| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G R Cookman, C M Rega. Studies of the antiproliferative action of inorganic lead in relation to the phases of the rat glial cell cycle. Toxicology in vitro : an international journal published in association with BIBRA. vol 5. issue 2. 2012-10-02. PMID:20732006. |
inorganic lead inhibited proliferation of the c6 glial cell line with an ic(50) value of 5 x 10(-5)m-lead chloride. |
2012-10-02 |
2023-08-12 |
rat |
| Susan Noell, Rainer Ritz, Karen Wolburg-Buchholz, Hartwig Wolburg, Petra Fallier-Becke. An allograft glioma model reveals the dependence of aquaporin-4 expression on the brain microenvironment. PloS one. vol 7. issue 5. 2012-09-19. PMID:22590566. |
aqp4 staining in vivo normally is polarized in the astrocytic endfoot membranes at the glia limitans superficialis and perivascularis, but in c6 and rg2 tumors the aqp4 staining is redistributed over the whole glioma cell as in human glioblastoma. |
2012-09-19 |
2023-08-12 |
mouse |
| Jinghan Huang, Gillian Vogel, Zhenbao Yu, Guillermina Almazan, Stéphane Richar. Type II arginine methyltransferase PRMT5 regulates gene expression of inhibitors of differentiation/DNA binding Id2 and Id4 during glial cell differentiation. The Journal of biological chemistry. vol 286. issue 52. 2012-02-27. PMID:22041901. |
in addition, the prmt5-depleted oligodendrocyte progenitor and c6 glioma cells expressed high levels of the inhibitors of differentiation/dna binding, id2 and id4, known repressors of glial cell differentiation. |
2012-02-27 |
2023-08-12 |
mouse |
| Mami Tsuchioka, Kazue Hisaoka, Ryoya Yano, Chiyo Shibasaki, Naoto Kajiatani, Minoru Takebayash. Riluzole-induced glial cell line-derived neurotrophic factor production is regulated through fibroblast growth factor receptor signaling in rat C6 glioma cells. Brain research. vol 1384. 2011-07-19. PMID:21295555. |
riluzole-induced glial cell line-derived neurotrophic factor production is regulated through fibroblast growth factor receptor signaling in rat c6 glioma cells. |
2011-07-19 |
2023-08-12 |
rat |
| Mami Tsuchioka, Kazue Hisaoka, Ryoya Yano, Chiyo Shibasaki, Naoto Kajiatani, Minoru Takebayash. Riluzole-induced glial cell line-derived neurotrophic factor production is regulated through fibroblast growth factor receptor signaling in rat C6 glioma cells. Brain research. vol 1384. 2011-07-19. PMID:21295555. |
this study investigated the mechanism of riluzole-induced glial cell line-derived neurotrophic factor (gdnf) production in rat c6 glioma cells (c6 cells), a model of astrocytes. |
2011-07-19 |
2023-08-12 |
rat |
| Shinji Amano, Chunyu Gu, Shinichiro Koizumi, Tsutomu Tokuyama, Hiroki Namb. Tumoricidal bystander effect in the suicide gene therapy using mesenchymal stem cells does not injure normal brain tissues. Cancer letters. vol 306. issue 1. 2011-07-05. PMID:21450400. |
rat msctk and c6 glioma cells were mixed and seeded on the rat primary neuron and glia co-culture in the medium containing gcv to generate the bystander effect and the numbers of background cells were counted on day 0, 2 and 7. |
2011-07-05 |
2023-08-12 |
rat |
| Paolo Manca, Valentina Chis. Testosterone attenuates morpho-functional alterations by 2-methoxyestradiol exposure and induces differentiation in C6 cells. Journal of cellular physiology. vol 226. issue 6. 2011-05-16. PMID:20945387. |
here, we investigated the ability of t to attenuate the cytotoxic effects of 2me and to induce cell differentiation in an immortalized rat glial cell line, known as c6. |
2011-05-16 |
2023-08-12 |
mouse |
| Omozuanvbo R Aisiku, Loren W Runnels, Suzanne Scarlat. Identification of a novel binding partner of phospholipase cβ1: translin-associated factor X. PloS one. vol 5. issue 11. 2011-04-27. PMID:21124736. |
in c6 glia cells, endogenous plcβ1 and trax colocalize in the cytosol and the nucleus, but not on the plasma membrane where trax is absent. |
2011-04-27 |
2023-08-12 |
Not clear |
| Hang Do, Nam-Sung Kang, Suhkneung Pyo, Timothy R Billiar, Eun-Hwa Soh. Differential regulation by fucoidan of IFN-γ-induced NO production in glial cells and macrophages. Journal of cellular biochemistry. vol 111. issue 5. 2011-03-28. PMID:20830678. |
we examined the effect of fucoidan on no production induced by ifn-γ and the molecular mechanisms underlying these effects in two types of cells including glia (c6, bv-2) and macrophages (raw264.7, peritoneal primary cells). |
2011-03-28 |
2023-08-12 |
Not clear |
| Parvinder Kaur, Lars Evje, Michael Aschner, Tore Syverse. The in vitro effects of Trolox on methylmercury-induced neurotoxicity. Toxicology. vol 276. issue 1. 2010-09-08. PMID:20637824. |
the amount of mehg-induced ros was significantly reduced (p<0.05) after treatment with 50mum trolox in c6 glial cell line. |
2010-09-08 |
2023-08-12 |
Not clear |
| Parvinder Kaur, Lars Evje, Michael Aschner, Tore Syverse. The in vitro effects of Trolox on methylmercury-induced neurotoxicity. Toxicology. vol 276. issue 1. 2010-09-08. PMID:20637824. |
the mehg and trolox treated c6 glial cell line differed significantly (p<0.05) from the b35 cell line for mtt, ros and gsh activity. |
2010-09-08 |
2023-08-12 |
Not clear |
| Parvinder Kaur, Lars Evje, Michael Aschner, Tore Syverse. The in vitro effects of Trolox on methylmercury-induced neurotoxicity. Toxicology. vol 276. issue 1. 2010-09-08. PMID:20637824. |
these findings provide experimental evidence that preincubation with trolox prevents mehg-induced ros generation in c6 glial cell line by quenching of free radicals and not by changes in intracellular gsh or mehg content. |
2010-09-08 |
2023-08-12 |
Not clear |
| Q L Zhang, Q Niu, P Y Niu, Y T Shi, C Y Liu, M Di Gioacchino, L Zhang, C Zhang, M Brag. Bax gene silencing: a potential intervention in aluminum-induced neural cell death. Journal of biological regulators and homeostatic agents. vol 24. issue 1. 2010-06-22. PMID:20385067. |
to investigate whether bax rna interference (rnai) may serve as a potential intervention in neural cell death induced by aluminum, we herein established aluminum (al)-treated gliatoma (c6) cells as a model for evaluating neurotoxic injury on normal glia. |
2010-06-22 |
2023-08-12 |
Not clear |
| Paul A Constable, John G Lawrenso. Glial cell factors and the outer blood retinal barrier. Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists). vol 29. issue 5. 2010-02-22. PMID:19689550. |
the aim of this study was to examine the changes in the trans-epithelial resistance (ter), as a measure of barrier integrity, on cell lines of epithelial origin (ecv304 and arpe-19) following co-culture with glial cell lines (c6 and mio-m1) or with the addition of medium conditioned by these cells. |
2010-02-22 |
2023-08-12 |
Not clear |
| Midori Hiramatsu, Tomoko Takahashi, Makiko Komatsu, Toshitaka Kido, Yoshimasa Kasahar. Antioxidant and neuroprotective activities of Mogami-benibana (safflower, Carthamus tinctorius Linne). Neurochemical research. vol 34. issue 4. 2009-06-03. PMID:19082884. |
mogami-benibana petal extract inhibited glutamate-induced c6 glia cell death, significantly decreased the formation of malondialdehyde in mouse cerebrum, and inhibited the increase in thiobarbituric acid reactive substances and 8-hydroxy-2'-deoxyguanosine (8-ohdg) in the cerebral cortex of rats subjected to an injection of fecl(3) solution into the sensory motor cortex. |
2009-06-03 |
2023-08-12 |
mouse |
| Ganesh Baskey, Abhishek Singh, Rakhi Sharma, Birendra Nath Mallic. REM sleep deprivation-induced noradrenaline stimulates neuronal and inhibits glial Na-K ATPase in rat brain: in vivo and in vitro studies. Neurochemistry international. vol 54. issue 1. 2009-04-24. PMID:19013490. |
the results showed that neuron and neuro2a as well as glia and c6 possess comparable na-k atpase activity. |
2009-04-24 |
2023-08-12 |
rat |
| Florian Ringel, Nikolaus Plesnil. Expression and functional role of potassium-chloride cotransporters (KCC) in astrocytes and C6 glioma cells. Neuroscience letters. vol 442. issue 3. 2008-10-21. PMID:18638521. |
pcr revealed the expression of kcc isoforms in a glial cell line (c6) and primary cultured astrocytes. |
2008-10-21 |
2023-08-12 |
Not clear |
| Andrea V Leisewitz, Carolina R Urrutia, Gabriela R Martinez, Gloria Loyola, Miguel Bronfma. A PPARs cross-talk concertedly commits C6 glioma cells to oligodendrocytes and induces enzymes involved in myelin synthesis. Journal of cellular physiology. vol 217. issue 2. 2008-09-12. PMID:18543250. |
to assess a possible interaction between ppars in glial cell differentiation we used the undifferentiated c6 glioma cell line as model. |
2008-09-12 |
2023-08-12 |
Not clear |
| Mami Tsuchioka, Minoru Takebayashi, Kazue Hisaoka, Natsuko Maeda, Yoshihiro Nakat. Serotonin (5-HT) induces glial cell line-derived neurotrophic factor (GDNF) mRNA expression via the transactivation of fibroblast growth factor receptor 2 (FGFR2) in rat C6 glioma cells. Journal of neurochemistry. vol 106. issue 1. 2008-08-19. PMID:18363829. |
serotonin (5-ht) induces glial cell line-derived neurotrophic factor (gdnf) mrna expression via the transactivation of fibroblast growth factor receptor 2 (fgfr2) in rat c6 glioma cells. |
2008-08-19 |
2023-08-12 |
rat |
| Mami Tsuchioka, Minoru Takebayashi, Kazue Hisaoka, Natsuko Maeda, Yoshihiro Nakat. Serotonin (5-HT) induces glial cell line-derived neurotrophic factor (GDNF) mRNA expression via the transactivation of fibroblast growth factor receptor 2 (FGFR2) in rat C6 glioma cells. Journal of neurochemistry. vol 106. issue 1. 2008-08-19. PMID:18363829. |
we previously reported that serotonin (5-ht) increased glial cell line-derived neurotrophic factor (gdnf) release in a 5-ht(2) receptor (5-ht(2)r) and mitogen-activated protein kinase kinase/extracellular signal-related kinase (mek/erk)-dependent manner in rat c6 glioma cells (c6 cells), a model of astrocytes. |
2008-08-19 |
2023-08-12 |
rat |