| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Rita Di Benedetto, Michela Alessandra Denti, Serafina Salvati, Massimo Sanchez, Lucilla Attorri, Giulia David, Antonella Di Bias. RNAi-mediated silencing of ABCD3 gene expression in rat C6 glial cells: a model system to study PMP70 function. Neurochemistry international. vol 52. issue 6. 2008-07-28. PMID:18178290. |
we used the rna interference technique, a powerful approach to loss-of-function gene expression analysis, to knockdown the abcd3 gene in the rat glial c6 cell line, since glia could represent the target tissue of x-linked adrenoleukodystrophy disease. |
2008-07-28 |
2023-08-12 |
rat |
| Birthe Smolinsky, Sabrina A Eichler, Sabine Buchmeier, Jochen C Meier, Guenter Schwar. Splice-specific functions of gephyrin in molybdenum cofactor biosynthesis. The Journal of biological chemistry. vol 283. issue 25. 2008-07-25. PMID:18411266. |
subsequent analysis of cultured neurons and glia cells demonstrated glial moco synthesis due to the expression of gephyrins containing the cassettes c2 and c6 with and without c3.1. |
2008-07-25 |
2023-08-12 |
Not clear |
| Kyoji Morita, Song He. Progesterone pretreatment enhances serotonin-stimulated BDNF gene expression in rat c6 glioma cells through production of 5alpha-reduced neurosteroids. Journal of molecular neuroscience : MN. vol 34. issue 3. 2008-06-20. PMID:18219447. |
then, we have investigated the direct actions of neurotransmitters on glial cell metabolism and function using rat c6 glioma cells as an in vitro model system and suggested that these neurotransmitters induce their differentiation probably through the production of 5alpha-reduced neurosteroids. |
2008-06-20 |
2023-08-12 |
rat |
| Kazue Hisaoka, Natsuko Maeda, Mami Tsuchioka, Minoru Takebayash. Antidepressants induce acute CREB phosphorylation and CRE-mediated gene expression in glial cells: a possible contribution to GDNF production. Brain research. vol 1196. 2008-05-30. PMID:18234163. |
we previously showed that antidepressants increased glial cell line-derived neurotrophic factor (gdnf) expression, which was dependent on acute activation of protein tyrosine kinase (ptk) and extracellular signal-regulated kinase (erk) in rat c6 glioma cells (c6 cells) and normal human astrocytes (nha). |
2008-05-30 |
2023-08-12 |
human |
| Shan-hui Hsu, Po Seng Lu, Hsiao-Chiang Ni, Chien-Hsiang S. Fabrication and evaluation of microgrooved polymers as peripheral nerve conduits. Biomedical microdevices. vol 9. issue 5. 2007-10-19. PMID:17562182. |
in this study, microgrooves on chitosan or poly(d,l-lactide) (pla) were fabricated and the behaviors of schwann cells and glial cell line c6 on these surfaces were examined. |
2007-10-19 |
2023-08-12 |
rat |
| Seiji Bruce Shibata, Yasunori Osumi, Masao Yagi, Seiji Kanda, Kohei Kawamoto, Hiromichi Kuriyama, Toshimasa Nishiyama, Toshio Yamashit. Administration of amitriptyline attenuates noise-induced hearing loss via glial cell line-derived neurotrophic factor (GDNF) induction. Brain research. vol 1144. 2007-06-13. PMID:17331482. |
amitriptyline (at), a tricyclic antidepressant agent, has been reported in recent studies to induce glial cell line-derived neurotrophic factor (gdnf) synthesis and release in rat c6 glioblastoma cells. |
2007-06-13 |
2023-08-12 |
human |
| Kazue Hisaoka, Minoru Takebayashi, Mami Tsuchioka, Natsuko Maeda, Yoshihiro Nakata, Shigeto Yamawak. Antidepressants increase glial cell line-derived neurotrophic factor production through monoamine-independent activation of protein tyrosine kinase and extracellular signal-regulated kinase in glial cells. The Journal of pharmacology and experimental therapeutics. vol 321. issue 1. 2007-05-14. PMID:17210798. |
we previously reported that antidepressants increase glial cell line-derived neurotrophic factor (gdnf) production in rat c6 glioma cells (c6 cells). |
2007-05-14 |
2023-08-12 |
human |
| Vincenza Rita Lo Vasco, Cinzia Fabrizi, Marco Artico, Lucio Cocco, Anna Maria Billi, Lorenzo Fumagalli, Francesco Antonio Manzol. Expression of phosphoinositide-specific phospholipase C isoenzymes in cultured astrocytes. Journal of cellular biochemistry. vol 100. issue 4. 2007-04-16. PMID:17063484. |
in the present experiments we investigated astrocytic plc isoforms in astrocytes obtained from foetal primary cultures of rat brain and from an established cultured (c6) rat astrocytoma cell line, two well known cell models for experimental studies on glia. |
2007-04-16 |
2023-08-12 |
rat |
| Fukka You, Yosuke Osawa, Shin-ichiro Hayashi, Shigeru Nakashim. Immediate early gene IEX-1 induces astrocytic differentiation of U87-MG human glioma cells. Journal of cellular biochemistry. vol 100. issue 1. 2007-02-28. PMID:16960879. |
glial cell differentiation was used to examine in rat c6 glioma cell line, since this cell line express astrocytic phenotypes by increase in intracellular camp concentration. |
2007-02-28 |
2023-08-12 |
human |
| Hai Yu, Kentaro Oh-Hashi, Tatsuhide Tanaka, Aihua Sai, Makoto Inoue, Yoko Hirata, Kazutoshi Kiuch. Rehmannia glutinosa induces glial cell line-derived neurotrophic factor gene expression in astroglial cells via cPKC and ERK1/2 pathways independently. Pharmacological research. vol 54. issue 1. 2006-09-29. PMID:16600621. |
among four herbs of traditional chinese medicines (tcms) used in the therapy of dementia, rehmannia glutinosa (rg) was found to induce the gene expression of glial cell line-derived neurotrophic factor (gdnf) in c6 glioblastoma cells and primary cultured astrocytes. |
2006-09-29 |
2023-08-12 |
Not clear |
| Kyoji Morita, Hideki Arimochi, Hiroyuki Itoh, Song He. Possible involvement of 5alpha-reduced neurosteroids in adrenergic and serotonergic stimulation of GFAP gene expression in rat C6 glioma cells. Brain research. vol 1085. issue 1. 2006-08-10. PMID:16581042. |
influence of adrenergic and serotonergic stimulation on glial fibrillary acidic protein (gfap) gene expression in rat c6 glioma cells was first examined as an in vitro model experiment for investigating the neuronal regulation of glial cell differentiation. |
2006-08-10 |
2023-08-12 |
rat |
| Kyoji Morita, Hideki Arimochi, Hiroyuki Itoh, Song He. Possible involvement of 5alpha-reduced neurosteroids in adrenergic and serotonergic stimulation of GFAP gene expression in rat C6 glioma cells. Brain research. vol 1085. issue 1. 2006-08-10. PMID:16581042. |
these findings suggest that both adrenergic and serotonergic stimulation may indirectly activate gfap gene expression probably through the production of 5alpha-reduced steroid metabolites in rat c6 glioma cells, proposing the possibility that 5alpha-reduced neurosteroids may play a potential role in the neuronal regulation of glial cell differentiation. |
2006-08-10 |
2023-08-12 |
rat |
| Albert Lai, Dung-Nghi Le, William A Paznekas, Wes D Gifford, Ethylin Wang Jabs, Andrew C Charle. Oculodentodigital dysplasia connexin43 mutations result in non-functional connexin hemichannels and gap junctions in C6 glioma cells. Journal of cell science. vol 119. issue Pt 3. 2006-06-13. PMID:16418219. |
to understand how oddd-associated mutations affect cx43 signaling in cells of glial origin, we conducted studies in rat c6 glioma cells, a communication-deficient glial cell line that expresses low levels of cx43. |
2006-06-13 |
2023-08-12 |
human |
| Anne-Sophie Caumont, Jean-Noël Octave, Emmanuel Herman. Specific regulation of rat glial cell line-derived neurotrophic factor gene expression by riluzole in C6 glioma cells. Journal of neurochemistry. vol 97. issue 1. 2006-05-18. PMID:16524382. |
specific regulation of rat glial cell line-derived neurotrophic factor gene expression by riluzole in c6 glioma cells. |
2006-05-18 |
2023-08-12 |
rat |
| Joshua W Gatson, Paramjit Kaur, Meharvan Sing. Dihydrotestosterone differentially modulates the mitogen-activated protein kinase and the phosphoinositide 3-kinase/Akt pathways through the nuclear and novel membrane androgen receptor in C6 cells. Endocrinology. vol 147. issue 4. 2006-04-14. PMID:16410299. |
in this study, using a glial cell model (c6 cells) that we found to express the ar, we identified that dht increased the phosphorylation of both erk and akt, key effectors of the neuroprotection-associated mapk and phosphoinositide 3-kinase signaling pathways, respectively, and erk phosphorylation was blocked by the ar antagonist, flutamide. |
2006-04-14 |
2023-08-12 |
Not clear |
| E A Sribnick, S K Ray, N L Bani. Estrogen prevents glutamate-induced apoptosis in C6 glioma cells by a receptor-mediated mechanism. Neuroscience. vol 137. issue 1. 2006-04-05. PMID:16289585. |
to assess the protective effects of estrogen on glia, c6 rat glioma cells were treated for 24 h with 500 microm glutamate. |
2006-04-05 |
2023-08-12 |
rat |
| Anne-Sophie Caumont, Jean-Noël Octave, Emmanuel Herman. Amantadine and memantine induce the expression of the glial cell line-derived neurotrophic factor in C6 glioma cells. Neuroscience letters. vol 394. issue 3. 2006-03-30. PMID:16298481. |
amantadine and memantine induce the expression of the glial cell line-derived neurotrophic factor in c6 glioma cells. |
2006-03-30 |
2023-08-12 |
rat |
| Zongjun Shao, Lillian E Dyck, Haitao Wang, Xin-Min L. Antipsychotic drugs cause glial cell line-derived neurotrophic factor secretion from C6 glioma cells. Journal of psychiatry & neuroscience : JPN. vol 31. issue 1. 2006-03-21. PMID:16496033. |
antipsychotic drugs cause glial cell line-derived neurotrophic factor secretion from c6 glioma cells. |
2006-03-21 |
2023-08-12 |
rat |
| Hideki Arimochi, Kyoji Morit. High salt culture conditions suppress proliferation of rat C6 glioma cell by arresting cell-cycle progression at S-phase. Journal of molecular neuroscience : MN. vol 27. issue 3. 2006-02-06. PMID:16280599. |
as one of the in vitro model experiments for investigating a possible effect of extracellular environmental stresses on glial cell proliferation, the influence of high salt culture conditions on the growth of rat c6 glioma cells was examined. |
2006-02-06 |
2023-08-12 |
rat |
| Shucui Jiang, Mohammad I Khan, Yao Lu, Eva S Werstiuk, Michel P Rathbon. Acceleration of blood-brain barrier formation after transplantation of enteric glia into spinal cords of rats. Experimental brain research. vol 162. issue 1. 2005-06-30. PMID:15599730. |
furthermore, most 3t3 or c6 control cells had died at 2 months and those that survived, unlike enteric glia, had no anatomical relationship to blood vessels. |
2005-06-30 |
2023-08-12 |
rat |