditioned reward. Psychopharmacology. vol 126. issue 1. 1996-12-23. PMID:8853218. |
injection of d-amphetamine into the nucleus accumbens potentiates responding for stimuli paired with a primary reward. |
1996-12-23 |
2023-08-12 |
rat |
P I Johnson, M A Parente, J R Stella. NMDA-induced lesions of the nucleus accumbens or the ventral pallidum increase the rewarding efficacy of food to deprived rats. Brain research. vol 722. issue 1-2. 1996-12-18. PMID:8813355. |
the role of the nucleus accumbens (nac) and ventral pallidum (vp) in food reward modulation was investigated using heyman's [24] curve fitting approach in food deprived rats. |
1996-12-18 |
2023-08-12 |
rat |
P Gorwood, M P Martres, J Adès, P Sokoloff, E P Noble, T Geijer, K Blum, J Neiman, E Jönsson, J Feingol. Lack of association between alcohol-dependence and D3 dopamine receptor gene in three independent samples. American journal of medical genetics. vol 60. issue 6. 1996-12-05. PMID:8825889. |
another receptor, the d3 dopamine receptor (drd3), may be of additional interest since it is specifically located in the limbic area, and in particular in the nucleus accumbens which plays a significant role in the reward process of addiction behavior. |
1996-12-05 |
2023-08-12 |
Not clear |
A E Kelley, E P Bless, C J Swanso. Investigation of the effects of opiate antagonists infused into the nucleus accumbens on feeding and sucrose drinking in rats. The Journal of pharmacology and experimental therapeutics. vol 278. issue 3. 1996-11-05. PMID:8819538. |
the putative contributions of mu and delta receptors within the nucleus accumbens to modulation of food reward are discussed. |
1996-11-05 |
2023-08-12 |
rat |
V J Brown, E M Bowma. Discriminative cues indicating reward magnitude continue to determine reaction time of rats following lesions of the nucleus accumbens. The European journal of neuroscience. vol 7. issue 12. 1996-10-22. PMID:8845953. |
discriminative cues indicating reward magnitude continue to determine reaction time of rats following lesions of the nucleus accumbens. |
1996-10-22 |
2023-08-12 |
rat |