| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ah Young Lee, Myoung Hee Lee, Sanghyun Lee, Eun Ju Ch. Neuroprotective Effect of Alpha-Linolenic Acid against Aβ-Mediated Inflammatory Responses in C6 Glial Cell. Journal of agricultural and food chemistry. vol 66. issue 19. 2018-05-29. PMID:29668263. |
neuroprotective effect of alpha-linolenic acid against aβ-mediated inflammatory responses in c6 glial cell. |
2018-05-29 |
2023-08-13 |
Not clear |
| Lidan Luo, Seung-Woo Kim, Hye-Kyung Lee, Il-Doo Kim, Hahnbie Lee, Ja-Kyeong Le. Anti-oxidative effects of 4-hydroxybenzyl alcohol in astrocytes confer protective effects in autocrine and paracrine manners. PloS one. vol 12. issue 5. 2017-09-08. PMID:28489907. |
in addition, 4-hba-conditioned astrocyte culture medium was found to have neuroprotective effects on primary neuronal cultures or fresh c6 cells exposed to oxidative stress, and these effects seemed to be mediated by glial cell line-derived neurotrophic factor (gdnf) and vascular endothelial growth factor (vegf), which both accumulated in 4-hba-treated astrocyte culture media. |
2017-09-08 |
2023-08-13 |
Not clear |
| Hiromi Abe, Kazue Hisaoka-Nakashima, Naoto Kajitani, Mami Okada-Tsuchioka, Ryoya Yano, Kei Itagaki, Chiyo Shibasaki, Norimitsu Morioka, Yoshihiro Nakata, Minoru Takebayash. The expression of glial cell line-derived neurotrophic factor mRNA by antidepressants involves matrix metalloproteinase-9 activation in rat astroglial cells. Biochemical and biophysical research communications. vol 479. issue 4. 2017-06-02. PMID:27678293. |
previous studies demonstrated that the release of glial cell line-derived neurotrophic factor (gdnf) induced by the tricyclic antidepressant amitriptyline was significantly inhibited by a broad-spectrum matrix metalloproteinase (mmp) inhibitor in rat c6 astroglial cells (c6 cells). |
2017-06-02 |
2023-08-13 |
rat |
| Mahesh Ramalingam, Sung-Jin Ki. Protective effects of activated signaling pathways by insulin on C6 glial cell model of MPP Journal of receptor and signal transduction research. vol 37. issue 1. 2017-04-25. PMID:27137951. |
protective effects of activated signaling pathways by insulin on c6 glial cell model of mpp parkinson's disease (pd) is the second most common neurodegenerative disorder after alzheimer's disease (ad) associated with mitochondrial dysfunction mediated by oxidative stress. |
2017-04-25 |
2023-08-13 |
Not clear |
| Kai Yao, Junfeng Wu, Jianfeng Zhang, Jimei Bo, Zhen Hong, Hengbing Z. Protective Effect of DHT on Apoptosis Induced by U18666A via PI3K/Akt Signaling Pathway in C6 Glial Cell Lines. Cellular and molecular neurobiology. vol 36. issue 5. 2017-03-24. PMID:26340949. |
protective effect of dht on apoptosis induced by u18666a via pi3k/akt signaling pathway in c6 glial cell lines. |
2017-03-24 |
2023-08-13 |
Not clear |
| Ting Li, Jianya Zhao, Jianbin Ge, Jianbin Yang, Xinjian Song, Cheng Wang, Jiamin Mao, Yan Zhang, Ye Zou, Yanmei Liu, Gang Che. Particulate Matter Facilitates C6 Glioma Cells Activation and the Release of Inflammatory Factors Through MAPK and JAK2/STAT3 Pathways. Neurochemical research. vol 41. issue 8. 2017-03-03. PMID:27068033. |
the glial cell strain c6 was cloned from a rat glioma which was induced by n-nitrosomethylurea. |
2017-03-03 |
2023-08-13 |
rat |
| Lelin Bing, Junfeng Wu, Jianfeng Zhang, Yinghui Chen, Zhen Hong, Hengbing Z. DHT inhibits the Aβ25-35-induced apoptosis by regulation of seladin-1, survivin, XIAP, bax, and bcl-xl expression through a rapid PI3-K/Akt signaling in C6 glial cell lines. Neurochemical research. vol 40. issue 1. 2015-11-10. PMID:25347962. |
dht inhibits the aβ25-35-induced apoptosis by regulation of seladin-1, survivin, xiap, bax, and bcl-xl expression through a rapid pi3-k/akt signaling in c6 glial cell lines. |
2015-11-10 |
2023-08-13 |
Not clear |
| Lelin Bing, Junfeng Wu, Jianfeng Zhang, Yinghui Chen, Zhen Hong, Hengbing Z. DHT inhibits the Aβ25-35-induced apoptosis by regulation of seladin-1, survivin, XIAP, bax, and bcl-xl expression through a rapid PI3-K/Akt signaling in C6 glial cell lines. Neurochemical research. vol 40. issue 1. 2015-11-10. PMID:25347962. |
in this study using a c6 glial cell model, apoptotic cells were detected by flow cytometry. |
2015-11-10 |
2023-08-13 |
Not clear |
| Lelin Bing, Junfeng Wu, Jianfeng Zhang, Yinghui Chen, Zhen Hong, Hengbing Z. DHT inhibits the Aβ25-35-induced apoptosis by regulation of seladin-1, survivin, XIAP, bax, and bcl-xl expression through a rapid PI3-K/Akt signaling in C6 glial cell lines. Neurochemical research. vol 40. issue 1. 2015-11-10. PMID:25347962. |
collectively, in a c6 glial cell model, we firstly found that dht inhibits aβ25-35-induced apoptosis by a rapid nongenic pi-3k/akt activation as well as regulation of seladin-1, survivin, xiap, bcl-xl, and bax proteins. |
2015-11-10 |
2023-08-13 |
Not clear |
| Severina Pacifico, Marialuisa Gallicchio, Peter Lorenz, Sarina M Duckstein, Nicoletta Potenza, Silvia Galasso, Sabina Marciano, Antonio Fiorentino, Florian C Stintzing, Pietro Monac. Neuroprotective potential of Laurus nobilis antioxidant polyphenol-enriched leaf extracts. Chemical research in toxicology. vol 27. issue 4. 2015-09-15. PMID:24547959. |
in order to evaluate the preparation of safe and nontoxic extracts, mtt, srb, and ldh assays toward sh-5ysy and sk-n-be(2)-c human neuronal cell lines, as well as on c6 mouse glial cell line, were performed. |
2015-09-15 |
2023-08-12 |
mouse |
| Severina Pacifico, Simona Piccolella, Sabina Marciano, Silvia Galasso, Paola Nocera, Vincenzo Piscopo, Antonio Fiorentino, Pietro Monac. LC-MS/MS profiling of a mastic leaf phenol enriched extract and its effects on H2O2 and Aβ(25-35) oxidative injury in SK-B-NE(C)-2 cells. Journal of agricultural and food chemistry. vol 62. issue 49. 2015-07-28. PMID:25405583. |
in order to evaluate the preparation of a safe and no toxic extract, mtt, srb, and ldh assays toward sh-5ysy, and sk-n-be(2)-c human neuronal cell lines, as well as on c6 mouse glial cell line, were performed. |
2015-07-28 |
2023-08-13 |
mouse |
| Jae Hyun Ahn, Ji Won Choi, Ji Myung Choi, Takahiro Maeda, Hajime Fujii, Takako Yokozawa, Eun Ju Ch. Protective role of oligonol from oxidative stress-induced inflammation in C6 glial cell. Nutrition research and practice. vol 9. issue 2. 2015-04-11. PMID:25861417. |
protective role of oligonol from oxidative stress-induced inflammation in c6 glial cell. |
2015-04-11 |
2023-08-13 |
Not clear |
| Annagrazia Adornetto, Valentina Pagliara, Gianfranco Di Renzo, Rosaria Arcon. Polychlorinated biphenyls impair dibutyryl cAMP-induced astrocytic differentiation in rat C6 glial cell line. FEBS open bio. vol 3. 2013-11-19. PMID:24251112. |
polychlorinated biphenyls impair dibutyryl camp-induced astrocytic differentiation in rat c6 glial cell line. |
2013-11-19 |
2023-08-12 |
rat |
| T C Paredes-Santos, E S Martins-Duarte, R W A Vitor, W de Souza, M Attias, R C Vommar. Spontaneous cystogenesis in vitro of a Brazilian strain of Toxoplasma gondii. Parasitology international. vol 62. issue 2. 2013-09-16. PMID:23269201. |
we observed that tachyzoites of the egs strain converted to intracellular cysts spontaneously in llc-mk2 epithelial cells, hsfs fibroblasts and c6 glial cell lineage. |
2013-09-16 |
2023-08-12 |
human |
| Shuken Boku, Shin Nakagawa, Naoki Takamura, Akiko Kato, Minoru Takebayashi, Kazue Hisaoka-Nakashima, Yuki Omiya, Takeshi Inoue, Ichiro Kusum. GDNF facilitates differentiation of the adult dentate gyrus-derived neural precursor cells into astrocytes via STAT3. Biochemical and biophysical research communications. vol 434. issue 4. 2013-08-27. PMID:23603362. |
because previous studies showed that antidepressants increase the expression and secretion of glial cell line-derived neurotrophic factor (gdnf) in c6 glioma cells derived from rat astrocytes and gdnf increases neurogenesis in adult dg in vivo, we investigated the effects of gdnf on the proliferation, differentiation and apoptosis of cultured neural precursor cells derived from the adult dg. |
2013-08-27 |
2023-08-12 |
rat |
| Parichehr Hassanzadeh, Elham Arbab. The Effects of Progesterone on Glial Cell Line-derived Neurotrophic Factor Secretion from C6 Glioma Cells. Iranian journal of basic medical sciences. vol 15. issue 5. 2013-03-18. PMID:23493386. |
the effects of progesterone on glial cell line-derived neurotrophic factor secretion from c6 glioma cells. |
2013-03-18 |
2023-08-12 |
Not clear |
| Yoko Hirata, Kyoji Furuta, Masaaki Suzuki, Kentaro Oh-hashi, Yoshihito Ueno, Kazutoshi Kiuch. Neuroprotective cyclopentenone prostaglandins up-regulate neurotrophic factors in C6 glioma cells. Brain research. vol 1482. 2013-03-12. PMID:22982731. |
in the present study, we showed that these compounds and their lead compound, nepp11, are potent inducers of glial cell line-derived neurotrophic factor (gdnf) expression in c6 glioma cells and primary astrocytes. |
2013-03-12 |
2023-08-12 |
Not clear |
| Iris K Salgado, Melissa Serrano, José O García, Namyr A Martínez, Héctor M Maldonado, Carlos A Báez-Pagán, José A Lasalde-Dominicci, Walter I Silv. SorLA in glia: shared subcellular distribution patterns with caveolin-1. Cellular and molecular neurobiology. vol 32. issue 3. 2012-12-20. PMID:22127416. |
a set of complementary experimental approaches establish that sorla and cav-1 directly or indirectly interact in glia: (1) co-fractionation in light-density membrane raft fractions of rat c6 glioma, pcra, and human 1321n1 astrocytoma cells; (2) a subcellular co-localization distribution pattern in vesicular perinuclear compartments seen via confocal imaging in c6 and pcra; (3) additional confocal analysis in c6 cells suggesting that the perinuclear compartments correspond to their co-localization in early endosomes and the trans-golgi; and; (4) co-immunoprecipitation data strongly supporting their direct or indirect physical interaction. |
2012-12-20 |
2023-08-12 |
human |
| F Maher, T M Davies-Hill, P G Lysko, R C Henneberry, I A Simpso. Expression of two glucose transporters, GLUT1 and GLUT3, in cultured cerebellar neurons: Evidence for neuron-specific expression of GLUT3. Molecular and cellular neurosciences. vol 2. issue 4. 2012-10-02. PMID:19912819. |
significant glut3 expression was also detected in the neuronal cell lines pc12 and ng108 but not in primary cultured glia or c6 glioma cells. |
2012-10-02 |
2023-08-12 |
rat |
| K Okumura-Noji, T Kato, J Ito, R Tanaka, S Wakabayashi, Y Wad. Inhibition by diphenylhydantoin of growth and morphological differentiation of glial cells: Implication of calcium. Neurochemistry international. vol 14. issue 3. 2012-10-02. PMID:20504437. |
the dph inhibition of the dna synthesis was most marked in rat fetal glioblasts induced by glia maturation factor (gmf) among the cell lines studied, and that in c6 cells. |
2012-10-02 |
2023-08-12 |
rat |