| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M L Defendini, M Juin, C Granie. Apamin binding sites in human C6 cell line and their accessibility to monoclonal antibodies. Neuroreport. vol 1. issue 3-4. 1991-11-08. PMID:1966607. |
i) mono 125i-iodoapamin binds to receptor sites in a human neuroglial cell line (c6 line) but not in human cell lines from pancreatic (rin5f line) and colonic origin (ht29 line). |
1991-11-08 |
2023-08-11 |
human |
| D L Stemple, D J Anderso. A Schwann cell antigen recognized by monoclonal antibody 217c is the rat low-affinity nerve growth factor receptor. Neuroscience letters. vol 124. issue 1. 1991-08-28. PMID:1649981. |
monoclonal antibody 217c was generated against an antigen expressed on the rat glial cell line, c6 glioma, 217c has been shown to recognize schwann cells in mixed cultures as well as in tissue sections and has been used to identify schwann cells independent of other markers, such as monoclonal antibody 192-igg, which recognizes the rat low affinity nerve growth factor (ngf) receptor. |
1991-08-28 |
2023-08-11 |
rat |
| S Kumar, J Huber, L A Peña, J R Perez-Polo, K Werrbach-Perez, J de Velli. Characterization of functional nerve growth factor-receptors in a CNS glial cell line: monoclonal antibody 217c recognizes the nerve growth factor-receptor on C6 glioma cells. Journal of neuroscience research. vol 27. issue 3. 1991-07-19. PMID:1965839. |
characterization of functional nerve growth factor-receptors in a cns glial cell line: monoclonal antibody 217c recognizes the nerve growth factor-receptor on c6 glioma cells. |
1991-07-19 |
2023-08-11 |
rat |
| W Kiess, L A Greenstein, L Lee, C Thomas, S P Nissle. Biosynthesis of the insulin-like growth factor-II (IGF-II)/mannose-6-phosphate receptor in rat C6 glial cells: the role of N-linked glycosylation in binding of IGF-II to the receptor. Molecular endocrinology (Baltimore, Md.). vol 5. issue 2. 1991-07-01. PMID:1645456. |
in addition, the presence of swainsonine in c6 glial cell cultures led to the formation of a 240-kda receptor hybrid molecule, which was cleaved by endo h into a 225-kda species. |
1991-07-01 |
2023-08-11 |
rat |
| T Usui, Y Nakai, T Tsukada, H Takahashi, J Fukata, Y Naito, S Nakaishi, T Tominaga, N Murakami, H Imur. Expression of the human pro-opiomelanocortin gene introduced into a rat glial cell line. Journal of molecular endocrinology. vol 4. issue 2. 1990-06-29. PMID:2160827. |
a fragment of human genomic dna containing the entire pro-opiomelanocortin (pomc) gene was introduced by transfection into the rat glial cell line c6. |
1990-06-29 |
2023-08-11 |
human |
| T Usui, Y Nakai, T Tsukada, H Takahashi, J Fukata, Y Naito, S Nakaishi, T Tominaga, N Murakami, H Imur. Expression of the human pro-opiomelanocortin gene introduced into a rat glial cell line. Journal of molecular endocrinology. vol 4. issue 2. 1990-06-29. PMID:2160827. |
the human pomc gene could thus be expressed in the non-pituitary rat glial cell line c6, although the transcripts and translation products in c6 cells differ from those in the human pituitary. |
1990-06-29 |
2023-08-11 |
human |
| J J Bernstein, W J Goldberg, E R Laws, D Conger, V Morreale, L R Woo. C6 glioma cell invasion and migration of rat brain after neural homografting: ultrastructure. Neurosurgery. vol 26. issue 4. 1990-05-29. PMID:2330084. |
c6 cells were observed on the glia limitans on the surface of the brain, in the corpus callosum, subependymal space, and perivascular space and had invaded the cortex under the implantation pocket. |
1990-05-29 |
2023-08-11 |
rat |
| T Ohnishi, P B Sher, J B Posner, W R Shapir. Capillary permeability factor secreted by malignant brain tumor. Role in peritumoral brain edema and possible mechanism for anti-edema effect of glucocorticoids. Journal of neurosurgery. vol 72. issue 2. 1990-02-21. PMID:2104924. |
conditioned media from two human malignant gliomas, c6 rat glioma, walker 256 carcinosarcoma, and normal human glia were concentrated 50-fold to create a culture supernatant (sup-c). |
1990-02-21 |
2023-08-11 |
human |
| M Paulin-Levasseur, A Scherbarth, G Giese, K Röser, W Bohn, P Trau. Expression of nuclear lamins in mammalian somatic cells lacking cytoplasmic intermediate filament proteins. Journal of cell science. vol 92 ( Pt 3). 1990-01-24. PMID:2687302. |
using immunofluorescence and immunoblotting techniques, we have examined the composition of the nuclear lamina in murine plasmacytoma cells, mpc-11, exposed to the phorbol ester tpa as well as in two cell lines devoid of cytoplasmic intermediate filament proteins, the human adrenal cortex carcinoma-derived cells sw-13 and the clone c6-m-d4 derived from the rat glial cell line c6. |
1990-01-24 |
2023-08-11 |
human |
| S C Morash, H W Cook, M W Spenc. Lysophosphatidylcholine as an intermediate in phosphatidylcholine metabolism and glycerophosphocholine synthesis in cultured cells: an evaluation of the roles of 1-acyl- and 2-acyl-lysophosphatidylcholine. Biochimica et biophysica acta. vol 1004. issue 2. 1989-09-01. PMID:2752020. |
previous studies in our laboratory have shown that the principal pathway of phosphatidylcholine (ptdcho) degradation in cultured mouse n1e-115 neuroblastoma, c6 rat glioma, primary rat brain glia and human fibroblasts is ptdcho----lysophosphatidylcholine (lysoptdcho)----glycerophosphocholine (gropcho)----glycerophosphate plus choline (morash, s.c. et al. |
1989-09-01 |
2023-08-11 |
mouse |
| T Usui, Y Nakai, T Tsukada, J Fukata, S Nakaishi, Y Naitoh, H Imur. Cyclic AMP-responsive region of the human proopiomelanocortin (POMC) gene. Molecular and cellular endocrinology. vol 62. issue 1. 1989-08-18. PMID:2545484. |
the transcriptional activity of the fusion genes introduced into the rat glial cell line c6 was assayed by measuring cat activity in the cell lysate. |
1989-08-18 |
2023-08-11 |
human |
| W Kiess, L Lee, D E Graham, L Greenstein, L Y Tseng, M M Rechler, S P Nissle. Rat C6 glial cells synthesize insulin-like growth factor I (IGF-I) and express IGF-I receptors and IGF-II/mannose 6-phosphate receptors. Endocrinology. vol 124. issue 4. 1989-05-03. PMID:2538309. |
we have used the rat c6 glial cell line as a model system to study the role of insulin-like growth factors (igf) in neuroglial cells of the central nervous system (cns). |
1989-05-03 |
2023-08-11 |
human |
| W Kiess, L Lee, D E Graham, L Greenstein, L Y Tseng, M M Rechler, S P Nissle. Rat C6 glial cells synthesize insulin-like growth factor I (IGF-I) and express IGF-I receptors and IGF-II/mannose 6-phosphate receptors. Endocrinology. vol 124. issue 4. 1989-05-03. PMID:2538309. |
competitive binding and affinity cross-linking experiments using [125]igf-i and [125i]igf-ii demonstrated the presence of igf-i receptors (type i) and igf-ii/mannose 6-phosphate receptors (type ii) on c6 glial cell membranes. |
1989-05-03 |
2023-08-11 |
human |
| W Kiess, L Lee, D E Graham, L Greenstein, L Y Tseng, M M Rechler, S P Nissle. Rat C6 glial cells synthesize insulin-like growth factor I (IGF-I) and express IGF-I receptors and IGF-II/mannose 6-phosphate receptors. Endocrinology. vol 124. issue 4. 1989-05-03. PMID:2538309. |
we were unable to demonstrate an autocrine role for igf in the c6 glial cell line, since [3h]thymidine incorporation into dna was stimulated equally well by igf-i-deficient rat serum and normal serum, and added igf did not stimulate [3h]thymidine incorporation into dna when tested alone or when added to igf-i-deficient serum. |
1989-05-03 |
2023-08-11 |
human |
| T C Ryken, J W Turner, D J Hicklin, J F Miller, B A Baggenstoss, R Li. Induction of cytoskeletal alterations in C6 glioma by glia maturation factor. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 5. issue 3. 1988-11-23. PMID:3503500. |
induction of cytoskeletal alterations in c6 glioma by glia maturation factor. |
1988-11-23 |
2023-08-11 |
rat |
| T C Ryken, J W Turner, D J Hicklin, J F Miller, B A Baggenstoss, R Li. Induction of cytoskeletal alterations in C6 glioma by glia maturation factor. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 5. issue 3. 1988-11-23. PMID:3503500. |
c6 rat glioma cells respond to glia maturation factor (gmf) with characteristic morphological alterations. |
1988-11-23 |
2023-08-11 |
rat |
| P E Spoerri, M M Rapport, S P Mahadik, F J Roise. Inhibition of conditioned media-mediated neuritogenesis of sensory ganglia by monoclonal antibodies to GM1 ganglioside. Brain research. vol 469. issue 1-2. 1988-09-15. PMID:3401809. |
the monosialoganglioside gm1 can potentiate the neuritogenic activity of media conditioned by several cell types: neonatal glia, c6 glioma, embryonic chick heart or skeletal muscle and the rat myogenic line l6. |
1988-09-15 |
2023-08-11 |
mouse |
| S C Morash, H W Cook, M W Spenc. Phosphatidylcholine metabolism in cultured cells: catabolism via glycerophosphocholine. Biochimica et biophysica acta. vol 961. issue 2. 1988-08-19. PMID:3390456. |
the catabolism of phosphatidylcholine (ptdcho) has been studied in cultured murine neuroblastoma (n1e-115), c6 glioma, rat brain primary glia, and human fibroblast cells. |
1988-08-19 |
2023-08-11 |
human |
| E Tiffany-Castiglioni, D M Garcia, J N Wu, J Zmudzki, G R Bratto. Effects of lead on viability and intracellular metal content of C6 rat glioma cells. Journal of toxicology and environmental health. vol 23. issue 2. 1988-03-25. PMID:3343700. |
the results were compared with previous findings on astroglia and oligodendroglia in culture in order to evaluate c6 cultures as a model for pb toxicity in glia. |
1988-03-25 |
2023-08-11 |
rat |
| B Niedieck, J Löhle. Expression of 3-fucosyl-N-acetyllactosamine on glia cells and its putative role in cell adhesion. Acta neuropathologica. vol 75. issue 2. 1988-03-04. PMID:2449031. |
mouse monoclonal antibodies from five clones (mma, 1g10, vim c6, mc-1 and tü9), elicited to human myeloid cells and reactive with the 3-fucosyl-n-acetyllactosamine sequence (also termed x-determinant), cross-react with glia cells from human and rat brain. |
1988-03-04 |
2023-08-11 |
mouse |