| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Qiujin Qian, Yufeng Wang, Jun Li, Li Yang, Bing Wang, Rulun Zhou, Stephen J Glatt, Stephen V Faraon. Evaluation of potential gene-gene interactions for attention deficit hyperactivity disorder in the Han Chinese population. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 144B. issue 2. 2007-04-11. PMID:17044099. |
to explore potential gene-gene interactions among candidate genes for adhd, we studied the dopamine d2 receptor (drd2), dopamine d4 receptor (drd4), dopamine transporter (dat1), and catechol-o-methyltransferase (comt) genes in the han chinese population. |
2007-04-11 |
2023-08-12 |
Not clear |
| Agnieszka Słopién, Monika Dmitrzak-Weglarz, Filip Rybakowski, Andrzej Rajewski, Joanna Hause. [Genetic background of ADHD: population studies, genes of the catecholamine system]. Psychiatria polska. vol 40. issue 1. 2007-03-20. PMID:16756025. |
according to other studies there is a relationship between polymorphism of dopamine transporter gene (dat), dopamine receptors genes: drd2, drd3, drd4, drd5, dopamine-beta-hydroxylase gene (dbh) and catechol-o-methyltransferase gene (comt) and adhd. |
2007-03-20 |
2023-08-12 |
Not clear |
| Ulrich Ettinger, Ridha Joober, Rosherrie DE Guzman, Gillian A O'driscol. Schizotypy, attention deficit hyperactivity disorder, and dopamine genes. Psychiatry and clinical neurosciences. vol 60. issue 6. 2007-01-23. PMID:17109713. |
catechol-o-methyltransferase (comt) val158met, dopamine receptors of the d3 type (drd3) ser9gly, drd4 variable number of tandem repeats (vntr), and slc6a3 vntr polymorphisms were analyzed. |
2007-01-23 |
2023-08-12 |
Not clear |
| V E Golimbet, M V Alfimova, I K Gritsenko, R P Ebshteĭ. [Dopamine system genes and personality traits of extraversion and novelty seeking]. Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova. vol 56. issue 4. 2006-11-03. PMID:17025189. |
the study was aimed at a search for association of catechol-o-metyltransferase (comt) and dopamine receptor d4 (drd4) gene polymorphism with personality traits in russian population. |
2006-11-03 |
2023-08-12 |
human |
| M V Alfimova, V E Golimbet, I K Gritsenko, T V Lezheĭko, L I Abramova, M A Strel'tsova, I V Khlopina, R Ebstei. [Dopamine system genes interaction and neurocognitive traits in patients with schizophrenia, their relatives and healthy controls from general population]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. vol 106. issue 7. 2006-09-14. PMID:16921721. |
to elucidate main effects of dopamine receptor d4 (drd4) and cathecol-o-methyltransferase (comt) genes as well as their interaction effect on neurocognitive traits, drd4 gene polymorphisms (-809g/a, -521c/t) and the comt gene val158met polymorphism, along with characteristics of verbal memory, executive functions and peculiarities of associative processes, have been studied in 150 patients with schizophrenia, 83 their relatives and 118 mentally healthy subjects without positive family history of psychosis. |
2006-09-14 |
2023-08-12 |
human |
| M V Alfimova, V E Golimbet, I K Gritsenko, T V Lezheĭko, L I Abramova, M A Strel'tsova, I V Khlopina, R Ebstei. [Dopamine system genes interaction and neurocognitive traits in patients with schizophrenia, their relatives and healthy controls from general population]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. vol 106. issue 7. 2006-09-14. PMID:16921721. |
the data obtained suggest the relationship of drd4 and comt genes with different characteristics of executive functions but not with verbal memory. |
2006-09-14 |
2023-08-12 |
human |
| S Cevoli, M Mochi, C Scapoli, N Marzocchi, G Pierangeli, L A Pini, P Cortelli, P Montagn. A genetic association study of dopamine metabolism-related genes and chronic headache with drug abuse. European journal of neurology. vol 13. issue 9. 2006-09-11. PMID:16930369. |
we performed a genetic association study using four functional polymorphisms of the dopamine receptor 4 (drd4), dopamine transporter (dat), mono-amino-oxidase a (maoa) and cathecol-o-methyl-transferase (comt) genes in 103 patients with chronic daily headache associated with da (cdhda). |
2006-09-11 |
2023-08-12 |
Not clear |
| V E Golimbet, I S Lebedeva, I K Gritsenko, G I Korovaĭtseva, M V Alfimova, T V Lezheĭko, L I Abramova, V G Kaleda, R P Ebshteĭn, E I Rogae. [A study of some genes related to serotoninergic and dopaminergic systems and auditory evoked-potentials (P300) in patients with schizophrenia and spectrum disorders and their first-degree relatives]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. vol 105. issue 10. 2006-01-04. PMID:16281377. |
we studied p300 parameters and the following polymorphisms: t102c for the serotonin receptor type 2a (5-htr2a) gene, the 5-httlpr for the serotonin transporter gene, -809g/a, -616g/c n -52c/t snps in the promoter region of the dopamine d4 receptor (drd4) gene and the val158met polymorphism of the catechol-o-methyltransferase (comt) in 74 patients with schizophrenia and spectrum disorders and 71 their first-degree relatives. |
2006-01-04 |
2023-08-12 |
human |
| Hamid M Abdolmaleky, Sam Thiagalingam, Marsha Wilco. Genetics and epigenetics in major psychiatric disorders: dilemmas, achievements, applications, and future scope. American journal of pharmacogenomics : genomics-related research in drug development and clinical practice. vol 5. issue 3. 2005-09-29. PMID:15952869. |
for example, several genes including those encoding dopamine receptors (drd2, drd3, and drd4), serotonin receptor 2a (htr2a) and catechol-o-methyltransferase (comt) have been implicated in the etiology of schizophrenia and related disorders through meta-analyses and large, multicenter studies. |
2005-09-29 |
2023-08-12 |
Not clear |
| James J McGoug. Attention-deficit/hyperactivity disorder pharmacogenomics. Biological psychiatry. vol 57. issue 11. 2005-07-29. PMID:15950009. |
other candidates include drd4, drd5, dbh, 5htt, snap-25, and comt. |
2005-07-29 |
2023-08-12 |
human |
| Aaron J Bobb, Anjene M Addington, Ellen Sidransky, Michele C Gornick, Jason P Lerch, Deanna K Greenstein, Liv S Clasen, Wendy S Sharp, Gale Inoff-Germain, Fabienne Wavrant-De Vrièze, Mauricio Arcos-Burgos, Richard E Straub, John A Hardy, F Xavier Castellanos, Judith L Rapopor. Support for association between ADHD and two candidate genes: NET1 and DRD1. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 134B. issue 1. 2005-05-09. PMID:15717291. |
dna from 163 adhd probands, 192 parents, and 129 healthy controls was used to investigate possible associations between adhd and polymorphisms in 12 previously studied candidate genes (5-ht1b, 5-ht2a, 5-ht2c, adra2a, chrna4, comt, dat1, drd1, drd4, drd5, net1, and snap-25). |
2005-05-09 |
2023-08-12 |
mouse |
| Philip Seeman, David Weinshenker, Remi Quirion, Lalit K Srivastava, Sanjeev K Bhardwaj, David K Grandy, Richard T Premont, Tatyana D Sotnikova, Patricia Boksa, Mufida El-Ghundi, Brian F O'dowd, Susan R George, Melissa L Perreault, Pekka T Männistö, Siobhan Robinson, Richard D Palmiter, Teresa Talleric. Dopamine supersensitivity correlates with D2High states, implying many paths to psychosis. Proceedings of the National Academy of Sciences of the United States of America. vol 102. issue 9. 2005-04-13. PMID:15716360. |
dopamine supersensitivity occurs in schizophrenia and other psychoses, and after hippocampal lesions, antipsychotics, ethanol, amphetamine, phencyclidine, gene knockouts of dbh (dopamine beta-hydroxylase), drd4 receptors, gprk6 (g protein-coupled receptor kinase 6), comt (catechol-o-methyltransferase), or th-/-, dbhth/+ (tyrosine hydroxylase), and in rats born by cesarean-section. |
2005-04-13 |
2023-08-12 |
rat |
| A Strobel, K P Lesch, S Jatzke, F Paetzold, B Brock. Further evidence for a modulation of Novelty Seeking by DRD4 exon III, 5-HTTLPR, and COMT val/met variants. Molecular psychiatry. vol 8. issue 4. 2004-02-20. PMID:12740593. |
further evidence for a modulation of novelty seeking by drd4 exon iii, 5-httlpr, and comt val/met variants. |
2004-02-20 |
2023-08-12 |
Not clear |
| Ming-lian Zhang, Guo-zhen Yuan, Jian-jun Yao, Yong-chao Qian, Xia Zhang, Yin-ping Huang, Rui-chun Tang, Qing Ji, San-duo Jian. [Associations between six functional genes and schizophrenia]. Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics. vol 20. issue 1. 2003-09-02. PMID:12579508. |
to assess the associations between schizophrenia and six functional genes: dopamine d2 receptor gene (drd2), dopamine d4 receptor gene (drd4), 5-hydroxytryptamine 2a receptor gene (5-ht2a), 5-ht6 receptor gene (5-ht6), catechol-o-methyltransferase gene (comt) and dopamine transporter gene (dat1). |
2003-09-02 |
2023-08-12 |
Not clear |
| Shoshana Arbelle, Jonathan Benjamin, Moshe Golin, Ilana Kremer, Robert H Belmaker, Richard P Ebstei. Relation of shyness in grade school children to the genotype for the long form of the serotonin transporter promoter region polymorphism. The American journal of psychiatry. vol 160. issue 4. 2003-05-20. PMID:12668354. |
toward further elucidating the genetic structure of shyness, the authors examined four functional polymorphisms that make biological sense for contributing to the development of this phenotype: serotonin transporter promoter region 44 base pair insertion/deletion (5-httlpr), dopamine d(4) receptor exon iii repeat (drd4), catechol o-methyltransferase (comt), and monoamine oxidase a promoter region repeat (mao(a)). |
2003-05-20 |
2023-08-12 |
Not clear |
| Cristina Cusin, Alessandro Serretti, Enrico Lattuada, Roberta Lilli, Cristina Lorenzi, Enrico Smerald. Association study of MAO-A, COMT, 5-HT2A, DRD2, and DRD4 polymorphisms with illness time course in mood disorders. American journal of medical genetics. vol 114. issue 4. 2002-09-27. PMID:11992560. |
association study of mao-a, comt, 5-ht2a, drd2, and drd4 polymorphisms with illness time course in mood disorders. |
2002-09-27 |
2023-08-12 |
human |
| Cristina Cusin, Alessandro Serretti, Enrico Lattuada, Roberta Lilli, Cristina Lorenzi, Enrico Smerald. Association study of MAO-A, COMT, 5-HT2A, DRD2, and DRD4 polymorphisms with illness time course in mood disorders. American journal of medical genetics. vol 114. issue 4. 2002-09-27. PMID:11992560. |
the aim of our study was to investigate a possible influence of monoamine oxydase a (mao-a), catechol-o-methyltransferase (comt), serotonin receptor 2a (5-ht2a), dopamine receptor d2 (drd2), and dopamine receptor d4 (drd4) gene variants on timing of recurrence in mood disorders. |
2002-09-27 |
2023-08-12 |
human |
| Cristina Cusin, Alessandro Serretti, Enrico Lattuada, Roberta Lilli, Cristina Lorenzi, Enrico Smerald. Association study of MAO-A, COMT, 5-HT2A, DRD2, and DRD4 polymorphisms with illness time course in mood disorders. American journal of medical genetics. vol 114. issue 4. 2002-09-27. PMID:11992560. |
our results suggest that mao-a, comt, 5-ht2a, drd2, and drd4 gene variants are not involved in susceptibility toward different time courses in mood disorders. |
2002-09-27 |
2023-08-12 |
human |
| D E Coming. Clinical and molecular genetics of ADHD and Tourette syndrome. Two related polygenic disorders. Annals of the New York Academy of Sciences. vol 931. 2001-09-06. PMID:11462757. |
some of the specific loci involved are dopamine genes--drd2, drd4, drd5, and the dopamine transporter; norepinephrine (ne) and epinephrine (epi) genes--dopamine beta-hydroxylase, adra2a, adra2c, pnmt, norepinephrine transporter, maoa, comt; serotonin genes--tdo2, htr1a, htr1da, serotonin transporter; gaba genes--gabrb3; androgen receptor and other genes. |
2001-09-06 |
2023-08-12 |
mouse |
| A Payton, J Holmes, J H Barrett, T Hever, H Fitzpatrick, A L Trumper, R Harrington, P McGuffin, M O'Donovan, M Owen, W Ollier, J Worthington, A Thapa. Examining for association between candidate gene polymorphisms in the dopamine pathway and attention-deficit hyperactivity disorder: a family-based study. American journal of medical genetics. vol 105. issue 5. 2001-08-16. PMID:11449400. |
we tested polymorphisms in genes encoding three dopamine receptors (drd3, drd4, and drd5) and four dopamine-relevant enzymes: tyrosine hydroxylase [tyrosine hydroxylase (th)], dopamine beta hydroxylase (dbetah), catechol-o-methyltransferase (comt), and monoamine oxidase a (maoa). |
2001-08-16 |
2023-08-12 |
Not clear |