| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Nerina M Villalba, Catalina Madarnas, Julieta Bressano, Viviana Sanchez, Alicia Brusc. Perinatal ethanol exposure affects cell populations in adult dorsal hippocampal neurogenic niche. Neuroscience research. 2023-07-07. PMID:37419388. |
in the adult brain, neurogenesis takes place in the dentate gyrus (dg) of the hippocampus and in the subventricular zone. |
2023-07-07 |
2023-08-14 |
mouse |
| Rafael de Jesús Macias-Velez, Martha Catalina Rivera-Cervantes, Alejandra Guadalupe Marín-López, Justo Murguía-Castill. Intranasal erythropoietin protects granular cells and reduces astrogliosis in the dentate gyrus after ischemic damage, an effect associated with molecular changes in erythropoietin and its receptor. Neuroscience letters. 2023-07-01. PMID:37393008. |
within the hippocampus, the ca1 and dentate gyrus (dg) regions are considered the most and the least susceptible to damage by cerebral ischemia, respectively. |
2023-07-01 |
2023-08-14 |
Not clear |
| Milenna T van Dijk, Ardesheer Talati, Pratik Kashyap, Karan Desai, Nora Kelsall, Marc Gameroff, Natalie Aw, Eyal Abraham, Breda Cullen, Jiook Cha, Christoph Anacker, Myrna M Weissman, Jonathan Posne. Dentate Gyrus Microstructure is associated with Resilience after Exposure to Maternal Stress Across Two Human Cohorts. Biological psychiatry. 2023-07-01. PMID:37393047. |
rodent models implicate the dentate gyrus (dg) of the hippocampus in the effects of ms on offspring depressive-like behaviors, but mechanisms in humans remain unclear. |
2023-07-01 |
2023-08-14 |
human |
| Zohreh Tavassoli, Mohammad Javan, Narges Hosseinmardi, Yaghoub Fathollah. Electrical impulses evoked activity patterns in ventral tegmental area and locus coeruleus modulate endogenous and learning-dependent disparity of cell proliferation along the mouse dentate gyrus. IBRO neuroscience reports. vol 14. 2023-06-30. PMID:37388501. |
cell proliferation was measured in the dorsal (ddg), intermediate (idg) and ventral (vdg) dentate gyrus (dg) using ki67 immunohistochemistry. |
2023-06-30 |
2023-08-14 |
mouse |
| Feng Zhang, Kijun Yoon, Nam-Shik Kim, Guo-Li Ming, Hongjun Son. Cell-autonomous and non-cell-autonomous roles of NKCC1 in regulating neural stem cell quiescence in the hippocampal dentate gyrus. Stem cell reports. 2023-06-30. PMID:37390823. |
how nscs in the dentate gyrus (dg) of the hippocampus acquire their quiescence during early postnatal stages and continuously maintain quiescence in adulthood is poorly understood. |
2023-06-30 |
2023-08-14 |
Not clear |
| Jie Xu, Bowen Zheng, Yanmei Ma, Xiaopeng Zhang, Jianhua Cheng, Jing Yang, Peng Li, Jianzhong Zhang, Li Jing, Fang X. PI3K-AKT-mTOR signaling pathway regulates autophagy of hippocampal neurons in diabetic rats with chronic unpredictable mild stress. Behavioural brain research. 2023-06-30. PMID:37390967. |
the number of pyknotic neurons at cornu ammonis 1 (ca1) and dentate gyrus (dg) of the hippocampus in t2dd was significantly increased compared with cums and t2dm groups. |
2023-06-30 |
2023-08-14 |
rat |
| Yan Luan, Hanyue Zhang, Kaige Ma, Yingfei Liu, Haixia Lu, Xinlin Chen, Yong Liu, Zhichao Zhan. CCN3/NOV Regulates Proliferation and Neuronal Differentiation in Mouse Hippocampal Neural Stem Cells via the Activation of the Notch/PTEN/AKT Pathway. International journal of molecular sciences. vol 24. issue 12. 2023-06-28. PMID:37373471. |
additionally, in vivo results showed that the injection of ccn3 in the dentate gyrus (dg) increased ki-67- and sox2-positive cells while decreasing neuron-specific class iii beta-tubulin (tuj1) and doublecortin (dcx)-positive cells. |
2023-06-28 |
2023-08-14 |
mouse |
| Rita Chaaya, Joel R Steele, Brian G Oliver, Hui Chen, Rita Machaalan. Effects of e-vapour and high-fat diet on the immunohistochemical staining of nicotinic acetylcholine receptors, apoptosis, microglia and astrocytes in the adult male mouse hippocampus. Journal of chemical neuroanatomy. 2023-06-21. PMID:37343645. |
this study, using a mouse model, investigated the effects of exposure to e-vapour (± nicotine) and hfd (43% fat) consumption, on the expression of nicotinic acetylcholine receptor (nachr) subunits α3, α4, α7 and β2, apoptosis markers caspase-3 and tunel, microglial marker iba-1, and astrocyte marker gfap, in hippocampal subregions of dentate gyrus (dg) and cornu ammonis (ca) 1-3. |
2023-06-21 |
2023-08-14 |
mouse |
| Sanghee Yun, Ivan Soler, Fionya H Tran, Harley A Haas, Raymon Shi, Grace L Bancroft, Maiko Suarez, Christopher R de Santis, Ryan P Reynolds, Amelia J Eisc. Behavioral pattern separation and cognitive flexibility are enhanced in a mouse model of increased lateral entorhinal cortex-dentate gyrus circuit activity. Frontiers in behavioral neuroscience. vol 17. 2023-06-16. PMID:37324519. |
in humans and mice, discrimination and adaptation rely on the integrity of the hippocampal dentate gyrus (dg) which receives glutamatergic input from the entorhinal cortex (ec), including the lateral ec (lec). |
2023-06-16 |
2023-08-14 |
mouse |
| Guo Xiang, Xia Liu, Jiangong Wang, Shunshun Lu, Meng Yu, Yuhan Zhang, Bin Sun, Bin Huang, Xin-Yun Lu, Xingang Li, Di Zhan. Peroxisome proliferator-activated receptor-α activation facilitates contextual fear extinction and modulates intrinsic excitability of dentate gyrus neurons. Translational psychiatry. vol 13. issue 1. 2023-06-15. PMID:37322045. |
the dentate gyrus (dg) of the hippocampus encodes contextual information associated with fear, and cell activity in the dg is required for acquisition and extinction of contextual fear. |
2023-06-15 |
2023-08-14 |
mouse |
| Mia Borzello, Steve Ramirez, Alessandro Treves, Inah Lee, Helen Scharfman, Craig Stark, James J Knierim, Lara M Range. Assessments of dentate gyrus function: discoveries and debates. Nature reviews. Neuroscience. 2023-06-14. PMID:37316588. |
there has been considerable speculation regarding the function of the dentate gyrus (dg) - a subregion of the mammalian hippocampus - in learning and memory. |
2023-06-14 |
2023-08-14 |
Not clear |
| Maria Pina Serra, Francesco Sanna, Marianna Boi, Marcello Trucas, Alberto Fernández-Teruel, Maria Giuseppa Corda, Osvaldo Giorgi, Marina Quart. Effects of Tail Pinch on BDNF and trkB Expression in the Hippocampus of Roman Low- (RLA) and High-Avoidance (RHA) Rats. International journal of molecular sciences. vol 24. issue 11. 2023-06-11. PMID:37298449. |
immunohistochemical assays, carried out in parallel to assess the location of changes revealed by the wb, showed that, in the dhc, tp increases bdnf-like immunoreactivity (li) in the ca2 sector of the ammon's horn of both roman lines and in the ca3 sector of the ammon's horn of rla rats while, in the dentate gyrus (dg), tp increases trkb-li in rha rats. |
2023-06-11 |
2023-08-14 |
human |
| Samira Choopani, Bahereh Kiani, Shayan Aliakbari, Jalal Babaie, Majid Golkar, Hamid Gholami Pourbadie, Mohammad Sayya. Latent toxoplasmosis impairs learning and memory yet strengthens short-term and long-term hippocampal synaptic plasticity at perforant pathway-dentate gyrus, and Schaffer collatterals-CA1 synapses. Scientific reports. vol 13. issue 1. 2023-06-02. PMID:37268701. |
eight weeks after infection, stp was assessed in dentate gyrus (dg) and ca1 by double pulse stimulation of perforant pathway and shaffer collaterals, respectively. |
2023-06-02 |
2023-08-14 |
rat |
| Virendra Tiwari, Akanksha Mishra, Sonu Singh, Shubha Shukl. Crosstalk between Adult Hippocampal Neurogenesis and Its Role in Alzheimer's Disease. ACS chemical neuroscience. 2023-06-01. PMID:37261380. |
neurogenesis in adult brain is associated with synaptic plasticity, learning, and memory in dentate gyrus (dg) of hippocampus and olfactory bulb. |
2023-06-01 |
2023-08-14 |
Not clear |
| Chuanfeng Tang, Qiaona Wang, Jingyan Shen, Congying Wang, Hong Ding, Shiyu Wen, Fan Yang, Ruiqing Jiao, Xingxin Wu, Jianmei Li, Lingdong Kon. Neuron stem cell NLRP6 sustains hippocampal neurogenesis to resist stress-induced depression. Acta pharmaceutica Sinica. B. vol 13. issue 5. 2023-05-30. PMID:37250149. |
neurogenesis decline in hippocampal dentate gyrus (dg) participates in stress-induced depressive-like behaviors, but the underlying mechanism remains poorly understood. |
2023-05-30 |
2023-08-14 |
mouse |
| Ya-Xin Sun, Yun-Ai Su, Qi Wang, Jia-Ya Zheng, Chen-Chen Zhang, Ting Wang, Xiao Liu, Yu-Nu Ma, Xue-Xin Li, Xian-Qiang Zhang, Xiao-Meng Xie, Xiao-Dong Wang, Ji-Tao Li, Tian-Mei S. The causal involvement of the BDNF-TrkB pathway in dentate gyrus in early-life stress-induced cognitive deficits in male mice. Translational psychiatry. vol 13. issue 1. 2023-05-24. PMID:37225683. |
in this study, we carried out eight experiments using male mice to examine the causal involvement of the bdnf-trkb pathway in dentate gyrus (dg) and the therapeutic effects of the trkb agonist (7,8-dhf) in els-induced cognitive deficits. |
2023-05-24 |
2023-08-14 |
mouse |
| Elissavet Chartampila, Karim S Elayouby, Paige Leary, John J LaFrancois, David Alcantara-Gonzalez, Swati Jain, Kasey Gerencer, Justin J Botterill, Stephen D Ginsberg, Helen E Scharfma. Choline supplementation in early life improves and low levels of choline can impair outcomes in a mouse model of Alzheimer's disease. bioRxiv : the preprint server for biology. 2023-05-23. PMID:37214805. |
hyperexcitability is also reflected by elevated expression of the transcription factor Δfosb in the principal cells of the dentate gyrus (dg), granule cells (gcs). |
2023-05-23 |
2023-08-14 |
mouse |
| Chiara Criscuolo, Elissavet Chartampila, Stephen D Ginsberg, Helen E Scharfma. Stability of dentate gyrus granule cell mossy fiber BDNF protein expression with age and resistance of granule cells to Alzheimer's disease neuropathology in a mouse model. bioRxiv : the preprint server for biology. 2023-05-23. PMID:37214931. |
however, the location where hippocampal bdnf protein is most highly expressed, the mossy fiber (mf) axons of dentate gyrus (dg) granule cells (gcs), has been understudied, and never in controlled |
2023-05-23 |
2023-08-14 |
mouse |
| Hu Meng, Qiongwei Li, Jinxin Wang, Weihua Yue, Dai Zhang, Xiaoxuan Sun, Lifang Wang, Jun L. The expansion of newborn neurons in hippocampus improves social recognition deficit in a mouse model of autism. Frontiers in psychiatry. vol 14. 2023-05-23. PMID:37215664. |
our previous study found that the deletion of high-risk gene autism susceptibility 2 (auts2) in mice led to dentate gyrus (dg) hypoplasia that highly associated with impaired social novelty recognition. |
2023-05-23 |
2023-08-14 |
mouse |
| Michelle C Gulfo, Joseph J Lebowitz, Czarina Ramos, Dong-Woo Hwang, Kaoutsar Nasrallah, Pablo E Castill. Dopamine D2 receptors in mossy cells reduce excitatory transmission and are essential for hippocampal function. bioRxiv : the preprint server for biology. 2023-05-19. PMID:37205586. |
hilar mossy cells (mcs) are principal excitatory neurons of the dentate gyrus (dg) that play critical roles in hippocampal function and have been implicated in brain disorders such as anxiety and epilepsy. |
2023-05-19 |
2023-08-14 |
Not clear |