| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A N Talalaenko, I K Boreĭsh. [Pharmacological analysis of the serotonin- and glutamatergic mechanisms in the suppressive effect of neuroleptics on the pedal self-stimulation of the ventral tectum of the midbrain]. Farmakologiia i toksikologiia. vol 49. issue 3. 1986-08-15. PMID:2873054. |
the glutamatergic mechanisms of neostriatum and nucleus accumbens septi play a minor role in attenuation of tegmental self-stimulation with droperidol, fluphenazine, trifluoperazine and clozapine but these mechanisms seem to be responsible for the suppression of "reward" phenomenon with haloperidol, thioridazine and aminazine. |
1986-08-15 |
2023-08-11 |
Not clear |
| F J Vaccarino, F E Bloom, G F Koo. Blockade of nucleus accumbens opiate receptors attenuates intravenous heroin reward in the rat. Psychopharmacology. vol 86. issue 1-2. 1985-09-25. PMID:2991967. |
blockade of nucleus accumbens opiate receptors attenuates intravenous heroin reward in the rat. |
1985-09-25 |
2023-08-11 |
rat |
| F J Vaccarino, G F Koo. Microinjections of nanogram amounts of sulfated cholecystokinin octapeptide into the rat nucleus accumbens attenuates brain stimulation reward. Neuroscience letters. vol 52. issue 1-2. 1985-04-19. PMID:6098878. |
microinjections of nanogram amounts of sulfated cholecystokinin octapeptide into the rat nucleus accumbens attenuates brain stimulation reward. |
1985-04-19 |
2023-08-12 |
rat |
| B G Hoebel, A P Monaco, L Hernandez, E F Aulisi, B G Stanley, L Lenar. Self-injection of amphetamine directly into the brain. Psychopharmacology. vol 81. issue 2. 1983-12-20. PMID:6415748. |
this localization of 'amphetamine reward' suggests that the nucleus accumbens contains a synaptic mechanism underlying amphetamine abuse and, perhaps, also natural reinforcement of behavior. |
1983-12-20 |
2023-08-12 |
rat |
| O F Jenkins, D M Atrens, D M Jackso. Self-stimulation of the nucleus accumbens and some comparisons with hypothalamic self-stimulation. Pharmacology, biochemistry, and behavior. vol 18. issue 4. 1983-08-11. PMID:6867063. |
the results show that acb self-stimulation is a very different phenomenon to hyp self-stimulation, and suggest that, in addition to reward and aversion, acb self-stimulation may involve a stereotyped ritual controlled partly by adaptation and conditioning. |
1983-08-11 |
2023-08-12 |
rat |
| T F Seeger, E L Gardne. Enhancement of self-stimulation behavior in rats and monkeys after chronic neuroleptic treatment: evidence for mesolimbic supersensitivity. Brain research. vol 175. issue 1. 1979-12-20. PMID:114275. |
in addition, four rhesus monkeys with electrodes in the nucleus accumbens (one of the terminal projection areas of the a10 mesolimbic dopamine system) were given a three week treatment with haloperidol, after which all animals showed a significant, long-lasting decrease in self-stimulation threshold, as measured by a rate-independent reward paradigm. |
1979-12-20 |
2023-08-11 |
rat |
| G J Mogenson, M Takigawa, A Robertson, M W. Self-stimulation of the nucleus accumbens and ventral tegmental area of Tsai attenuated by microinjections of spiroperidol into the nucleus accumbens. Brain research. vol 171. issue 2. 1979-10-17. PMID:572734. |
these observations provide additional evidence implicating dopaminergic neurons in brain-stimulation reward and suggest that dopaminergic neurons contribute to self-stimulation of the nucleus accumbens but not the prefrontal cortex. |
1979-10-17 |
2023-08-11 |
Not clear |