| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Nazanin Kahvandi, Zahra Ebrahimi, Maryam Sharifi, Seyed Asaad Karimi, Siamak Shahidi, Iraj Salehi, Rasool Haddadi, Abdolrahman Sarih. S-3,4-DCPG, a potent orthosteric agonist for the mGlu8 receptor, facilitates extinction and inhibits the reinstatement of morphine-induced conditioned place preference in male rats. Pharmacology, biochemistry, and behavior. 2024-04-23. PMID:38653345. |
this effect may be associated with the modulation of glutamate engagement within the nac and the plasticity of reward pathways at the synaptic level. |
2024-04-23 |
2024-04-26 |
rat |
| Shelby Travaglianti, Ahmed Alotaibi, Woonyen Wong, Magid Abou-Gharbia, Wayne Childers, Youssef Sar. Effects of novel GLT-1 modulator, MC-100093, on neuroinflammatory and neurotrophic biomarkers in mesocorticolimbic brain regions of male alcohol preferring rats exposed chronically to ethanol. Brain research bulletin. 2024-04-03. PMID:38570076. |
chronic ethanol consumption can lead to increased extracellular glutamate concentrations in key reward brain regions, such as medial prefrontal cortex (mpfc) and nucleus accumbens (nac), and consequently leading to oxidative stress and neuroinflammation. |
2024-04-03 |
2024-04-06 |
rat |
| Cassandra Avila, Martin Sarte. Cortico-striatal action control inherent of opponent cognitive-motivational styles. bioRxiv : the preprint server for biology. 2024-04-01. PMID:38559086. |
in contrast, in sts, glutamate release from dms glutamatergic terminals is regulated by other striatal circuitry, preferably mediating cued suppression of action and reward tracking. |
2024-04-01 |
2024-04-04 |
rat |
| Tolulope Adeyelu, Tashonda Vaughn, Olalekan M Ogundel. VTA excitatory neurons impact reward-driven behavior by modulating infralimbic cortical firing. Neuroscience. 2024-03-21. PMID:38513762. |
pairing vta glutamate inhibition with reward acquisition events reduced the weight of reward-target association expressed as a lower affinity for previously rewarded targets. |
2024-03-21 |
2024-03-24 |
mouse |
| Tolulope Adeyelu, Tashonda Vaughn, Olalekan M Ogundel. VTA excitatory neurons impact reward-driven behavior by modulating infralimbic cortical firing. Neuroscience. 2024-03-21. PMID:38513762. |
together, we conclude that vta glutamate neurons are likely involved in establishing il inhibition states that encode reward acquisition, and subsequent reward-target association when a reward is omitted. |
2024-03-21 |
2024-03-24 |
mouse |
| Nicholas Pintori, Alessandro Piva, Francesca Mottarlini, Fernando Castillo Díaz, Coralie Maggi, Lucia Caffino, Fabio Fumagalli, Cristiano Chiamuler. Brief exposure to enriched environment rapidly shapes the glutamate synapses in the rat brain: A metaplastic fingerprint. The European journal of neuroscience. 2024-02-20. PMID:38378276. |
adult male sprague-dawley rats were exposed to ee for 22 h and the expression of critical elements of the glutamate synapse was measured 2 h after the end of ee in the medial prefrontal cortex (mpfc), nucleus accumbens (nac) and hippocampus (hipp) brain areas, which are critical for reward and memory. |
2024-02-20 |
2024-02-23 |
rat |
| Ryunosuke Amo, Naoshige Uchida, Mitsuko Watabe-Uchid. Glutamate inputs send prediction error of reward, but not negative value of aversive stimuli, to dopamine neurons. Neuron. 2024-01-26. PMID:38278147. |
glutamate inputs send prediction error of reward, but not negative value of aversive stimuli, to dopamine neurons. |
2024-01-26 |
2024-01-29 |
mouse |
| Ryunosuke Amo, Naoshige Uchida, Mitsuko Watabe-Uchid. Glutamate inputs send prediction error of reward, but not negative value of aversive stimuli, to dopamine neurons. Neuron. 2024-01-26. PMID:38278147. |
we found that glutamate inputs exhibit virtually all of the characteristics of rpe rather than conveying a specific component of rpe computation, such as reward or expectation. |
2024-01-26 |
2024-01-29 |
mouse |
| Ryunosuke Amo, Naoshige Uchida, Mitsuko Watabe-Uchid. Glutamate inputs send prediction error of reward, but not negative value of aversive stimuli, to dopamine neurons. Neuron. 2024-01-26. PMID:38278147. |
notably, whereas glutamate inputs were transiently inhibited by reward omission, they were excited by aversive stimuli. |
2024-01-26 |
2024-01-29 |
mouse |
| Shelley M Warlow, Sarthak M Singhal, Nick G Hollon, Lauren Faget, Dina S Dowlat, Vivien Zell, Avery C Hunker, Larry S Zweifel, Thomas S Hnask. Mesoaccumbal glutamate neurons drive reward via glutamate release but aversion via dopamine co-release. Neuron. 2023-12-12. PMID:38086374. |
mesoaccumbal glutamate neurons drive reward via glutamate release but aversion via dopamine co-release. |
2023-12-12 |
2023-12-17 |
mouse |
| Ryunosuke Amo, Naoshige Uchida, Mitsuko Watabe-Uchid. Glutamate inputs send prediction error of reward but not negative value of aversive stimuli to dopamine neurons. bioRxiv : the preprint server for biology. 2023-11-21. PMID:37986868. |
glutamate inputs send prediction error of reward but not negative value of aversive stimuli to dopamine neurons. |
2023-11-21 |
2023-11-29 |
Not clear |
| Ryunosuke Amo, Naoshige Uchida, Mitsuko Watabe-Uchid. Glutamate inputs send prediction error of reward but not negative value of aversive stimuli to dopamine neurons. bioRxiv : the preprint server for biology. 2023-11-21. PMID:37986868. |
we found that glutamate inputs exhibit virtually all of the characteristics of rpe, rather than conveying a specific component of rpe computation such as reward or expectation. |
2023-11-21 |
2023-11-29 |
Not clear |
| Ryunosuke Amo, Naoshige Uchida, Mitsuko Watabe-Uchid. Glutamate inputs send prediction error of reward but not negative value of aversive stimuli to dopamine neurons. bioRxiv : the preprint server for biology. 2023-11-21. PMID:37986868. |
notably, while glutamate inputs were transiently inhibited by reward omission, they were excited by aversive stimuli. |
2023-11-21 |
2023-11-29 |
Not clear |
| b' Giovanni Hernandez, Willemieke M Kouwenhoven, Emmanuelle Poirier, Karim Lebied, Daniel L\\xc3\\xa9vesque, Pierre-Paul Rompr\\xc3\\xa. Dorsal raphe stimulation relays a reward signal to the ventral tegmental area via GluN2C NMDA receptors. PloS one. vol 18. issue 11. 2023-11-06. PMID:37930965.' |
glutamate relays a reward signal from the dorsal raphe (dr) to the ventral tegmental area (vta). |
2023-11-06 |
2023-11-08 |
Not clear |
| Kristen Kim, Marina R Picciott. Nicotine addiction: More than just dopamine. Current opinion in neurobiology. vol 83. 2023-10-13. PMID:37832393. |
in particular, although dopaminergic mechanisms are necessary for nicotine-dependent reward and drug-seeking, novel glutamate and gaba signaling mechanisms in the mesolimbic system have been identified for their contributions to reward-related behaviors. |
2023-10-13 |
2023-10-15 |
Not clear |
| Cristina Ibáñez, Tirso Acuña, María Elena Quintanilla, Diliana Pérez-Reytor, Paola Morales, Eduardo Karahania. Fenofibrate Decreases Ethanol-Induced Neuroinflammation and Oxidative Stress and Reduces Alcohol Relapse in Rats by a PPAR-α-Dependent Mechanism. Antioxidants (Basel, Switzerland). vol 12. issue 9. 2023-09-28. PMID:37760061. |
this inflammation boosts glutamate, prompting dopamine release in reward centers, driving prolonged drinking and relapse. |
2023-09-28 |
2023-10-07 |
rat |
| Lauren Faget, Lucie Oriol, Wen-Chun Lee, Cody Sargent, Dhakshin Ramanathan, Thomas S Hnask. Ventral pallidum GABA and glutamate neurons drive approach and avoidance through distinct modulation of VTA cell types. bioRxiv : the preprint server for biology. 2023-07-28. PMID:37502884. |
here, we found that both vp gaba and glut neurons were activated during approach to reward or delivery of an aversive stimulus. |
2023-07-28 |
2023-08-14 |
human |
| Yiting Hu, Fang Dong, Ting Xue, Mi Zhou, Ruoyan Huang, Feng Sui, Qiang Guo, Wenbao Hou, Wenlong Cai, Kai Yuan, Hongde Wang, Dahua Y. Glutamate levels in the ventromedial prefrontal cortex and resting-state functional connectivity within reward circuits in alcohol-dependent patients. Addiction biology. vol 28. issue 4. 2023-04-05. PMID:37016753. |
glutamate levels in the ventromedial prefrontal cortex and resting-state functional connectivity within reward circuits in alcohol-dependent patients. |
2023-04-05 |
2023-08-14 |
Not clear |
| Yiting Hu, Fang Dong, Ting Xue, Mi Zhou, Ruoyan Huang, Feng Sui, Qiang Guo, Wenbao Hou, Wenlong Cai, Kai Yuan, Hongde Wang, Dahua Y. Glutamate levels in the ventromedial prefrontal cortex and resting-state functional connectivity within reward circuits in alcohol-dependent patients. Addiction biology. vol 28. issue 4. 2023-04-05. PMID:37016753. |
however, little is known about the potential implications of glutamate levels in the prefrontal cortex on abnormal interactions within reward circuits in ad patients. |
2023-04-05 |
2023-08-14 |
Not clear |
| Karen Tangmose, Egill Rostrup, Kirsten B Bojesen, Anne Sigvard, Kasper Jessen, Louise Baruël Johansen, Birte Y Glenthøj, Mette Ødegaard Nielse. Reward disturbances in antipsychotic-naïve patients with first-episode psychosis and their association to glutamate levels. Psychological medicine. vol 53. issue 4. 2023-04-03. PMID:37010221. |
reward disturbances in antipsychotic-naïve patients with first-episode psychosis and their association to glutamate levels. |
2023-04-03 |
2023-08-14 |
Not clear |