| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mariam Farrag, Alfonso Cordero-Barreal, Djedjiga Ait Eldjoudi, María Varela-García, Carlos Torrijos Pulpón, Francisca Lago, Amina Essawy, Ahmed Soffar, Jesus Pino, Yousof Farrag, Oreste Gualill. Impact of Chondrocyte Inflammation on Glial Cell Activation: The Mediating Role of Nitric Oxide. Cartilage. 2024-10-29. PMID:39469810. |
this study investigates how the inflammatory response of atdc5 murine chondrogenic cells influences the activity of c6 (rat) and gl261 (mouse) glial cell lines. |
2024-10-29 |
2024-10-31 |
mouse |
| Hương Giang Lê, Woong Kim, Jung-Mi Kang, Tuấn Cường Võ, Won Gi Yoo, Hyeonsook Cheong, Byoung-Kuk N. The anti-amoebic activity of Pinus densiflora leaf extract against the brain-eating amoeba Naegleria fowleri. Parasites, hosts and diseases. vol 62. issue 2. 2024-06-05. PMID:38835258. |
alternatively, ple did not significantly affect the viability of the rat glial cell line c6. |
2024-06-05 |
2024-06-07 |
rat |
| Yue Wang, Yue Wu, Li Li, Jin Gao, Dian Shuai Gao, Shen Su. GDNF triggers proliferation of rat C6 glioma cells via the NF-κB/CXCL1 signaling pathway. PloS one. vol 18. issue 8. 2023-08-20. PMID:37594930. |
and exogenous glial cell line-derived neurotrophic factor (gdnf) induced proliferation and up-regulated the level of cxcl1 in rat c6 glioma cells determined by sqpcr and elisa. |
2023-08-20 |
2023-09-07 |
rat |
| Luis Fernando Narváez-Pérez, Francisco Paz-Bermúdez, José Arturo Avalos-Fuentes, Aurelio Campos-Romo, Benjamín Florán-Garduño, José Segovi. CRISPR/sgRNA-directed synergistic activation mediator (SAM) as a therapeutic tool for Parkinson´s disease. Gene therapy. 2023-08-04. PMID:37542151. |
potential sgrnas within the rat th promoter region were tested, and the expression of the th protein was determined in the c6 glial cell line. |
2023-08-04 |
2023-08-14 |
rat |
| Aline H Sousa, João P G Pereira, Allan C Malaquias, Fernanda do E S Sagica, Edivaldo H C de Oliveir. Intracellular accumulation and DNA damage caused by methylmercury in glial cells. Journal of biochemical and molecular toxicology. 2022-07-13. PMID:35822649. |
thus, the aim of this study was to investigate the cytotoxic and genotoxic potential of methylmercury in cell lines derived from neurons (b103) and glia (c6), exposed to methylmercury (mehg) for 24 h, by analyzing cell viability, metabolic activity, and damage to dna and chromosomes. |
2022-07-13 |
2023-08-14 |
Not clear |
| Yessenia L Molina, David García-Seisdedos, Bohdan Babiy, Milagros Lerma, Javier Martínez-Botas, María J Casarejos, María T Vallejo, Diego Gómez-Coronado, Miguel A Lasunción, Óscar Pastor, Rebeca Bust. Rottlerin Stimulates Exosome/Microvesicle Release Via the Increase of Ceramide Levels Mediated by Ampk in an In Vitro Model of Intracellular Lipid Accumulation. Biomedicines. vol 10. issue 6. 2022-06-24. PMID:35740338. |
in a model of lipid trafficking impairment in c6 glia cells, rottlerin increased ceramide levels, while decreasing hexosylceramide content. |
2022-06-24 |
2023-08-14 |
Not clear |
| Sylwia Gul-Hinc, Anna Michno, Marlena Zyśk, Andrzej Szutowicz, Agnieszka Jankowska-Kulawy, Anna Ronowsk. Protection of Cholinergic Neurons against Zinc Toxicity by Glial Cells in Thiamine-Deficient Media. International journal of molecular sciences. vol 22. issue 24. 2021-12-24. PMID:34948135. |
low zn concentrations did not affect astroglial c6 and primary glial cell viability in thiamine-deficient conditions. |
2021-12-24 |
2023-08-13 |
Not clear |
| Pei Cai, Yi Zheng, Yilin Sun, Cuiping Zhang, Qi Zhang, Qian Li. New Blood-Brain Barrier Models Using Primary Parkinson's Disease Rat Brain Endothelial Cells and Astrocytes for the Development of Central Nervous System Drug Delivery Systems. ACS chemical neuroscience. vol 12. issue 20. 2021-10-28. PMID:34623131. |
we developed and characterized in vitro rat endothelial cell and c6 glial cell coculture bbb models. |
2021-10-28 |
2023-08-13 |
rat |
| Aakash Katdare, Dignesh Khunt, Shreya Thakkar, Surya Narayana Polaka, Manju Misr. Comparative evaluation of fish oil and butter oil in modulating delivery of galantamine hydrobromide to brain via intranasal route: pharmacokinetic and oxidative stress studies. Drug delivery and translational research. vol 10. issue 4. 2021-08-02. PMID:32219727. |
cell-based oxidative stress assays and pharmacokinetic studies were performed using c6 glial cell lines, and sprague dawley rats, respectively. |
2021-08-02 |
2023-08-13 |
rat |
| Yoshiko Furukawa, Yu-Suke Washimi, Ryu-Ichi Hara, Mizuki Yamaoka, Satoshi Okuyama, Atsushi Sawamoto, Mitsunari Nakajim. Citrus Auraptene Induces Expression of Brain-Derived Neurotrophic Factor in Neuro2a Cells. Molecules (Basel, Switzerland). vol 25. issue 5. 2020-12-14. PMID:32138196. |
(1) background: our published data have indicated that 1) auraptene (aur), a citrus ingredient, has neuroprotective effects on the mouse brain, owing to its ability to suppress inflammation, such as causing a reduction in hyperactivation of microglia and astrocytes; 2) aur has the ability to trigger phosphorylation (activation) of extracellular signal-related kinase (erk) and camp response element-binding protein (creb) in neuronal cells; 3) aur has the ability to induce glial cell line-derived neurotrophic factor (gdnf) synthesis/secretion in rat c6 glioma cells. |
2020-12-14 |
2023-08-13 |
mouse |
| David García-Seisdedos, Bohdan Babiy, Milagros Lerma, María E Casado, Javier Martínez-Botas, Miguel A Lasunción, Óscar Pastor, Rebeca Bust. Curcumin stimulates exosome/microvesicle release in an in vitro model of intracellular lipid accumulation by increasing ceramide synthesis. Biochimica et biophysica acta. Molecular and cell biology of lipids. vol 1865. issue 5. 2020-10-27. PMID:31988047. |
in a model of lipid trafficking impairment in c6 glia cells, we show that curcumin stimulated ceramide synthesis by increasing the intracellular concentration of ceramide-dihydroceramide. |
2020-10-27 |
2023-08-13 |
mouse |
| Gökhan Kuş, Mete Özkurt, Pınar Öztopcu Vatan, Nilüfer Erkasap, Ruhi Uyar, Selda Kabader. Comparison of a ceramidase inhibitor (ceranib-2) with C2 ceramide and cisplatin on cytotoxicity and apoptosis of glioma cells. Turkish journal of biology = Turk biyoloji dergisi. vol 42. issue 3. 2020-10-01. PMID:30814888. |
uhts, we examined the possible role of ceranib-2, a novel ceramidase inhibitor, on growth and apoptotic mechanisms of the human normal glia cell line (hna), human glioma cell lines (t-98g and u-87mg), and a rat glioma cell line (c6). |
2020-10-01 |
2023-08-13 |
human |
| Yoshiko Furukawa, Ryu-Ichi Hara, Makiko Nakaya, Satoshi Okuyama, Atsushi Sawamoto, Mitsunari Nakajim. Citrus Auraptene Induces Glial Cell Line-Derived Neurotrophic Factor in C6 Cells. International journal of molecular sciences. vol 21. issue 1. 2020-05-18. PMID:31905925. |
citrus auraptene induces glial cell line-derived neurotrophic factor in c6 cells. |
2020-05-18 |
2023-08-13 |
mouse |
| Yoshiko Furukawa, Ryu-Ichi Hara, Makiko Nakaya, Satoshi Okuyama, Atsushi Sawamoto, Mitsunari Nakajim. Citrus Auraptene Induces Glial Cell Line-Derived Neurotrophic Factor in C6 Cells. International journal of molecular sciences. vol 21. issue 1. 2020-05-18. PMID:31905925. |
the present study showed that treatment with aur significantly increased the release of glial cell line-derived neurotrophic factor (gdnf), in a dose- and time-dependent manner, by rat c6 glioma cells, which release was associated with increased expression of gdnf mrna. |
2020-05-18 |
2023-08-13 |
mouse |
| Aisa Ozawa, Erina Kadowaki, Tomoyo Horio, Motoharu Sakau. Acetylcholine suppresses the increase of glia fibrillary acidic protein expression via acetylcholine receptors in cAMP-induced astrocytic differentiation of rat C6 glioma cells. Neuroscience letters. vol 698. 2019-09-10. PMID:30639397. |
acetylcholine suppresses the increase of glia fibrillary acidic protein expression via acetylcholine receptors in camp-induced astrocytic differentiation of rat c6 glioma cells. |
2019-09-10 |
2023-08-13 |
rat |
| Aisa Ozawa, Erina Kadowaki, Tomoyo Horio, Motoharu Sakau. Acetylcholine suppresses the increase of glia fibrillary acidic protein expression via acetylcholine receptors in cAMP-induced astrocytic differentiation of rat C6 glioma cells. Neuroscience letters. vol 698. 2019-09-10. PMID:30639397. |
our present study revealed that in the camp-induced differentiation of c6 cells, an achr antagonist alleviated the expression of glia fibrillary acidic protein (gfap) that had been suppressed by dichlorvos (ddvp), an organophosphate and an ache inhibitor. |
2019-09-10 |
2023-08-13 |
rat |
| Doudou Luo, Yali Zhang, Xiaoqian Yuan, Yilin Pan, Lichao Yang, Yun Zhao, Rengong Zhuo, Caixia Chen, Lu Peng, Wenjun Li, Xin Jin, Yu Zho. Oleoylethanolamide inhibits glial activation via moudulating PPARα and promotes motor function recovery after brain ischemia. Pharmacological research. vol 141. 2019-08-23. PMID:30660821. |
glial scar formation in vitro model was induced by transforming growth factor β1 (tgf-β1) in c6 glial cell culture, and experiment model in vivo was induced by middle cerebral artery occlusion (mcao) in mice. |
2019-08-23 |
2023-08-13 |
mouse |
| Theodore A Slotkin, Samantha Skavicus, Frederic J Seidle. Developmental neurotoxicity resulting from pharmacotherapy of preterm labor, modeled in vitro: Terbutaline and dexamethasone, separately and together. Toxicology. vol 400-401. 2019-01-15. PMID:29524569. |
at later stages, dexamethasone promoted glial cell differentiation (c6 cells), while shifting neuronal cell differentiation so as to distort the balance of neurotransmitter phenotypes (pc12 cells). |
2019-01-15 |
2023-08-13 |
Not clear |
| Gagandeep Kaur, Ravi P Cholia, Gaurav Joshi, Suyog M Amrutkar, Sourav Kalra, Anil K Mantha, Uttam C Banerjee, Raj Kuma. Anticancer activity of dihydropyrazolo[1,5-c]quinazolines against rat C6 glioma cells via inhibition of topoisomerase II. Archiv der Pharmazie. vol 351. issue 6. 2018-10-03. PMID:29737542. |
the compounds were investigated for their antiproliferative activity against the c6 rat glial cell line. |
2018-10-03 |
2023-08-13 |
human |
| Xiaoshuang Wang, Liu Yang, Li Yang, Faping Xing, Hua Yang, Liyue Qin, Yunyi Lan, Hui Wu, Beibei Zhang, Hailian Shi, Cheng Lu, Fei Huang, Xiaojun Wu, Zhengtao Wan. Gypenoside IX Suppresses p38 MAPK/Akt/NFκB Signaling Pathway Activation and Inflammatory Responses in Astrocytes Stimulated by Proinflammatory Mediators. Inflammation. vol 40. issue 6. 2018-07-10. PMID:28822019. |
gp ix significantly reduced the production of inducible nitric oxide synthase (inos), cyclooxygenase-2 (cox-2), tumor necrosis factor-α (tnf-α), interleukin-6 (il-6), and interleukin-1β (il-1β) at either protein or mrna level in glial cell line c6 cells stimulated by lipopolysaccharide (lps)/tnf-α combination. |
2018-07-10 |
2023-08-13 |
mouse |