| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| H Sakai, S Nakashima, S Yoshimura, Y Nishimura, N Sakai, Y Nozaw. Identification of differentially expressed mRNAs during rat C6 glial cell differentiation by mRNA fingerprinting using arbitrarily primed PCR (RAP). Neuroscience letters. vol 229. issue 2. 1997-09-16. PMID:9223599. |
identification of differentially expressed mrnas during rat c6 glial cell differentiation by mrna fingerprinting using arbitrarily primed pcr (rap). |
1997-09-16 |
2023-08-12 |
rat |
| H Sakai, S Nakashima, S Yoshimura, Y Nishimura, N Sakai, Y Nozaw. Identification of differentially expressed mRNAs during rat C6 glial cell differentiation by mRNA fingerprinting using arbitrarily primed PCR (RAP). Neuroscience letters. vol 229. issue 2. 1997-09-16. PMID:9223599. |
to identify differentially expressed genes that are involved in rat c6 glial cell differentiation induced by dibutyryl cyclic amp and theophylline, mrna fingerprinting using arbitrarily primed pcr (rap) was used. |
1997-09-16 |
2023-08-12 |
rat |
| S Yoshimura, H Sakai, S Nakashima, Y Nozawa, J Shinoda, N Sakai, H Yamad. Differential expression of Rho family GTP-binding proteins and protein kinase C isozymes during C6 glial cell differentiation. Brain research. Molecular brain research. vol 45. issue 1. 1997-08-27. PMID:9105674. |
differential expression of rho family gtp-binding proteins and protein kinase c isozymes during c6 glial cell differentiation. |
1997-08-27 |
2023-08-12 |
rat |
| M S Feschenko, K J Sweadne. Phosphorylation of Na,K-ATPase by protein kinase C at Ser18 occurs in intact cells but does not result in direct inhibition of ATP hydrolysis. The Journal of biological chemistry. vol 272. issue 28. 1997-08-14. PMID:9211924. |
the cells used were derived from rat (nrk 52e, c6, l6, and primary cultures of cerebellar granule cells, representing epithelial cells, glia, muscle cells, and neurons). |
1997-08-14 |
2023-08-12 |
rat |
| C Brodie, N Weizman, A Katzoff, S Lustig, D Kobile. Astrocyte activation by Sindbis virus: expression of GFAP, cytokines, and adhesion molecules. Glia. vol 19. issue 4. 1997-07-24. PMID:9097072. |
in this study we compared the effects of two strains of sv, sva, and svni, which differ in their neurovirulent properties, on astrocytes with the use of cultured mouse astrocytes and the rat c6 glial cell line. |
1997-07-24 |
2023-08-12 |
mouse |
| A Wu, M N Pangalos, S Efthimiopoulos, J Shioi, N K Robaki. Appican expression induces morphological changes in C6 glioma cells and promotes adhesion of neural cells to the extracellular matrix. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 17. issue 13. 1997-07-17. PMID:9185536. |
under the same conditions, however, <20% of the appican-transfected c6 cells were dissociated from their substrate, suggesting that the appican-transfected glia cells attach more avidly to their substrate than do untransfected or app transfected control cells. |
1997-07-17 |
2023-08-12 |
rat |
| L Goya, P T Feng, S Aliabadi, P S Timira. Effect of growth factors on the in vitro growth and differentiation of early and late passage C6 glioma cells. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 14. issue 4. 1997-01-24. PMID:8884374. |
these results further present the c6 glioma cell line as a useful model for studies on glial cell properties and responsiveness in culture and support its use in experimental aging in vitro. |
1997-01-24 |
2023-08-12 |
rat |
| N Serkova, A Brand, U Christians, D Leibfrit. Evaluation of the effects of immunosuppressants on neuronal and glial cells in vitro by multinuclear magnetic resonance spectroscopy. Biochimica et biophysica acta. vol 1314. issue 1-2. 1997-01-22. PMID:8972722. |
changes in the cellular metabolism of glial cells (c6 rat glioma), neuronal cells (n1e-115 mouse neuroblastoma) and primary glia cells (isolated from rats) after addition of cyclosporine and tacrolimus were investigated using 1h-, 13c- and 31p-nmr spectroscopy in vitro. |
1997-01-22 |
2023-08-12 |
mouse |
| J A Payne, T J Stevenson, L F Donaldso. Molecular characterization of a putative K-Cl cotransporter in rat brain. A neuronal-specific isoform. The Journal of biological chemistry. vol 271. issue 27. 1996-08-29. PMID:8663311. |
reverse transcriptase-polymerase chain reaction revealed that kcc1 was present in rat primary astrocytes and rat c6 glioma cells but that kcc2 was completely absent from these cells, suggesting kcc2 was not of glial cell origin. |
1996-08-29 |
2023-08-12 |
rat |
| D C Crick, C J Waechter, D A Andre. Geranylgeraniol restores cell proliferation to lovastatin treated C6 glial cells. SAAS bulletin, biochemistry and biotechnology. vol 9. 1996-07-30. PMID:8652130. |
since we have previously shown that farnesol (f-oh) and geranylgeraniol (gg-oh) can be utilized for protein isoprenylation, the ability of the free allylic isoprenols to overcome the lovastatin-induced block on rat c6 glial cell proliferation has been investigated. |
1996-07-30 |
2023-08-12 |
rat |
| S K Han, C Mytilineou, G Cohe. L-DOPA up-regulates glutathione and protects mesencephalic cultures against oxidative stress. Journal of neurochemistry. vol 66. issue 2. 1996-04-03. PMID:8592119. |
incubation with l-dopa induced a rise in gsh level in cultures of fetal rat mesencephalon, mouse neuroblastoma (neuro-2a), human neuroblastoma (sk-n-mc), pig kidney epithelial cells (llc-pk1), and glia from newborn rat brain, but not c6 glioma cells or neuronal cultures (no glia) from the mesencephalon. |
1996-04-03 |
2023-08-12 |
mouse |
| T Brisma. Physiology of transformed glial cells. Glia. vol 15. issue 3. 1996-03-27. PMID:8586460. |
much of our present knowledge of glial cell function stems from studies of glioma cell lines, both rodent (c6, c6 polyploid, and tr33b) and human (1321n1, 138mg, d384, r-111, t67, tp-276mg, tp-301mg, tp-483mg, tp-387mg, u-118mg, u-251mg, u-373mg, u-787mg, u-1242mg, and uc-11mg). |
1996-03-27 |
2023-08-12 |
human |
| A Zaheer, W Zhong, E Y Uc, D R Moser, R Li. Expression of mRNAs of multiple growth factors and receptors by astrocytes and glioma cells: detection with reverse transcription-polymerase chain reaction. Cellular and molecular neurobiology. vol 15. issue 2. 1996-03-25. PMID:8590453. |
to present a unified picture of the growth factors and their receptors found in glial cells, we surveyed the expression of messenger rnas of a panel of growth factors and receptors, using reverse transcription-polymerase chain reaction (rt-pcr), in three common glial cell types: rat astrocytes in primary culture, rat glioma line c6, and human glioma line a172. |
1996-03-25 |
2023-08-12 |
human |
| T Iwaki, A Iwaki, Y Fukumaki, J Tateish. Alpha B-crystallin in C6 glioma cells supports their survival in elevated extracellular K+: the implication of a protective role of alpha B-crystallin accumulation in reactive glia. Brain research. vol 673. issue 1. 1995-06-28. PMID:7757478. |
alpha b-crystallin in c6 glioma cells supports their survival in elevated extracellular k+: the implication of a protective role of alpha b-crystallin accumulation in reactive glia. |
1995-06-28 |
2023-08-12 |
rat |
| P A Grabb, M R Gilber. Neoplastic and pharmacological influence on the permeability of an in vitro blood-brain barrier. Journal of neurosurgery. vol 82. issue 6. 1995-06-27. PMID:7760177. |
these in vitro bbb experiments showed that: 1) malignant glia, such as 9l and t98g cells, increase pe whereas c6 cells probably provide an astrocytic influence by reducing pe; 2) dexamethasone provided significant bbb "tightening" effects both in the presence and absence of glioma cells; 3) the in vivo bbb is actively made more permeable by malignant glia and not simply because of a lack of astrocytic induction; 4) tumor or endothelial phospholipase a2 activity is probably not responsible for glioma-induced increased in bbb permeability; and 5) this model is useful for testing potential agents for bbb protection and for studying the pathophysiology of tumor-induced bbb disruption. |
1995-06-27 |
2023-08-12 |
human |
| D M Bagaglio, W N Hai. Role of calmodulin-dependent phosphorylation of elongation factor 2 in the proliferation of rat glial cells. Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research. vol 5. issue 12. 1995-05-03. PMID:7696190. |
previously, we have shown that cam-dependent protein kinase iii phosphorylates elongation factor 2 (ef-2) in proliferating, c6 glioma cells but not in normal white matter, a tissue rich in nonproliferating glia. |
1995-05-03 |
2023-08-12 |
rat |
| D M Bagaglio, W N Hai. Role of calmodulin-dependent phosphorylation of elongation factor 2 in the proliferation of rat glial cells. Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research. vol 5. issue 12. 1995-05-03. PMID:7696190. |
to determine whether cam-dependent phosphorylation of ef-2 is linked, in general, to cellular division, we studied the phosphorylation of ef-2 in proliferating and growth-arrested c6 cells and in proliferating, primary cultures of normal glia. |
1995-05-03 |
2023-08-12 |
rat |
| L D Shrode, R W Putna. Intracellular pH regulation in primary rat astrocytes and C6 glioma cells. Glia. vol 12. issue 3. 1995-03-14. PMID:7851988. |
since c6 cells lack the na(+)-hco3- cotransporter, they are an inferior model of phi regulation in glia. |
1995-03-14 |
2023-08-12 |
rat |
| J Segovia, G M Lawless, N J Tillakaratne, M Brenner, A J Tobi. Cyclic AMP decreases the expression of a neuronal marker (GAD67) and increases the expression of an astroglial marker (GFAP) in C6 cells. Journal of neurochemistry. vol 63. issue 4. 1994-11-01. PMID:7931275. |
c6 cells express proteins and mrnas that are characteristic of both glia and neurons. |
1994-11-01 |
2023-08-12 |
human |
| T G Hales, R F Tyndal. Few cell lines with GABAA mRNAs have functional receptors. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 14. issue 9. 1994-10-12. PMID:8083746. |
in the preceding companion article (tyndale et al., 1994) we used the pcr to investigate the occurrence of 13 gabaa receptor subunit mrnas in several cell lines, including those derived from brain (b65, b104, and nb41a3), cerebellum (c17), glia (c6), pituitary (att-20), adrenal medulla (pc12), and the endocrine pancreas (rinm5f and beta tc3). |
1994-10-12 |
2023-08-12 |
Not clear |