| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| B Wiesenhofer, C Weis, C Humpe. Glial cell line-derived neurotrophic factor (GDNF) is a proliferation factor for rat C6 glioma cells: evidence from antisense experiments. Antisense & nucleic acid drug development. vol 10. issue 5. 2001-02-22. PMID:11079571. |
glial cell line-derived neurotrophic factor (gdnf) is a proliferation factor for rat c6 glioma cells: evidence from antisense experiments. |
2001-02-22 |
2023-08-12 |
human |
| B Wiesenhofer, C Weis, C Humpe. Glial cell line-derived neurotrophic factor (GDNF) is a proliferation factor for rat C6 glioma cells: evidence from antisense experiments. Antisense & nucleic acid drug development. vol 10. issue 5. 2001-02-22. PMID:11079571. |
glial cell line-derived neurotrophic factor (gdnf) has been shown recently to be highly expressed in human glioblastomas and in rat glial cell lines b49 and c6. |
2001-02-22 |
2023-08-12 |
human |
| D Vandier, O Rixe, F Besnard, M Kim, T Rikiyama, M Goldsmith, M Brenner, A Gouyette, K H Cowa. Inhibition of glioma cells in vitro and in vivo using a recombinant adenoviral vector containing an astrocyte-specific promoter. Cancer gene therapy. vol 7. issue 8. 2000-12-22. PMID:10975672. |
infection by adgfa2tk of a glial cell line (c6) and a non-glial cell line (mda-mb-231) revealed markedly increased expression of hsv-tk in glial cells as determined by western blot. |
2000-12-22 |
2023-08-12 |
mouse |
| D Vandier, O Rixe, F Besnard, M Kim, T Rikiyama, M Goldsmith, M Brenner, A Gouyette, K H Cowa. Inhibition of glioma cells in vitro and in vivo using a recombinant adenoviral vector containing an astrocyte-specific promoter. Cancer gene therapy. vol 7. issue 8. 2000-12-22. PMID:10975672. |
infection of two glial cell lines (c6, u251) and two non-glial cell lines (hepg2, mda-mb-231) with adgfa2tk followed by gcv treatment revealed high toxicity in glial cell lines (50% growth inhibitory concentration: <2 microg/ml of gcv) with little or no toxicity (50% growth inhibitory concentration: >75 microg/ml) in the non-glial cell lines. |
2000-12-22 |
2023-08-12 |
mouse |
| S Fischer, M Wobben, J Kleinstück, D Renz, W Schape. Effect of astroglial cells on hypoxia-induced permeability in PBMEC cells. American journal of physiology. Cell physiology. vol 279. issue 4. 2000-10-30. PMID:11003573. |
hypoxia-induced hyperpermeability was decreased significantly in a coculture model of astroglia cells, either astrocytes or c6 glioma cells, with pbmec and, to the same extent, when glia cell-conditioned medium was used. |
2000-10-30 |
2023-08-12 |
cattle |
| P Martín-Vasallo, R K Wetzel, L M García-Segura, E Molina-Holgado, E Arystarkhova, K J Sweadne. Oligodendrocytes in brain and optic nerve express the beta3 subunit isoform of Na,K-ATPase. Glia. vol 31. issue 3. 2000-10-16. PMID:10941147. |
since beta3 was not found at detectable levels in astrocytes, this suggests that c6 is closer to oligodendrocytes than astrocytes in the glial cell lineage. |
2000-10-16 |
2023-08-12 |
mouse |
| B Wiesenhofer, C Humpe. Lipid-mediated gene transfer into primary neurons using FuGene: comparison to C6 glioma cells and primary glia. Experimental neurology. vol 164. issue 1. 2000-08-16. PMID:10877913. |
lipid-mediated gene transfer into primary neurons using fugene: comparison to c6 glioma cells and primary glia. |
2000-08-16 |
2023-08-12 |
Not clear |
| B Wiesenhofer, C Humpe. Lipid-mediated gene transfer into primary neurons using FuGene: comparison to C6 glioma cells and primary glia. Experimental neurology. vol 164. issue 1. 2000-08-16. PMID:10877913. |
in this study we investigated the lipid-mediated gene transfer into primary neurons in vitro by using the novel nonliposomal lipid fugene and compared it to primary glia and malignant c6 glioma cells. |
2000-08-16 |
2023-08-12 |
Not clear |
| B Wiesenhofer, C Humpe. Lipid-mediated gene transfer into primary neurons using FuGene: comparison to C6 glioma cells and primary glia. Experimental neurology. vol 164. issue 1. 2000-08-16. PMID:10877913. |
fugene-mediated gene transfer was useful to transfer the reporter gene beta-galactosidase into c6 glioma cells, primary glia, and primary neurons. |
2000-08-16 |
2023-08-12 |
Not clear |
| N J Pantazis, A Zaheer, D Dai, S Zaheer, S H Green, R Li. Transfection of C6 glioma cells with glia maturation factor upregulates brain-derived neurotrophic factor and nerve growth factor: trophic effects and protection against ethanol toxicity in cerebellar granule cells. Brain research. vol 865. issue 1. 2000-07-21. PMID:10814733. |
transfection of c6 glioma cells with glia maturation factor upregulates brain-derived neurotrophic factor and nerve growth factor: trophic effects and protection against ethanol toxicity in cerebellar granule cells. |
2000-07-21 |
2023-08-12 |
Not clear |
| J D Cheng, J de Velli. Oligodendrocytes as glucocorticoids target cells: functional analysis of the glycerol phosphate dehydrogenase gene. Journal of neuroscience research. vol 59. issue 3. 2000-03-16. PMID:10679781. |
the enzyme glycerol phosphate dehydrogenase (e.c.1.1.1.8) has been used as a model to study glucocorticoid regulation of gene expression in oligodendrocytes and the c6 glial cell line. |
2000-03-16 |
2023-08-12 |
mouse |
| J D Cheng, J de Velli. Oligodendrocytes as glucocorticoids target cells: functional analysis of the glycerol phosphate dehydrogenase gene. Journal of neuroscience research. vol 59. issue 3. 2000-03-16. PMID:10679781. |
transient transfection of reporter constructs into the c6 glial cell line revealed that the distal end of the 5' flanking region was glucocorticoid-inducible. |
2000-03-16 |
2023-08-12 |
mouse |
| M S Kobayashi, D Han, L Packe. Antioxidants and herbal extracts protect HT-4 neuronal cells against glutamate-induced cytotoxicity. Free radical research. vol 32. issue 2. 2000-02-11. PMID:10653482. |
we have previously shown that pro-glutathione agents can spare gsh and protect cells from glutamate insult in a c6 glial cell model. |
2000-02-11 |
2023-08-12 |
Not clear |
| R Lim, A Zaheer, M A Yorek, C J Darby, L W Oberle. Activation of nuclear factor-kappaB in C6 rat glioma cells after transfection with glia maturation factor. Journal of neurochemistry. vol 74. issue 2. 2000-02-10. PMID:10646510. |
activation of nuclear factor-kappab in c6 rat glioma cells after transfection with glia maturation factor. |
2000-02-10 |
2023-08-12 |
human |
| R Lim, A Zaheer, M A Yorek, C J Darby, L W Oberle. Activation of nuclear factor-kappaB in C6 rat glioma cells after transfection with glia maturation factor. Journal of neurochemistry. vol 74. issue 2. 2000-02-10. PMID:10646510. |
the 17-kda endogenous brain protein glia maturation factor (gmf) was transfected into c6 rat glioma cells using a replication-defective human adenovirus vector. |
2000-02-10 |
2023-08-12 |
human |
| A Zaheer, J L Weiss, P Goyal, R Li. Enhanced expression of neurotrophic factors by C6 rat glioma cells after transfection with glia maturation factor. Neuroscience letters. vol 265. issue 3. 1999-07-01. PMID:10327166. |
enhanced expression of neurotrophic factors by c6 rat glioma cells after transfection with glia maturation factor. |
1999-07-01 |
2023-08-12 |
rat |
| I Mountain, E Waelkens, L Missiaen, W van Driessch. Changes in actin cytoskeleton during volume regulation in C6 glial cells. European journal of cell biology. vol 77. issue 3. 1999-03-09. PMID:9860135. |
changes in actin cytoskeleton in the c6 rat glial cell line were studied during decrease or increase (abrupt or gradual) of extracellular osmolality. |
1999-03-09 |
2023-08-12 |
rat |
| R Lim, A Zaheer, J A Kraakevik, C J Darby, L W Oberle. Overexpression of glia maturation factor in C6 cells promotes differentiation and activates superoxide dismutase. Neurochemical research. vol 23. issue 11. 1999-03-08. PMID:9814556. |
overexpression of glia maturation factor in c6 cells promotes differentiation and activates superoxide dismutase. |
1999-03-08 |
2023-08-12 |
mouse |
| R Lim, A Zaheer, J A Kraakevik, C J Darby, L W Oberle. Overexpression of glia maturation factor in C6 cells promotes differentiation and activates superoxide dismutase. Neurochemical research. vol 23. issue 11. 1999-03-08. PMID:9814556. |
in order to evaluate the intracellular function of glia maturation factor (gmf), we overexpressed gmf in c6 rat glioma cells using two methods: stable transfection using the pcdna3 plasmid, and transient transfection using replication-defective human adenovirus. |
1999-03-08 |
2023-08-12 |
mouse |
| K Morita, K Ishimura, Y Tsuruo, D L Won. Dexamethasone enhances serum deprivation-induced necrotic death of rat C6 glioma cells through activation of glucocorticoid receptors. Brain research. vol 816. issue 2. 1999-03-04. PMID:9878804. |
the effect of the synthetic glucocorticoid dexamethasone (dex) on glial cell viability was therefore examined by measuring neutral red uptake into rat c6 glioma cells. |
1999-03-04 |
2023-08-12 |
rat |