| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| N M White, M G Packard, N Hiro. Place conditioning with dopamine D1 and D2 agonists injected peripherally or into nucleus accumbens. Psychopharmacology. vol 103. issue 2. 1991-06-12. PMID:1674160. |
these results suggest that activation of either d1 or d2 receptors in the nucleus accumbens can produce reward, and that d1 receptors (and possibly also d2 receptors) located elsewhere in the brain or in the periphery may mediate aversive effects. |
1991-06-12 |
2023-08-11 |
rat |
| A E Kelley, J M Delf. Dopamine and conditioned reinforcement. II. Contrasting effects of amphetamine microinjection into the nucleus accumbens with peptide microinjection into the ventral tegmental area. Psychopharmacology. vol 103. issue 2. 1991-06-12. PMID:1709289. |
in contrast, amphetamine (0, 0.2, 2.0, 20 micrograms) injected into the nucleus accumbens markedly enhanced responding for conditioned reward. |
1991-06-12 |
2023-08-11 |
rat |
| A E Kelley, J M Delf. Dopamine and conditioned reinforcement. I. Differential effects of amphetamine microinjections into striatal subregions. Psychopharmacology. vol 103. issue 2. 1991-06-12. PMID:2027920. |
it has been shown that psychostimulants potentiate responding for conditioned reward and there is evidence that the nucleus accumbens is involved in this effect. |
1991-06-12 |
2023-08-11 |
rat |
| J P Chen, W Paredes, J Li, D Smith, J Lowinson, E L Gardne. Delta 9-tetrahydrocannabinol produces naloxone-blockable enhancement of presynaptic basal dopamine efflux in nucleus accumbens of conscious, freely-moving rats as measured by intracerebral microdialysis. Psychopharmacology. vol 102. issue 2. 1991-02-26. PMID:2177204. |
delta 9-thc, at low doses (0.5-1.0 mg/kg), which significantly enhance brain stimulation reward (intracranial self-stimulation), significantly increased da efflux in nucleus accumbens. |
1991-02-26 |
2023-08-11 |
rat |
| M H Joseph, H Hodge. Lever pressing for food reward and changes in dopamine turnover and uric acid in rat caudate and nucleus accumbens studied chronically by in vivo voltammetry. Journal of neuroscience methods. vol 34. issue 1-3. 1991-01-31. PMID:2259235. |
lever pressing for food reward and changes in dopamine turnover and uric acid in rat caudate and nucleus accumbens studied chronically by in vivo voltammetry. |
1991-01-31 |
2023-08-11 |
rat |
| G H Jones, C A Marsden, T W Robbin. Increased sensitivity to amphetamine and reward-related stimuli following social isolation in rats: possible disruption of dopamine-dependent mechanisms of the nucleus accumbens. Psychopharmacology. vol 102. issue 3. 1991-01-17. PMID:2251333. |
in experiment 2, hungry rats were trained to associate a compound light/noise stimulus with sucrose reward and were then implanted with guide cannulae in the nucleus accumbens. |
1991-01-17 |
2023-08-11 |
rat |
| N Hiroi, N M Whit. The reserpine-sensitive dopamine pool mediates (+)-amphetamine-conditioned reward in the place preference paradigm. Brain research. vol 510. issue 1. 1990-05-21. PMID:2322845. |
these data show that (+)-amphetamine-conditioned reward, expressed as a conditioned place preference, is mediated by dopamine release in the nucleus accumbens. |
1990-05-21 |
2023-08-11 |
Not clear |
| K R Evans, F J Vaccarin. Amphetamine- and morphine-induced feeding: evidence for involvement of reward mechanisms. Neuroscience and biobehavioral reviews. vol 14. issue 1. 1990-05-21. PMID:2325945. |
in addition, the importance of the nucleus accumbens (acb), a critical structure for amp and mor reward, in these effects was determined. |
1990-05-21 |
2023-08-11 |
Not clear |
| K R Evans, F J Vaccarin. Amphetamine- and morphine-induced feeding: evidence for involvement of reward mechanisms. Neuroscience and biobehavioral reviews. vol 14. issue 1. 1990-05-21. PMID:2325945. |
the relevance of the present findings for our understanding of which elements of food and feeding behavior are coupled with acb reward signals is also discussed. |
1990-05-21 |
2023-08-11 |
Not clear |
| J E Kelsey, W A Carlezon, W A Fall. Lesions of the nucleus accumbens in rats reduce opiate reward but do not alter context-specific opiate tolerance. Behavioral neuroscience. vol 103. issue 6. 1990-03-08. PMID:2558677. |
lesions of the nucleus accumbens in rats reduce opiate reward but do not alter context-specific opiate tolerance. |
1990-03-08 |
2023-08-11 |
rat |
| R A Wis. Opiate reward: sites and substrates. Neuroscience and biobehavioral reviews. vol 13. issue 2-3. 1989-12-12. PMID:2573023. |
opioid injections into the nucleus accumbens (nas) also facilitate brain stimulation reward and serve as rewards in their own right, though these actions have not yet been localized by identification of negative sites in surrounding regions. |
1989-12-12 |
2023-08-11 |
Not clear |
| J R Stellar, D Corbet. Regional neuroleptic microinjections indicate a role for nucleus accumbens in lateral hypothalamic self-stimulation reward. Brain research. vol 477. issue 1-2. 1989-05-19. PMID:2495150. |
regional neuroleptic microinjections indicate a role for nucleus accumbens in lateral hypothalamic self-stimulation reward. |
1989-05-19 |
2023-08-11 |
human |
| R A Wise, P P Rompr. Brain dopamine and reward. Annual review of psychology. vol 40. 1989-04-24. PMID:2648975. |
in the cases where pharmacological challenge has been examined, only nucleus accumbens and frontal cortex have been found to have dopamine-independent reward sites. |
1989-04-24 |
2023-08-11 |
Not clear |
| R A Wise, P P Rompr. Brain dopamine and reward. Annual review of psychology. vol 40. 1989-04-24. PMID:2648975. |
it is not consistent with the dopamine hypothesis that dopamine-independent reward sites should exist in these areas, since any reward signals carried to nucleus accumbens or frontal cortex by dopamine fibers would-unless we are to believe that reward "happens" at these sites-have to be carried to the next stage of the circuit by nondopaminergic fibers (there are no dopaminergic cell bodies in any of the dopamine terminal areas). |
1989-04-24 |
2023-08-11 |
Not clear |
| F J Vaccarino, A L Vaccarin. Antagonism of cholecystokinin function in the rostral and caudal nucleus accumbens: differential effects on brain stimulation reward. Neuroscience letters. vol 97. issue 1-2. 1989-04-06. PMID:2918999. |
antagonism of cholecystokinin function in the rostral and caudal nucleus accumbens: differential effects on brain stimulation reward. |
1989-04-06 |
2023-08-11 |
Not clear |
| L M Colle, R A Wis. Effects of nucleus accumbens amphetamine on lateral hypothalamic brain stimulation reward. Brain research. vol 459. issue 2. 1988-11-28. PMID:3179710. |
effects of nucleus accumbens amphetamine on lateral hypothalamic brain stimulation reward. |
1988-11-28 |
2023-08-11 |
Not clear |
| L M Colle, R A Wis. Effects of nucleus accumbens amphetamine on lateral hypothalamic brain stimulation reward. Brain research. vol 459. issue 2. 1988-11-28. PMID:3179710. |
these data suggest that nucleus accumbens is a site of amphetamine's reward-enhancing and threshold-lowering effects on brain stimulation reward. |
1988-11-28 |
2023-08-11 |
Not clear |
| B Nurse, V A Russell, J J Taljaar. Characterization of the effects of serotonin on the release of [3H]dopamine from rat nucleus accumbens and striatal slices. Neurochemical research. vol 13. issue 5. 1988-09-22. PMID:3165497. |
the present results do not preclude the possibility that serotonin may affect the mesolimbic reward system at a site which is post-synaptic to dopaminergic terminals in the nucleus accumbens. |
1988-09-22 |
2023-08-11 |
rat |
| L Hernandez, B G Hoebe. Food reward and cocaine increase extracellular dopamine in the nucleus accumbens as measured by microdialysis. Life sciences. vol 42. issue 18. 1988-06-03. PMID:3362036. |
food reward and cocaine increase extracellular dopamine in the nucleus accumbens as measured by microdialysis. |
1988-06-03 |
2023-08-11 |
rat |
| J M Murphy, W J McBride, L Lumeng, T K L. Contents of monoamines in forebrain regions of alcohol-preferring (P) and -nonpreferring (NP) lines of rats. Pharmacology, biochemistry, and behavior. vol 26. issue 2. 1987-06-02. PMID:2437596. |
this observation may indicate that p rats have a specific deficiency in the dopaminergic projections from the ventral tegmental area to the nucleus accumbens and, since the accumbens is an important structure in brain reward circuitry, it might also be an important determinant of the excessive volitional intake of alcohol by p rats. |
1987-06-02 |
2023-08-11 |
rat |