| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J A Terró. Role of 5-ht7 receptors in the long-lasting hypotensive response induced by 5-hydroxytryptamine in the rat. British journal of pharmacology. vol 121. issue 3. 1997-08-04. PMID:9179401. |
taken together, the present pharmacological data suggest that the long-lasting vasodepressor action of 5-ht in the rat involves activation of receptors closely similar to the cloned 5-ht7 subtype. |
1997-08-04 |
2023-08-12 |
rat |
| M L Vizuete, J L Venero, E Traiffort, C Vargas, A Machado, J Can. Expression of 5-HT7 receptor mRNA in rat brain during postnatal development. Neuroscience letters. vol 227. issue 1. 1997-07-30. PMID:9178857. |
a possible non-neurotransmitter trophic function of 5-ht mediated through 5-ht7 receptors could be suggested. |
1997-07-30 |
2023-08-12 |
rat |
| M Gobbi, L Parotti, T Mennin. [3H]5-HT binding to 5-HT1nonA-nonB receptors in rat hypothalamus is not representative of 5-HT7 receptors. Annals of the New York Academy of Sciences. vol 812. 1997-07-08. PMID:9186730. |
[3h]5-ht binding to 5-ht1nona-nonb receptors in rat hypothalamus is not representative of 5-ht7 receptors. |
1997-07-08 |
2023-08-12 |
rat |
| P De Vries, S Apaydin, C M Villalón, J P Heiligers, P R Saxen. Interactions of GR127935, a 5-HT(1B/D) receptor ligand, with functional 5-HT receptors. Naunyn-Schmiedeberg's archives of pharmacology. vol 355. issue 4. 1997-06-27. PMID:9109356. |
in conclusion, the present study demonstrates that gr127935 is a selective 5-ht(1b/d) receptor antagonist devoid of interactions at 'orphan' 5-ht1-like (5-ht7? |
1997-06-27 |
2023-08-12 |
rat |
| J Erdmann, M M Nöthen, D Shimron-Abarbanell, M Rietschel, M Albus, M Borrmann, W Maier, E Franzek, J Körner, B Weigelt, R Fimmers, P Proppin. The human serotonin 7 (5-HT7) receptor gene: genomic organization and systematic mutation screening in schizophrenia and bipolar affective disorder. Molecular psychiatry. vol 1. issue 5. 1997-06-09. PMID:9154233. |
the human serotonin 7 (5-ht7) receptor gene: genomic organization and systematic mutation screening in schizophrenia and bipolar affective disorder. |
1997-06-09 |
2023-08-12 |
human |
| J Erdmann, M M Nöthen, D Shimron-Abarbanell, M Rietschel, M Albus, M Borrmann, W Maier, E Franzek, J Körner, B Weigelt, R Fimmers, P Proppin. The human serotonin 7 (5-HT7) receptor gene: genomic organization and systematic mutation screening in schizophrenia and bipolar affective disorder. Molecular psychiatry. vol 1. issue 5. 1997-06-09. PMID:9154233. |
in the present study, we evaluated the possible contribution of genetic variation of the serotonin 5-ht7 receptor to the development of schizophrenia and bipolar affective disorder. |
1997-06-09 |
2023-08-12 |
human |
| M Urbina, C Schmeer, L Lim. 5HT1A receptor agonist differentially increases cyclic AMP concentration in intact and lesioned goldfish retina. In vitro inhibition of outgrowth by forskolin. Neurochemistry international. vol 29. issue 5. 1997-05-12. PMID:8939455. |
the activation of other subtypes of 5ht receptors positively coupled to adenylate cyclase by the 5ht1a agonist, such as 5ht7, cannot be discarded. |
1997-05-12 |
2023-08-12 |
rat |
| D E Heidmann, M A Metcalf, R Kohen, M W Hambli. Four 5-hydroxytryptamine7 (5-HT7) receptor isoforms in human and rat produced by alternative splicing: species differences due to altered intron-exon organization. Journal of neurochemistry. vol 68. issue 4. 1997-04-28. PMID:9084407. |
the serotonin (5-ht) 5-ht7 receptor subtype is thought to mediate a number of physiological effects in mammalian brain and periphery. |
1997-04-28 |
2023-08-12 |
human |
| P G McLean, I M Coupar, P Molenaa. Changes in sensitivity of 5-HT receptor mediated functional responses in the rat oesophagus, fundus and jejunum following chronic infusion with 5-hydroxytryptamine. Naunyn-Schmiedeberg's archives of pharmacology. vol 354. issue 4. 1997-03-24. PMID:8897456. |
it has recently been shown in a preliminary characterisation that in rat jejunum, 5-ht produces a biphasic concentration-effect curve which is mediated by a putative 5-ht7 (first phase) and 5-ht3 (second phase) receptor mechanism. |
1997-03-24 |
2023-08-12 |
rat |
| D Goldman, J Lappalainen, N Ozak. Direct analysis of candidate genes in impulsive behaviours. Ciba Foundation symposium. vol 194. 1997-01-02. PMID:8862874. |
direct gene analyses have revealed non-conservative amino acid substitutions and structural variants (generally rare) at drd2, drd3 and drd4 dopamine receptors and 5-ht1a, 5-ht2a, 5-ht2c and 5-ht7 serotonin receptors. |
1997-01-02 |
2023-08-12 |
Not clear |
| P Schoeffter, C Ullmer, I Bobirnac, G Gabbiani, H Lübber. Functional, endogenously expressed 5-hydroxytryptamine 5-ht7 receptors in human vascular smooth muscle cells. British journal of pharmacology. vol 117. issue 6. 1996-12-11. PMID:8882587. |
functional, endogenously expressed 5-hydroxytryptamine 5-ht7 receptors in human vascular smooth muscle cells. |
1996-12-11 |
2023-08-12 |
human |
| R B Raffa, E E Cod. Lack of binding of acetaminophen to 5-HT receptor or uptake sites (or eleven other binding/uptake assays). Life sciences. vol 59. issue 2. 1996-08-30. PMID:8699917. |
in the present study, we measured the affinity of acetaminophen at 5-ht3, as well as 5-ht1a, 5-ht1b, 5-ht1d, 5-ht2, 5-ht2c, 5-ht4, 5-ht6, 5-ht7 and eleven other receptor sites and at serotonin and norepinephrine reuptake sites. |
1996-08-30 |
2023-08-12 |
Not clear |
| D J Cushing, J M Zgombick, D L Nelson, M L Cohe. LY215840, a high-affinity 5-HT7 receptor ligand, blocks serotonin-induced relaxation in canine coronary artery. The Journal of pharmacology and experimental therapeutics. vol 277. issue 3. 1996-08-06. PMID:8667223. |
the ability of ly215840 to block the relaxant 5-ht receptor in canine coronary artery may reflect its 5-ht7 receptor antagonist activity and make it a useful tool to probe the relationship between the 5-ht7 receptor and the coronary vasoactive properties of 5-ht. |
1996-08-06 |
2023-08-12 |
human |
| M Gobbi, L Parotti, T Mennin. Are 5-hydroxytryptamine7 receptors involved in [3H]5-hydroxytryptamine binding to 5-hydroxytryptamine 1nonA-nonB receptors in rat hypothalamus? Molecular pharmacology. vol 49. issue 3. 1996-07-17. PMID:8643096. |
we assayed [3h]5-hydroxytryptamine ([3h]5-ht) binding in rat hypothalamic membranes to confirm the possible of measuring 5-ht7 receptors. |
1996-07-17 |
2023-08-12 |
rat |
| D Goldma. Candidate genes in alcoholism. Clinical neuroscience (New York, N.Y.). vol 3. issue 3. 1996-06-04. PMID:8612062. |
structural polymorphisms were detected in five serotonin receptors (5ht1a, 5ht1db, 5ht2a, 5ht2c, and 5ht7). |
1996-06-04 |
2023-08-12 |
Not clear |
| C S Nelson, R D Cone, L S Robbins, C N Allen, J P Adelma. Cloning and expression of a 5HT7 receptor from Xenopus laevis. Receptors & channels. vol 3. issue 1. 1996-03-25. PMID:8589994. |
thus, xm2 encodes a 5ht receptor with sequence homology to mammalian 5ht7 receptors, a similar intracellular signal transduction and receptor pharmacology, but a broader distribution in peripheral tissues. |
1996-03-25 |
2023-08-12 |
xenopus_laevis |
| X C Li, J F Giot, D Kuhl, R Hen, E R Kande. Cloning and characterization of two related serotonergic receptors from the brain and the reproductive system of Aplysia that activate phospholipase C. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 15. issue 11. 1995-12-26. PMID:7472509. |
sequence comparison reveals that these receptors are 33.1 to 23.3% identical to the following 5-ht receptors: 5-htdro1 > 5-ht6 > 5-htlym > mouse 5-ht1b > 5-htdro2a > mouse 5-ht7 > rat 5-ht2a. |
1995-12-26 |
2023-08-12 |
mouse |
| S Hyni. [5-hydroxytryptamine (serotonin) receptors--nomenclature and classification of types and subtypes]. Ceskoslovenska fysiologie. vol 44. issue 3. 1995-12-26. PMID:7586016. |
finally, subfamily of miscellaneous 5-ht receptors contains subtypes 5-ht3, 5-ht4, 5-ht5, 5-ht6, and 5-ht7; some of them has been cloned, however, our knowledge on their function is still minimal. |
1995-12-26 |
2023-08-12 |
Not clear |
| H Y Meltze. Role of serotonin in the action of atypical antipsychotic drugs. Clinical neuroscience (New York, N.Y.). vol 3. issue 2. 1995-11-29. PMID:7583621. |
this article reviews the effects of clozapine and related antipsychotic drugs on dopamine (da) d1, d2, and d4, and serotonin (5-ht) 5-ht2a, 5-ht2c, 5-ht3, 5-ht6, and 5-ht7 receptors, as well as its ability to modulate da and 5-ht release. |
1995-11-29 |
2023-08-12 |
Not clear |
| K A Gran. The role of 5-HT3 receptors in drug dependence. Drug and alcohol dependence. vol 38. issue 2. 1995-10-19. PMID:7671767. |
since the discovery of serotonin receptor subtypes in 1957, the classification of serotonin receptors now includes 5-ht1 through 5-ht7 receptors, with further subtypes of receptors in each family. |
1995-10-19 |
2023-08-12 |
Not clear |