| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| He Huang, Ning Wang, Jia-Tao Lin, Yong-Kang Qiu, Wei-Feng Wu, Qiang Liu, Chen Chen, Hai-Bi Wang, Yan-Ping Liu, Wei Dong, Jie Wan, Hui Zheng, Cheng-Hua Zhou, Yu-Qing W. Repeated Ketamine Anesthesia during the Neonatal Period Impairs Hippocampal Neurogenesis and Long-Term Neurocognitive Function by Inhibiting Mfn2-Mediated Mitochondrial Fusion in Neural Stem Cells. Molecular neurobiology. 2024-01-10. PMID:38200350. |
for the interventional study, lentivirus (lv) overexpressing mfn2 (lv-mfn2) or control lv vehicle was microinjected into the hippocampal dentate gyrus (dg) 4 days before ketamine administration. |
2024-01-10 |
2024-01-13 |
rat |
| Shahab Ghaderi, Parsa Gholipour, Alireza Komaki, Siamak Shahidi, Faezeh Seif, Mohammad Bahrami-Tapehebur, Iraj Salehi, Mohammad Zarei, Abdolrahman Sarihi, Masome Rashn. Underlying mechanisms behind the neuroprotective effect of vanillic acid against diabetes-associated cognitive decline: An in vivo study in a rat model. Phytotherapy research : PTR. 2024-01-08. PMID:38185917. |
long-term potentiation (ltp) was induced at hippocampal dentate gyrus (dg) synapses in response to high-frequency stimulation (hfs) applied to the perforant pathway (pp) to evaluate synaptic plasticity. |
2024-01-08 |
2024-01-10 |
rat |
| Xiao-Hong Su, Wei-Peng Li, Yi-Jie Wang, Jia Liu, Jun-Yu Liu, Ying Jiang, Fu-Hua Pen. Chronic Administration of 13-cis-retinoic Acid Induces Depression-Like Behavior by Altering the Activity of Dentate Granule Cells. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. vol 19. issue 1. 2024-01-04. PMID:38176807. |
we next demonstrated that chronic 13-cis-ra application increased neural activity in the dentate gyrus (dg) using c-fos immunostaining, which may be critically involved in some aspects of depression-like behavior. |
2024-01-04 |
2024-01-07 |
mouse |
| Nicholas Chalmers, Evangelia Masouti, Ruth Beckervordersandfort. Astrocytes in the adult dentate gyrus-balance between adult and developmental tasks. Molecular psychiatry. 2024-01-04. PMID:38177351. |
in this review, we focus on astrocytes of the hippocampal dentate gyrus (dg), and discuss specific features of the astrocytic compartment that may allow the execution of both tasks. |
2024-01-04 |
2024-01-07 |
Not clear |
| Oier Pastor-Alonso, Anum Syeda Zahra, Bente Kaske, Fernando García-Moreno, Felix Tetzlaff, Enno Bockelmann, Vanessa Grunwald, Soraya Martín-Suárez, Kristoffer Riecken, Otto Wilhelm Witte, Juan Manuel Encinas, Anja Urbac. Generation of adult hippocampal neural stem cells occurs in the early postnatal dentate gyrus and depends on cyclin D2. The EMBO journal. 2024-01-04. PMID:38177500. |
lifelong hippocampal neurogenesis is maintained by a pool of multipotent adult neural stem cells (anscs) residing in the subgranular zone of the dentate gyrus (dg). |
2024-01-04 |
2024-01-07 |
mouse |
| Rong-Xin Zou, Xiaozhen Gu, Chenqing Huang, Hui-Li Wang, Xiang-Tao Che. Chronic Pb exposure impairs learning and memory abilities by inhibiting excitatory projection neuro-circuit of the hippocampus in mice. Toxicology. 2023-12-31. PMID:38160928. |
the virus tracing results revealed that the entorhinal cortex (ec) neurons could be directly projected to cornuammonis 1 (ca1) and dentate gyrus (dg), forming a critical circuit inhibited, in either a direct or indirect way, by pb invasion. |
2023-12-31 |
2024-01-05 |
mouse |
| Dipan C Patel, Nathaniel Swift, Bhanu P Tewari, Jack L Browning, Courtney Prim, Lata Chaunsali, Ian F Kimbrough, Michelle L Olsen, Harald Sontheime. Increased expression of chondroitin sulfate proteoglycans in dentate gyrus and amygdala causes postinfectious seizures. Brain : a journal of neurology. 2023-12-26. PMID:38146224. |
using theiler's murine encephalomyelitis virus (tmev) infection-induced model of acquired epilepsy, we find de novo expression of chondroitin sulfate proteoglycans (cspgs), a major ecm component, in dentate gyrus (dg) and amygdala exclusively in mice with acute seizures. |
2023-12-26 |
2023-12-28 |
mouse |
| Kim Ngan Hoang, Yushan Huang, Esther Fujiwara, Nikolai Malykhi. Effects of healthy aging and mnemonic strategies on verbal memory performance across the adult lifespan: Mediating role of posterior hippocampus. Hippocampus. 2023-12-25. PMID:38145465. |
in this study, we aimed to understand the contributions of hippocampal anteroposterior subregions (head, body, tail) and subfields (cornu ammonis 1-3 [ca1-3], dentate gyrus [dg], and subiculum [sub]) and encoding strategies to the age-related verbal memory decline. |
2023-12-25 |
2023-12-27 |
human |
| b' Andrijana Stanisavljevi\\xc4\\x87 Ili\\xc4\\x87, Sne\\xc5\\xbeana \\xc4\\x90or\\xc4\\x91evi\\xc4\\x87, Drago\\xc5\\xa1 Inta, Stefan Borgwardt, Dragana Filipovi\\xc4\\x8. Olanzapine Effects on Parvalbumin/GAD67 Cell Numbers in Layers/Subregions of Dorsal Hippocampus of Chronically Socially Isolated Rats. International journal of molecular sciences. vol 24. issue 24. 2023-12-23. PMID:38139008.' |
we determined the effect of olz on pv-positive (+) and glutamate decarboxylase 67 (gad67) + cell numbers in the layers of dorsal hippocampus (dhipp) cornu ammonis (ca1-ca3) and dentate gyrus (dg) subregions in rats exposed to chronic social isolation (csis), which is an animal model of depression. |
2023-12-23 |
2023-12-25 |
rat |
| Jasmin A Strickland, Joseph M Austen, Rolf Sprengel, David J Sanderso. Knockout of NMDARs in CA1 and dentate gyrus fails to impair temporal control of conditioned behavior in mice. Hippocampus. 2023-12-23. PMID:38140716. |
we tested the prediction that hippocampal nmda receptors are required for learning about time by testing mice that lack postembryonal nmdars in the ca1 and dentate gyrus (dg) hippocampal subfields on three different appetitive temporal learning procedures. |
2023-12-23 |
2023-12-25 |
mouse |
| Meng Jia, Xi Guo, Ru Liu, Lei Sun, Qun Wang, Jianping W. Overexpress miR-132 in the Brain Parenchyma by a Non-invasive Way Improves Tissue Repairment and Releases Memory Impairment After Traumatic Brain Injury. Cellular and molecular neurobiology. vol 44. issue 1. 2023-12-19. PMID:38104297. |
we found that mir-132 overexpression could reduce impact volume, promote neurogenesis in the dentate gyrus (dg), accelerate neuroblast migrating into the impact cortex, ameliorate microglia-mediated inflammatory reaction, and ultimately restore learning memory function. |
2023-12-19 |
2023-12-21 |
Not clear |
| Rui Yao, Yuanyuan Man, Yao Lu, Yang Su, Meiyan Zhou, Shuang Wang, Xiaoping Gu, Rongguo Wang, Yuqing Wu, Liwei Wan. Infliximab alleviates memory impairment in rats with chronic pain by suppressing neuroinflammation and restoring hippocampal neurogenesis. Neuropharmacology. 2023-12-18. PMID:38110173. |
furthermore, infliximab reversed the decrease in the numbers of newborn neurons and mature neurons in the dentate gyrus (dg) caused by chronic pain. |
2023-12-18 |
2023-12-21 |
rat |
| Hirofumi Hirakawa, Takeshi Terao, Koji Hatano, Masanao Shirahama, Tsuyoshi Kugimiya, Kentaro Kohno, Hiroyuki Matsuta, Tsuyoshi Shimomura, Minoru Fujik. Increased volume of the left hippocampal dentate gyrus after 4 weeks of bright light exposure in patients with mood disorders: a randomized controlled study. Translational psychiatry. vol 13. issue 1. 2023-12-15. PMID:38102115. |
bright light exposure (bl) induces neurogenesis in the rat hippocampal dentate gyrus (dg). |
2023-12-15 |
2023-12-18 |
human |
| Su-Hyun Kim, Chong-Hyun Ki. Neuronal IGF-1 overexpression restores hippocampal newborn cell survival and recent CFC memory consolidation in Ca Brain research. 2023-12-14. PMID:38097125. |
neuronal igf-1 overexpression restores hippocampal newborn cell survival and recent cfc memory consolidation in ca insulin-like growth factor-1 (igf-1) exogenously supplied in the brain was shown to enhance the survival of hippocampal dentate gyrus (dg) newborn cells and some cognitive functions of mice. |
2023-12-14 |
2023-12-17 |
mouse |
| Gayane Grigoryan, Harumi Harada, H Sophie Knobloch-Bollmann, Antje Kilias, Dorthe Kaufhold, Akos Kulik, Mark D Eyre, Marlene Barto. Synaptic plasticity at the dentate gyrus granule cell to somatostatin-expressing interneuron synapses supports object location memory. Proceedings of the National Academy of Sciences of the United States of America. vol 120. issue 51. 2023-12-13. PMID:38091292. |
somatostatin-expressing interneurons (somis) in the mouse dentate gyrus (dg) receive feedforward excitation from granule cell (gc) mossy fiber (mf) synapses and provide feedback lateral inhibition onto gc dendrites to support environment representation in the dg network. |
2023-12-13 |
2023-12-17 |
mouse |
| Yan Luo, Yan Wang, Feng Qiu, Guanghan Hou, Jian Liu, Hui Yang, Mei Wu, Xuanqi Dong, Dongwei Guo, Ziyan Zhong, Xi Zhang, Jinwen Ge, Pan Men. Ablated Sonic Hedgehog Signaling in the Dentate Gyrus of the Dorsal and Ventral Hippocampus Impairs Hippocampal-Dependent Memory Tasks and Emotion in a Rat Model of Depression. Molecular neurobiology. 2023-12-12. PMID:38087166. |
additionally, shh knockdown in the dorsal or ventral dentate gyrus (dg) resulted in restrained neurogenic activity in newborn neurons, especially in immature neurons through decreased expression of shh signaling markers. |
2023-12-12 |
2023-12-17 |
rat |
| Kaige Liu, Yue Qu, Bozhi Li, Ningxi Zeng, Gaolei Yao, Xiaofeng Wu, Hanfang Xu, Can Yan, Lili W. GRP94 in cerebrospinal fluid may contribute to a potential biomarker of depression: Based on proteomics. Journal of psychiatric research. vol 169. 2023-12-11. PMID:38081093. |
flx significantly increased neuronal numbers in dentate gyrus (dg) and ca3 regions of hippocampus. |
2023-12-11 |
2023-12-17 |
rat |
| Michelle C Gulfo, Joseph J Lebowitz, Czarina Ramos, Dong-Woo Hwang, Kaoutsar Nasrallah, Pablo E Castill. Dopamine D2 receptors in hilar mossy cells regulate excitatory transmission and hippocampal function. Proceedings of the National Academy of Sciences of the United States of America. vol 120. issue 50. 2023-12-08. PMID:38064513. |
hilar mossy cells (mcs) are principal excitatory neurons of the dentate gyrus (dg) that play critical roles in hippocampal function and have been implicated in brain disorders such as anxiety and epilepsy. |
2023-12-08 |
2023-12-17 |
Not clear |
| Yu Dong, Zihan Lu, Tiantian Gao, Zhifeng Wei, Zhijie Ou, Zheng Shi, Jie She. A polypeptide derived from pilose antler ameliorates CUMS-induced depression-like behavior by SENP2-PLCβ4 signaling axis. European journal of pharmacology. 2023-12-06. PMID:38056617. |
neurogenesis in the dentate gyrus (dg) region of hippocampus was observed by immunofluorescence. |
2023-12-06 |
2023-12-10 |
Not clear |
| Hongyu Zhao, Arjan Blokland, Jos Prickaerts, Robbert Havekes, Pim R A Heckma. Treatment with the selective PDE4B inhibitor A-33 or PDE4D inhibitor zatolmilast prevents sleep deprivation-induced deficits in spatial pattern separation. Behavioural brain research. 2023-12-06. PMID:38056709. |
sleep deprivation (sd) disrupts hippocampus-dependent memory, particularly in the dentate gyrus (dg) region, an area crucial for pattern separation. |
2023-12-06 |
2023-12-10 |
mouse |